14-3-3 Proteins: Key regulators of cell division, signalling and apoptosis

BioEssays

Volumn 23, Issue 10, 2001, Pages 936-946

  Van Hemert, Martijn J ^a,c   Yde Steensma, H ^a   Van Paul, G ^b  

^a LEIDEN UNIVERSITY   (Netherlands)

^b DELFT UNIVERSITY OF TECHNOLOGY   (Netherlands)

^c Inst of Molecular Plant Sciences   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN 14 3 3; TYROSINE 3 MONOOXYGENASE;

ANIMAL; APOPTOSIS; CELL CYCLE; CELL DIVISION; HUMAN; METABOLISM; PHYSIOLOGY; REVIEW; SIGNAL TRANSDUCTION;

14-3-3 PROTEINS; ANIMALS; APOPTOSIS; CELL CYCLE; CELL DIVISION; HUMANS; SIGNAL TRANSDUCTION; TYROSINE 3-MONOOXYGENASE;

EUKARYOTA;

EID: 0034788964     PISSN: 02659247     EISSN: None     Source Type: Journal    
DOI: 10.1002/bies.1134     Document Type: Review

References (83)

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3. Characterization of the yeast BMH1 gene encoding a putative protein homologous to mammalian protein kinase II activators and protein kinase C inhibitors
4. The Arabidopsis 14-3-3 multigene family
5. Fusicoccin, 14-3-3 proteins, and defense responses in tomato plants
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9. The structural basis for 14-3-3:phosphopeptide binding specificity
10. Serine phosphorylation of Cbl induced by phorbol ester enhances its association with 14-3-3 proteins in T cells via a novel serine-rich 14-3-3-binding motif
11. 14-3-3 Proteins associate with A20 in an isoform-specific manner and function both as chaperone and adapter molecules
12. Binding of purified 14-3-3 zeta signaling protein to discrete amino acid sequences within the cytoplasmic domain of the platelet membrane glycoprotein lb-IX-V complex
13. 14-3-3 Zeta binds a phosphorylated Raf peptide and an unphosphorylated peptide via its conserved amphipathic groove
14. Binding of 14-3-3 protein to the plasma membrane H+-ATPase AHA2 involves the three C-terminal residues Tyr(946)-Thr-Val and requires phosphorylation of Thr(947)
15. DNA damage and replication checkpoints in fission yeast require nuclear exclusion of the Cdc25 phosphatase via 14-3-3 binding
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21. 14-3-3 Proteins associate with cdc25 phosphatases
22. Nuclear localization of Cdc25 is regulated by DNA damage and a 14-3-3 protein
23. Nuclear exclusion of Cdc25 is not required for the DNA damage checkpoint in fission yeast
24. Mitotic and G2 checkpoint control: Regulation of 14-3-3 protein binding by phosphorylation of Cdc25C on serine-216
25. Conservation of the Chk1 checkpoint pathway in mammals: Linkage of DNA damage to Cdk regulation through Cdc25
26. Association of Chk1 with 14-3-3 proteins is stimulated by DNA damage
27. 14-3-3ζ protein binds to the carboxyl half of mouse Wee1 kinase
28. Binding of 14-3-3beta to the carboxyl terminus of Wee1 increases Wee1 stability, kinase activity, and G2-M cell population
29. 14-3-3 Sigma is a p53-regulated inhibitor of G2/M progression
30. Association of the cyclin-dependent kinases and 14-3-3 sigma negatively regulates cell cycle progression
31. 14-3-3 Sigma is required to prevent mitotic catastrophe after DNA damage
32. ATM-dependent activation of p53 involves dephosphorylation and association with 14-3-3 proteins
33. The zeta isoform of 14-3-3 proteins interacts with the third intracellular loop of different alpha(2)-adrenergic receptor subtypes
34. Identification of a binding sequence for the 14-3-3 protein within the cytoplasmic domain of the adhesion receptor, platelet glycoprotein lb alpha
35. Human signaling protein 14-3-3 zeta interacts with platelet glycoprotein lb subunits lb alpha and lb beta
36. Phosphoinositide 3-kinase forms a complex with platelet membrane glycoprotein lb-IX-V complex and 14-3-3zeta
37. Site-specific serine phosphorylation of the IL-3 receptor is required for hemopoietic cell survival
38. 14-3-3Zeta interacts with the alpha-chain of human interleukin 9 receptor
39. 14-3-3 (epsilon) interacts with the insulin-like growth factor I receptor and insulin receptor substrate I in a phosphoserine-dependent manner
40. 14-3-3 Protein binds to insulin receptor substrate-1, one of the binding sites of which is in the phosphotyrosine binding domain
41. 14-3-3Beta protein associates with insulin receptor substrate 1 and decreases insulin-stimulated phosphatidylinositol 3′-kinase activity in 3T3L1 adipocytes
42. 14-3-3 Proteins interact with the insulin-like growth factor receptor but not the insulin receptor
43. Interaction of the ligand-activated glucocorticoid receptor with the 14-3-3 eta protein
44. Functional interaction of the immunosuppressant mizoribine with the 14-3-3 protein
45. Protein kinase C inhibitor proteins. Purification from sheep brain and sequence similarity to lipocortins and 14-3-3 protein
46. Activation of protein kinase C by the 14-3-3 proteins homologous with Exo1 protein that stimulates calcium-dependent exocytosis
47. Activation of protein kinase C by purified bovine brain 14-3-3: Comparison with tyrosine hydroxylase activation
48. Differential activation of PKC isozymes by 14-3-3 zeta protein
49. Protein kinase C activation by acidic proteins including 14-3-3
50. Interaction of the protein kinase Raf-1 with 14-3-3 proteins
51. Activation of Raf-1 by 14-3-3 proteins
52. Stimulatory effects of yeast and mammalian 14-3-3 proteins on the Raf protein kinase
53. Binding of 14-3-3 proteins to the protein kinase Raf and effects on its activation
54. Identification of signalling proteins interacting with B-Raf in the yeast two-hybrid system
55. Activated Ras displaces 14-3-3 protein from the amino terminus of c-Raf-1
56. Regulation of the Raf-1 kinase domain by phosphorylation and 14-3-3 association
57. BCR and RAF form a complex in vivo via 14-3-3 proteins
58. The protein kinase KSR interacts with 14-3-3 protein and Raf
59. Purification of a Ras-dependent mitogen-activated protein kinase kinase kinase from bovine brain cytosol and its identification as a complex of B-Raf and 14-3-3 proteins
60. Requirement for Drosophila 13-3-3 zeta in Raf-dependent photoreceptor development
61. Association of the protein kinases c-Bcr and Bcr-Abl with proteins of the 14-3-3 family
62. 14-3-3 Proteins interact with specific MEK kinases
63. 14-3-3 Proteins are essential for RAS/MAPK cascade signaling during pseudohyphal development in S-cerevisiae
64. Nuclear localization of protein kinase U-alpha is regulated by 14-3-3
65. The Cdk-like protein PCTAIRE-1 from mouse brain associates with p11 and 14-3-3 proteins
66. Phosphorylation-dependent association of the Ras-related GTP-binding protein Rem with 14-3-3 proteins
67. Protein binding and signaling properties of RIN1 suggest a unique effector function
68. Regulation of Cbl molecular interactions by the co-receptor molecule CD43 in human T cells
69. Cell adhesion regulates the interaction between the docking protein p130(Cas) and the 14-3-3 proteins
70. Inhibition of phosphatidylinositol 3-kinase activity by association with 14-3-3 proteins in T cells
71. Phosphoinositide-specific phospholipase C forms a complex with 14-3-3 proteins and is involved in expression of UV resistance in fission yeast
72. Activation of the 43 kDa inositol polyphosphate 5-phosphatase by 14-3-3 zeta
73. In vivo and in vitro association of 14-3-3 epsilon isoform with calmodulin: Implication for signal transduction and cell proliferation
74. Serine phosphorylation-dependent association of the band 4.1-related protein-tyrosine phosphatase PTPH1 with 14-3-3beta protein
75. 14-3-3 Proteins block apoptosis and differentially regulate MAPK cascades
76. Serine phosphorylation of death agonist BAD in response to survival factor results in binding to 14-3-3 not BCL-X(L)
77. Calcium promotes cell survival through CaM-K kinase activation of the protein-kinase-B pathway
78. Regulation of BAD by cAMP-dependent protein kinase is mediated via phosphorylation of a novel site, Ser155
79. BAD Ser-155 phosphorylation regulates BAD/Bcl-XL interaction and cell survival
80. 14-3-3 Proteins and survival kinases cooperate to inactivate BAD by BH3 domain phosphorylation
81. Ca2+-induced apoptosis through calcineurin dephosphorylation of BAD
82. Akt promotes cell survival by phosphorylating and inhibiting a forkhead transcription factor
83. Suppression of apoptosis signal-regulating kinase 1-induced cell death by 14-3-3 proteins