-
1
-
-
0034077041
-
Mice lacking α-synuclein display functional deficits in the nigrostriatal dopamine system
-
Abeliovich A, Schmitz Y, Farinas I, Choi-Lundberg D, Ho WH, Castillo PE et al (2000) Mice lacking alpha-synuclein display functional deficits in the nigrostriatal dopamine system. Neuron 25(1):239-252 (Pubitemid 30316525)
-
(2000)
Neuron
, vol.25
, Issue.1
, pp. 239-252
-
-
Abeliovich, A.1
Schmitz, Y.2
Farinas, I.3
Choi-Lundberg, D.4
Ho, W.-H.5
Castillo, P.E.6
Shinsky, N.7
Garcia Verdugo, J.M.8
Armanini, M.9
Ryan, A.10
Hynes, M.11
Phillips, H.12
Sulzer, D.13
Rosenthal, A.14
-
2
-
-
84886777042
-
Site-specific differences in proteasome-dependent degradation of monoubiquitinated α-synuclein
-
10.1016/j.chembiol.2013.09.009 10.1016/j.chembiol.2013.09.009
-
Abeywardana T, Lin YH, Rott R, Engelender S, Pratt MR (2013) Site-specific differences in proteasome-dependent degradation of monoubiquitinated α-synuclein. Chem Biol 20(10):1207-1213. doi: 10.1016/j.chembiol.2013.09.009
-
(2013)
Chem Biol
, vol.20
, Issue.10
, pp. 1207-1213
-
-
Abeywardana, T.1
Lin, Y.H.2
Rott, R.3
Engelender, S.4
Pratt, M.R.5
-
3
-
-
0034640160
-
α-Synuclein and the Parkinson's disease-related mutant Ala53Thr-α- synuclein do not undergo proteasomal degradation in HEK293 and neuronal cells
-
DOI 10.1016/S0304-3940(00)01049-1, PII S0304394000010491
-
Ancolio K, Alves da Costa C, Ueda K, Checler F (2000) Alpha-synuclein and the Parkinson's disease-related mutant Ala53Thr- alpha-synuclein do not undergo proteasomal degradation in HEK293 and neuronal cells. Neurosci Lett 285(2):79-82 (Pubitemid 30227624)
-
(2000)
Neuroscience Letters
, vol.285
, Issue.2
, pp. 79-82
-
-
Ancolio, K.1
Alves Da Costa, C.2
Ueda, K.3
Checler, F.4
-
4
-
-
80052398365
-
[agr]-Synuclein occurs physiologically as a helically folded tetramer that resists aggregation
-
10.1038/nature10324 10.1038/nature10324 http://www.nature.com/nature/ journal/v477/n7362/abs/nature10324.html#supplementary-information
-
Bartels T, Choi JG, Selkoe DJ (2011) [agr]-Synuclein occurs physiologically as a helically folded tetramer that resists aggregation. Nature 477(7362):107-110. doi: 10.1038/nature10324, http://www.nature.com/nature/ journal/v477/n7362/abs/nature10324.html#supplementary-information
-
(2011)
Nature
, vol.477
, Issue.7362
, pp. 107-110
-
-
Bartels, T.1
Choi, J.G.2
Selkoe, D.J.3
-
5
-
-
4644290985
-
α-synuclein locus duplication as a cause of familial Parkinson's disease
-
DOI 10.1016/S0140-6736(04)17103-1, PII S0140673604171031
-
Chartier-Harlin MC, Kachergus J, Roumier C, Mouroux V, Douay X, Lincoln S et al (2004) Alpha-synuclein locus duplication as a cause of familial Parkinson's disease. Lancet 364(9440):1167-1169. doi: 10.1016/s0140-6736(04) 17103-1 (Pubitemid 39296604)
-
(2004)
Lancet
, vol.364
, Issue.9440
, pp. 1167-1169
-
-
Chartier-Harlin, M.-C.1
Kachergus, J.2
Roumier, C.3
Mouroux, V.4
Douay, X.5
Lincoln, S.6
Levecque, C.7
Larvor, L.8
Andrieux, J.9
Hulihan, M.10
Waucquier, N.11
Defebvre, L.12
Amouyel, P.13
Farrer, M.14
Destee, A.15
-
6
-
-
0032102455
-
The synucleins: A family of proteins involved in synaptic function, plasticity, neurodegeneration and disease
-
DOI 10.1016/S0166-2236(97)01213-7
-
Clayton DF, George JM (1998) The synucleins: a family of proteins involved in synaptic function, plasticity, neurodegeneration and disease. Trends Neurosci 21(6):249-254 (Pubitemid 28239982)
-
(1998)
Trends in Neurosciences
, vol.21
, Issue.6
, pp. 249-254
-
-
Clayton, D.F.1
George, J.M.2
-
7
-
-
84884596392
-
Alpha-Synuclein as an intrinsically disordered monomer-fact or artefact?
-
10.1111/febs.12471 10.1111/febs.12471
-
Coelho-Cerqueira E, Carmo-Goncalves P, Pinheiro AS, Cortines J, Follmer C (2013) alpha-Synuclein as an intrinsically disordered monomer-fact or artefact? FEBS J 280(19):4915-4927. doi: 10.1111/febs.12471
-
(2013)
FEBS J
, vol.280
, Issue.19
, pp. 4915-4927
-
-
Coelho-Cerqueira, E.1
Carmo-Goncalves, P.2
Pinheiro, A.S.3
Cortines, J.4
Follmer, C.5
-
8
-
-
0034646391
-
Fibrils formed in vitro from α-synuclein and two mutant forms linked to Parkinson's disease are typical amyloid
-
DOI 10.1021/bi991447r
-
Conway KA, Harper JD, Lansbury PT Jr (2000) Fibrils formed in vitro from alpha-synuclein and two mutant forms linked to Parkinson's disease are typical amyloid. Biochemistry 39(10):2552-2563 (Pubitemid 30148907)
-
(2000)
Biochemistry
, vol.39
, Issue.10
, pp. 2552-2563
-
-
Conway, K.A.1
Harper, J.D.2
Lansbury Jr., P.T.3
-
9
-
-
4344659685
-
Impaired degradation of mutant α-synuclein by chaperone-mediated autophagy
-
DOI 10.1126/science.1101738
-
Cuervo AM, Stefanis L, Fredenburg R, Lansbury PT, Sulzer D (2004) Impaired degradation of mutant α-synuclein by chaperone-mediated autophagy. Science 305(5688):1292-1295. doi: 10.1126/science.1101738 (Pubitemid 39129234)
-
(2004)
Science
, vol.305
, Issue.5688
, pp. 1292-1295
-
-
Cuervo, A.M.1
Stafanis, L.2
Fredenburg, R.3
Lansbury, P.T.4
Sulzer, D.5
-
10
-
-
0032540327
-
Stabilization of α-Synuclein secondary structure upon binding to synthetic membranes
-
DOI 10.1074/jbc.273.16.9443
-
Davidson WS, Jonas A, Clayton DF, George JM (1998) Stabilization of alpha-synuclein secondary structure upon binding to synthetic membranes. J Biol Chem 273(16):9443-9449 (Pubitemid 28183026)
-
(1998)
Journal of Biological Chemistry
, vol.273
, Issue.16
, pp. 9443-9449
-
-
Davidson, W.S.1
Jonas, A.2
Clayton, D.F.3
George, J.M.4
-
11
-
-
0034661820
-
Neuropathology of synuclein aggregates
-
10.1002/1097-4547(20000715)61:2<121: AID-JNR1>3.0.CO;2-4
-
Duda JE, Lee VM, Trojanowski JQ (2000) Neuropathology of synuclein aggregates. J Neurosci Res 61(2):121-127
-
(2000)
J Neurosci Res
, vol.61
, Issue.2
, pp. 121-127
-
-
Duda, J.E.1
Lee, V.M.2
Trojanowski, J.Q.3
-
12
-
-
0035815115
-
Conformational properties of α-synuclein in its free and lipid-associated states
-
DOI 10.1006/jmbi.2001.4538
-
Eliezer D, Kutluay E, Bussell R Jr, Browne G (2001) Conformational properties of α-synuclein in its free and lipid-associated states. J Mol Biol 307(4):1061-1073. doi: 10.1006/jmbi.2001.4538 (Pubitemid 33029953)
-
(2001)
Journal of Molecular Biology
, vol.307
, Issue.4
, pp. 1061-1073
-
-
Eliezer, D.1
Kutluay, E.2
Bussell Jr., R.3
Browne, G.4
-
13
-
-
0032952414
-
Synphilin-1 associates with α-synuclein and promotes the formation of cytosolic inclusions
-
DOI 10.1038/8820
-
Engelender S, Kaminsky Z, Guo X, Sharp AH, Amaravi RK, Kleiderlein JJ et al (1999) Synphilin-1 associates with alpha-synuclein and promotes the formation of cytosolic inclusions. Nat Genet 22(1):110-114 (Pubitemid 29214817)
-
(1999)
Nature Genetics
, vol.22
, Issue.1
, pp. 110-114
-
-
Engelender, S.1
Kaminsky, Z.2
Xin, G.3
Sharp, A.H.4
Amaravi, R.K.5
Kleiderlein, J.J.6
Margolis, R.L.7
Troncoso, J.C.8
Lanahan, A.A.9
Worley, P.F.10
Dawson, V.L.11
Dawson, T.M.12
Ross, C.A.13
-
14
-
-
0029936331
-
Regulation of phosphoinositide phospholipases by hormones, neurotransmitters, and other agonists linked to G proteins
-
Exton JH (1996) Regulation of phosphoinositide phospholipases by hormones, neurotransmitters, and other agonists linked to G proteins. Annu Rev Pharmacol Toxicol 36:481-509 (Pubitemid 26168707)
-
(1996)
Annual Review of Pharmacology and Toxicology
, vol.36
, pp. 481-509
-
-
Exton, J.H.1
-
15
-
-
0036150971
-
The synucleins
-
George JM (2002) The synucleins. Genome Biol 3:3002.3001-3002.3006
-
(2002)
Genome Biol
, vol.3
, pp. 30023001-30023006
-
-
George, J.M.1
-
16
-
-
0029127954
-
Characterization of a novel protein regulated during the critical period for song learning in the zebra finch
-
10.1016/0896-6273(95)90040-3
-
George JM, Jin H, Woods WS, Clayton DF (1995) Characterization of a novel protein regulated during the critical period for song learning in the zebra finch. Neuron 15(2):361-372
-
(1995)
Neuron
, vol.15
, Issue.2
, pp. 361-372
-
-
George, J.M.1
Jin, H.2
Woods, W.S.3
Clayton, D.F.4
-
17
-
-
0033788434
-
Rat alpha-synuclein interacts with tat binding protein 1, a component of the 26S proteasomal complex [In Process Citation]
-
10.1046/j.1471-4159.2000.0752221.x
-
Ghee M, Fournier A, Mallet J (2000) Rat alpha-synuclein interacts with tat binding protein 1, a component of the 26S proteasomal complex [In Process Citation]. J Neurochem 75(5):2221-2224
-
(2000)
J Neurochem
, vol.75
, Issue.5
, pp. 2221-2224
-
-
Ghee, M.1
Fournier, A.2
Mallet, J.3
-
18
-
-
33947280424
-
α-Synuclein gene ablation increases docosahexaenoic acid incorporation and turnover in brain phospholipids
-
DOI 10.1111/j.1471-4159.2006.04357.x
-
Golovko MY, Rosenberger TA, Feddersen S, Færgeman NJ, Murphy EJ (2007) α-Synuclein gene ablation increases docosahexaenoic acid incorporation and turnover in brain phospholipids. J Neurochem 101(1):201-211. doi: 10.1111/j.1471-4159.2006.04357.x (Pubitemid 46426477)
-
(2007)
Journal of Neurochemistry
, vol.101
, Issue.1
, pp. 201-211
-
-
Golovko, M.Y.1
Rosenberger, T.A.2
Feddersen, S.3
Faergeman, N.J.4
Murphy, E.J.5
-
19
-
-
84875752373
-
Raised calcium and oxidative stress cooperatively promote alpha-synuclein aggregate formation
-
10.1016/j.neuint.2012.11.004 10.1016/j.neuint.2012.11.004
-
Goodwin J, Nath S, Engelborghs Y, Pountney DL (2013) Raised calcium and oxidative stress cooperatively promote alpha-synuclein aggregate formation. Neurochem Int 62(5):703-711. doi: 10.1016/j.neuint.2012.11.004
-
(2013)
Neurochem Int
, vol.62
, Issue.5
, pp. 703-711
-
-
Goodwin, J.1
Nath, S.2
Engelborghs, Y.3
Pountney, D.L.4
-
20
-
-
84878642954
-
A loss in cellular protein partners promotes α-synuclein aggregation in cells resulting from oxidative stress
-
10.1021/bi4002425 10.1021/bi4002425
-
Guo Y, Scarlata S (2013) A loss in cellular protein partners promotes α-synuclein aggregation in cells resulting from oxidative stress. Biochemistry 52(22):3913-3920. doi: 10.1021/bi4002425
-
(2013)
Biochemistry
, vol.52
, Issue.22
, pp. 3913-3920
-
-
Guo, Y.1
Scarlata, S.2
-
21
-
-
84862808235
-
α-Synuclein increases the cellular level of phospholipase Cβ1
-
10.1016/j.cellsig.2012.01.007 10.1016/j.cellsig.2012.01.007
-
Guo Y, Rosati B, Scarlata S (2012) α-Synuclein increases the cellular level of phospholipase Cβ1. Cell Signal 24(5):1109-1114. doi: 10.1016/j.cellsig.2012.01.007
-
(2012)
Cell Signal
, vol.24
, Issue.5
, pp. 1109-1114
-
-
Guo, Y.1
Rosati, B.2
Scarlata, S.3
-
22
-
-
33745013111
-
Oxidative stress and neurodegeneration: Where are we now?
-
DOI 10.1111/j.1471-4159.2006.03907.x
-
Halliwell B (2006) Oxidative stress and neurodegeneration: where are we now? J Neurochem 97(6):1634-1658. doi: 10.1111/j.1471-4159.2006.03907.x (Pubitemid 43873658)
-
(2006)
Journal of Neurochemistry
, vol.97
, Issue.6
, pp. 1634-1658
-
-
Halliwell, B.1
-
23
-
-
0032879452
-
Role of cytochrome c as a stimulator of α-synuclein aggregation in Lewy body disease
-
DOI 10.1074/jbc.274.41.28849
-
Hashimoto M, Takeda A, Hsu LJ, Takenouchi T, Masliah E (1999) Role of cytochrome c as a stimulator of alpha-synuclein aggregation in Lewy body disease. J Biol Chem 274(41):28849-28852 (Pubitemid 29477034)
-
(1999)
Journal of Biological Chemistry
, vol.274
, Issue.41
, pp. 28849-28852
-
-
Hashimoto, M.1
Takeda, A.2
Hsu, L.J.3
Takenouchi, T.4
Masliah, E.5
-
25
-
-
0033890821
-
α-synuclein promotes mitochondrial deficit and oxidative stress
-
Hsu LJ, Sagara Y, Arroyo A, Rockenstein E, Sisk A, Mallory M et al (2000) α-Synuclein promotes mitochondrial deficit and oxidative stress. Am J Pathol 157(2):401-410 (Pubitemid 30627559)
-
(2000)
American Journal of Pathology
, vol.157
, Issue.2
, pp. 401-410
-
-
Hsu, L.J.1
Sagara, Y.2
Arroyo, A.3
Rockenstein, E.4
Sisk, A.5
Mallory, M.6
Wong, J.7
Takenouchi, T.8
Hashimoto, M.9
Masliah, E.10
-
26
-
-
0035076647
-
α-Synuclein forms a complex with transcription factor Elk-1
-
DOI 10.1046/j.1471-4159.2001.00232.x
-
Iwata A, Miura S, Kanazawa I, Sawada M, Nukina N (2001) a-Synuclein forms a complex with transcription factor Elk-1. J Neurochem 77:239-252 (Pubitemid 32245098)
-
(2001)
Journal of Neurochemistry
, vol.77
, Issue.1
, pp. 239-252
-
-
Iwata, A.1
Miura, S.2
Kanazawa, I.3
Sawada, M.4
Nukina, N.5
-
27
-
-
0028277520
-
Identification of two distinct synucleins from human brain
-
DOI 10.1016/0014-5793(94)00395-5
-
Jakes R, Spillantini MG, Goedert M (1994) Identification of two distinct synucleins from human brain. FEBS Lett 345(1):27-32 (Pubitemid 24154659)
-
(1994)
FEBS Letters
, vol.345
, Issue.1
, pp. 27-32
-
-
Jakes, R.1
Spillantini, M.G.2
Goedert, M.3
-
28
-
-
0032492689
-
Regulation of phospholipase D2: Selective inhibition of mammalian phospholipase D isoenzymes by α- and β-synucleins
-
DOI 10.1021/bi972776r
-
Jenco JM, Rawlingson A, Daniels B, Morris AJ (1998) Regulation of phospholipase D2: selective inhibition of mammalian phospholipase D isoenzymes by alpha- and beta-synucleins. Biochemistry 37(14):4901-4909 (Pubitemid 28175972)
-
(1998)
Biochemistry
, vol.37
, Issue.14
, pp. 4901-4909
-
-
Jenco, J.M.1
Rawlingson, A.2
Daniels, B.3
Morris, A.J.4
-
29
-
-
34249704608
-
Identification of novel proteins associated with both α-synuclein and DJ-1
-
DOI 10.1074/mcp.M600182-MCP200
-
Jin J, Li GJ, Davis J, Zhu D, Wang Y, Pan C et al (2007) Identification of novel proteins associated with both alpha-synuclein and DJ-1. Mol Cell Proteomics 6(5):845-859. doi: 10.1074/mcp.M600182-MCP200 (Pubitemid 46831936)
-
(2007)
Molecular and Cellular Proteomics
, vol.6
, Issue.5
, pp. 845-859
-
-
Jin, J.1
Li, G.J.2
Davis, J.3
Zhu, D.4
Wang, Y.5
Pan, C.6
Zhang, J.7
-
30
-
-
0035066885
-
Direct binding and functional coupling of α-synuclein to the dopamine transporters accelerate dopamine-induced apoptosis
-
DOI 10.1096/fj.00-0334com
-
Lee FJ et al (2001) Direct binding and functional coupling of alpha-synuclein to the dopamine transporters accelerate dopamine-induced apoptosis. FASEB J 15:916-926 (Pubitemid 32290778)
-
(2001)
FASEB Journal
, vol.15
, Issue.6
, pp. 916-926
-
-
Lee, F.J.S.1
Liu, F.2
Pristupa, Z.B.3
Niznik, H.B.4
-
31
-
-
0037016741
-
Membrane-bound α-synuclein has a high aggregation propensity and the ability to seed the aggregation of the cytosolic form
-
DOI 10.1074/jbc.M107045200
-
Lee HJ, Choi C, Lee SJ (2002) Membrane-bound alpha-synuclein has a high aggregation propensity and the ability to seed the aggregation of the cytosolic form. J Biol Chem 277:671-678 (Pubitemid 34952106)
-
(2002)
Journal of Biological Chemistry
, vol.277
, Issue.1
, pp. 671-678
-
-
Lee, H.-J.1
Choi, C.2
Lee, S.-J.3
-
32
-
-
0035958973
-
Muscarinic Receptor Stimulation Induces Translocation of an α-Synuclein Oligomer from Plasma Membrane to a Light Vesicle Fraction in Cytoplasm
-
DOI 10.1074/jbc.M011121200
-
Leng Y, Chase TN, Bennett MC (2001) Muscarininc receptor stimulation induces translocation of an alpha-synuclein oligomer from plasma membrane to a light vesicles fraction in cytoplasm. J Biol Chem 276:28212-28218 (Pubitemid 37391526)
-
(2001)
Journal of Biological Chemistry
, vol.276
, Issue.30
, pp. 28212-28218
-
-
Leng, Y.1
Chase, T.N.2
Bennett, M.C.3
-
33
-
-
79951580982
-
Chaperone-mediated autophagy: Machinery, regulation and biological consequences
-
10.1007/s00018-010-0565-6
-
Li W, Yang Q, Mao Z (2011) Chaperone-mediated autophagy: machinery, regulation and biological consequences. Cell Mol Life Sci 68(5):749-763
-
(2011)
Cell Mol Life Sci
, vol.68
, Issue.5
, pp. 749-763
-
-
Li, W.1
Yang, Q.2
Mao, Z.3
-
34
-
-
0036797552
-
Impaired dopamine storage resulting from α-synuclein mutations may contribute to the pathogenesis of Parkinson's disease
-
Lotharius J, Brundin P (2002) Impaired dopamine storage resulting from alpha-synuclein mutation may contribute to the pathogensis of Parkinson's disease. Hum Mol Genet 11:2395-2407 (Pubitemid 35174703)
-
(2002)
Human Molecular Genetics
, vol.11
, Issue.20
, pp. 2395-2407
-
-
Lotharius, J.1
Brundin, P.2
-
35
-
-
15544371311
-
Pathogenic effects of α-synuclein aggregation
-
DOI 10.1016/j.molbrainres.2004.09.001
-
Lundvig D, Lindersson E, Jensen PH (2005) Pathogenic effects of α-synuclein aggregation. Mol Brain Res 134(1):3-17. doi: 10.1016/j.molbrainres.2004.09.001 (Pubitemid 40403636)
-
(2005)
Molecular Brain Research
, vol.134
, Issue.1
, pp. 3-17
-
-
Lundvig, D.1
Lindersson, E.2
Jensen, P.H.3
-
36
-
-
77958455514
-
Effects of curvature and composition on ± -synuclein binding to lipid vesicles
-
10.1016/j.bpj.2010.07.056
-
Middleton ER, Rhoades E (2010) Effects of curvature and composition on ± -synuclein binding to lipid vesicles. Biophys J 99(7):2279-2288
-
(2010)
Biophys J
, vol.99
, Issue.7
, pp. 2279-2288
-
-
Middleton, E.R.1
Rhoades, E.2
-
37
-
-
43749094765
-
Review. Progress in the pathogenesis and genetics of Parkinson's disease
-
DOI 10.1098/rstb.2008.2273, PII T10566MX43635557
-
Mizuno Y, Hattori N, Kubo S-I, Sato S, Nishioka K, Hatano T et al (2008) Progress in the pathogenesis and genetics of Parkinson's disease. Phil Trans R Soc B Biol Sci 363(1500):2215-2227. doi: 10.1098/rstb.2008.2273 (Pubitemid 351693531)
-
(2008)
Philosophical Transactions of the Royal Society B: Biological Sciences
, vol.363
, Issue.1500
, pp. 2215-2227
-
-
Mizuno, Y.1
Hattori, N.2
Kubo, S.-I.3
Sato, S.4
Nishioka, K.5
Hatano, T.6
Tomiyama, H.7
Funayama, M.8
Machida, Y.9
Mochizuki, H.10
-
38
-
-
0034193399
-
Synucleins are developmentally expressed, and α-synuclein regulates the size of the presynaptic vesicular pool in primary hippocampal neurons
-
Murphy DD, Rueter SM, Trojanowski JQ, Lee VM (2000) Synucleins are developmentally expressed, and alpha-synuclein regulates the size of the presynaptic vesicular pool in primary hippocampal neurons. J Neurosci 20(9):3214-3220 (Pubitemid 30263139)
-
(2000)
Journal of Neuroscience
, vol.20
, Issue.9
, pp. 3214-3220
-
-
Murphy, D.D.1
Rueter, S.M.2
Trojanowski, J.Q.3
Lee, V.M.-Y.4
-
39
-
-
0035928748
-
Membrane binding and self-association of α-synucleins
-
DOI 10.1021/bi002952n
-
Narayanan V, Scarlata S (2001) Membrane binding and self-association of alpha-synuclein. Biochemistry 40:9927-9934 (Pubitemid 32769542)
-
(2001)
Biochemistry
, vol.40
, Issue.33
, pp. 9927-9934
-
-
Narayanan, V.1
Scarlata, S.2
-
40
-
-
12144267004
-
Fluorescence studies suggest a role for α-synuclein in the phosphatidylinositol lipid signaling pathway
-
DOI 10.1021/bi0487140
-
Narayanan V, Guo Y, Scarlata S (2005) Fluorescence studies suggest a role for a-synuclein in the phosphatdiylinositol lipid signaling pathway. Biochemistry 44:462-470 (Pubitemid 40105476)
-
(2005)
Biochemistry
, vol.44
, Issue.2
, pp. 462-470
-
-
Narayanan, V.1
Guo, Y.2
Scarlata, S.3
-
41
-
-
0033565874
-
α-Synuclein shares physical and functional homology with 14-3-3 proteins
-
Ostrerova N, Petrucelli L, Farrer M, Mehta N, Choi P, Hardy J et al (1999) a-Synuclein shares physical and functional homology with 14-3-3 proteins. J Neurosci 19(14):5782-5791 (Pubitemid 29327915)
-
(1999)
Journal of Neuroscience
, vol.19
, Issue.14
, pp. 5782-5791
-
-
Ostrerova, N.1
Petrucelli, L.2
Farrer, M.3
Mehta, N.4
Choi, P.5
Hardy, J.6
Wolozin, B.7
-
42
-
-
0031678048
-
Mutation, sequence analysis, and association studies of alpha-synuclein in Parkinson's disease
-
10.1212/WNL.51.6.1757
-
Parsian A, Racette B, Zhang ZH, Chakraverty S, Rundle M, Goate A et al (1998) Mutation, sequence analysis, and association studies of alpha-synuclein in Parkinson's disease. Neurology 51(6):1757-1759
-
(1998)
Neurology
, vol.51
, Issue.6
, pp. 1757-1759
-
-
Parsian, A.1
Racette, B.2
Zhang, Z.H.3
Chakraverty, S.4
Rundle, M.5
Goate, A.6
-
43
-
-
84870340939
-
Phospholipase Cβ1 is linked to RNA interference of specific genes through translin-associated factor X
-
10.1096/fj.12-213934 10.1096/fj.12-213934
-
Philip F, Guo Y, Aisiku O, Scarlata S (2012) Phospholipase Cβ1 is linked to RNA interference of specific genes through translin-associated factor X. FASEB J 26:4903-4913. doi: 10.1096/fj.12-213934
-
(2012)
FASEB J
, vol.26
, pp. 4903-4913
-
-
Philip, F.1
Guo, Y.2
Aisiku, O.3
Scarlata, S.4
-
44
-
-
0034714204
-
Synucleins are a novel class of substrates for G protein-coupled receptor kinases
-
10.1074/jbc.M003542200
-
Pronin AN, Morris AJ, Surguchov A, Benovic JL (2000) Synucleins are a novel class of substrates for G protein-coupled receptor kinases. J Biol Chem 275(34):26515-26522
-
(2000)
J Biol Chem
, vol.275
, Issue.34
, pp. 26515-26522
-
-
Pronin, A.N.1
Morris, A.J.2
Surguchov, A.3
Benovic, J.L.4
-
45
-
-
0033779101
-
Structure, function, and control of phosphoinositide-specific phospholipase C
-
Rebecchi MJ, Pentyala SN (2000) Structure, function, and control of phosphoinositide-specific phospholipase C. Physiol Rev 80:1291-1335
-
(2000)
Physiol Rev
, vol.80
, pp. 1291-1335
-
-
Rebecchi, M.J.1
Pentyala, S.N.2
-
46
-
-
0242300619
-
α-Synuclein Locus Triplication Causes Parkinson's Disease
-
DOI 10.1126/science.1090278
-
Singleton AB, Farrer M, Johnson J, Singleton A, Hague S, Kachergus J et al (2003) a-Synuclein locus triplication causes Parkinson's disease. Science 302:841 (Pubitemid 37339619)
-
(2003)
Science
, vol.302
, Issue.5646
, pp. 841
-
-
Singleton, A.B.1
Farrer, M.2
Johnson, J.3
Singleton, A.4
Hague, S.5
Kachergus, J.6
Hulihan, M.7
Peuralinna, T.8
Dutra, A.9
Nussbaum, R.10
Lincoln, S.11
Crawley, A.12
Hanson, M.13
Maraganore, D.14
Adler, C.15
Cookson, M.R.16
Muenter, M.17
Baptista, M.18
Miller, D.19
Blancato, J.20
Hardy, J.21
Gwinn-Hardy, K.22
more..
-
47
-
-
0035109875
-
Synuclein-1 is selectively up-regulated in response to nerve growth factor treatment in PC12 cells
-
DOI 10.1046/j.1471-4159.2001.00114.x
-
Stefanis L, Kholodilov N, Rideout HG, Burke RE, Greene LA (2001) Synuclein-1 is selectively up-regulated in response to nerve growth factor treatment in PC12 cells. J Neurochem 76:1165-1176 (Pubitemid 32167390)
-
(2001)
Journal of Neurochemistry
, vol.76
, Issue.4
, pp. 1165-1176
-
-
Stefanis, L.1
Kholodilov, N.2
Rideout, H.J.3
Burke, R.E.4
Greene, L.A.5
-
48
-
-
46249091922
-
Multiple roles of phosphoinositide-specific phospholipase C isozymes
-
Suh P, Park J, Manzoli L, Cocco L, Peak J, Katan M et al (2008) Multiple roles of phosphoinositide-specific phospholipase C isozymes. BMB Rep 41:415-434 (Pubitemid 351914885)
-
(2008)
Journal of Biochemistry and Molecular Biology
, vol.41
, Issue.6
, pp. 415-434
-
-
Suh, P.-G.1
Park, J.-I.2
Manzoli, L.3
Cocco, L.4
Peak, J.C.5
Katan, M.6
Fukami, K.7
Kataoka, T.8
Yun, S.9
Sung, H.R.10
-
49
-
-
0034326816
-
Expression of mutant alpha-synuclein causes increased susceptibility to dopamine toxicity [In Process Citation]
-
10.1093/hmg/9.18.2683
-
Tabrizi SJ, Orth M, Wilkinson JM, Taanman JW, Warner TT, Cooper JM et al (2000) Expression of mutant alpha-synuclein causes increased susceptibility to dopamine toxicity [In Process Citation]. Hum Mol Genet 9(18):2683-2689
-
(2000)
Hum Mol Genet
, vol.9
, Issue.18
, pp. 2683-2689
-
-
Tabrizi, S.J.1
Orth, M.2
Wilkinson, J.M.3
Taanman, J.W.4
Warner, T.T.5
Cooper, J.M.6
-
50
-
-
0034788964
-
14-3-3 Proteins: Key regulators of cell division, signalling and apoptosis
-
DOI 10.1002/bies.1134
-
van Hemert MJ, Steensma HY, van Heusden GPH (2001) 14-3-3 proteins: key regulators of cell division, signalling and apoptosis. BioEssays 23(10):936-946. doi: 10.1002/bies.1134 (Pubitemid 32972693)
-
(2001)
BioEssays
, vol.23
, Issue.10
, pp. 936-946
-
-
Van Hemert, M.J.1
Yde Steensma, H.2
Van Paul, G.3
-
51
-
-
84862188904
-
The role of alpha-synuclein oligomerization and aggregation in cellular and animal models of Parkinson's disease
-
10.1371/journal.pone.0038545 10.1371/journal.pone.0038545
-
Wan OW, Chung KKK (2012) The role of alpha-synuclein oligomerization and aggregation in cellular and animal models of Parkinson's disease. PLoS ONE 7(6):e38545. doi: 10.1371/journal.pone.0038545
-
(2012)
PLoS ONE
, vol.7
, Issue.6
, pp. 38545
-
-
Wan, O.W.1
Chung, K.K.K.2
-
52
-
-
80055078029
-
A soluble α-synuclein construct forms a dynamic tetramer
-
10.1073/pnas.1113260108 10.1073/pnas.1113260108
-
Wang W, Perovic I, Chittuluru J, Kaganovich A, Nguyen LTT, Liao J et al (2011) A soluble α-synuclein construct forms a dynamic tetramer. Proc Natl Acad Sci 108(43):17797-17802. doi: 10.1073/pnas.1113260108
-
(2011)
Proc Natl Acad Sci
, vol.108
, Issue.43
, pp. 17797-17802
-
-
Wang, W.1
Perovic, I.2
Chittuluru, J.3
Kaganovich, A.4
Nguyen, L.T.T.5
Liao, J.6
-
53
-
-
0029904487
-
NACP, a protein implicated in Alzheimer's disease and learning, is natively unfolded
-
DOI 10.1021/bi961799n
-
Weinreb PH, Zhen W, Poon AW, Conway KA, Lansbury PT Jr (1996) NACP, a protein implicated in Alzheimer's disease and learning, is natively unfolded. Biochemistry 35(43):13709-13715 (Pubitemid 26363912)
-
(1996)
Biochemistry
, vol.35
, Issue.43
, pp. 13709-13715
-
-
Weinreb, P.H.1
Zhen, W.2
Poon, A.W.3
Conway, K.A.4
Lansbury Jr., P.T.5
-
54
-
-
0034595728
-
Overexpression of human α-synuclein causes dopamine neuron death in rat primary culture and immortalized mesencephalon-derived cells
-
DOI 10.1016/S0006-8993(00)02215-0, PII S0006899300022150
-
Zhou W, Hurlbert MS, Schaack J, Prasad KN, Freed CR (2000) Overexpression of human alpha-synuclein causes dopamine neuron death in rat primary culture and immortalized mesencephalon-derived cells. Brain Res 866(1-2):33-43 (Pubitemid 30313005)
-
(2000)
Brain Research
, vol.866
, Issue.1-2
, pp. 33-43
-
-
Zhou, W.1
Huribert, M.S.2
Schaack, J.3
Prasad, K.N.4
Freed, C.R.5
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