메뉴 건너뛰기




Volumn 14, Issue 8, 2013, Pages 777-784

Short-term memory of danger signals and environmental stimuli in immune cells

Author keywords

[No Author keywords available]

Indexed keywords

HISTONE ACETYLTRANSFERASE; HISTONE DEACETYLASE; HISTONE H3; LONG UNTRANSLATED RNA; MICRORNA; STAT1 PROTEIN; STAT4 PROTEIN;

EID: 84880815366     PISSN: 15292908     EISSN: 15292916     Source Type: Journal    
DOI: 10.1038/ni.2636     Document Type: Review
Times cited : (75)

References (131)
  • 1
    • 70349559403 scopus 로고    scopus 로고
    • Endotoxin tolerance: New mechanisms, molecules and clinical significance
    • Biswas, S.K. & Lopez-Collazo, E. Endotoxin tolerance: New mechanisms, molecules and clinical significance. Trends Immunol. 30, 475-487 (2009).
    • (2009) Trends Immunol. , vol.30 , pp. 475-487
    • Biswas, S.K.1    Lopez-Collazo, E.2
  • 2
    • 77952395705 scopus 로고    scopus 로고
    • Potent phagocytic activity with impaired antigen presentation identifying lipopolysaccharide-tolerant human monocytes: Demonstration in isolated monocytes from cystic fibrosis patients
    • del Fresno, C. et al. Potent phagocytic activity with impaired antigen presentation identifying lipopolysaccharide-tolerant human monocytes: Demonstration in isolated monocytes from cystic fibrosis patients. J. Immunol. 182, 6494-6507 (2009).
    • (2009) J. Immunol. , vol.182 , pp. 6494-6507
    • Del Fresno, C.1
  • 3
    • 47849130092 scopus 로고    scopus 로고
    • Cytomegalovirus reactivation in critically ill immunocompetent patients
    • Limaye, A.P. et al. Cytomegalovirus reactivation in critically ill immunocompetent patients. J. Am. Med. Assoc. 300, 413-422 (2008).
    • (2008) J. Am. Med. Assoc. , vol.300 , pp. 413-422
    • Limaye, A.P.1
  • 4
  • 5
    • 0032100763 scopus 로고    scopus 로고
    • Modulation of cytokine-induced HIV gene expression by competitive binding of transcription factors to the coactivator p300
    • Hottiger, M.O., Felzien, L.K. & Nabel, G.J. Modulation of cytokine-induced HIV gene expression by competitive binding of transcription factors to the coactivator p300. EMBO J. 17, 3124-3134 (1998).
    • (1998) EMBO J. , vol.17 , pp. 3124-3134
    • Hottiger, M.O.1    Felzien, L.K.2    Nabel, G.J.3
  • 6
    • 77949977555 scopus 로고    scopus 로고
    • Identification and characterization of enhancers controlling the inflammatory gene expression program in macrophages
    • Ghisletti, S. et al. Identification and characterization of enhancers controlling the inflammatory gene expression program in macrophages. Immunity 32, 317-328 (2010).
    • (2010) Immunity , vol.32 , pp. 317-328
    • Ghisletti, S.1
  • 7
    • 29144463657 scopus 로고    scopus 로고
    • Dynamic acetylation of all lysine 4-methylated histone H3 in the mouse nucleus: Analysis at c-fos and c-jun
    • Hazzalin, C.A. & Mahadevan, L.C. Dynamic acetylation of all lysine 4-methylated histone H3 in the mouse nucleus: Analysis at c-fos and c-jun. PLoS Biol. 3, e393 (2005).
    • (2005) PLoS Biol. , vol.3
    • Hazzalin, C.A.1    Mahadevan, L.C.2
  • 9
    • 78649698079 scopus 로고    scopus 로고
    • Global turnover of histone post-translational modifications and variants in human cells
    • Zee, B.M., Levin, R.S., Dimaggio, P.A. & Garcia, B.A. Global turnover of histone post-translational modifications and variants in human cells. Epigenetics Chromatin 3, 22 (2010).
    • (2010) Epigenetics Chromatin , vol.3 , Issue.22
    • Zee, B.M.1    Levin, R.S.2    Dimaggio, P.A.3    Garcia, B.A.4
  • 10
    • 77449086407 scopus 로고    scopus 로고
    • In vivo residue-specific histone methylation dynamics
    • Zee, B.M. et al. In vivo residue-specific histone methylation dynamics. J. Biol. Chem. 285, 3341-3350 (2009).
    • (2009) J. Biol. Chem. , vol.285 , pp. 3341-3350
    • Zee, B.M.1
  • 11
    • 84872522528 scopus 로고    scopus 로고
    • Latent enhancers activated by stimulation in differentiated cells
    • Ostuni, R. et al. Latent enhancers activated by stimulation in differentiated cells. Cell 152, 157-171 (2013).
    • (2013) Cell , vol.152 , pp. 157-171
    • Ostuni, R.1
  • 12
    • 84865119423 scopus 로고    scopus 로고
    • Candida albicans infection affords protection against reinfection via functional reprogramming of monocytes
    • Quintin, J. et al. Candida albicans infection affords protection against reinfection via functional reprogramming of monocytes. Cell Host Microbe 12, 223-232 (2012).
    • (2012) Cell Host Microbe , vol.12 , pp. 223-232
    • Quintin, J.1
  • 13
    • 33846019277 scopus 로고    scopus 로고
    • Methylation of lysine 4 on histone H3: Intricacy of writing and reading a single epigenetic mark
    • Ruthenburg, A.J., Allis, C.D. & Wysocka, J. Methylation of lysine 4 on histone H3: Intricacy of writing and reading a single epigenetic mark. Mol. Cell 25, 15-30 (2007).
    • (2007) Mol. Cell , vol.25 , pp. 15-30
    • Ruthenburg, A.J.1    Allis, C.D.2    Wysocka, J.3
  • 14
    • 67649648237 scopus 로고    scopus 로고
    • Control of inducible gene expression by signal-dependent transcriptional elongation
    • Hargreaves, D.C., Horng, T. & Medzhitov, R. Control of inducible gene expression by signal-dependent transcriptional elongation. Cell 138, 129-145 (2009).
    • (2009) Cell , vol.138 , pp. 129-145
    • Hargreaves, D.C.1    Horng, T.2    Medzhitov, R.3
  • 15
    • 70350754328 scopus 로고    scopus 로고
    • Jmjd3 contributes to the control of gene expression in LPS-activated macrophages
    • De Santa, F. et al. Jmjd3 contributes to the control of gene expression in LPS-activated macrophages. EMBO J. 28, 3341-3352 (2009).
    • (2009) EMBO J. , vol.28 , pp. 3341-3352
    • De Santa, F.1
  • 16
    • 73349142390 scopus 로고    scopus 로고
    • Dynamic bookmarking of primary response genes by p300 and RNA polymerase II complexes
    • Byun, J.S. et al. Dynamic bookmarking of primary response genes by p300 and RNA polymerase II complexes. Proc. Natl. Acad. Sci. USA 106, 19286-19291 (2009).
    • (2009) Proc. Natl. Acad. Sci. USA , vol.106 , pp. 19286-19291
    • Byun, J.S.1
  • 17
    • 33847334699 scopus 로고    scopus 로고
    • Distinct and predictive chromatin signatures of transcriptional promoters and enhancers in the human genome
    • Heintzman, N. et al. Distinct and predictive chromatin signatures of transcriptional promoters and enhancers in the human genome. Nat. Genet. 39, 311-318 (2007).
    • (2007) Nat. Genet. , vol.39 , pp. 311-318
    • Heintzman, N.1
  • 18
    • 79951516056 scopus 로고    scopus 로고
    • A unique chromatin signature uncovers early developmental enhancers in humans
    • Rada-Iglesias, A. et al. A unique chromatin signature uncovers early developmental enhancers in humans. Nature 470, 279-283 (2011).
    • (2011) Nature , vol.470 , pp. 279-283
    • Rada-Iglesias, A.1
  • 19
    • 60149091656 scopus 로고    scopus 로고
    • ChIP-seq accurately predicts tissue-specific activity of enhancers
    • Visel, A. et al. ChIP-seq accurately predicts tissue-specific activity of enhancers. Nature 457, 854-858 (2009).
    • (2009) Nature , vol.457 , pp. 854-858
    • Visel, A.1
  • 20
    • 38649099445 scopus 로고    scopus 로고
    • High-resolution mapping and characterization of open chromatin across the genome
    • Boyle, A.P. et al. High-resolution mapping and characterization of open chromatin across the genome. Cell 132, 311-322 (2008).
    • (2008) Cell , vol.132 , pp. 311-322
    • Boyle, A.P.1
  • 21
    • 65549104157 scopus 로고    scopus 로고
    • Histone modifications at human enhancers reflect global cell-type-specific gene expression
    • Heintzman, N.D. et al. Histone modifications at human enhancers reflect global cell-type-specific gene expression. Nature 459, 108-112 (2009).
    • (2009) Nature , vol.459 , pp. 108-112
    • Heintzman, N.D.1
  • 22
    • 84865790047 scopus 로고    scopus 로고
    • An integrated encyclopedia of DNA elements in the human genome
    • Dunham, I. et al. An integrated encyclopedia of DNA elements in the human genome. Nature 489, 57-74 (2012).
    • (2012) Nature , vol.489 , pp. 57-74
    • Dunham, I.1
  • 23
    • 84865708757 scopus 로고    scopus 로고
    • An expansive human regulatory lexicon encoded in transcription factor footprints
    • Neph, S. et al. An expansive human regulatory lexicon encoded in transcription factor footprints. Nature 489, 83-90 (2012).
    • (2012) Nature , vol.489 , pp. 83-90
    • Neph, S.1
  • 24
    • 79955583542 scopus 로고    scopus 로고
    • Mapping and analysis of chromatin state dynamics in nine human cell types
    • Ernst, J. et al. Mapping and analysis of chromatin state dynamics in nine human cell types. Nature 473, 43-49 (2011).
    • (2011) Nature , vol.473 , pp. 43-49
    • Ernst, J.1
  • 25
    • 84865755978 scopus 로고    scopus 로고
    • The accessible chromatin landscape of the human genome
    • Thurman, R.E. et al. The accessible chromatin landscape of the human genome. Nature 489, 75-82 (2012).
    • (2012) Nature , vol.489 , pp. 75-82
    • Thurman, R.E.1
  • 26
    • 77954928774 scopus 로고    scopus 로고
    • Maintaining cell identity through global control of genomic organization
    • Natoli, G. Maintaining cell identity through global control of genomic organization. Immunity 33, 12-24 (2010).
    • (2010) Immunity , vol.33 , pp. 12-24
    • Natoli, G.1
  • 27
    • 84867581744 scopus 로고    scopus 로고
    • A validated regulatory network for Th17 cell specification
    • Ciofani, M. et al. A validated regulatory network for Th17 cell specification. Cell 151, 289-303 (2012).
    • (2012) Cell , vol.151 , pp. 289-303
    • Ciofani, M.1
  • 28
    • 84866975037 scopus 로고    scopus 로고
    • Foxp3 exploits a pre-existent enhancer landscape for regulatory T cell lineage specification
    • Samstein, R.M. et al. Foxp3 exploits a pre-existent enhancer landscape for regulatory T cell lineage specification. Cell 151, 153-166 (2012).
    • (2012) Cell , vol.151 , pp. 153-166
    • Samstein, R.M.1
  • 29
    • 84870027825 scopus 로고    scopus 로고
    • STATs shape the active enhancer landscape of T cell populations
    • Vahedi, G. et al. STATs shape the active enhancer landscape of T cell populations. Cell 151, 981-993 (2012).
    • (2012) Cell , vol.151 , pp. 981-993
    • Vahedi, G.1
  • 30
    • 77952567987 scopus 로고    scopus 로고
    • Simple combinations of lineage-determining transcription factors prime cis-regulatory elements required for macrophage and B cell identities
    • Heinz, S. et al. Simple combinations of lineage-determining transcription factors prime cis-regulatory elements required for macrophage and B cell identities. Mol. Cell 38, 576-589 (2010).
    • (2010) Mol. Cell , vol.38 , pp. 576-589
    • Heinz, S.1
  • 31
    • 82955198464 scopus 로고    scopus 로고
    • Recognition of enhancer element-specific histone methylation by TIP60 in transcriptional activation
    • Jeong, K.W. et al. Recognition of enhancer element-specific histone methylation by TIP60 in transcriptional activation. Nat. Struct. Mol. Biol. 18, 1358-1365 (2011).
    • (2011) Nat. Struct. Mol. Biol. , vol.18 , pp. 1358-1365
    • Jeong, K.W.1
  • 32
    • 43249102851 scopus 로고    scopus 로고
    • Erasing the methyl mark: Histone demethylases at the center of cellular differentiation and disease
    • Cloos, P.A., Christensen, J., Agger, K. & Helin, K. Erasing the methyl mark: Histone demethylases at the center of cellular differentiation and disease. Genes Dev. 22, 1115-1140 (2008).
    • (2008) Genes Dev. , vol.22 , pp. 1115-1140
    • Cloos, P.A.1    Christensen, J.2    Agger, K.3    Helin, K.4
  • 33
    • 84872051865 scopus 로고    scopus 로고
    • Histone chaperones in nucleosome assembly and human disease
    • Burgess, R.J. & Zhang, Z. Histone chaperones in nucleosome assembly and human disease. Nat. Struct. Mol. Biol. 20, 14-22 (2013).
    • (2013) Nat. Struct. Mol. Biol. , vol.20 , pp. 14-22
    • Burgess, R.J.1    Zhang, Z.2
  • 34
    • 77952241644 scopus 로고    scopus 로고
    • New functions for an old variant: No substitute for histone H3.3
    • Elsaesser, S.J., Goldberg, A.D. & Allis, C.D. New functions for an old variant: No substitute for histone H3.3. Curr. Opin. Genet. Dev. 20, 110-117 (2010).
    • (2010) Curr. Opin. Genet. Dev. , vol.20 , pp. 110-117
    • Elsaesser, S.J.1    Goldberg, A.D.2    Allis, C.D.3
  • 35
    • 33947137710 scopus 로고    scopus 로고
    • Dynamics of replication-independent histone turnover in budding yeast
    • Dion, M.F. et al. Dynamics of replication-independent histone turnover in budding yeast. Science 315, 1405-1408 (2007).
    • (2007) Science , vol.315 , pp. 1405-1408
    • Dion, M.F.1
  • 36
    • 33847076849 scopus 로고    scopus 로고
    • Chromatin modifications and their function
    • Kouzarides, T. Chromatin modifications and their function. Cell 128, 693-705 (2007).
    • (2007) Cell , vol.128 , pp. 693-705
    • Kouzarides, T.1
  • 37
    • 80052942443 scopus 로고    scopus 로고
    • Identification of 67 histone marks and histone lysine crotonylation as a new type of histone modification
    • Tan, M. et al. Identification of 67 histone marks and histone lysine crotonylation as a new type of histone modification. Cell 146, 1016-1028 (2011).
    • (2011) Cell , vol.146 , pp. 1016-1028
    • Tan, M.1
  • 38
    • 84862908850 scopus 로고    scopus 로고
    • Extensive promoter-centered chromatin interactions provide a topological basis for transcription regulation
    • Li, G. et al. Extensive promoter-centered chromatin interactions provide a topological basis for transcription regulation. Cell 148, 84-98 (2012).
    • (2012) Cell , vol.148 , pp. 84-98
    • Li, G.1
  • 39
    • 84861964135 scopus 로고    scopus 로고
    • Controlling long-range genomic interactions at a native locus by targeted tethering of a looping factor
    • Deng, W. et al. Controlling long-range genomic interactions at a native locus by targeted tethering of a looping factor. Cell 149, 1233-1244 (2012).
    • (2012) Cell , vol.149 , pp. 1233-1244
    • Deng, W.1
  • 40
    • 0027248178 scopus 로고
    • Interaction between transcription regulatory regions of prolactin chromatin
    • Cullen, K.E., Kladde, M.P. & Seyfred, M.A. Interaction between transcription regulatory regions of prolactin chromatin. Science 261, 203-206 (1993).
    • (1993) Science , vol.261 , pp. 203-206
    • Cullen, K.E.1    Kladde, M.P.2    Seyfred, M.A.3
  • 41
    • 0037083376 scopus 로고    scopus 로고
    • Capturing chromosome conformation
    • Dekker, J., Rippe, K., Dekker, M. & Kleckner, N. Capturing chromosome conformation. Science 295, 1306-1311 (2002).
    • (2002) Science , vol.295 , pp. 1306-1311
    • Dekker, J.1    Rippe, K.2    Dekker, M.3    Kleckner, N.4
  • 42
    • 84855297335 scopus 로고    scopus 로고
    • A decade of 3C technologies: Insights into nuclear organization
    • de Wit, E. & de Laat, W. A decade of 3C technologies: Insights into nuclear organization. Genes Dev. 26, 11-24 (2012).
    • (2012) Genes Dev. , vol.26 , pp. 11-24
    • De Wit, E.1    De Laat, W.2
  • 43
    • 84877826959 scopus 로고    scopus 로고
    • Chromosomal domains: Epigenetic contexts and functional implications of genomic compartmentalization
    • Tanay, A. & Cavalli, G. Chromosomal domains: Epigenetic contexts and functional implications of genomic compartmentalization. Curr. Opin. Genet. Dev. 23, 197-203 (2013).
    • (2013) Curr. Opin. Genet. Dev. , vol.23 , pp. 197-203
    • Tanay, A.1    Cavalli, G.2
  • 44
    • 84876838711 scopus 로고    scopus 로고
    • The hierarchy of the 3D genome
    • Gibcus, J.H. & Dekker, J. The hierarchy of the 3D genome. Mol. Cell 49, 773-782 (2013).
    • (2013) Mol. Cell , vol.49 , pp. 773-782
    • Gibcus, J.H.1    Dekker, J.2
  • 45
    • 84861095603 scopus 로고    scopus 로고
    • Topological domains in mammalian genomes identified by analysis of chromatin interactions
    • Dixon, J.R. et al. Topological domains in mammalian genomes identified by analysis of chromatin interactions. Nature 485, 376-380 (2012).
    • (2012) Nature , vol.485 , pp. 376-380
    • Dixon, J.R.1
  • 46
    • 84861100147 scopus 로고    scopus 로고
    • Spatial partitioning of the regulatory landscape of the X-inactivation centre
    • Nora, E.P. et al. Spatial partitioning of the regulatory landscape of the X-inactivation centre. Nature 485, 381-385 (2012).
    • (2012) Nature , vol.485 , pp. 381-385
    • Nora, E.P.1
  • 47
    • 84856747483 scopus 로고    scopus 로고
    • Three-dimensional folding and functional organization principles of the Drosophila genome
    • Sexton, T. et al. Three-dimensional folding and functional organization principles of the Drosophila genome. Cell 148, 458-472 (2012).
    • (2012) Cell , vol.148 , pp. 458-472
    • Sexton, T.1
  • 48
    • 72749098124 scopus 로고    scopus 로고
    • Gene loops function to maintain transcriptional memory through interaction with the nuclear pore complex
    • Tan-Wong, S.M., Wijayatilake, H.D. & Proudfoot, N.J. Gene loops function to maintain transcriptional memory through interaction with the nuclear pore complex. Genes Dev. 23, 2610-2624 (2009).
    • (2009) Genes Dev. , vol.23 , pp. 2610-2624
    • Tan-Wong, S.M.1    Wijayatilake, H.D.2    Proudfoot, N.J.3
  • 49
    • 77956647538 scopus 로고    scopus 로고
    • Do chromatin loops provide epigenetic gene expression states?
    • Deng, W. & Blobel, G.A. Do chromatin loops provide epigenetic gene expression states? Curr. Opin. Genet. Dev. 20, 548-554 (2010).
    • (2010) Curr. Opin. Genet. Dev. , vol.20 , pp. 548-554
    • Deng, W.1    Blobel, G.A.2
  • 50
    • 84867003195 scopus 로고    scopus 로고
    • Robust 4C-seq data analysis to screen for regulatory DNA interactions
    • van de Werken, H.J. et al. Robust 4C-seq data analysis to screen for regulatory DNA interactions. Nat. Methods 9, 969-972 (2012).
    • (2012) Nat. Methods , vol.9 , pp. 969-972
    • Van De Werken, H.J.1
  • 51
    • 70349873824 scopus 로고    scopus 로고
    • Comprehensive mapping of long-range interactions reveals folding principles of the human genome
    • Lieberman-Aiden, E. et al. Comprehensive mapping of long-range interactions reveals folding principles of the human genome. Science 326, 289-293 (2009).
    • (2009) Science , vol.326 , pp. 289-293
    • Lieberman-Aiden, E.1
  • 52
    • 0036144048 scopus 로고    scopus 로고
    • DNA methylation patterns and epigenetic memory
    • Bird, A. DNA methylation patterns and epigenetic memory. Genes Dev. 16, 6-21 (2002).
    • (2002) Genes Dev. , vol.16 , pp. 6-21
    • Bird, A.1
  • 53
    • 77956189495 scopus 로고    scopus 로고
    • Role of Tet proteins in 5mC to 5hmC conversion, ES-cell self-renewal and inner cell mass specification
    • Ito, S. et al. Role of Tet proteins in 5mC to 5hmC conversion, ES-cell self-renewal and inner cell mass specification. Nature 466, 1129-1133 (2010).
    • (2010) Nature , vol.466 , pp. 1129-1133
    • Ito, S.1
  • 54
    • 66149146320 scopus 로고    scopus 로고
    • Conversion of 5-methylcytosine to 5-hydroxymethylcytosine in mammalian DNA by MLL partner TET1
    • Tahiliani, M. et al. Conversion of 5-methylcytosine to 5-hydroxymethylcytosine in mammalian DNA by MLL partner TET1. Science 324, 930-935 (2009).
    • (2009) Science , vol.324 , pp. 930-935
    • Tahiliani, M.1
  • 55
    • 80052495940 scopus 로고    scopus 로고
    • Tet-mediated formation of 5-carboxylcytosine and its excision by TDG in mammalian DNA
    • He, Y.F. et al. Tet-mediated formation of 5-carboxylcytosine and its excision by TDG in mammalian DNA. Science 333, 1303-1307 (2011).
    • (2011) Science , vol.333 , pp. 1303-1307
    • He, Y.F.1
  • 56
    • 80052461558 scopus 로고    scopus 로고
    • Tet proteins can convert 5-methylcytosine to 5-formylcytosine and 5-carboxylcytosine
    • Ito, S. et al. Tet proteins can convert 5-methylcytosine to 5-formylcytosine and 5-carboxylcytosine. Science 333, 1300-1303 (2011).
    • (2011) Science , vol.333 , pp. 1300-1303
    • Ito, S.1
  • 57
    • 84871563384 scopus 로고    scopus 로고
    • MeCP2 binds to 5hmC enriched within active genes and accessible chromatin in the nervous system
    • Mellén, M., Ayata, P., Dewell, S., Kriaucionis, S. & Heintz, N. MeCP2 binds to 5hmC enriched within active genes and accessible chromatin in the nervous system. Cell 151, 1417-1430 (2012).
    • (2012) Cell , vol.151 , pp. 1417-1430
    • Mellén, M.1    Ayata, P.2    Dewell, S.3    Kriaucionis, S.4    Heintz, N.5
  • 58
    • 84455167621 scopus 로고    scopus 로고
    • Mbd3/NURD complex regulates expression of 5-hydroxymethylcytosine marked genes in embryonic stem cells
    • Yildirim, O. et al. Mbd3/NURD complex regulates expression of 5-hydroxymethylcytosine marked genes in embryonic stem cells. Cell 147, 1498-1510 (2011).
    • (2011) Cell , vol.147 , pp. 1498-1510
    • Yildirim, O.1
  • 59
    • 79956292024 scopus 로고    scopus 로고
    • Dual functions of Tet1 in transcriptional regulation in mouse embryonic stem cells
    • Wu, H. et al. Dual functions of Tet1 in transcriptional regulation in mouse embryonic stem cells. Nature 473, 389-393 (2011).
    • (2011) Nature , vol.473 , pp. 389-393
    • Wu, H.1
  • 60
    • 33847055935 scopus 로고    scopus 로고
    • Endogenous cytosine damage products alter the site selectivity of human DNA maintenance methyltransferase DNMT1
    • Valinluck, V. & Sowers, L.C. Endogenous cytosine damage products alter the site selectivity of human DNA maintenance methyltransferase DNMT1. Cancer Res. 67, 946-950 (2007).
    • (2007) Cancer Res. , vol.67 , pp. 946-950
    • Valinluck, V.1    Sowers, L.C.2
  • 61
    • 79955538247 scopus 로고    scopus 로고
    • Hydroxylation of 5-methylcytosine by TET1 promotes active DNA demethylation in the adult brain
    • Guo, J.U., Su, Y., Zhong, C., Ming, G.L. & Song, H. Hydroxylation of 5-methylcytosine by TET1 promotes active DNA demethylation in the adult brain. Cell 145, 423-434 (2011).
    • (2011) Cell , vol.145 , pp. 423-434
    • Guo, J.U.1    Su, Y.2    Zhong, C.3    Ming, G.L.4    Song, H.5
  • 62
    • 79959937861 scopus 로고    scopus 로고
    • Thymine DNA glycosylase is essential for active DNA demethylation by linked deamination-base excision repair
    • Cortellino, S. et al. Thymine DNA glycosylase is essential for active DNA demethylation by linked deamination-base excision repair. Cell 146, 67-79 (2011).
    • (2011) Cell , vol.146 , pp. 67-79
    • Cortellino, S.1
  • 63
    • 79956323623 scopus 로고    scopus 로고
    • Dynamic regulation of 5-hydroxymethylcytosine in mouse ES cells and during differentiation
    • Ficz, G. et al. Dynamic regulation of 5-hydroxymethylcytosine in mouse ES cells and during differentiation. Nature 473, 398-402 (2011).
    • (2011) Nature , vol.473 , pp. 398-402
    • Ficz, G.1
  • 64
    • 79956308473 scopus 로고    scopus 로고
    • Genome-wide mapping of 5-hydroxymethylcytosine in embryonic stem cells
    • Pastor, W.A. et al. Genome-wide mapping of 5-hydroxymethylcytosine in embryonic stem cells. Nature 473, 394-397 (2011).
    • (2011) Nature , vol.473 , pp. 394-397
    • Pastor, W.A.1
  • 65
    • 79956302047 scopus 로고    scopus 로고
    • TET1 and hydroxymethylcytosine in transcription and DNA methylation fidelity
    • Williams, K. et al. TET1 and hydroxymethylcytosine in transcription and DNA methylation fidelity. Nature 473, 343-348 (2011).
    • (2011) Nature , vol.473 , pp. 343-348
    • Williams, K.1
  • 66
    • 79955948324 scopus 로고    scopus 로고
    • Genome-wide regulation of 5hmC, 5mC, and gene expression by Tet1 hydroxylase in mouse embryonic stem cells
    • Xu, Y. et al. Genome-wide regulation of 5hmC, 5mC, and gene expression by Tet1 hydroxylase in mouse embryonic stem cells. Mol. Cell 42, 451-464 (2011).
    • (2011) Mol. Cell , vol.42 , pp. 451-464
    • Xu, Y.1
  • 67
    • 84872953223 scopus 로고    scopus 로고
    • TET2 promotes histone O-GlcNAcylation during gene transcription
    • Chen, Q., Chen, Y., Bian, C., Fujiki, R. & Yu, X. TET2 promotes histone O-GlcNAcylation during gene transcription. Nature 493, 561-564 (2013).
    • (2013) Nature , vol.493 , pp. 561-564
    • Chen, Q.1    Chen, Y.2    Bian, C.3    Fujiki, R.4    Yu, X.5
  • 68
    • 84874266225 scopus 로고    scopus 로고
    • Tet proteins connect the O-linked N-acetylglucosamine transferase Ogt to chromatin in embryonic stem cells
    • Vella, P. et al. Tet proteins connect the O-linked N-acetylglucosamine transferase Ogt to chromatin in embryonic stem cells. Mol. Cell 49, 645-656 (2013).
    • (2013) Mol. Cell , vol.49 , pp. 645-656
    • Vella, P.1
  • 69
    • 79961139741 scopus 로고    scopus 로고
    • Tet1 is dispensable for maintaining pluripotency and its loss is compatible with embryonic and postnatal development
    • Dawlaty, M.M. et al. Tet1 is dispensable for maintaining pluripotency and its loss is compatible with embryonic and postnatal development. Cell Stem Cell 9, 166-175 (2011).
    • (2011) Cell Stem Cell , vol.9 , pp. 166-175
    • Dawlaty, M.M.1
  • 70
    • 79954457998 scopus 로고    scopus 로고
    • Genome-wide analysis of 5-hydroxymethylcytosine distribution reveals its dual function in transcriptional regulation in mouse embryonic stem cells
    • Wu, H. et al. Genome-wide analysis of 5-hydroxymethylcytosine distribution reveals its dual function in transcriptional regulation in mouse embryonic stem cells. Genes Dev. 25, 679-684 (2011).
    • (2011) Genes Dev. , vol.25 , pp. 679-684
    • Wu, H.1
  • 71
    • 84874771985 scopus 로고    scopus 로고
    • Dynamic readers for 5-(hydroxy)methylcytosine and Its oxidized derivatives
    • Spruijt, C.G. et al. Dynamic readers for 5-(hydroxy)methylcytosine and Its oxidized derivatives. Cell 152, 1146-1159 (2013).
    • (2013) Cell , vol.152 , pp. 1146-1159
    • Spruijt, C.G.1
  • 72
    • 84873707539 scopus 로고    scopus 로고
    • Combined deficiency of tet1 and tet2 causes epigenetic abnormalities but is compatible with postnatal development
    • Dawlaty, M.M. et al. Combined deficiency of tet1 and tet2 causes epigenetic abnormalities but is compatible with postnatal development. Dev. Cell 24, 310-323 (2013).
    • (2013) Dev. Cell , vol.24 , pp. 310-323
    • Dawlaty, M.M.1
  • 73
    • 80052284526 scopus 로고    scopus 로고
    • Ten-Eleven-Translocation 2 (TET2) negatively regulates homeostasis and differentiation of hematopoietic stem cells in mice
    • Ko, M. et al. Ten-Eleven-Translocation 2 (TET2) negatively regulates homeostasis and differentiation of hematopoietic stem cells in mice. Proc. Natl. Acad. Sci. USA 108, 14566-14571 (2011).
    • (2011) Proc. Natl. Acad. Sci. USA , vol.108 , pp. 14566-14571
    • Ko, M.1
  • 74
    • 78650175023 scopus 로고    scopus 로고
    • Impaired hydroxylation of 5-methylcytosine in myeloid cancers with mutant TET2
    • Ko, M. et al. Impaired hydroxylation of 5-methylcytosine in myeloid cancers with mutant TET2. Nature 468, 839-843 (2010).
    • (2010) Nature , vol.468 , pp. 839-843
    • Ko, M.1
  • 75
    • 79551587102 scopus 로고    scopus 로고
    • Tet1 and Tet2 regulate 5-hydroxymethylcytosine production and cell lineage specification in mouse embryonic stem cells
    • Koh, K.P. et al. Tet1 and Tet2 regulate 5-hydroxymethylcytosine production and cell lineage specification in mouse embryonic stem cells. Cell Stem Cell 8, 200-213 (2011).
    • (2011) Cell Stem Cell , vol.8 , pp. 200-213
    • Koh, K.P.1
  • 76
    • 80052285127 scopus 로고    scopus 로고
    • Deletion of Tet2 in mice leads to dysregulated hematopoietic stem cells and subsequent development of myeloid malignancies
    • Li, Z. et al. Deletion of Tet2 in mice leads to dysregulated hematopoietic stem cells and subsequent development of myeloid malignancies. Blood 118, 4509-4518 (2011).
    • (2011) Blood , vol.118 , pp. 4509-4518
    • Li, Z.1
  • 77
    • 79960064353 scopus 로고    scopus 로고
    • Tet2 loss leads to increased hematopoietic stem cell self-renewal and myeloid transformation
    • Moran-Crusio, K. et al. Tet2 loss leads to increased hematopoietic stem cell self-renewal and myeloid transformation. Cancer Cell 20, 11-24 (2011).
    • (2011) Cancer Cell , vol.20 , pp. 11-24
    • Moran-Crusio, K.1
  • 78
    • 80052303426 scopus 로고    scopus 로고
    • TET family proteins and their role in stem cell differentiation and transformation
    • Cimmino, L., Abdel-Wahab, O., Levine, R.L. & Aifantis, I. TET family proteins and their role in stem cell differentiation and transformation. Cell Stem Cell 9, 193-204 (2011).
    • (2011) Cell Stem Cell , vol.9 , pp. 193-204
    • Cimmino, L.1    Abdel-Wahab, O.2    Levine, R.L.3    Aifantis, I.4
  • 79
    • 80053348585 scopus 로고    scopus 로고
    • The role of Tet3 DNA dioxygenase in epigenetic reprogramming by oocytes
    • Gu, T.P. et al. The role of Tet3 DNA dioxygenase in epigenetic reprogramming by oocytes. Nature 477, 606-610 (2011).
    • (2011) Nature , vol.477 , pp. 606-610
    • Gu, T.P.1
  • 80
    • 84874194072 scopus 로고    scopus 로고
    • DNA methylation: Roles in mammalian development
    • Smith, Z.D. & Meissner, A. DNA methylation: Roles in mammalian development. Nat. Rev. Genet. 14, 204-220 (2013).
    • (2013) Nat. Rev. Genet. , vol.14 , pp. 204-220
    • Smith, Z.D.1    Meissner, A.2
  • 81
    • 84868103289 scopus 로고    scopus 로고
    • Tet2 facilitates the derepression of myeloid target genes during CEBPalpha-induced transdifferentiation of pre-B cells
    • Kallin, E.M. et al. Tet2 facilitates the derepression of myeloid target genes during CEBPalpha-induced transdifferentiation of pre-B cells. Mol. Cell 48, 266-276 (2012).
    • (2012) Mol. Cell , vol.48 , pp. 266-276
    • Kallin, E.M.1
  • 82
    • 0037340215 scopus 로고    scopus 로고
    • Selective, stable demethylation of the interleukin-2 gene enhances transcription by an active process
    • Bruniquel, D. & Schwartz, R.H. Selective, stable demethylation of the interleukin-2 gene enhances transcription by an active process. Nat. Immunol. 4, 235-240 (2003).
    • (2003) Nat. Immunol. , vol.4 , pp. 235-240
    • Bruniquel, D.1    Schwartz, R.H.2
  • 83
    • 33646058925 scopus 로고    scopus 로고
    • Rapid demethylation of the IFN-? gene occurs in memory but not naive CD8 T cells
    • Kersh, E.N. et al. Rapid demethylation of the IFN-? gene occurs in memory but not naive CD8 T cells. J. Immunol. 176, 4083-4093 (2006).
    • (2006) J. Immunol. , vol.176 , pp. 4083-4093
    • Kersh, E.N.1
  • 84
    • 84866626156 scopus 로고    scopus 로고
    • MicroRNA turnover: When, how, and why
    • Rüegger, S. & Grosshans, H. MicroRNA turnover: When, how, and why. Trends Biochem. Sci. 37, 436-446 (2012).
    • (2012) Trends Biochem. Sci. , vol.37 , pp. 436-446
    • Rüegger, S.1    Grosshans, H.2
  • 85
    • 77449131843 scopus 로고    scopus 로고
    • MicroRNA assassins: Factors that regulate the disappearance of miRNAs
    • Kai, Z.S. & Pasquinelli, A.E. MicroRNA assassins: Factors that regulate the disappearance of miRNAs. Nat. Struct. Mol. Biol. 17, 5-10 (2010).
    • (2010) Nat. Struct. Mol. Biol. , vol.17 , pp. 5-10
    • Kai, Z.S.1    Pasquinelli, A.E.2
  • 86
    • 33744973775 scopus 로고    scopus 로고
    • Relief of microRNA-mediated translational repression in human cells subjected to stress
    • Bhattacharyya, S.N., Habermacher, R., Martine, U., Closs, E.I. & Filipowicz, W. Relief of microRNA-mediated translational repression in human cells subjected to stress. Cell 125, 1111-1124 (2006).
    • (2006) Cell , vol.125 , pp. 1111-1124
    • Bhattacharyya, S.N.1    Habermacher, R.2    Martine, U.3    Closs, E.I.4    Filipowicz, W.5
  • 87
    • 66149167562 scopus 로고    scopus 로고
    • Integration of microRNA miR-122 in hepatic circadian gene expression
    • Gatfield, D. et al. Integration of microRNA miR-122 in hepatic circadian gene expression. Genes Dev. 23, 1313-1326 (2009).
    • (2009) Genes Dev. , vol.23 , pp. 1313-1326
    • Gatfield, D.1
  • 88
    • 34247589595 scopus 로고    scopus 로고
    • Control of stress-dependent cardiac growth and gene expression by a microRNA
    • van Rooij, E. et al. Control of stress-dependent cardiac growth and gene expression by a microRNA. Science 316, 575-579 (2007).
    • (2007) Science , vol.316 , pp. 575-579
    • Van Rooij, E.1
  • 89
    • 84861116472 scopus 로고    scopus 로고
    • A resource for the conditional ablation of microRNAs in the mouse
    • Park, C.Y. et al. A resource for the conditional ablation of microRNAs in the mouse. Cell Rep 1, 385-391 (2012).
    • (2012) Cell Rep , vol.1 , pp. 385-391
    • Park, C.Y.1
  • 90
    • 78649378267 scopus 로고    scopus 로고
    • MicroRNA functions in stress responses
    • Leung, A.K. & Sharp, P.A. MicroRNA functions in stress responses. Mol. Cell 40, 205-215 (2010).
    • (2010) Mol. Cell , vol.40 , pp. 205-215
    • Leung, A.K.1    Sharp, P.A.2
  • 92
    • 79952364512 scopus 로고    scopus 로고
    • Kinetic analysis reveals the fate of a microRNA following target regulation in mammalian cells
    • Baccarini, A. et al. Kinetic analysis reveals the fate of a microRNA following target regulation in mammalian cells. Curr. Biol. 21, 369-376 (2011).
    • (2011) Curr. Biol. , vol.21 , pp. 369-376
    • Baccarini, A.1
  • 93
    • 84862777377 scopus 로고    scopus 로고
    • Secreted microRNAs: A new form of intercellular communication
    • Chen, X., Liang, H., Zhang, J., Zen, K. & Zhang, C.Y. Secreted microRNAs: A new form of intercellular communication. Trends Cell Biol. 22, 125-132 (2012).
    • (2012) Trends Cell Biol. , vol.22 , pp. 125-132
    • Chen, X.1    Liang, H.2    Zhang, J.3    Zen, K.4    Zhang, C.Y.5
  • 94
    • 84862908547 scopus 로고    scopus 로고
    • Mechanism of transfer of functional microRNAs between mouse dendritic cells via exosomes
    • Montecalvo, A. et al. Mechanism of transfer of functional microRNAs between mouse dendritic cells via exosomes. Blood 119, 756-766 (2012).
    • (2012) Blood , vol.119 , pp. 756-766
    • Montecalvo, A.1
  • 95
    • 34249302620 scopus 로고    scopus 로고
    • Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells
    • Valadi, H. et al. Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells. Nat. Cell Biol. 9, 654-659 (2007).
    • (2007) Nat. Cell Biol. , vol.9 , pp. 654-659
    • Valadi, H.1
  • 96
    • 77954257796 scopus 로고    scopus 로고
    • Secreted monocytic miR-150 enhances targeted endothelial cell migration
    • Zhang, Y. et al. Secreted monocytic miR-150 enhances targeted endothelial cell migration. Mol. Cell 39, 133-144 (2010).
    • (2010) Mol. Cell , vol.39 , pp. 133-144
    • Zhang, Y.1
  • 97
    • 84868689316 scopus 로고    scopus 로고
    • MiR-146a and NF-κB1 regulate mast cell survival and T lymphocyte differentiation
    • Rusca, N. et al. MiR-146a and NF-κB1 regulate mast cell survival and T lymphocyte differentiation. Mol. Cell Biol. 32, 4432-4444 (2012).
    • (2012) Mol. Cell Biol. , vol.32 , pp. 4432-4444
    • Rusca, N.1
  • 98
    • 33747608638 scopus 로고    scopus 로고
    • NF-κB-dependent induction of microRNA miR-146, an inhibitor targeted to signaling proteins of innate immune responses
    • Taganov, K.D., Boldin, M.P., Chang, K.J. & Baltimore, D. NF-κB-dependent induction of microRNA miR-146, an inhibitor targeted to signaling proteins of innate immune responses. Proc. Natl. Acad. Sci. USA 103, 12481-12486 (2006).
    • (2006) Proc. Natl. Acad. Sci. USA , vol.103 , pp. 12481-12486
    • Taganov, K.D.1    Boldin, M.P.2    Chang, K.J.3    Baltimore, D.4
  • 99
    • 84866354593 scopus 로고    scopus 로고
    • MiR-146a controls the resolution of T cell responses in mice
    • Yang, L. et al. miR-146a controls the resolution of T cell responses in mice. J. Exp. Med. 209, 1655-1670 (2012).
    • (2012) J. Exp. Med. , vol.209 , pp. 1655-1670
    • Yang, L.1
  • 100
    • 79958257077 scopus 로고    scopus 로고
    • MiR-146a is a significant brake on autoimmunity, myeloproliferation, and cancer in mice
    • Boldin, M.P. et al. miR-146a is a significant brake on autoimmunity, myeloproliferation, and cancer in mice. J. Exp. Med. 208, 1189-1201 (2011).
    • (2011) J. Exp. Med. , vol.208 , pp. 1189-1201
    • Boldin, M.P.1
  • 101
    • 79959362128 scopus 로고    scopus 로고
    • NF-κB dysregulation in microRNA-146a-deficient mice drives the development of myeloid malignancies
    • Zhao, J.L. et al. NF-κB dysregulation in microRNA-146a-deficient mice drives the development of myeloid malignancies. Proc. Natl. Acad. Sci. USA 108, 9184-9189 (2011).
    • (2011) Proc. Natl. Acad. Sci. USA , vol.108 , pp. 9184-9189
    • Zhao, J.L.1
  • 102
    • 84858722006 scopus 로고    scopus 로고
    • MicroRNAs, new effectors and regulators of NF-κB
    • Boldin, M.P. & Baltimore, D. MicroRNAs, new effectors and regulators of NF-κB. Immunol. Rev. 246, 205-220 (2012).
    • (2012) Immunol. Rev. , vol.246 , pp. 205-220
    • Boldin, M.P.1    Baltimore, D.2
  • 104
    • 34247584465 scopus 로고    scopus 로고
    • Requirement of bic/microRNA-155 for normal immune function
    • Rodriguez, A. et al. Requirement of bic/microRNA-155 for normal immune function. Science 316, 608-611 (2007).
    • (2007) Science , vol.316 , pp. 608-611
    • Rodriguez, A.1
  • 105
    • 34247594818 scopus 로고    scopus 로고
    • Regulation of the germinal center response by microRNA-155
    • Thai, T.H. et al. Regulation of the germinal center response by microRNA-155. Science 316, 604-608 (2007).
    • (2007) Science , vol.316 , pp. 604-608
    • Thai, T.H.1
  • 106
    • 84857466240 scopus 로고    scopus 로고
    • MicroRNA miR-150 is involved in Vα14 invariant NKT cell development and function
    • Zheng, Q., Zhou, L. & Mi, Q.S. MicroRNA miR-150 is involved in Vα14 invariant NKT cell development and function. J. Immunol. 188, 2118-2126 (2012).
    • (2012) J. Immunol. , vol.188 , pp. 2118-2126
    • Zheng, Q.1    Zhou, L.2    Mi, Q.S.3
  • 107
    • 80053981443 scopus 로고    scopus 로고
    • MiR-221 influences effector functions and actin cytoskeleton in mast cells
    • Mayoral, R.J. et al. MiR-221 influences effector functions and actin cytoskeleton in mast cells. PLoS ONE 6, e26133 (2011).
    • (2011) Plos One , vol.6
    • Mayoral, R.J.1
  • 108
    • 84868568561 scopus 로고    scopus 로고
    • IL-10-induced microRNA-187 negatively regulates TNF-α, IL-6, and IL-12p40 production in TLR4-stimulated monocytes
    • Rossato, M. et al. IL-10-induced microRNA-187 negatively regulates TNF-α, IL-6, and IL-12p40 production in TLR4-stimulated monocytes. Proc. Natl. Acad. Sci. USA 109, E3101-E3110 (2012).
    • (2012) Proc. Natl. Acad. Sci. USA , vol.109
    • Rossato, M.1
  • 110
    • 84855501133 scopus 로고    scopus 로고
    • MiR-150 regulates the development of NK and iNKT cells
    • Bezman, N.A., Chakraborty, T., Bender, T. & Lanier, L.L. miR-150 regulates the development of NK and iNKT cells. J. Exp. Med. 208, 2717-2731 (2011).
    • (2011) J. Exp. Med. , vol.208 , pp. 2717-2731
    • Bezman, N.A.1    Chakraborty, T.2    Bender, T.3    Lanier, L.L.4
  • 111
    • 84874573555 scopus 로고    scopus 로고
    • T cell activation induces proteasomal degradation of Argonaute and rapid remodeling of the microRNA repertoire
    • Bronevetsky, Y. et al. T cell activation induces proteasomal degradation of Argonaute and rapid remodeling of the microRNA repertoire. J. Exp. Med. 210, 417-432 (2013).
    • (2013) J. Exp. Med. , vol.210 , pp. 417-432
    • Bronevetsky, Y.1
  • 112
    • 36849048778 scopus 로고    scopus 로고
    • Dual role for argonautes in microRNA processing and posttranscriptional regulation of microRNA expression
    • Diederichs, S. & Haber, D.A. Dual role for argonautes in microRNA processing and posttranscriptional regulation of microRNA expression. Cell 131, 1097-1108 (2007).
    • (2007) Cell , vol.131 , pp. 1097-1108
    • Diederichs, S.1    Haber, D.A.2
  • 113
    • 34547955952 scopus 로고    scopus 로고
    • A Slicer-independent role for Argonaute 2 in hematopoiesis and the microRNA pathway
    • ÓCarroll, D. et al. A Slicer-independent role for Argonaute 2 in hematopoiesis and the microRNA pathway. Genes Dev. 21, 1999-2004 (2007).
    • (2007) Genes Dev. , vol.21 , pp. 1999-2004
    • ÓCarroll, D.1
  • 114
    • 84871959206 scopus 로고    scopus 로고
    • Long-lived microRNA-Argonaute complexes in quiescent cells can be activated to regulate mitogenic responses
    • Olejniczak, S.H., La Rocca, G., Gruber, J.J. & Thompson, C.B. Long-lived microRNA-Argonaute complexes in quiescent cells can be activated to regulate mitogenic responses. Proc. Natl. Acad. Sci. USA 110, 157-162 (2013).
    • (2013) Proc. Natl. Acad. Sci. USA , vol.110 , pp. 157-162
    • Olejniczak, S.H.1    La Rocca, G.2    Gruber, J.J.3    Thompson, C.B.4
  • 115
    • 70349453924 scopus 로고    scopus 로고
    • Active turnover modulates mature microRNA activity in Caenorhabditis elegans
    • Chatterjee, S. & Grosshans, H. Active turnover modulates mature microRNA activity in Caenorhabditis elegans. Nature 461, 546-549 (2009).
    • (2009) Nature , vol.461 , pp. 546-549
    • Chatterjee, S.1    Grosshans, H.2
  • 116
    • 77952479722 scopus 로고    scopus 로고
    • Characterizing light-regulated retinal microRNAs reveals rapid turnover as a common property of neuronal microRNAs
    • Krol, J. et al. Characterizing light-regulated retinal microRNAs reveals rapid turnover as a common property of neuronal microRNAs. Cell 141, 618-631 (2010).
    • (2010) Cell , vol.141 , pp. 618-631
    • Krol, J.1
  • 117
    • 84875372911 scopus 로고    scopus 로고
    • Natural RNA circles function as efficient microRNA sponges
    • Hansen, T.B. et al. Natural RNA circles function as efficient microRNA sponges. Nature 495, 384-388 (2013).
    • (2013) Nature , vol.495 , pp. 384-388
    • Hansen, T.B.1
  • 118
    • 84863594456 scopus 로고    scopus 로고
    • Eri1 regulates microRNA homeostasis and mouse lymphocyte development and antiviral function
    • Thomas, M.F. et al. Eri1 regulates microRNA homeostasis and mouse lymphocyte development and antiviral function. Blood 120, 130-142 (2012).
    • (2012) Blood , vol.120 , pp. 130-142
    • Thomas, M.F.1
  • 119
    • 84865757142 scopus 로고    scopus 로고
    • Landscape of transcription in human cells
    • Djebali, S. et al. Landscape of transcription in human cells. Nature 489, 101-108 (2012).
    • (2012) Nature , vol.489 , pp. 101-108
    • Djebali, S.1
  • 120
    • 84857066786 scopus 로고    scopus 로고
    • Modular regulatory principles of large non-coding RNAs
    • Guttman, M. & Rinn, J.L. Modular regulatory principles of large non-coding RNAs. Nature 482, 339-346 (2012).
    • (2012) Nature , vol.482 , pp. 339-346
    • Guttman, M.1    Rinn, J.L.2
  • 121
    • 80053045739 scopus 로고    scopus 로고
    • Molecular mechanisms of long noncoding RNAs
    • Wang, K.C. & Chang, H.Y. Molecular mechanisms of long noncoding RNAs. Mol. Cell 43, 904-914 (2011).
    • (2011) Mol. Cell , vol.43 , pp. 904-914
    • Wang, K.C.1    Chang, H.Y.2
  • 122
    • 60149099385 scopus 로고    scopus 로고
    • Evolution and functions of long noncoding RNAs
    • Ponting, C.P., Oliver, P.L. & Reik, W. Evolution and functions of long noncoding RNAs. Cell 136, 629-641 (2009).
    • (2009) Cell , vol.136 , pp. 629-641
    • Ponting, C.P.1    Oliver, P.L.2    Reik, W.3
  • 123
    • 24644481406 scopus 로고    scopus 로고
    • A strategy for probing the function of noncoding RNAs finds a repressor of NFAT
    • Willingham, A.T. et al. A strategy for probing the function of noncoding RNAs finds a repressor of NFAT. Science 309, 1570-1573 (2005).
    • (2005) Science , vol.309 , pp. 1570-1573
    • Willingham, A.T.1
  • 124
    • 79960984904 scopus 로고    scopus 로고
    • Dephosphorylation of the nuclear factor of activated T cells (NFAT) transcription factor is regulated by an RNA-protein scaffold complex
    • Sharma, S. et al. Dephosphorylation of the nuclear factor of activated T cells (NFAT) transcription factor is regulated by an RNA-protein scaffold complex. Proc. Natl. Acad. Sci. USA 108, 11381-11386 (2011).
    • (2011) Proc. Natl. Acad. Sci. USA , vol.108 , pp. 11381-11386
    • Sharma, S.1
  • 125
    • 77955323879 scopus 로고    scopus 로고
    • A large intergenic noncoding RNA induced by p53 mediates global gene repression in the p53 response
    • Huarte, M. et al. A large intergenic noncoding RNA induced by p53 mediates global gene repression in the p53 response. Cell 142, 409-419 (2010).
    • (2010) Cell , vol.142 , pp. 409-419
    • Huarte, M.1
  • 126
    • 79959756263 scopus 로고    scopus 로고
    • Extensive and coordinated transcription of noncoding RNAs within cell-cycle promoters
    • Hung, T. et al. Extensive and coordinated transcription of noncoding RNAs within cell-cycle promoters. Nat. Genet. 43, 621-629 (2011).
    • (2011) Nat. Genet. , vol.43 , pp. 621-629
    • Hung, T.1
  • 127
    • 77957243921 scopus 로고    scopus 로고
    • Long noncoding RNAs with enhancer-like function in human cells
    • Ørom, U.A. et al. Long noncoding RNAs with enhancer-like function in human cells. Cell 143, 46-58 (2010).
    • (2010) Cell , vol.143 , pp. 46-58
    • Ørom, U.A.1
  • 128
    • 84874025014 scopus 로고    scopus 로고
    • The NeST long ncRNA controls microbial susceptibility and epigenetic activation of the interferon-gamma locus
    • Gomez, J.A. et al. The NeST long ncRNA controls microbial susceptibility and epigenetic activation of the interferon-gamma locus. Cell 152, 743-754 (2013).
    • (2013) Cell , vol.152 , pp. 743-754
    • Gomez, J.A.1
  • 129
    • 77953957633 scopus 로고    scopus 로고
    • A coding-independent function of gene and pseudogene mRNAs regulates tumour biology
    • Poliseno, L. et al. A coding-independent function of gene and pseudogene mRNAs regulates tumour biology. Nature 465, 1033-1038 (2010).
    • (2010) Nature , vol.465 , pp. 1033-1038
    • Poliseno, L.1
  • 130
    • 79961170994 scopus 로고    scopus 로고
    • A ceRNA hypo thesis: The rosetta stone of a hidden rna language?
    • Salmena, L., Poliseno, L., Tay, Y., Kats, L. & Pandolfi, P.P. A ceRNA hypothesis: The Rosetta Stone of a hidden RNA language? Cell 146, 353-358 (2011).
    • (2011) Cell , vol.146 , pp. 353-358
    • Salmena, L.1    Poliseno, L.2    Tay, Y.3    Kats, L.4    Pandolfi, P.P.5
  • 131
    • 84874273811 scopus 로고    scopus 로고
    • The transcription factor NFAT exhibits signal memory during serial T cell interactions with antigen-presenting cells
    • Marangoni, F. et al. The transcription factor NFAT exhibits signal memory during serial T cell interactions with antigen-presenting cells. Immunity 38, 237-249 (2013). laboratory) laboratory)
    • (2013) Immunity , vol.38 , pp. 237-249
    • Marangoni, F.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.