Carboxylate-dependent gelation of a monoclonal antibody

Pharmaceutical Research

Volumn 26, Issue 11, 2009, Pages 2478-2485

  Esue, Osigwe ^a   Kanai, Sonoko ^a   Liu, Jun ^a   Patapoff, Thomas W ^a   Shire, Steven J ^a  

^a GENENTECH INC   (United States)

Author keywords

Carboxylates; Cryoglobulins; Gelation; Mechanical properties; Monoclonal antibody; Self association; Structure; Viscosity

Indexed keywords

BARIUM ION; CALCIUM ION; CARBOXYLIC ACID; CRYOGLOBULIN; MANGANESE; MONOCLONAL ANTIBODY;

ARTICLE; ELECTRON MICROSCOPY; FLOW MEASUREMENT; GEL; GELATION; INFRARED SPECTROSCOPY; IONIC STRENGTH; PRIORITY JOURNAL; PROTEIN ASSEMBLY; RAMAN SPECTROMETRY; STRUCTURE ANALYSIS; VISCOELASTICITY;

ANTIBODIES, MONOCLONAL; CARBOXYLIC ACIDS; CITRATES; ELASTICITY; GELS; HUMANS; SPECTROSCOPY, FOURIER TRANSFORM INFRARED; VISCOSITY;

EID: 70350223665     PISSN: 07248741     EISSN: 1573904X     Source Type: Journal    
DOI: 10.1007/s11095-009-9963-6     Document Type: Article

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