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Volumn 34, Issue 9, 2014, Pages 1564-1575

Thyroid hormone signaling in vivo requires a balance between coactivators and corepressors

Author keywords

[No Author keywords available]

Indexed keywords

LIOTHYRONINE; NUCLEAR RECEPTOR COACTIVATOR; NUCLEAR RECEPTOR COACTIVATOR 2; NUCLEAR RECEPTOR COREPRESSOR; RECEPTOR INTERACTING PROTEIN 140; STEROID RECEPTOR COACTIVATOR 1; THYROID HORMONE; THYROID HORMONE RECEPTOR BETA; THYROTROPIN; TRIIODOTHYRONINE DERIVATIVE;

EID: 84897547500     PISSN: 02707306     EISSN: 10985549     Source Type: Journal    
DOI: 10.1128/MCB.00129-14     Document Type: Article
Times cited : (45)

References (57)
  • 1
    • 84865439311 scopus 로고    scopus 로고
    • Minireview: the neural regulation of the hypothalamic-pituitary-thyroid axis
    • Costa-e-Sousa RH, Hollenberg AN. 2012. Minireview: the neural regulation of the hypothalamic-pituitary-thyroid axis. Endocrinology 153: 4128-4135. http://dx.doi.org/10.1210/en.2012-1467.
    • (2012) Endocrinology , vol.153 , pp. 4128-4135
    • Costa-e-Sousa, R.H.1    Hollenberg, A.N.2
  • 2
    • 67650233318 scopus 로고    scopus 로고
    • Minireview: thyrotropinreleasing hormone and the thyroid hormone feedback mechanism
    • Chiamolera MI, Wondisford FE. 2009. Minireview: thyrotropinreleasing hormone and the thyroid hormone feedback mechanism. Endocrinology 150:1091-1096. http://dx.doi.org/10.1210/en.2008-1795.
    • (2009) Endocrinology , vol.150 , pp. 1091-1096
    • Chiamolera, M.I.1    Wondisford, F.E.2
  • 3
    • 0033859843 scopus 로고    scopus 로고
    • The mechanism of action of thyroid hormones
    • Zhang J, Lazar MA. 2000. The mechanism of action of thyroid hormones. Annu. Rev. Physiol. 62:439-466. http://dx.doi.org/10.1146/annurev.physiol.62.1.439.
    • (2000) Annu. Rev. Physiol. , vol.62 , pp. 439-466
    • Zhang, J.1    Lazar, M.A.2
  • 4
    • 0034964207 scopus 로고    scopus 로고
    • Physiological and molecular basis of thyroid hormone action
    • Yen PM. 2001. Physiological and molecular basis of thyroid hormone action. Physiol. Rev. 81:1097-1142.
    • (2001) Physiol. Rev. , vol.81 , pp. 1097-1142
    • Yen, P.M.1
  • 5
    • 77953639982 scopus 로고    scopus 로고
    • Molecular aspects of thyroid hormone actions
    • Cheng SY, Leonard JL, Davis PJ. 2010. Molecular aspects of thyroid hormone actions. Endocr. Rev. 31:139-170. http://dx.doi.org/10.1210/er.2009-0007.
    • (2010) Endocr. Rev. , vol.31 , pp. 139-170
    • Cheng, S.Y.1    Leonard, J.L.2    Davis, P.J.3
  • 6
    • 0028846193 scopus 로고
    • Sequence and characterization of a coactivator for the steroid hormone receptor superfamily
    • Onate SA, Tsai SY, Tsai MJ, O'Malley BW. 1995. Sequence and characterization of a coactivator for the steroid hormone receptor superfamily. Science 270:1354-1357. http://dx.doi.org/10.1126/science.270.5240.1354.
    • (1995) Science , vol.270 , pp. 1354-1357
    • Onate, S.A.1    Tsai, S.Y.2    Tsai, M.J.3    O'Malley, B.W.4
  • 7
    • 0033305547 scopus 로고    scopus 로고
    • Nuclear receptor coregulators: cellular and molecular biology
    • McKenna NJ, Lanz RB, O'Malley BW. 1999. Nuclear receptor coregulators: cellular and molecular biology. Endocr. Rev. 20:321-344. http://dx.doi.org/10.1210/edrv.20.3.0366.
    • (1999) Endocr. Rev. , vol.20 , pp. 321-344
    • McKenna, N.J.1    Lanz, R.B.2    O'Malley, B.W.3
  • 8
    • 0037154974 scopus 로고    scopus 로고
    • Combinatorial control of gene expression by nuclear receptors and coregulators
    • McKenna NJ, O'Malley BW. 2002. Combinatorial control of gene expression by nuclear receptors and coregulators. Cell 108:465-474. http://dx.doi.org/10.1016/S0092-8674(02)00641-4.
    • (2002) Cell , vol.108 , pp. 465-474
    • McKenna, N.J.1    O'Malley, B.W.2
  • 9
    • 0034615669 scopus 로고    scopus 로고
    • The SRC family of nuclear receptor coactivators
    • Leo C, Chen JD. 2000. The SRC family of nuclear receptor coactivators. Gene 245:1-11. http://dx.doi.org/10.1016/S0378-1119(00)00024-X.
    • (2000) Gene , vol.245 , pp. 1-11
    • Leo, C.1    Chen, J.D.2
  • 10
    • 0036515648 scopus 로고    scopus 로고
    • Nuclear receptor coregulators: multiple modes of modification
    • Hermanson O, Glass CK, Rosenfeld MG. 2002. Nuclear receptor coregulators: multiple modes of modification. Trends Endocrinol. Metab. 13:55-60. http://dx.doi.org/10.1016/S1043-2760(01)00527-6.
    • (2002) Trends Endocrinol. Metab. , vol.13 , pp. 55-60
    • Hermanson, O.1    Glass, C.K.2    Rosenfeld, M.G.3
  • 12
    • 0042334873 scopus 로고    scopus 로고
    • Review of the in vivo functions of the p160 steroid receptor coactivator family
    • Xu J, Li Q. 2003. Review of the in vivo functions of the p160 steroid receptor coactivator family. Mol. Endocrinol. 17:1681-1692. http://dx.doi.org/10.1210/me.2003-0116.
    • (2003) Mol. Endocrinol. , vol.17 , pp. 1681-1692
    • Xu, J.1    Li, Q.2
  • 14
    • 0030959244 scopus 로고    scopus 로고
    • Role for N-CoR and histone deacetylase in Sin3-mediated transcriptional repression
    • Alland L, Muhle R, Hou H, Jr, Potes J, Chin L, Schreiber-Agus N, DePinho RA. 1997. Role for N-CoR and histone deacetylase in Sin3-mediated transcriptional repression. Nature 387:49-55. http://dx.doi.org/10.1038/387049a0.
    • (1997) Nature , vol.387 , pp. 49-55
    • Alland, L.1    Muhle, R.2    Hou Jr., H.3    Potes, J.4    Chin, L.5    Schreiber-Agus, N.6    DePinho, R.A.7
  • 15
    • 0035724413 scopus 로고    scopus 로고
    • The SMRT and N-CoR corepressors are activating cofactors for histone deacetylase 3
    • Guenther MG, Barak O, Lazar MA. 2001. The SMRT and N-CoR corepressors are activating cofactors for histone deacetylase 3. Mol. Cell. Biol. 21:6091-6101. http://dx.doi.org/10.1128/MCB.21.18.6091-6101.2001.
    • (2001) Mol. Cell. Biol. , vol.21 , pp. 6091-6101
    • Guenther, M.G.1    Barak, O.2    Lazar, M.A.3
  • 17
    • 0030953186 scopus 로고    scopus 로고
    • Nuclear receptor repression mediated by a complex containing SMRT, mSin3A, and histone deacetylase
    • Nagy L, Kao HY, Chakravarti D, Lin RJ, Hassig CA, Ayer DE, Schreiber SL, Evans RM. 1997. Nuclear receptor repression mediated by a complex containing SMRT, mSin3A, and histone deacetylase. Cell 89:373-380. http://dx.doi.org/10.1016/S0092-8674(00)80218-4.
    • (1997) Cell , vol.89 , pp. 373-380
    • Nagy, L.1    Kao, H.Y.2    Chakravarti, D.3    Lin, R.J.4    Hassig, C.A.5    Ayer, D.E.6    Schreiber, S.L.7    Evans, R.M.8
  • 18
    • 75649135910 scopus 로고    scopus 로고
    • Deconstructing repression: evolving models of co-repressor action
    • Perissi V, Jepsen K, Glass CK, Rosenfeld MG. 2010. Deconstructing repression: evolving models of co-repressor action. Nat. Rev. Genet. 11: 109-123. http://dx.doi.org/10.1038/nrg2736.
    • (2010) Nat. Rev. Genet. , vol.11 , pp. 109-123
    • Perissi, V.1    Jepsen, K.2    Glass, C.K.3    Rosenfeld, M.G.4
  • 19
    • 79952775519 scopus 로고    scopus 로고
    • Corepressor SMRT promotes oxidative phosphorylation in adipose tissue and protects against diet-induced obesity and insulin resistance
    • Fang S, Suh JM, Atkins AR, Hong SH, Leblanc M, Nofsinger RR, Yu RT, Downes M, Evans RM. 2011. Corepressor SMRT promotes oxidative phosphorylation in adipose tissue and protects against diet-induced obesity and insulin resistance. Proc. Natl. Acad. Sci. U. S. A. 108:3412-3417. http://dx.doi.org/10.1073/pnas.1017707108.
    • (2011) Proc. Natl. Acad. Sci. U. S. A. , vol.108 , pp. 3412-3417
    • Fang, S.1    Suh, J.M.2    Atkins, A.R.3    Hong, S.H.4    Leblanc, M.5    Nofsinger, R.R.6    Yu, R.T.7    Downes, M.8    Evans, R.M.9
  • 20
    • 0033118328 scopus 로고    scopus 로고
    • Mice deficient in the steroid receptor co-activator 1 (SRC-1) are resistant to thyroid hormone
    • Weiss RE, Xu J, Ning G, Pohlenz J, O'Malley BW, Refetoff S. 1999. Mice deficient in the steroid receptor co-activator 1 (SRC-1) are resistant to thyroid hormone. EMBO J. 18:1900-1904. http://dx.doi.org/10.1093/emboj/18.7.1900.
    • (1999) EMBO J. , vol.18 , pp. 1900-1904
    • Weiss, R.E.1    Xu, J.2    Ning, G.3    Pohlenz, J.4    O'Malley, B.W.5    Refetoff, S.6
  • 25
    • 84866749166 scopus 로고    scopus 로고
    • The thyroid axis is regulated by NCoR1 via its actions in the pituitary
    • Costa-e-Sousa RH, Astapova I, Ye F, Wondisford FE, Hollenberg AN. 2012. The thyroid axis is regulated by NCoR1 via its actions in the pituitary. Endocrinology 153:5049-5057. http://dx.doi.org/10.1210/en.2012-1504.
    • (2012) Endocrinology , vol.153 , pp. 5049-5057
    • Costa-e-Sousa, R.H.1    Astapova, I.2    Ye, F.3    Wondisford, F.E.4    Hollenberg, A.N.5
  • 26
    • 34547483059 scopus 로고    scopus 로고
    • Response of SMRT (silencing mediator of retinoic acid and thyroid hormone receptor) and N-CoR (nuclear receptor corepressor) corepressors to mitogen-activated protein kinase kinase kinase cascades is determined by alternative mRNA splicing
    • Jonas BA, Varlakhanova N, Hayakawa F, Goodson M, Privalsky ML. 2007. Response of SMRT (silencing mediator of retinoic acid and thyroid hormone receptor) and N-CoR (nuclear receptor corepressor) corepressors to mitogen-activated protein kinase kinase kinase cascades is determined by alternative mRNA splicing. Mol. Endocrinol. 21:1924-1939. http://dx.doi.org/10.1210/me.2007-0035.
    • (2007) Mol. Endocrinol. , vol.21 , pp. 1924-1939
    • Jonas, B.A.1    Varlakhanova, N.2    Hayakawa, F.3    Goodson, M.4    Privalsky, M.L.5
  • 27
    • 0037312913 scopus 로고    scopus 로고
    • Determination of nuclear receptor corepressor interactions with the thyroid hormone receptor
    • Makowski A, Brzostek S, Cohen RN, Hollenberg AN. 2003. Determination of nuclear receptor corepressor interactions with the thyroid hormone receptor. Mol. Endocrinol. 17:273-286. http://dx.doi.org/10.1210/me.2002-0310.
    • (2003) Mol. Endocrinol. , vol.17 , pp. 273-286
    • Makowski, A.1    Brzostek, S.2    Cohen, R.N.3    Hollenberg, A.N.4
  • 28
    • 67349242981 scopus 로고    scopus 로고
    • The thyroid hormone receptor recruits NCoR via widely spaced receptor-interacting domains
    • Astapova I, Dordek MF, Hollenberg AN. 2009. The thyroid hormone receptor recruits NCoR via widely spaced receptor-interacting domains. Mol. Cell. Endocrinol. 307:83-88. http://dx.doi.org/10.1016/j.mce.2009.02.028.
    • (2009) Mol. Cell. Endocrinol. , vol.307 , pp. 83-88
    • Astapova, I.1    Dordek, M.F.2    Hollenberg, A.N.3
  • 29
    • 0030991152 scopus 로고    scopus 로고
    • Stoichiometric and steric principles governing repression by nuclear hormone receptors
    • Zamir I, Zhang J, Lazar MA. 1997. Stoichiometric and steric principles governing repression by nuclear hormone receptors. Genes Dev. 11:835-846. http://dx.doi.org/10.1101/gad.11.7.835.
    • (1997) Genes Dev. , vol.11 , pp. 835-846
    • Zamir, I.1    Zhang, J.2    Lazar, M.A.3
  • 30
    • 0034536085 scopus 로고    scopus 로고
    • The nuclear receptor corepressor (N-CoR) contains three isoleucine motifs (I/LXXII) that serve as receptor interaction domains (IDs)
    • Webb P, Anderson CM, Valentine C, Nguyen P, Marimuthu A, West BL, Baxter JD, Kushner PJ. 2000. The nuclear receptor corepressor (N-CoR) contains three isoleucine motifs (I/LXXII) that serve as receptor interaction domains (IDs). Mol. Endocrinol. 14:1976-1985. http://dx.doi.org/10.1210/me.14.12.1976.
    • (2000) Mol. Endocrinol. , vol.14 , pp. 1976-1985
    • Webb, P.1    Anderson, C.M.2    Valentine, C.3    Nguyen, P.4    Marimuthu, A.5    West, B.L.6    Baxter, J.D.7    Kushner, P.J.8
  • 31
    • 0034975063 scopus 로고    scopus 로고
    • The specificity of interactions between nuclear hormone receptors and corepressors is mediated by distinct amino acid sequences within the interacting domains
    • Cohen RN, Brzostek S, Kim B, Chorev M, Wondisford FE, Hollenberg AN. 2001. The specificity of interactions between nuclear hormone receptors and corepressors is mediated by distinct amino acid sequences within the interacting domains. Mol. Endocrinol. 15:1049-1061. http://dx.doi.org/10.1210/me.15.7.1049.
    • (2001) Mol. Endocrinol. , vol.15 , pp. 1049-1061
    • Cohen, R.N.1    Brzostek, S.2    Kim, B.3    Chorev, M.4    Wondisford, F.E.5    Hollenberg, A.N.6
  • 32
    • 0034465602 scopus 로고    scopus 로고
    • The nuclear corepressors recognize distinct nuclear receptor complexes
    • Cohen RN, Putney A, Wondisford FE, Hollenberg AN. 2000. The nuclear corepressors recognize distinct nuclear receptor complexes. Mol. Endocrinol. 14:900-914. http://dx.doi.org/10.1210/me.14.6.900.
    • (2000) Mol. Endocrinol. , vol.14 , pp. 900-914
    • Cohen, R.N.1    Putney, A.2    Wondisford, F.E.3    Hollenberg, A.N.4
  • 34
    • 77954832705 scopus 로고    scopus 로고
    • The interaction between nuclear receptor corepressor and histone deacetylase 3 regulates both positive and negative thyroid hormone action in vivo
    • You SH, Liao X, Weiss RE, Lazar MA. 2010. The interaction between nuclear receptor corepressor and histone deacetylase 3 regulates both positive and negative thyroid hormone action in vivo. Mol. Endocrinol. 24: 1359-1367. http://dx.doi.org/10.1210/me.2009-0501.
    • (2010) Mol. Endocrinol. , vol.24 , pp. 1359-1367
    • You, S.H.1    Liao, X.2    Weiss, R.E.3    Lazar, M.A.4
  • 35
    • 0027241002 scopus 로고
    • The syndromes of resistance to thyroid hormone
    • Refetoff S, Weiss RE, Usala SJ. 1993. The syndromes of resistance to thyroid hormone. Endocr. Rev. 14:348-399. http://dx.doi.org/10.1210/edrv-14-3-348.
    • (1993) Endocr. Rev. , vol.14 , pp. 348-399
    • Refetoff, S.1    Weiss, R.E.2    Usala, S.J.3
  • 36
    • 0030901251 scopus 로고    scopus 로고
    • Phenotype differences of resistance to thyroid hormone in two unrelated families with an identical mutation in the thyroid hormone receptor beta gene (R320C)
    • Weiss RE, Tunca H, Knapple WL, Faas FH, Refetoff S. 1997. Phenotype differences of resistance to thyroid hormone in two unrelated families with an identical mutation in the thyroid hormone receptor beta gene (R320C). Thyroid 7:35-38. http://dx.doi.org/10.1089/thy.1997.7.35.
    • (1997) Thyroid , vol.7 , pp. 35-38
    • Weiss, R.E.1    Tunca, H.2    Knapple, W.L.3    Faas, F.H.4    Refetoff, S.5
  • 37
    • 0026320853 scopus 로고
    • Characterization of seven novel mutations of the c-erbA beta gene in unrelated kindreds with generalized thyroid hormone resistance. Evidence for two "hot spot" regions of the ligand binding domain
    • Parrilla R, Mixson AJ, McPherson JA, McClaskey JH, Weintraub BD. 1991. Characterization of seven novel mutations of the c-erbA beta gene in unrelated kindreds with generalized thyroid hormone resistance. Evidence for two "hot spot" regions of the ligand binding domain. J. Clin. Invest. 88:2123-2130.
    • (1991) J. Clin. Invest. , vol.88 , pp. 2123-2130
    • Parrilla, R.1    Mixson, A.J.2    McPherson, J.A.3    McClaskey, J.H.4    Weintraub, B.D.5
  • 42
    • 0032549744 scopus 로고    scopus 로고
    • Partial hormone resistance in mice with disruption of the steroid receptor coactivator-1 (SRC-1) gene
    • Xu J, Qiu Y, DeMayo FJ, Tsai SY, Tsai MJ, O'Malley BW. 1998. Partial hormone resistance in mice with disruption of the steroid receptor coactivator-1 (SRC-1) gene. Science 279:1922-1925. http://dx.doi.org/10.1126/science.279.5358.1922.
    • (1998) Science , vol.279 , pp. 1922-1925
    • Xu, J.1    Qiu, Y.2    DeMayo, F.J.3    Tsai, S.Y.4    Tsai, M.J.5    O'Malley, B.W.6
  • 46
    • 66449091275 scopus 로고    scopus 로고
    • STAT3 targets the regulatory regions of gluconeogenic genes in vivo
    • Ramadoss P, Unger-Smith NE, Lam FS, Hollenberg AN. 2009. STAT3 targets the regulatory regions of gluconeogenic genes in vivo. Mol. Endocrinol. 23:827-837. http://dx.doi.org/10.1210/me.2008-0264.
    • (2009) Mol. Endocrinol. , vol.23 , pp. 827-837
    • Ramadoss, P.1    Unger-Smith, N.E.2    Lam, F.S.3    Hollenberg, A.N.4
  • 47
    • 84892660787 scopus 로고    scopus 로고
    • Novel mechanism of positive versus negative regulation by thyroid hormone receptor beta 1 (TRbeta1) identified by genome-wide profiling of binding sites in mouse liver
    • Ramadoss P, Abraham BJ, Tsai L, Zhou Y, Costa-e-Sousa RH, Ye F, Bilban M, Zhao K, Hollenberg AN. 2014. Novel mechanism of positive versus negative regulation by thyroid hormone receptor beta 1 (TRbeta1) identified by genome-wide profiling of binding sites in mouse liver. J. Biol. Chem. 289:1313-1328. http://dx.doi.org/10.1074/jbc.M113.521450.
    • (2014) J. Biol. Chem. , vol.289 , pp. 1313-1328
    • Ramadoss, P.1    Abraham, B.J.2    Tsai, L.3    Zhou, Y.4    Costa-e-Sousa, R.H.5    Ye, F.6    Bilban, M.7    Zhao, K.8    Hollenberg, A.N.9
  • 49
    • 67651183864 scopus 로고    scopus 로고
    • In vivo interaction of steroid receptor coactivator (SRC)-1 and the activation function-2 domain of the thyroid hormone receptor (TR) beta in TRbeta E457A knock-in and SRC-1 knockout mice
    • Alonso M, Goodwin C, Liao X, Ortiga-Carvalho T, Machado DS, Wondisford FE, Refetoff S, Weiss RE. 2009. In vivo interaction of steroid receptor coactivator (SRC)-1 and the activation function-2 domain of the thyroid hormone receptor (TR) beta in TRbeta E457A knock-in and SRC-1 knockout mice. Endocrinology 150:3927-3934. http://dx.doi.org/10.1210/en.2009-0093.
    • (2009) Endocrinology , vol.150 , pp. 3927-3934
    • Alonso, M.1    Goodwin, C.2    Liao, X.3    Ortiga-Carvalho, T.4    Machado, D.S.5    Wondisford, F.E.6    Refetoff, S.7    Weiss, R.E.8
  • 50
    • 0042922455 scopus 로고    scopus 로고
    • Modulation by steroid receptor coactivator-1 of target-tissue responsiveness in resistance to thyroid hormone
    • Kamiya Y, Zhang XY, Ying H, Kato Y, Willingham MC, Xu J, O'Malley BW, Cheng SY. 2003. Modulation by steroid receptor coactivator-1 of target-tissue responsiveness in resistance to thyroid hormone. Endocrinology 144:4144-4153. http://dx.doi.org/10.1210/en.2003-0239.
    • (2003) Endocrinology , vol.144 , pp. 4144-4153
    • Kamiya, Y.1    Zhang, X.Y.2    Ying, H.3    Kato, Y.4    Willingham, M.C.5    Xu, J.6    O'Malley, B.W.7    Cheng, S.Y.8
  • 52
    • 0036212262 scopus 로고    scopus 로고
    • Steroid receptor coactivator-1 deficiency causes variable alterations in the modulation of T(3)-regulated transcription of genes in vivo
    • Takeuchi Y, Murata Y, Sadow P, Hayashi Y, Seo H, Xu J, O'Malley BW, Weiss RE, Refetoff S. 2002. Steroid receptor coactivator-1 deficiency causes variable alterations in the modulation of T(3)-regulated transcription of genes in vivo. Endocrinology 143:1346-1352. http://dx.doi.org/10.1210/en.143.4.1346.
    • (2002) Endocrinology , vol.143 , pp. 1346-1352
    • Takeuchi, Y.1    Murata, Y.2    Sadow, P.3    Hayashi, Y.4    Seo, H.5    Xu, J.6    O'Malley, B.W.7    Weiss, R.E.8    Refetoff, S.9
  • 53
    • 0036212356 scopus 로고    scopus 로고
    • Thyroid function in mice with compound heterozygous and homozygous disruptions of SRC-1 and TIF-2 coactivators: evidence for haploinsufficiency
    • Weiss RE, Gehin M, Xu J, Sadow PM, O'Malley BW, Chambon P, Refetoff S. 2002. Thyroid function in mice with compound heterozygous and homozygous disruptions of SRC-1 and TIF-2 coactivators: evidence for haploinsufficiency. Endocrinology 143:1554-1557. http://dx.doi.org/10.1210/en.143.4.1554.
    • (2002) Endocrinology , vol.143 , pp. 1554-1557
    • Weiss, R.E.1    Gehin, M.2    Xu, J.3    Sadow, P.M.4    O'Malley, B.W.5    Chambon, P.6    Refetoff, S.7
  • 57
    • 84859416479 scopus 로고    scopus 로고
    • Metabolic health and nuclear-receptor sensitivity
    • Hollenberg AN. 2012. Metabolic health and nuclear-receptor sensitivity. N. Engl. J. Med. 366:1345-1347. http://dx.doi.org/10.1056/NEJMcibr 1114529.
    • (2012) N. Engl. J. Med. , vol.366 , pp. 1345-1347
    • Hollenberg, A.N.1


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