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Volumn 52, Issue 22, 2013, Pages 3913-3920

A loss in cellular protein partners promotes α-synuclein aggregation in cells resulting from oxidative stress

Author keywords

[No Author keywords available]

Indexed keywords

CELLULAR LEVELS; CELLULAR PROTEINS; DOWN-REGULATION; G PROTEIN ACTIVATION; NEURODEGENERATION; NEURODEGENERATIVE; PHOSPHOLIPASE C; POTENTIAL SITES;

EID: 84878642954     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi4002425     Document Type: Article
Times cited : (15)

References (34)
  • 2
    • 15544371311 scopus 로고    scopus 로고
    • Pathogenic effects of α-synuclein aggregation
    • Lundvig, D., Lindersson, E., and Jensen, P. H. (2005) Pathogenic effects of α-synuclein aggregation Mol. Brain Res. 134, 3-17
    • (2005) Mol. Brain Res. , vol.134 , pp. 3-17
    • Lundvig, D.1    Lindersson, E.2    Jensen, P.H.3
  • 3
    • 0036150971 scopus 로고    scopus 로고
    • The synucleins
    • George, J. M. (2002) The synucleins Genome Biol. 3, 3002.3001-3002.3006
    • (2002) Genome Biol. , vol.3 , pp. 30023001-30023006
    • George, J.M.1
  • 4
    • 0035928748 scopus 로고    scopus 로고
    • Membrane binding and self-association of alpha-synuclein
    • Narayanan, V. and Scarlata, S. (2001) Membrane binding and self-association of alpha-synuclein Biochemistry 40, 9927-9934
    • (2001) Biochemistry , vol.40 , pp. 9927-9934
    • Narayanan, V.1    Scarlata, S.2
  • 5
    • 80052398365 scopus 로고    scopus 로고
    • [agr]-Synuclein occurs physiologically as a helically folded tetramer that resists aggregation
    • Bartels, T., Choi, J. G., and Selkoe, D. J. (2011) [agr]-Synuclein occurs physiologically as a helically folded tetramer that resists aggregation Nature 477, 107-110
    • (2011) Nature , vol.477 , pp. 107-110
    • Bartels, T.1    Choi, J.G.2    Selkoe, D.J.3
  • 7
    • 0034681163 scopus 로고    scopus 로고
    • Acceleration of oligomerization, not fibrillization, is a shared property of both alpha-synuclein mutations linked to early-onset Parkinson's disease: Implications for pathogenesis and therapy
    • Conway, K. A., Lee, S. J., Rochet, J. C., Ding, T. T., Williamson, R. E., and Lansbury, P. T., Jr. (2000) Acceleration of oligomerization, not fibrillization, is a shared property of both alpha-synuclein mutations linked to early-onset Parkinson's disease: implications for pathogenesis and therapy Proc. Natl. Acad. Sci. U. S. A. 97, 571-576
    • (2000) Proc. Natl. Acad. Sci. U. S. A. , vol.97 , pp. 571-576
    • Conway, K.A.1    Lee, S.J.2    Rochet, J.C.3    Ding, T.T.4    Williamson, R.E.5    Lansbury Jr., P.T.6
  • 8
    • 0031678048 scopus 로고    scopus 로고
    • Mutation, sequence analysis, and association studies of alpha-synuclein in Parkinson's disease
    • Parsian, A., Racette, B., Zhang, Z. H., Chakraverty, S., Rundle, M., Goate, A., and Perlmutter, J. S. (1998) Mutation, sequence analysis, and association studies of alpha-synuclein in Parkinson's disease Neurology 51, 1757-1759
    • (1998) Neurology , vol.51 , pp. 1757-1759
    • Parsian, A.1    Racette, B.2    Zhang, Z.H.3    Chakraverty, S.4    Rundle, M.5    Goate, A.6    Perlmutter, J.S.7
  • 9
    • 15744405993 scopus 로고    scopus 로고
    • Synuclein, dopamine and oxidative stress: Co-conspirators in Parkinson's disease?
    • Maguire-Zeiss, K. A., Short, D. W., and Federoff, H. J. (2005) Synuclein, dopamine and oxidative stress: co-conspirators in Parkinson's disease? Mol. Brain Res. 134, 18-23
    • (2005) Mol. Brain Res. , vol.134 , pp. 18-23
    • Maguire-Zeiss, K.A.1    Short, D.W.2    Federoff, H.J.3
  • 10
    • 0034602442 scopus 로고    scopus 로고
    • Oxidative damage linked to neurodegeneration by selective alpha- synuclein nitration in synucleinopathy lesions [In Process Citation]
    • Giasson, B. I., Duda, J. E., Murray, I. V., Chen, Q., Souza, J. M., Hurtig, H. I., Ischiropoulos, H., Trojanowski, J. Q., and Lee, V. M. (2000) Oxidative damage linked to neurodegeneration by selective alpha- synuclein nitration in synucleinopathy lesions [In Process Citation] Science 290, 985-989
    • (2000) Science , vol.290 , pp. 985-989
    • Giasson, B.I.1    Duda, J.E.2    Murray, I.V.3    Chen, Q.4    Souza, J.M.5    Hurtig, H.I.6    Ischiropoulos, H.7    Trojanowski, J.Q.8    Lee, V.M.9
  • 11
    • 0034674652 scopus 로고    scopus 로고
    • Dityrosine cross-linking promotes formation of stable alpha -synuclein polymers. Implication of nitrative and oxidative stress in the pathogenesis of neurodegenerative synucleinopathies
    • Souza, J. M., Giasson, B. I., Chen, Q., Lee, V. M., and Ischiropoulos, H. (2000) Dityrosine cross-linking promotes formation of stable alpha -synuclein polymers. Implication of nitrative and oxidative stress in the pathogenesis of neurodegenerative synucleinopathies J. Biol. Chem. 275, 18344-18349
    • (2000) J. Biol. Chem. , vol.275 , pp. 18344-18349
    • Souza, J.M.1    Giasson, B.I.2    Chen, Q.3    Lee, V.M.4    Ischiropoulos, H.5
  • 12
    • 0034640160 scopus 로고    scopus 로고
    • Alpha-synuclein and the Parkinson's disease-related mutant Ala53Thr- alpha-synuclein do not undergo proteasomal degradation in HEK293 and neuronal cells
    • Ancolio, K., Alves da Costa, C., Ueda, K., and Checler, F. (2000) Alpha-synuclein and the Parkinson's disease-related mutant Ala53Thr- alpha-synuclein do not undergo proteasomal degradation in HEK293 and neuronal cells Neurosci. Lett. 285, 79-82
    • (2000) Neurosci. Lett. , vol.285 , pp. 79-82
    • Ancolio, K.1    Alves Da Costa, C.2    Ueda, K.3    Checler, F.4
  • 13
    • 4344659685 scopus 로고    scopus 로고
    • Impaired Degradation of Mutant α-Synuclein by Chaperone-Mediated Autophagy
    • Cuervo, A. M., Stefanis, L., Fredenburg, R., Lansbury, P. T., and Sulzer, D. (2004) Impaired Degradation of Mutant α-Synuclein by Chaperone-Mediated Autophagy Science 305, 1292-1295
    • (2004) Science , vol.305 , pp. 1292-1295
    • Cuervo, A.M.1    Stefanis, L.2    Fredenburg, R.3    Lansbury, P.T.4    Sulzer, D.5
  • 14
    • 0035066885 scopus 로고    scopus 로고
    • Direct binding and functional coupling of alpha-synuclein to the dopamine transporters accelerate dopamine-induced apoptosis
    • Lee, F. J. and al., e. (2001) Direct binding and functional coupling of alpha-synuclein to the dopamine transporters accelerate dopamine-induced apoptosis FASEB J. 15, 916-926
    • (2001) FASEB J. , vol.15 , pp. 916-926
    • Lee, F.J.1
  • 15
    • 12144267004 scopus 로고    scopus 로고
    • Fluorescence studies suggest a role for a-synuclein in the phosphatdiylinositol lipid signaling pathway
    • Narayanan, V., Guo, Y., and Scarlata, S. (2005) Fluorescence studies suggest a role for a-synuclein in the phosphatdiylinositol lipid signaling pathway Biochemistry 44, 462-470
    • (2005) Biochemistry , vol.44 , pp. 462-470
    • Narayanan, V.1    Guo, Y.2    Scarlata, S.3
  • 16
    • 84862808235 scopus 로고    scopus 로고
    • α-synuclein increases the cellular level of phospholipase Cβ1
    • Guo, Y., Rosati, B., and Scarlata, S. (2012) α-synuclein increases the cellular level of phospholipase Cβ1 Cell. Signalling 24, 1109-1114
    • (2012) Cell. Signalling , vol.24 , pp. 1109-1114
    • Guo, Y.1    Rosati, B.2    Scarlata, S.3
  • 18
    • 0033779101 scopus 로고    scopus 로고
    • Structure, function and control of phosphoinositide-specific phospholipase C
    • Rebecchi, M. and Pentylana, S. (2000) Structure, function and control of phosphoinositide-specific phospholipase C Phys. Rev. 80, 1291-1335
    • (2000) Phys. Rev. , vol.80 , pp. 1291-1335
    • Rebecchi, M.1    Pentylana, S.2
  • 19
    • 84870340939 scopus 로고    scopus 로고
    • Phospholipase Cβ1 is linked to RNA interference of specific genes through translin-associated factor X
    • Philip, F., Guo, Y., Aisiku, O., and Scarlata, S. (2012) Phospholipase Cβ1 is linked to RNA interference of specific genes through translin-associated factor X FASEB J. 26, 4903-13
    • (2012) FASEB J. , vol.26 , pp. 4903-13
    • Philip, F.1    Guo, Y.2    Aisiku, O.3    Scarlata, S.4
  • 20
    • 0033514304 scopus 로고    scopus 로고
    • Determination of the affinities between heterotrimeric G protein subunits and their phospholipase C- b effectors
    • Runnels, L. W. and Scarlata, S. (1999) Determination of the affinities between heterotrimeric G protein subunits and their phospholipase C- b effectors Biochemistry 38, 1488-1496
    • (1999) Biochemistry , vol.38 , pp. 1488-1496
    • Runnels, L.W.1    Scarlata, S.2
  • 21
    • 33747668837 scopus 로고    scopus 로고
    • Stable association between G alpha(q) and phospholipase C beta 1 in living cells
    • Dowal, L., Provitera, P., and Scarlata, S. (2006) Stable association between G alpha(q) and phospholipase C beta 1 in living cells J. Biol. Chem. 281, 23999-24014
    • (2006) J. Biol. Chem. , vol.281 , pp. 23999-24014
    • Dowal, L.1    Provitera, P.2    Scarlata, S.3
  • 22
    • 79953713263 scopus 로고    scopus 로고
    • Differential Response to Morphine of the Oligomeric State of μ-Opioid in the Presence of δ-Opioid Receptors
    • Golebiewska, U., Johnston, J. M., Devi, L., Filizola, M., and Scarlata, S. (2011) Differential Response to Morphine of the Oligomeric State of μ-Opioid in the Presence of δ-Opioid Receptors Biochemistry 50, 2829-2837
    • (2011) Biochemistry , vol.50 , pp. 2829-2837
    • Golebiewska, U.1    Johnston, J.M.2    Devi, L.3    Filizola, M.4    Scarlata, S.5
  • 23
    • 0035895355 scopus 로고    scopus 로고
    • Determination of the contact energies between a regulator of G protein signaling and G protein subunits and phospholipase C beta 1
    • Dowal, L., Elliott, J., Popov, S., Wilkie, T. M., and Scarlata, S. (2001) Determination of the contact energies between a regulator of G protein signaling and G protein subunits and phospholipase C beta 1 Biochemistry 40, 414-421
    • (2001) Biochemistry , vol.40 , pp. 414-421
    • Dowal, L.1    Elliott, J.2    Popov, S.3    Wilkie, T.M.4    Scarlata, S.5
  • 27
    • 0033564726 scopus 로고    scopus 로고
    • Copper(II)-induced self-oligomerization of alpha-synuclein
    • Paik, S. R., Shin, H. J., Lee, J. H., Chang, C. S., and Kim, J. (1999) Copper(II)-induced self-oligomerization of alpha-synuclein Biochem. J. 340, 821-828
    • (1999) Biochem. J. , vol.340 , pp. 821-828
    • Paik, S.R.1    Shin, H.J.2    Lee, J.H.3    Chang, C.S.4    Kim, J.5
  • 29
    • 84860172516 scopus 로고    scopus 로고
    • N-terminal acetylation is critical for forming α-helical oligomer of α-synuclein
    • Trexler, A. J. and Rhoades, E. (2012) N-terminal acetylation is critical for forming α-helical oligomer of α-synuclein Protein Sci. 21, 601-605
    • (2012) Protein Sci. , vol.21 , pp. 601-605
    • Trexler, A.J.1    Rhoades, E.2
  • 30
    • 0034193399 scopus 로고    scopus 로고
    • Synucleins are developmentally expressed, and alpha-synuclein regulates the size of the presynaptic vesicular pool in primary hippocampal neurons
    • Murphy, D. D., Rueter, S. M., Trojanowski, J. Q., and Lee, V. M. (2000) Synucleins are developmentally expressed, and alpha-synuclein regulates the size of the presynaptic vesicular pool in primary hippocampal neurons J. Neurosci. 20, 3214-3220
    • (2000) J. Neurosci. , vol.20 , pp. 3214-3220
    • Murphy, D.D.1    Rueter, S.M.2    Trojanowski, J.Q.3    Lee, V.M.4
  • 31
    • 33947280424 scopus 로고    scopus 로고
    • α-Synuclein gene ablation increases docosahexaenoic acid incorporation and turnover in brain phospholipids
    • Golovko, M. Y., Rosenberger, T. A., Feddersen, S., Færgeman, N. J., and Murphy, E. J. (2007) α-Synuclein gene ablation increases docosahexaenoic acid incorporation and turnover in brain phospholipids J. Neurochem. 101, 201-211
    • (2007) J. Neurochem. , vol.101 , pp. 201-211
    • Golovko, M.Y.1    Rosenberger, T.A.2    Feddersen, S.3    Færgeman, N.J.4    Murphy, E.J.5
  • 33
    • 0035958973 scopus 로고    scopus 로고
    • Muscarininc receptor stimulation induces translocation of an alpha-synuclein oligomer from plasma membrane to a light vesicles fraction in cytoplasm
    • Leng, Y., Chase, T. N., and Bennett, M. C. (2001) Muscarininc receptor stimulation induces translocation of an alpha-synuclein oligomer from plasma membrane to a light vesicles fraction in cytoplasm J. Biol. Chem. 276, 28212-28218
    • (2001) J. Biol. Chem. , vol.276 , pp. 28212-28218
    • Leng, Y.1    Chase, T.N.2    Bennett, M.C.3
  • 34
    • 0034595728 scopus 로고    scopus 로고
    • Overexpression of human alpha-synuclein causes dopamine neuron death in rat primary culture and immortalized mesencephalon-derived cells
    • Zhou, W., Hurlbert, M. S., Schaack, J., Prasad, K. N., and Freed, C. R. (2000) Overexpression of human alpha-synuclein causes dopamine neuron death in rat primary culture and immortalized mesencephalon-derived cells Brain Res. 866, 33-43
    • (2000) Brain Res. , vol.866 , pp. 33-43
    • Zhou, W.1    Hurlbert, M.S.2    Schaack, J.3    Prasad, K.N.4    Freed, C.R.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.