-
1
-
-
0028172989
-
13C-nuclear magnetic resonance spectroscopy studies of hepatic glucose metabolism in normal subjects and subjects with insulin-dependent diabetes mellitus
-
Cline GW, Rothman DL, Magnusson I, Katz LD, Shulman GI 1994 13C-nuclear magnetic resonance spectroscopy studies of hepatic glucose metabolism in normal subjects and subjects with insulin-dependent diabetes mellitus. J Clin Invest 94:2369-2376 (Pubitemid 24379610)
-
(1994)
Journal of Clinical Investigation
, vol.94
, Issue.6
, pp. 2369-2376
-
-
Cline, G.W.1
Rothman, D.L.2
Magnusson, I.3
Katz, L.D.4
Shulman, G.I.5
-
2
-
-
0026591523
-
Role of liver in pathophysiology of NIDDM
-
Consoli A 1992 Role of liver in pathophysiology of NIDDM. Diabetes Care 15:430-441
-
(1992)
Diabetes Care
, vol.15
, pp. 430-441
-
-
Consoli, A.1
-
3
-
-
0024511329
-
Predominant role of gluconeogenesis in increased hepatic glucose production in NIDDM
-
Consoli A, Nurjhan N, Capani F, Gerich J 1989 Predominant role of gluconeogenesis in increased hepatic glucose production in NIDDM. Diabetes 38:550-557 (Pubitemid 19125601)
-
(1989)
Diabetes
, vol.38
, Issue.5
, pp. 550-557
-
-
Consoli, A.1
Nurjhan, N.2
Capani, F.3
Gerich, J.4
-
4
-
-
11244335844
-
A distal region involving hepatocyte nuclear factor 4α and CAAT/Enhancer binding protein markedly potentiates the protein kinase a stimulation of the glucose-6-phosphate promoter
-
DOI 10.1210/me.2004-0105
-
Gautier-Stein A, Mithieux G, Rajas F 2005 A distal region involving hepatocyte nuclear factor 4α and CAAT/enhancer binding protein markedly potentiates the protein kinase A stimulation of the glucose-6-phosphatase promoter. Mol Endocrinol 19:163-174 (Pubitemid 40065967)
-
(2005)
Molecular Endocrinology
, vol.19
, Issue.1
, pp. 163-174
-
-
Gautier-Stein, A.1
Mithieux, G.2
Rajas, F.3
-
5
-
-
0030613787
-
The role of HNF1α, HNF3γ, and cyclic AMP in glucose-6-phosphatase gene activation
-
Lin B, Morris DW, Chou JY 1997 The role of HNF1α, HNF3γ, and cyclic AMP in glucose-6-phosphatase gene activation. Biochemistry 36:14096-14106
-
(1997)
Biochemistry
, vol.36
, pp. 14096-14106
-
-
Lin, B.1
Morris, D.W.2
Chou, J.Y.3
-
6
-
-
0026047305
-
Cyclic AMP induction of phosphoenolpyruvate carboxykinase (GTP) gene transcription is mediated by multiple promoter elements
-
Liu JS, Park EA, Gurney AL, Roesler WJ, Hanson RW 1991 Cyclic AMP induction of phosphoenolpyruvate carboxykinase (GTP) gene transcription is mediated by multiple promoter elements. J Biol Chem 266:19095-19102 (Pubitemid 21908197)
-
(1991)
Journal of Biological Chemistry
, vol.266
, Issue.28
, pp. 19095-19102
-
-
Liu, J.1
Park, E.A.2
Gurney, A.L.3
Roesler, W.J.4
Hanson, R.W.5
-
7
-
-
0027433708
-
Phosphorylated CREB binds specifically to the nuclear protein CBP
-
DOI 10.1038/365855a0
-
Chrivia JC, Kwok RP, Lamb N, Hagiwara M, Montminy MR, Goodman RH 1993 Phosphorylated CREB binds specifically to the nuclear protein CBP. Nature 365:855-859 (Pubitemid 23341031)
-
(1993)
Nature
, vol.365
, Issue.6449
, pp. 855-859
-
-
Chrivia, J.C.1
Kwok, R.P.S.2
Lamb, N.3
Hagiwara, M.4
Montminy, M.R.5
Goodman, R.H.6
-
8
-
-
0141922981
-
TORCs: Transducers of regulated CREB activity
-
DOI 10.1016/j.molcel.2003.08.013
-
Conkright MD, Canettieri G, Screaton R, Guzman E, Miraglia L, Hogenesch JB, Montminy M 2003 TORCs: transducers of regulated CREB activity. Mol Cell 12:413-423 (Pubitemid 37238928)
-
(2003)
Molecular Cell
, vol.12
, Issue.2
, pp. 413-423
-
-
Conkright, M.D.1
Canettieri, G.2
Screaton, R.3
Guzman, E.4
Miraglia, L.5
Hogenesch, J.B.6
Montminy, M.7
-
9
-
-
0028060029
-
Nuclear protein CBP is a coactivator for the transcription factor CREB
-
DOI 10.1038/370223a0
-
Kwok RP, Lundblad JR, Chrivia JC, Richards JP, Bächinger HP, Brennan RG, Roberts SG, Green MR, Goodman RH 1994 Nuclear protein CBP is a coactivator for the transcription factor CREB. Nature 370:223-226 (Pubitemid 24236779)
-
(1994)
Nature
, vol.370
, Issue.6486
, pp. 223-226
-
-
Kwok, R.P.S.1
Lundblad, J.R.2
Chrivia, J.C.3
Richards, J.P.4
Bachinger, H.P.5
Brennan, R.G.6
Roberts, S.G.E.7
Green, M.R.8
Goodman, R.H.9
-
10
-
-
34250814515
-
Cooperative interactions between CBP and TORC2 confer selectivity to CREB target gene expression
-
Ravnskjaer K, Kester H, Liu Y, Zhang X, Lee D, Yates 3rd JR, Montminy M 2007 Cooperative interactions between CBP and TORC2 confer selectivity to CREB target gene expression. EMBO J 26:2880-2889
-
(2007)
EMBO J
, vol.26
, pp. 2880-2889
-
-
Ravnskjaer, K.1
Kester, H.2
Liu, Y.3
Zhang, X.4
Lee, D.5
Yates III, J.R.6
Montminy, M.7
-
11
-
-
0025028899
-
Regulation of phosphoenolpyruvate carboxykinase gene expression by insulin. Use of the stable transfection approach to locate an insulin responsive sequence
-
Forest CD, O'Brien RM, Lucas PC, Magnuson MA, Granner DK 1990 Regulation of phosphoenolpyruvate carboxykinase gene expression by insulin. Use of the stable transfection approach to locate an insulin responsive sequence. Mol Endocrinol 4:1302-1310
-
(1990)
Mol Endocrinol
, vol.4
, pp. 1302-1310
-
-
Forest, C.D.1
O'Brien, R.M.2
Lucas, P.C.3
Magnuson, M.A.4
Granner, D.K.5
-
12
-
-
0023620040
-
Multihormonal regulation of phosphoenolpyruvate carboxykinase- chloramphenicol acetyltransferase fusion genes. Insulin's effects oppose those of cAMP and dexamethasone
-
Magnuson MA, Quinn PG, Granner DK 1987 Multihormonal regulation of phosphoenolpyruvate carboxykinase-chloramphenicol acetyltransferase fusion genes. Insulin's effects oppose those of cAMP and dexamethasone. J Biol Chem 262:14917-14920 (Pubitemid 17160168)
-
(1987)
Journal of Biological Chemistry
, vol.262
, Issue.31
, pp. 14917-14920
-
-
Magnuson, M.A.1
Quinn, P.G.2
Granner, D.K.3
-
13
-
-
0025160127
-
Identification of a sequence in the PEPCK gene that mediates a negative effect of insulin on transcription
-
O'Brien RM, Lucas PC, Forest CD, Magnuson MA, Granner DK 1990 Identification of a sequence in the PEPCK gene that mediates a negative effect of insulin on transcription. Science 249:533-537 (Pubitemid 20248896)
-
(1990)
Science
, vol.249
, Issue.4968
, pp. 533-537
-
-
O'Brien, R.M.1
Lucas, P.C.2
Forest, C.D.3
Magnuson, M.A.4
Granner, D.K.5
-
14
-
-
0141727772
-
Inhibition of Foxo1 function is associated with improved fasting glycemia in diabetic mice
-
Altomonte J, Richter A, Harbaran S, Suriawinata J, Nakae J, Thung SN, Meseck M, Accili D, Dong H 2003 Inhibition of Foxo1 function is associated with improved fasting glycemia in diabetic mice. Am J Physiol Endocrinol Metab 285:E718-E728 (Pubitemid 37176422)
-
(2003)
American Journal of Physiology - Endocrinology and Metabolism
, vol.285
, Issue.4
-
-
Altomonte, J.1
Richter, A.2
Harbaran, S.3
Suriawinata, J.4
Nakae, J.5
Thung, S.N.6
Meseck, M.7
Accili, D.8
Dong, H.9
-
15
-
-
0034806293
-
Differential regulation of endogenous glucose-6-phosphatase and phosphoenolpyruvate carboxykinase gene expression by the forkhead transcription factor FKHR in H4IIE-hepatoma cells
-
DOI 10.1006/bbrc.2001.5261
-
Barthel A, Schmoll D, Krüger KD, Bahrenberg G, Walther R, Roth RA, Joost HG 2001 Differential regulation of endogenous glucose-6-phosphatase and phosphoenolpyruvate carboxykinase gene expression by the forkhead transcription factor FKHR in H4IIE-hepatoma cells. Biochem Biophys Res Commun 285:897-902 (Pubitemid 32918020)
-
(2001)
Biochemical and Biophysical Research Communications
, vol.285
, Issue.4
, pp. 897-902
-
-
Barthel, A.1
Schmoll, D.2
Kruger, K.-D.3
Bahrenberg, G.4
Walther, R.5
Roth, R.A.6
Joost, H.-G.7
-
16
-
-
0038187621
-
Insulin-regulated hepatic gluconeogenesis through FOXO1-PGC-1α interaction
-
DOI 10.1038/nature01667
-
Puigserver P, Rhee J, Donovan J, Walkey CJ, Yoon JC, Oriente F, Kitamura Y, Altomonte J, Dong H, Accili D, Spiegelman BM 2003 Insulin-regulated hepatic gluconeogenesis through FOXO1-PGC-1α interaction. Nature 423:550-555 (Pubitemid 36648580)
-
(2003)
Nature
, vol.423
, Issue.6939
, pp. 550-555
-
-
Puigserver, P.1
Rhee, J.2
Donovan, J.3
Walkey, C.J.4
Yoon, J.C.5
Oriente, F.6
Kitamura, Y.7
Altomonte, J.8
Dong, H.9
Accili, D.10
Spiegelman, B.M.11
-
17
-
-
0034730660
-
Regulation of phosphoenolpyruvate carboxykinase and insulin-like growth factor-binding protein-1 gene expression by insulin. The role of winged helix/forkhead proteins
-
Hall RK, Yamasaki T, Kucera T, Waltner-Law M, O'Brien R, Granner DK 2000 Regulation of phosphoenolpyruvate carboxykinase and insulin-like growth factor-binding protein-1 gene expression by insulin. The role of winged helix/forkhead proteins. J Biol Chem 275:30169-30175
-
(2000)
J Biol Chem
, vol.275
, pp. 30169-30175
-
-
Hall, R.K.1
Yamasaki, T.2
Kucera, T.3
Waltner-Law, M.4
O'Brien, R.5
Granner, D.K.6
-
18
-
-
0038146897
-
The three insulin response sequences in the glucose-6-phosphatase catalytic subunit gene promoter are functionally distinct
-
DOI 10.1074/jbc.M212570200
-
Vander Kooi BT, Streeper RS, Svitek CA, Oeser JK, Powell DR, O'Brien RM 2003 The three insulin response sequences in the glucose-6-phosphatase catalytic subunit gene promoter are functionally distinct. J Biol Chem 278:11782-11793 (Pubitemid 36800147)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.14
, pp. 11782-11793
-
-
Vander Kooi, B.T.1
Streeper, R.S.2
Svitek, C.A.3
Oeser, J.K.4
Powell, D.R.5
O'Brien, R.M.6
-
19
-
-
0033595011
-
Protein kinase B/Akt-mediated phosphorylation promotes nuclear exclusion of the winged helix transcription factor FKHR1
-
Biggs 3rd WH, Meisenhelder J, Hunter T, Cavenee WK, Arden KC 1999 Protein kinase B/Akt-mediated phosphorylation promotes nuclear exclusion of the winged helix transcription factor FKHR1. Proc Natl Acad Sci USA 96:7421-7426
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 7421-7426
-
-
Biggs III, W.H.1
Meisenhelder, J.2
Hunter, T.3
Cavenee, W.K.4
Arden, K.C.5
-
20
-
-
0033546192
-
Phosphorylation of serine 256 by protein kinase B disrupts transactivation by FKHR and mediates effects of insulin on insulin-like growth factor-binding protein-1 promoter activity through a conserved insulin response sequence
-
Guo S, Rena G, Cichy S, He X, Cohen P, Unterman T 1999 Phosphorylation of serine 256 by protein kinase B disrupts transactivation by FKHR and mediates effects of insulin on insulin-like growth factor-binding protein-1 promoter activity through a conserved insulin response sequence. J Biol Chem 274:17184-17192 (Pubitemid 129519053)
-
(1999)
Journal of Biological Chemistry
, vol.274
, Issue.24
, pp. 17184-17192
-
-
Guo, S.1
Rena, G.2
Cichy, S.3
He, X.4
Cohen, P.5
Unterman, T.6
-
21
-
-
0033546439
-
Phosphorylation of the transcription factor forkhead family member FKHR by protein kinase B
-
Rena G, Guo S, Cichy SC, Unterman TG, Cohen P 1999 Phosphorylation of the transcription factor forkhead family member FKHR by protein kinase B. J Biol Chem 274:17179-17183 (Pubitemid 129519052)
-
(1999)
Journal of Biological Chemistry
, vol.274
, Issue.24
, pp. 17179-17183
-
-
Rena, G.1
Guo, S.2
Cichy, S.C.3
Unterman, T.G.4
Cohen, P.5
-
22
-
-
0035797921
-
Insulin regulation of gene expression through the forkhead transcription factor foxol (Fkhr) requires kinases distinct from Akt
-
DOI 10.1021/bi015532m
-
Nakae J, Kitamura T, Ogawa W, Kasuga M, Accili D 2001 Insulin regulation of gene expression through the forkhead transcription factor Foxo1 (Fkhr) requires kinases distinct from Akt. Biochemistry 40:11768-11776 (Pubitemid 32906038)
-
(2001)
Biochemistry
, vol.40
, Issue.39
, pp. 11768-11776
-
-
Nakae, J.1
Kitamura, T.2
Ogawa, W.3
Kasuga, M.4
Accili, D.5
-
23
-
-
11144357516
-
Role of STAT-3 in regulation of hepatic gluconeogenic genes and carbohydrate metabolism in vivo
-
DOI 10.1038/nm980
-
Inoue H, Ogawa W, Ozaki M, Haga S, Matsumoto M, Furukawa K, Hashimoto N, Kido Y, Mori T, Sakaue H, Teshigawara K, Jin S, Iguchi H, Hiramatsu R, LeRoith D, Takeda K, Akira S, Kasuga M 2004 Role of STAT-3 in regulation of hepatic gluconeogenic genes and carbohydrate metabolism in vivo. Nat Med 10:168-174 (Pubitemid 38524887)
-
(2004)
Nature Medicine
, vol.10
, Issue.2
, pp. 168-174
-
-
Inoue, H.1
Ogawa, W.2
Ozaki, M.3
Haga, S.4
Matsumoto, M.5
Furukawa, K.6
Hashimoto, N.7
Kido, Y.8
Mori, T.9
Sakaue, H.10
Teshigawara, K.11
Jin, S.12
Iguchi, H.13
Hiramatsu, R.14
Leroith, D.15
Takeda, K.16
Akira, S.17
Kasuga, M.18
-
24
-
-
33645579324
-
Role of hepatic STAT3 in brain-insulin action on hepatic glucose production
-
Inoue H, Ogawa W, Asakawa A, Okamoto Y, Nishizawa A, Matsumoto M, Teshigawara K, Matsuki Y, Watanabe E, Hiramatsu R, Notohara K, Katayose K, Okamura H, Kahn CR, Noda T, Takeda K, Akira S, Inui A, Kasuga M 2006 Role of hepatic STAT3 in brain-insulin action on hepatic glucose production. Cell Metab 3:267-275
-
(2006)
Cell Metab
, vol.3
, pp. 267-275
-
-
Inoue, H.1
Ogawa, W.2
Asakawa, A.3
Okamoto, Y.4
Nishizawa, A.5
Matsumoto, M.6
Teshigawara, K.7
Matsuki, Y.8
Watanabe, E.9
Hiramatsu, R.10
Notohara, K.11
Katayose, K.12
Okamura, H.13
Kahn, C.R.14
Noda, T.15
Takeda, K.16
Akira, S.17
Inui, A.18
Kasuga, M.19
-
25
-
-
0029666298
-
STAT3β, a splice variant of transcription factor STAT3, is a dominant negative regulator of transcription
-
Caldenhoven E, van Dijk TB, Solari R, Armstrong J, Raaijmakers JA, Lammers JW, Koenderman L, de Groot RP 1996 STAT3β, a splice variant of transcription factor STAT3, is a dominant negative regulator of transcription. J Biol Chem 271:13221-13227 (Pubitemid 26175904)
-
(1996)
Journal of Biological Chemistry
, vol.271
, Issue.22
, pp. 13221-13227
-
-
Caldenhoven, E.1
Van Dijk, T.B.2
Solari, R.3
Armstrong, J.4
Raaijmakers, J.A.M.5
Lammers, J.-W.J.6
Koenderman, L.7
De Groot, R.P.8
-
26
-
-
4644261307
-
The STAT3 isoforms α and β have unique and specific functions
-
DOI 10.1038/ni1052
-
Maritano D, Sugrue ML, Tininini S, Dewilde S, Strobl B, Fu X, Murray-Tait V, Chiarle R, Poli V 2004 The STAT3 isoforms α and β have unique and specific functions. Nat Immunol 5:401-409 (Pubitemid 38500089)
-
(2004)
Nature Immunology
, vol.5
, Issue.4
, pp. 401-409
-
-
Maritano, D.1
Sugrue, M.L.2
Tininini, S.3
Dewilde, S.4
Strobl, B.5
Fu, X.P.6
Murray-Tait, V.7
Chiarle, R.8
Poli, V.9
-
27
-
-
0036008472
-
Specific ablation of Stat3β distorts the pattern of stat3-responsive gene expression and impairs recovery from endotoxic shock
-
DOI 10.1016/S0092-8674(02)00636-0
-
Yoo JY, Huso DL, Nathans D, Desiderio S 2002 Specific ablation of Stat3β distorts the pattern of Stat3-responsive gene expression and impairs recovery from endotoxic shock. Cell 108:331-344 (Pubitemid 34178398)
-
(2002)
Cell
, vol.108
, Issue.3
, pp. 331-344
-
-
Yoo, J.-Y.1
Huso, D.L.2
Nathans, D.3
Desiderio, S.4
-
28
-
-
2042506366
-
Leptin signaling targets the thyrotropin-releasing hormone gene promoter in vivo
-
DOI 10.1210/en.2003-1312
-
Guo F, Bakal K, Minokoshi Y, Hollenberg AN 2004 Leptin signaling targets the thyrotropin-releasing hormone gene promoter in vivo. Endocrinology 145:2221-2227 (Pubitemid 38535051)
-
(2004)
Endocrinology
, vol.145
, Issue.5
, pp. 2221-2227
-
-
Guo, F.1
Bakal, K.2
Minokoshi, Y.3
Hollenberg, A.N.4
-
29
-
-
33644873467
-
Two-step cross-linking method for identification of NF-κB gene network by chromatin immunoprecipitation
-
Nowak DE, Tian B, Brasier AR 2005 Two-step cross-linking method for identification of NF-κB gene network by chromatin immunoprecipitation. Biotechniques 39:715-725
-
(2005)
Biotechniques
, vol.39
, pp. 715-725
-
-
Nowak, D.E.1
Tian, B.2
Brasier, A.R.3
-
30
-
-
23844503025
-
Role of Stat3 in regulating p53 expression and function
-
DOI 10.1128/MCB.25.17.7432-7440.2005
-
Niu G, Wright KL, Ma Y, Wright GM, Huang M, Irby R, Briggs J, Karras J, Cress WD, Pardoll D, Jove R, Chen J, Yu H 2005 Role of Stat3 in regulating p53 expression and function. Mol Cell Biol 25:7432-7440 (Pubitemid 41170107)
-
(2005)
Molecular and Cellular Biology
, vol.25
, Issue.17
, pp. 7432-7440
-
-
Niu, G.1
Wright, K.L.2
Ma, Y.3
Wright, G.M.4
Huang, M.5
Irby, R.6
Briggs, J.7
Karras, J.8
Cress, W.D.9
Pardoll, D.10
Jove, R.11
Chen, J.12
Yu, H.13
-
31
-
-
33749560285
-
Stat3 mediates interelukin-6 inhibition of human endothelial nitric-oxide synthase expression
-
DOI 10.1074/jbc.M606279200
-
Saura M, Zaragoza C, Bao C, Herranz B, Rodriguez-Puyol M, Lowenstein CJ 2006 Stat3 mediates interleukin-6 [correction of interelukin-6] inhibition of human endothelial nitric-oxide synthase expression. J Biol Chem 281:30057-30062 (Pubitemid 44537013)
-
(2006)
Journal of Biological Chemistry
, vol.281
, Issue.40
, pp. 30057-30062
-
-
Saura, M.1
Zaragoza, C.2
Bao, C.3
Herranz, B.4
Rodriguez-Puyol, M.5
Lowenstein, C.J.6
-
32
-
-
23044468612
-
Interleukin-6 depletion selectively improves hepatic insulin action in obesity
-
DOI 10.1210/en.2004-1468
-
Klover PJ, Clementi AH, Mooney RA 2005 Interleukin-6 depletion selectively improves hepatic insulin action in obesity. Endocrinology 146:3417-3427 (Pubitemid 41058114)
-
(2005)
Endocrinology
, vol.146
, Issue.8
, pp. 3417-3427
-
-
Klover, P.J.1
Clementi, A.H.2
Mooney, R.A.3
-
33
-
-
0242268894
-
Chronic Exposure to Interleukin-6 Causes Hepatic Insulin Resistance in Mice
-
DOI 10.2337/diabetes.52.11.2784
-
Klover PJ, Zimmers TA, Koniaris LG, Mooney RA 2003 Chronic exposure to interleukin-6 causes hepatic insulin resistance in mice. Diabetes 52:2784-2789 (Pubitemid 37339708)
-
(2003)
Diabetes
, vol.52
, Issue.11
, pp. 2784-2789
-
-
Klover, P.J.1
Zimmers, T.A.2
Koniaris, L.G.3
Mooney, R.A.4
-
34
-
-
0036152683
-
Interleukin-6-deficient mice develop mature-onset obesity
-
DOI 10.1038/nm0102-75
-
Wallenius V, Wallenius K, Ahrén B, Rudling M, Carlsten H, Dickson SL, Ohlsson C, Jansson JO 2002 Interleukin-6-deficient mice develop mature-onset obesity. Nat Med 8:75-79 (Pubitemid 34101732)
-
(2002)
Nature Medicine
, vol.8
, Issue.1
, pp. 75-79
-
-
Wallenius, V.1
Wallenius, K.2
Ahren, B.3
Rudling, M.4
Carlsten, H.5
Dickson, S.L.6
Ohlsson, C.7
Jansson, J.-O.8
-
35
-
-
0024380087
-
Rapid detection of octamer binding proteins with 'mini-extracts', prepared from a small number of cells
-
Schreiber E, Matthias P, Müller MM, Schaffner W 1989 Rapid detection of octamer binding proteins with 'mini-extracts', prepared from a small number of cells. Nucleic Acids Res 17:6419
-
(1989)
Nucleic Acids Res
, vol.17
, pp. 6419
-
-
Schreiber, E.1
Matthias, P.2
Müller, M.M.3
Schaffner, W.4
|