Simultaneous determination of metformin and rosiglitazone in human plasma by liquid chromatography/tandem mass spectrometry with electrospray ionization: Application to a pharmacokinetic study

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Volumn 854, Issue 1-2, 2007, Pages 91-98

  Zhang, Lu ^a   Tian, Yuan ^a   Zhang, Zunjian ^a   Chen, Yun ^b  

^a CHINA PHARMACEUTICAL UNIVERSITY   (China)

^b PEKING UNION MEDICAL COLLEGE   (China)

Author keywords

Liquid chromatography tandem mass spectrometry; Metformin; Pharmacokinetics; Quantitation; Rosiglitazone

Indexed keywords

AMMONIUM COMPOUNDS; DRUG PRODUCTS; ELECTROSPRAY IONIZATION; LIQUID CHROMATOGRAPHY; MAMMALS; MASS SPECTROMETRY; PH EFFECTS;

METFORMIN; ROSIGLITAZONE; TANDEM MASS SPECTROMETRY;

PHARMACOKINETICS;

ACETONITRILE; METFORMIN; ROSIGLITAZONE;

ACCURACY; ADULT; AREA UNDER THE CURVE; ARTICLE; BLOOD SAMPLING; CLINICAL ARTICLE; CLINICAL TRIAL; DRUG BLOOD LEVEL; DRUG DETERMINATION; DRUG HALF LIFE; ELECTROSPRAY MASS SPECTROMETRY; FEMALE; HUMAN; LIQUID CHROMATOGRAPHY; MALE; PRIORITY JOURNAL; SENSITIVITY AND SPECIFICITY; STANDARD; TANDEM MASS SPECTROMETRY;

CHROMATOGRAPHY, LIQUID; HUMANS; HYPOGLYCEMIC AGENTS; METFORMIN; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; TANDEM MASS SPECTROMETRY; THIAZOLIDINEDIONES;

EID: 34250770502     PISSN: 15700232     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jchromb.2007.04.002     Document Type: Article

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