Understanding and modulating opalescence and viscosity in a monoclonal antibody formulation

Journal of Pharmaceutical Sciences

Volumn 99, Issue 1, 2010, Pages 82-93

  Salinas, Branden A ^a,b   Sathish, Hasige A ^a,b,c   Bishop, Steven M ^c   Harn, Nick ^c   Carpenter, John F ^b,d   Randolph, Theodore W ^a,b  

^a University of Colorado   (United States)

^b UNIVERSITY OF COLORADO   (United States)

^c MEDIMMUNE   (United States)

^d UNIVERSITY OF COLORADO   (United States)

Author keywords

Light scattering; Physical characterization; Protein delivery; Protein formulation; Viscosity

Indexed keywords

IMMUNOGLOBULIN G1; MONOCLONAL ANTIBODY;

ARTICLE; DRUG FORMULATION; IONIC STRENGTH; LIGHT SCATTERING; MOLECULAR WEIGHT; NEPHELOMETRY; PROTEIN PROTEIN INTERACTION; TURBIDITY; VISCOSITY; ZETA POTENTIAL;

EID: 73949139940     PISSN: 00223549     EISSN: 15206017     Source Type: Journal    
DOI: 10.1002/jps.21797     Document Type: Article

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