Quantitation of metformin in human plasma and urine by hydrophilic interaction liquid chromatography and application to a pharmacokinetic study

Therapeutic Drug Monitoring

Volumn 36, Issue 2, 2014, Pages 211-217

  Nielsen, Flemming ^a   Christensen, Mette M H ^a   Brøsen, Kim ^a  

^a UNIVERSITY OF SOUTHERN DENMARK   (Denmark)

Author keywords

Clinical pharmacokinetics; HILIC chromatography; Metformin in human plasma and urine; Solid phase extraction

Indexed keywords

METFORMIN; ANTIDIABETIC AGENT;

AREA UNDER THE CURVE; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG URINE LEVEL; HUMAN; HYDROPHILIC INTERACTION CHROMATOGRAPHY; MALE; MAXIMUM PLASMA CONCENTRATION; PRIORITY JOURNAL; REPRODUCIBILITY; SINGLE DRUG DOSE; SOLID PHASE EXTRACTION; TIME TO MAXIMUM PLASMA CONCENTRATION; BLOOD; CHEMICAL PHENOMENA; CHEMISTRY; LIMIT OF DETECTION; LIQUID CHROMATOGRAPHY; NORMAL HUMAN; PLASMA; PROCEDURES; SENSITIVITY AND SPECIFICITY; URINE; VALIDATION STUDY;

CHROMATOGRAPHY, LIQUID; HEALTHY VOLUNTEERS; HUMANS; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; HYPOGLYCEMIC AGENTS; LIMIT OF DETECTION; MALE; METFORMIN; PLASMA; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; URINE;

EID: 84897074091     PISSN: 01634356     EISSN: 15363694     Source Type: Journal    
DOI: 10.1097/FTD.0b013e3182a4598a     Document Type: Article

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