Arginine and lysine reduce the high viscosity of serum albumin solutions for pharmaceutical injection

Journal of Bioscience and Bioengineering

Volumn 117, Issue 5, 2014, Pages 539-543

  Inoue, Naoto ^a   Takai, Eisuke ^a   Arakawa, Tsutomu ^b   Shiraki, Kentaro ^a  

^a UNIVERSITY OF TSUKUBA   (Japan)

^b ALLIANCE PROTEIN LABORATORIES   (United States)

Author keywords

Arginine; Lysine; Protein protein interaction; Serum albumin; Viscosity

Indexed keywords

ARGININE; BODY FLUIDS; FOURIER TRANSFORM INFRARED SPECTROSCOPY; PH EFFECTS; VISCOSITY;

BOVINE SERUM ALBUMINS; ELECTROSTATIC SHIELDING EFFECTS; GUANIDINE HYDROCHLORIDE; L-LYSINE HYDROCHLORIDE; LYSINE; PROTEIN CONCENTRATIONS; PROTEIN-PROTEIN INTERACTIONS; SERUM ALBUMIN;

PROTEINS;

AMINO ACID; ARGININE; BOVINE SERUM ALBUMIN; GUANIDINE; HUMAN SERUM ALBUMIN; LYSINE; SODIUM CHLORIDE;

ARTICLE; DRUG EFFECT; DRUG SOLUTION; INFRARED SPECTROSCOPY; PH; PROTEIN PROTEIN INTERACTION; STATIC ELECTRICITY; VISCOSITY;

BOVINAE;

ARGININE; LYSINE; PROTEIN-PROTEIN INTERACTION; SERUM ALBUMIN; VISCOSITY;

ANIMALS; ARGININE; CATTLE; HUMANS; HYDROGEN-ION CONCENTRATION; INJECTIONS; LYSINE; PROTEIN BINDING; SERUM ALBUMIN; SERUM ALBUMIN, BOVINE; SODIUM CHLORIDE; SOLUTIONS; STATIC ELECTRICITY; VISCOSITY;

EID: 84897069677     PISSN: 13891723     EISSN: 13474421     Source Type: Journal    
DOI: 10.1016/j.jbiosc.2013.10.016     Document Type: Article

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