Lysine methylation of the NF-κ B subunit RelA by SETD6 couples activity of the histone methyltransferase GLP at chromatin to tonic repression of NF-κ B signaling

Nature Immunology

Volumn 12, Issue 1, 2011, Pages 29-36

  Levy, Dan ^a   Kuo, Alex J ^a   Chang, Yanqi ^b   Schaefer, Uwe ^c   Kitson, Christopher ^d   Cheung, Peggie ^a   Espejo, Alexsandra ^e   Zee, Barry M ^f   Liu, Chih Long ^a,g   Tangsombatvisit, Stephanie ^g   Tennen, Ruth I ^g   Kuo, Andrew Y ^a   Tanjing, Song ^h   Cheung, Regina ^g   Chua, Katrin F ^g,i   Utz, Paul J ^g   Shi, Xiaobing ^h   Prinjha, Rab K ^d   Lee, Kevin ^d   Garcia, Benjamin A ^f   Bedford, Mark T ^e   Tarakhovsky, Alexander ^c   Cheng, Xiaodong ^b   Gozani, Or ^a   more..

^a STANFORD UNIVERSITY   (United States)

^b EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c ROCKEFELLER UNIVERSITY   (United States)

^d GLAXOSMITHKLINE   (United Kingdom)

^e UNIVERSITY OF TEXAS   (United States)

^f PRINCETON UNIVERSITY   (United States)

^g STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^h UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

ⁱ VA PALO ALTO HEALTH CARE SYSTEM   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HISTONE LYSINE METHYLTRANSFERASE; HISTONE METHYLTRANSFERASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LYSINE; METHYLTRANSFERASE; PROTEIN KINASE C ZETA; SERINE; SETD6; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CHROMATIN; CONTROLLED STUDY; ENZYME PHOSPHORYLATION; ENZYME REPRESSION; GENE REPRESSION; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; IMMUNOCOMPETENT CELL; INFLAMMATION; METHYLATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; SCREENING; SIGNAL TRANSDUCTION;

ARTHRITIS, RHEUMATOID; CHROMATIN ASSEMBLY AND DISASSEMBLY; DNA METHYLATION; HEK293 CELLS; HISTONE-LYSINE N-METHYLTRANSFERASE; HISTONES; HUMANS; INFLAMMATION; LYSINE; NF-KAPPA B; PROTEIN BINDING; PROTEIN METHYLTRANSFERASES; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTOR RELA;

EID: 78650308842     PISSN: 15292908     EISSN: 15292916     Source Type: Journal    
DOI: 10.1038/ni.1968     Document Type: Article

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