메뉴 건너뛰기




Volumn 88, Issue 5, 2014, Pages 2748-2762

Genetic complementation of hepatitis C virus nonstructural protein functions associated with replication exhibits requirements that differ from those for virion assembly

Author keywords

[No Author keywords available]

Indexed keywords

HEPATITIS C VIRUS POLYPROTEIN; NONSTRUCTURAL PROTEIN 5A; RNA; UNCLASSIFIED DRUG; VIRUS PROTEIN;

EID: 84896736909     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.03588-13     Document Type: Article
Times cited : (8)

References (81)
  • 1
    • 0026513651 scopus 로고
    • Internal ribosome entry site within hepatitis C virus RNA
    • Tsukiyama-Kohara K, Iizuka N, Kohara M, Nomoto A. 1992. Internal ribosome entry site within hepatitis C virus RNA. J. Virol. 66:1476-1483.
    • (1992) J. Virol. , vol.66 , pp. 1476-1483
    • Tsukiyama-Kohara, K.1    Iizuka, N.2    Kohara, M.3    Nomoto, A.4
  • 2
    • 0027476809 scopus 로고
    • Expression and identification of hepatitis C virus polyprotein cleavage products
    • Grakoui A, Wychowski C, Lin C, Feinstone SM, Rice CM. 1993. Expression and identification of hepatitis C virus polyprotein cleavage products. J. Virol. 67:1385-1395.
    • (1993) J. Virol. , vol.67 , pp. 1385-1395
    • Grakoui, A.1    Wychowski, C.2    Lin, C.3    Feinstone, S.M.4    Rice, C.M.5
  • 3
    • 0028290389 scopus 로고
    • Processing in the hepatitis C virus E2-NS2 region: identification of p7 and two distinct E2-specific products with different C termini
    • Lin C, Lindenbach BD, Pragai BM, McCourt DW, Rice CM. 1994. Processing in the hepatitis C virus E2-NS2 region: identification of p7 and two distinct E2-specific products with different C termini. J. Virol. 68: 5063-5073.
    • (1994) J. Virol. , vol.68 , pp. 5063-5073
    • Lin, C.1    Lindenbach, B.D.2    Pragai, B.M.3    McCourt, D.W.4    Rice, C.M.5
  • 4
    • 0025991559 scopus 로고
    • Gene mapping of the putative structural region of the hepatitis C virus genome by in vitro processing analysis
    • Hijikata M, Kato N, Ootsuyama Y, Nakagawa M, Shimotohno K. 1991. Gene mapping of the putative structural region of the hepatitis C virus genome by in vitro processing analysis. Proc. Natl. Acad. Sci. U. S. A. 88:5547-5551. http://dx.doi.org/10.1073/pnas.88.13.5547.
    • (1991) Proc. Natl. Acad. Sci. U. S. A. , vol.88 , pp. 5547-5551
    • Hijikata, M.1    Kato, N.2    Ootsuyama, Y.3    Nakagawa, M.4    Shimotohno, K.5
  • 5
    • 0036683052 scopus 로고    scopus 로고
    • Intramembrane proteolysis promotes trafficking of hepatitis C virus core protein to lipid droplets
    • McLauchlan J, Lemberg MK, Hope G, Martoglio B. 2002. Intramembrane proteolysis promotes trafficking of hepatitis C virus core protein to lipid droplets. EMBO J. 21:3980-3988. http://dx.doi.org/10.1093/emboj /cdf414.
    • (2002) EMBO J. , vol.21 , pp. 3980-3988
    • McLauchlan, J.1    Lemberg, M.K.2    Hope, G.3    Martoglio, B.4
  • 6
    • 0027414062 scopus 로고
    • Characterization of the hepatitis C virus-encoded serine proteinase: determination of proteinase-dependent polyprotein cleavage sites
    • Grakoui A, McCourt DW, Wychowski C, Feinstone SM, Rice CM. 1993. Characterization of the hepatitis C virus-encoded serine proteinase: determination of proteinase-dependent polyprotein cleavage sites. J. Virol. 67:2832-2843.
    • (1993) J. Virol. , vol.67 , pp. 2832-2843
    • Grakoui, A.1    McCourt, D.W.2    Wychowski, C.3    Feinstone, S.M.4    Rice, C.M.5
  • 7
    • 0027163740 scopus 로고
    • Two distinct proteinase activities required for the processing of a putative nonstructural precursor protein of hepatitis C virus
    • Hijikata M, Mizushima H, Akagi T, Mori S, Kakiuchi N, Kato N, Tanaka T, Kimura K, Shimotohno K. 1993. Two distinct proteinase activities required for the processing of a putative nonstructural precursor protein of hepatitis C virus. J. Virol. 67:4665-4675.
    • (1993) J. Virol. , vol.67 , pp. 4665-4675
    • Hijikata, M.1    Mizushima, H.2    Akagi, T.3    Mori, S.4    Kakiuchi, N.5    Kato, N.6    Tanaka, T.7    Kimura, K.8    Shimotohno, K.9
  • 8
    • 0027176287 scopus 로고
    • NS3 is a serine protease required for processing of hepatitis C virus polyprotein
    • Tomei L, Failla C, Santolini E, De Francesco R, La Monica N. 1993. NS3 is a serine protease required for processing of hepatitis C virus polyprotein. J. Virol. 67:4017-4026.
    • (1993) J. Virol. , vol.67 , pp. 4017-4026
    • Tomei, L.1    Failla, C.2    Santolini, E.3    De Francesco, R.4    La Monica, N.5
  • 9
    • 0034747214 scopus 로고    scopus 로고
    • Sequences in the 5= nontranslated region of hepatitis C virus required for RNA replication
    • Friebe P, Lohmann V, Krieger N, Bartenschlager R. 2001. Sequences in the 5= nontranslated region of hepatitis C virus required for RNA replication. J. Virol. 75:12047-12057. http://dx.doi.org/10.1128/JVI.75.24.12047-12057.2001.
    • (2001) J. Virol. , vol.75 , pp. 12047-12057
    • Friebe, P.1    Lohmann, V.2    Krieger, N.3    Bartenschlager, R.4
  • 10
    • 0033920304 scopus 로고    scopus 로고
    • Hepatitis C virus-encoded enzymatic activities and conserved RNA elements in the 3= nontranslated region are essential for virus replication in vivo
    • Kolykhalov AA, Mihalik K, Feinstone SM, Rice CM. 2000. Hepatitis C virus-encoded enzymatic activities and conserved RNA elements in the 3= nontranslated region are essential for virus replication in vivo. J. Virol. 74:2046-2051. http://dx.doi.org/10.1128/JVI.74.4.2046-2051.2000.
    • (2000) J. Virol. , vol.74 , pp. 2046-2051
    • Kolykhalov, A.A.1    Mihalik, K.2    Feinstone, S.M.3    Rice, C.M.4
  • 11
    • 0033515094 scopus 로고    scopus 로고
    • In vivo analysis of the 3= untranslated region of the hepatitis C virus after in vitro mutagenesis of an infectious cDNA clone
    • Yanagi M, St Claire M, Emerson SU, Purcell RH, Bukh J. 1999. In vivo analysis of the 3= untranslated region of the hepatitis C virus after in vitro mutagenesis of an infectious cDNA clone. Proc. Natl. Acad. Sci. U. S. A. 96:2291-2295. http://dx.doi.org/10.1073/pnas.96.5.2291.
    • (1999) Proc. Natl. Acad. Sci. U. S. A. , vol.96 , pp. 2291-2295
    • Yanagi, M.1    St Claire, M.2    Emerson, S.U.3    Purcell, R.H.4    Bukh, J.5
  • 12
    • 0345188811 scopus 로고    scopus 로고
    • Replication of subgenomic hepatitis C virus RNAs in a hepatoma cell line
    • Lohmann V, Korner F, Koch J, Herian U, Theilmann L, Bartenschlager R. 1999. Replication of subgenomic hepatitis C virus RNAs in a hepatoma cell line. Science 285:110-113. http://dx.doi.org/10.1126/science.285 .5424.110.
    • (1999) Science , vol.285 , pp. 110-113
    • Lohmann, V.1    Korner, F.2    Koch, J.3    Herian, U.4    Theilmann, L.5    Bartenschlager, R.6
  • 13
    • 0345144016 scopus 로고    scopus 로고
    • Identification of the hepatitis C virus RNA replication complex in Huh-7 cells harboring subgenomic replicons
    • Gosert R, Egger D, Lohmann V, Bartenschlager R, Blum HE, Bienz K, Moradpour D. 2003. Identification of the hepatitis C virus RNA replication complex in Huh-7 cells harboring subgenomic replicons. J. Virol. 77:5487-5492. http://dx.doi.org/10.1128/JVI.77.9.5487-5492.2003.
    • (2003) J. Virol. , vol.77 , pp. 5487-5492
    • Gosert, R.1    Egger, D.2    Lohmann, V.3    Bartenschlager, R.4    Blum, H.E.5    Bienz, K.6    Moradpour, D.7
  • 15
    • 84885995316 scopus 로고    scopus 로고
    • Morphological and biochemical characterization of the membranous hepatitis C virus replication compartment
    • Paul D, Hoppe S, Saher G, Krijnse-Locker J, Bartenschlager R. 2013. Morphological and biochemical characterization of the membranous hepatitis C virus replication compartment. J. Virol. 87:10612-10627. http: //dx.doi.org/10.1128/JVI.01370-13.
    • (2013) J. Virol. , vol.87 , pp. 10612-10627
    • Paul, D.1    Hoppe, S.2    Saher, G.3    Krijnse-Locker, J.4    Bartenschlager, R.5
  • 16
    • 0028089739 scopus 로고
    • Hepatitis C virus NS3 serine proteinase: trans-cleavage requirements and processing kinetics
    • Lin C, Pragai BM, Grakoui A, Xu J, Rice CM. 1994. Hepatitis C virus NS3 serine proteinase: trans-cleavage requirements and processing kinetics. J. Virol. 68:8147-8157.
    • (1994) J. Virol. , vol.68 , pp. 8147-8157
    • Lin, C.1    Pragai, B.M.2    Grakoui, A.3    Xu, J.4    Rice, C.M.5
  • 17
    • 0028831056 scopus 로고
    • Hepatitis C virus-encoded nonstructural protein NS4A has versatile functions in viral protein processing
    • Tanji Y, Hijikata M, Satoh S, Kaneko T, Shimotohno K. 1995. Hepatitis C virus-encoded nonstructural protein NS4A has versatile functions in viral protein processing. J. Virol. 69:1575-1581.
    • (1995) J. Virol. , vol.69 , pp. 1575-1581
    • Tanji, Y.1    Hijikata, M.2    Satoh, S.3    Kaneko, T.4    Shimotohno, K.5
  • 18
    • 0030051777 scopus 로고    scopus 로고
    • Identification and properties of the RNA-dependent RNA polymerase of hepatitis C virus
    • Behrens SE, Tomei L, De Francesco R. 1996. Identification and properties of the RNA-dependent RNA polymerase of hepatitis C virus. EMBO J. 15:12-22.
    • (1996) EMBO J. , vol.15 , pp. 12-22
    • Behrens, S.E.1    Tomei, L.2    De Francesco, R.3
  • 19
    • 51349138269 scopus 로고    scopus 로고
    • Discovery of a hepatitis C target and its pharmacological inhibitors by microfluidic affinity analysis
    • Einav S, Gerber D, Bryson PD, Sklan EH, Elazar M, Maerkl SJ, Glenn JS, Quake SR. 2008. Discovery of a hepatitis C target and its pharmacological inhibitors by microfluidic affinity analysis. Nat. Biotechnol. 26: 1019-1027. http://dx.doi.org/10.1038/nbt.1490.
    • (2008) Nat. Biotechnol. , vol.26 , pp. 1019-1027
    • Einav, S.1    Gerber, D.2    Bryson, P.D.3    Sklan, E.H.4    Elazar, M.5    Maerkl, S.J.6    Glenn, J.S.7    Quake, S.R.8
  • 21
    • 0036100578 scopus 로고    scopus 로고
    • Expression of hepatitis C virus proteins induces distinct membrane alterations including a candidate viral replication complex
    • Egger D, Wolk B, Gosert R, Bianchi L, Blum HE, Moradpour D, Bienz K. 2002. Expression of hepatitis C virus proteins induces distinct membrane alterations including a candidate viral replication complex. J. Virol. 76:5974-5984. http://dx.doi.org/10.1128/JVI.76.12.5974-5984.2002.
    • (2002) J. Virol. , vol.76 , pp. 5974-5984
    • Egger, D.1    Wolk, B.2    Gosert, R.3    Bianchi, L.4    Blum, H.E.5    Moradpour, D.6    Bienz, K.7
  • 22
    • 0037040923 scopus 로고    scopus 로고
    • An amino-terminal amphipathic alpha-helix mediates membrane association of the hepatitisCvirus nonstructural protein 5A
    • Brass V, Bieck E, Montserret R, Wolk B, Hellings JA, Blum HE, Penin F, Moradpour D. 2002. An amino-terminal amphipathic alpha-helix mediates membrane association of the hepatitisCvirus nonstructural protein 5A. J. Biol. Chem. 277:8130-8139. http://dx.doi.org/10.1074/jbc.M111 289200.
    • (2002) J. Biol. Chem. , vol.277 , pp. 8130-8139
    • Brass, V.1    Bieck, E.2    Montserret, R.3    Wolk, B.4    Hellings, J.A.5    Blum, H.E.6    Penin, F.7    Moradpour, D.8
  • 23
    • 4644281168 scopus 로고    scopus 로고
    • An N-terminal amphipathic helix in hepatitis C virus (HCV) NS4B mediates membrane association, correct localization of replication complex proteins, and HCV RNA replication
    • Elazar M, Liu P, Rice CM, Glenn JS. 2004. An N-terminal amphipathic helix in hepatitis C virus (HCV) NS4B mediates membrane association, correct localization of replication complex proteins, and HCV RNA replication. J. Virol. 78:11393-11400. http://dx.doi.org/10.1128/JVI.78.20 .11393-11400.2004.
    • (2004) J. Virol. , vol.78 , pp. 11393-11400
    • Elazar, M.1    Liu, P.2    Rice, C.M.3    Glenn, J.S.4
  • 24
    • 70350330475 scopus 로고    scopus 로고
    • An amphipathic alpha-helix at the C terminus of hepatitis C virus nonstructural protein 4B mediates membrane association
    • Gouttenoire J, Montserret R, Kennel A, Penin F, Moradpour D. 2009. An amphipathic alpha-helix at the C terminus of hepatitis C virus nonstructural protein 4B mediates membrane association. J. Virol. 83:11378-11384. http://dx.doi.org/10.1128/JVI.01122-09.
    • (2009) J. Virol. , vol.83 , pp. 11378-11384
    • Gouttenoire, J.1    Montserret, R.2    Kennel, A.3    Penin, F.4    Moradpour, D.5
  • 26
    • 78649398569 scopus 로고    scopus 로고
    • Amphipathic alpha-helix AH2 is a major determinant for the oligomerization of hepatitis C virus nonstructural protein 4B
    • Gouttenoire J, Roingeard P, Penin F, Moradpour D. 2010. Amphipathic alpha-helix AH2 is a major determinant for the oligomerization of hepatitis C virus nonstructural protein 4B. J. Virol. 84:12529-12537. http://dx .doi.org/10.1128/JVI.01798-10.
    • (2010) J. Virol. , vol.84 , pp. 12529-12537
    • Gouttenoire, J.1    Roingeard, P.2    Penin, F.3    Moradpour, D.4
  • 27
    • 78649430973 scopus 로고    scopus 로고
    • Hepatitis C virus nonstructural protein 5A: biochemical characterization of a novel structural class of RNA-binding proteins
    • Hwang J, Huang L, Cordek DG, Vaughan R, Reynolds SL, Kihara G, Raney KD, Kao CC, Cameron CE. 2010. Hepatitis C virus nonstructural protein 5A: biochemical characterization of a novel structural class of RNA-binding proteins. J. Virol. 84:12480-12491. http://dx.doi.org/10 .1128/JVI.01319-10.
    • (2010) J. Virol. , vol.84 , pp. 12480-12491
    • Hwang, J.1    Huang, L.2    Cordek, D.G.3    Vaughan, R.4    Reynolds, S.L.5    Kihara, G.6    Raney, K.D.7    Kao, C.C.8    Cameron, C.E.9
  • 28
    • 33744921881 scopus 로고    scopus 로고
    • Palmitoylation and polymerization of hepatitis C virus NS4B protein
    • Yu GY, Lee KJ, Gao L, Lai MM. 2006. Palmitoylation and polymerization of hepatitis C virus NS4B protein. J. Virol. 80:6013-6023. http://dx.doi .org/10.1128/JVI.00053-06.
    • (2006) J. Virol. , vol.80 , pp. 6013-6023
    • Yu, G.Y.1    Lee, K.J.2    Gao, L.3    Lai, M.M.4
  • 29
    • 28444476999 scopus 로고    scopus 로고
    • Membrane curvature and mechanisms of dynamic cell membrane remodelling
    • McMahon HT, Gallop JL. 2005. Membrane curvature and mechanisms of dynamic cell membrane remodelling. Nature 438:590-596. http://dx .doi.org/10.1038/nature04396.
    • (2005) Nature , vol.438 , pp. 590-596
    • McMahon, H.T.1    Gallop, J.L.2
  • 32
    • 39749119301 scopus 로고    scopus 로고
    • Visualization of double-stranded RNA in cells supporting hepatitis C virus RNA replication
    • Targett-Adams P, Boulant S, McLauchlan J. 2008. Visualization of double-stranded RNA in cells supporting hepatitis C virus RNA replication. J. Virol. 82:2182-2195. http://dx.doi.org/10.1128/JVI.01565-07.
    • (2008) J. Virol. , vol.82 , pp. 2182-2195
    • Targett-Adams, P.1    Boulant, S.2    McLauchlan, J.3
  • 33
    • 80055073369 scopus 로고    scopus 로고
    • Trafficking of hepatitis C virus core protein during virus particle assembly
    • Counihan NA, Rawlinson SM, Lindenbach BD. 2011. Trafficking of hepatitis C virus core protein during virus particle assembly. PLoS Pathog. 7:e1002302. http://dx.doi.org/10.1371/journal.ppat.1002302.
    • (2011) PLoS Pathog. , vol.7
    • Counihan, N.A.1    Rawlinson, S.M.2    Lindenbach, B.D.3
  • 37
    • 84880380982 scopus 로고    scopus 로고
    • Modulation of hepatitis C virus genome encapsidation by nonstructural protein 4B
    • Han Q, Manna D, Belton K, Cole R, Konan KV. 2013. Modulation of hepatitis C virus genome encapsidation by nonstructural protein 4B. J. Virol. 87:7409-7422. http://dx.doi.org/10.1128/JVI.03523-12.
    • (2013) J. Virol. , vol.87 , pp. 7409-7422
    • Han, Q.1    Manna, D.2    Belton, K.3    Cole, R.4    Konan, K.V.5
  • 38
    • 60049083503 scopus 로고    scopus 로고
    • The hepatitis C virus NS4B protein can trans-complement viral RNA replication and modulates production of infectious virus
    • Jones DM, Patel AH, Targett-Adams P, McLauchlan J. 2009. The hepatitis C virus NS4B protein can trans-complement viral RNA replication and modulates production of infectious virus. J. Virol. 83:2163-2177. http://dx.doi.org/10.1128/JVI.01885-08.
    • (2009) J. Virol. , vol.83 , pp. 2163-2177
    • Jones, D.M.1    Patel, A.H.2    Targett-Adams, P.3    McLauchlan, J.4
  • 39
    • 81255200368 scopus 로고    scopus 로고
    • A genetic interaction between the core and NS3 proteins of hepatitis C virus is essential for production of infectious virus
    • Jones DM, Atoom AM, Zhang X, Kottilil S, Russell RS. 2011. A genetic interaction between the core and NS3 proteins of hepatitis C virus is essential for production of infectious virus. J. Virol. 85:12351-12361. http: //dx.doi.org/10.1128/JVI.05313-11.
    • (2011) J. Virol. , vol.85 , pp. 12351-12361
    • Jones, D.M.1    Atoom, A.M.2    Zhang, X.3    Kottilil, S.4    Russell, R.S.5
  • 40
    • 47749092840 scopus 로고    scopus 로고
    • NS3 helicase domains involved in infectious intracellular hepatitis C virus particle assembly
    • Ma Y, Yates J, Liang Y, Lemon SM, Yi M. 2008. NS3 helicase domains involved in infectious intracellular hepatitis C virus particle assembly. J. Virol. 82:7624-7639. http://dx.doi.org/10.1128/JVI.00724-08.
    • (2008) J. Virol. , vol.82 , pp. 7624-7639
    • Ma, Y.1    Yates, J.2    Liang, Y.3    Lemon, S.M.4    Yi, M.5
  • 41
    • 49149113893 scopus 로고    scopus 로고
    • Interaction of hepatitis C virus nonstructural protein 5A with core protein is critical for the production of infectious virus particles
    • Masaki T, Suzuki R, Murakami K, Aizaki H, Ishii K, Murayama A, Date T, Matsuura Y, Miyamura T, Wakita T, Suzuki T. 2008. Interaction of hepatitis C virus nonstructural protein 5A with core protein is critical for the production of infectious virus particles. J. Virol. 82:7964-7976. http: //dx.doi.org/10.1128/JVI.00826-08.
    • (2008) J. Virol. , vol.82 , pp. 7964-7976
    • Masaki, T.1    Suzuki, R.2    Murakami, K.3    Aizaki, H.4    Ishii, K.5    Murayama, A.6    Date, T.7    Matsuura, Y.8    Miyamura, T.9    Wakita, T.10    Suzuki, T.11
  • 42
    • 79960406328 scopus 로고    scopus 로고
    • NS4B self-interaction through conserved C-terminal elements is required for the establishment of functional hepatitis C virus replication complexes
    • Paul D, Romero-Brey I, Gouttenoire J, Stoitsova S, Krijnse-Locker J, Moradpour D, Bartenschlager R. 2011. NS4B self-interaction through conserved C-terminal elements is required for the establishment of functional hepatitis C virus replication complexes. J. Virol. 85:6963-6976. http://dx.doi.org/10.1128/JVI.00502-11.
    • (2011) J. Virol. , vol.85 , pp. 6963-6976
    • Paul, D.1    Romero-Brey, I.2    Gouttenoire, J.3    Stoitsova, S.4    Krijnse-Locker, J.5    Moradpour, D.6    Bartenschlager, R.7
  • 43
    • 69249231061 scopus 로고    scopus 로고
    • Hepatitis C virus NS2 protein contributes to virus particle assembly via opposing epistatic interactions with the E1-E2 glycoprotein and NS3-NS4A enzyme complexes
    • Phan T, Beran RK, Peters C, Lorenz IC, Lindenbach BD. 2009. Hepatitis C virus NS2 protein contributes to virus particle assembly via opposing epistatic interactions with the E1-E2 glycoprotein and NS3-NS4A enzyme complexes. J. Virol. 83:8379-8395. http://dx.doi.org/10.1128/JVI.00891-09.
    • (2009) J. Virol. , vol.83 , pp. 8379-8395
    • Phan, T.1    Beran, R.K.2    Peters, C.3    Lorenz, I.C.4    Lindenbach, B.D.5
  • 44
    • 78651399012 scopus 로고    scopus 로고
    • The acidic domain of hepatitis C virus NS4A contributes to RNA replication and virus particle assembly
    • Phan T, Kohlway A, Dimberu P, Pyle AM, Lindenbach BD. 2011. The acidic domain of hepatitis C virus NS4A contributes to RNA replication and virus particle assembly. J. Virol. 85:1193-1204. http://dx.doi.org/10 .1128/JVI.01889-10.
    • (2011) J. Virol. , vol.85 , pp. 1193-1204
    • Phan, T.1    Kohlway, A.2    Dimberu, P.3    Pyle, A.M.4    Lindenbach, B.D.5
  • 47
    • 42949145532 scopus 로고    scopus 로고
    • Regulation of hepatitis C virion production via phosphorylation of the NS5A protein
    • Tellinghuisen TL, Foss KL, Treadaway J. 2008. Regulation of hepatitis C virion production via phosphorylation of the NS5A protein. PLoS Pathog. 4:e1000032. http://dx.doi.org/10.1371/journal.ppat.1000032.
    • (2008) PLoS Pathog. , vol.4
    • Tellinghuisen, T.L.1    Foss, K.L.2    Treadaway, J.3
  • 48
    • 33846111662 scopus 로고    scopus 로고
    • Compensatory mutations in E1, p7, NS2, and NS3 enhance yields of cell culture-infectious intergenotypic chimeric hepatitis C virus
    • Yi M, Ma Y, Yates J, Lemon SM. 2007. Compensatory mutations in E1, p7, NS2, and NS3 enhance yields of cell culture-infectious intergenotypic chimeric hepatitis C virus. J. Virol. 81:629-638. http://dx.doi.org/10.1128 /JVI.01890-06.
    • (2007) J. Virol. , vol.81 , pp. 629-638
    • Yi, M.1    Ma, Y.2    Yates, J.3    Lemon, S.M.4
  • 49
    • 84876213842 scopus 로고    scopus 로고
    • The C terminus of NS5A domain II is a key determinant of hepatitisCvirus genome replication, but is not required for virion assembly and release
    • Ross-Thriepland D, Amako Y, Harris M. 2013. The C terminus of NS5A domain II is a key determinant of hepatitisCvirus genome replication, but is not required for virion assembly and release. J. Gen. Virol. 94:1009-1018. http://dx.doi.org/10.1099/vir.0.050633-0.
    • (2013) J. Gen. Virol. , vol.94 , pp. 1009-1018
    • Ross-Thriepland, D.1    Amako, Y.2    Harris, M.3
  • 50
    • 10344221613 scopus 로고    scopus 로고
    • The NS5A protein of hepatitis C virus is a zinc metalloprotein
    • Tellinghuisen TL, Marcotrigiano J, Gorbalenya AE, Rice CM. 2004. The NS5A protein of hepatitis C virus is a zinc metalloprotein. J. Biol. Chem. 279:48576-48587. http://dx.doi.org/10.1074/jbc.M407787200.
    • (2004) J. Biol. Chem. , vol.279 , pp. 48576-48587
    • Tellinghuisen, T.L.1    Marcotrigiano, J.2    Gorbalenya, A.E.3    Rice, C.M.4
  • 51
    • 38349162328 scopus 로고    scopus 로고
    • Identification of residues required for RNA replication in domains II and III of the hepatitis C virus NS5A protein
    • Tellinghuisen TL, Foss KL, Treadaway JC, Rice CM. 2008. Identification of residues required for RNA replication in domains II and III of the hepatitis C virus NS5A protein. J. Virol. 82:1073-1083. http://dx.doi.org /10.1128/JVI.00328-07.
    • (2008) J. Virol. , vol.82 , pp. 1073-1083
    • Tellinghuisen, T.L.1    Foss, K.L.2    Treadaway, J.C.3    Rice, C.M.4
  • 52
    • 78650062692 scopus 로고    scopus 로고
    • Hepatitis C virus NS2 protein serves as a scaffold for virus assembly by interacting with both structural and nonstructural proteins
    • Ma Y, Anantpadma M, Timpe JM, Shanmugam S, Singh SM, Lemon SM, Yi M. 2011. Hepatitis C virus NS2 protein serves as a scaffold for virus assembly by interacting with both structural and nonstructural proteins. J. Virol. 85:86-97. http://dx.doi.org/10.1128/JVI.01070-10.
    • (2011) J. Virol. , vol.85 , pp. 86-97
    • Ma, Y.1    Anantpadma, M.2    Timpe, J.M.3    Shanmugam, S.4    Singh, S.M.5    Lemon, S.M.6    Yi, M.7
  • 53
    • 84869232160 scopus 로고    scopus 로고
    • Suppression of viral RNA binding and the assembly of infectious hepatitis C virus particles in vitro by cyclophilin inhibitors
    • Nag A, Robotham JM, Tang H. 2012. Suppression of viral RNA binding and the assembly of infectious hepatitis C virus particles in vitro by cyclophilin inhibitors. J. Virol. 86:12616-12624. http://dx.doi.org/10.1128/JVI .01351-12.
    • (2012) J. Virol. , vol.86 , pp. 12616-12624
    • Nag, A.1    Robotham, J.M.2    Tang, H.3
  • 54
    • 11144227045 scopus 로고    scopus 로고
    • Efficient rescue of hepatitis C virus RNA replication by trans-complementation with nonstructural protein 5A
    • Appel N, Herian U, Bartenschlager R. 2005. Efficient rescue of hepatitis C virus RNA replication by trans-complementation with nonstructural protein 5A. J. Virol. 79:896-909. http://dx.doi.org/10.1128/JVI.79.2.896-909.2005.
    • (2005) J. Virol. , vol.79 , pp. 896-909
    • Appel, N.1    Herian, U.2    Bartenschlager, R.3
  • 55
    • 6344289242 scopus 로고    scopus 로고
    • Genetic interactions between hepatitis C virus replicons
    • Evans MJ, Rice CM, Goff SP. 2004. Genetic interactions between hepatitis C virus replicons. J. Virol. 78:12085-12089. http://dx.doi.org/10.1128 /JVI.78.21.12085-12089.2004.
    • (2004) J. Virol. , vol.78 , pp. 12085-12089
    • Evans, M.J.1    Rice, C.M.2    Goff, S.P.3
  • 56
    • 84855272666 scopus 로고    scopus 로고
    • Increasing rate of cleavage at boundary between non-structural proteins 4B and 5A inhibits replication of hepatitis C virus
    • Herod MR, Jones DM, McLauchlan J, McCormick CJ. 2012. Increasing rate of cleavage at boundary between non-structural proteins 4B and 5A inhibits replication of hepatitis C virus. J. Biol. Chem. 287:568-580. http: //dx.doi.org/10.1074/jbc.M111.311407.
    • (2012) J. Biol. Chem. , vol.287 , pp. 568-580
    • Herod, M.R.1    Jones, D.M.2    McLauchlan, J.3    McCormick, C.J.4
  • 57
    • 70049096419 scopus 로고    scopus 로고
    • Essential role of cyclophilin A for hepatitis C virus replication and virus production and possible link to polyprotein cleavage kinetics
    • Kaul A, Stauffer S, Berger C, Pertel T, Schmitt J, Kallis S, Zayas M, Lohmann V, Luban J, Bartenschlager R. 2009. Essential role of cyclophilin A for hepatitis C virus replication and virus production and possible link to polyprotein cleavage kinetics. PLoS Pathog. 5:e1000546. http://dx .doi.org/10.1371/journal.ppat.1000546.
    • (2009) PLoS Pathog. , vol.5
    • Kaul, A.1    Stauffer, S.2    Berger, C.3    Pertel, T.4    Schmitt, J.5    Kallis, S.6    Zayas, M.7    Lohmann, V.8    Luban, J.9    Bartenschlager, R.10
  • 58
    • 0346688650 scopus 로고    scopus 로고
    • Conserved C-terminal threonine of hepatitis C virus NS3 regulates autoproteolysis and prevents product inhibition
    • Wang W, Lahser FC, Yi M, Wright-Minogue J, Xia E, Weber PC, Lemon SM, Malcolm BA. 2004. Conserved C-terminal threonine of hepatitis C virus NS3 regulates autoproteolysis and prevents product inhibition. J. Virol. 78:700-709. http://dx.doi.org/10.1128/JVI.78.2.700-709 .2004.
    • (2004) J. Virol. , vol.78 , pp. 700-709
    • Wang, W.1    Lahser, F.C.2    Yi, M.3    Wright-Minogue, J.4    Xia, E.5    Weber, P.C.6    Lemon, S.M.7    Malcolm, B.A.8
  • 59
    • 3342914098 scopus 로고    scopus 로고
    • Dominant negative effect of wild-type NS5A on NS5A-adapted subgenomic hepatitis C virus RNA replicon
    • Graziani R, Paonessa G. 2004. Dominant negative effect of wild-type NS5A on NS5A-adapted subgenomic hepatitis C virus RNA replicon. J. Gen. Virol. 85:1867-1875. http://dx.doi.org/10.1099/vir.0.80006-0.
    • (2004) J. Gen. Virol. , vol.85 , pp. 1867-1875
    • Graziani, R.1    Paonessa, G.2
  • 60
    • 30644460414 scopus 로고    scopus 로고
    • Trans-complementation of HCV replication by non-structural protein 5A
    • Tong X, Malcolm BA. 2006. Trans-complementation of HCV replication by non-structural protein 5A. Virus Res. 115:122-130. http://dx.doi.org /10.1016/j.virusres.2005.07.012.
    • (2006) Virus Res. , vol.115 , pp. 122-130
    • Tong, X.1    Malcolm, B.A.2
  • 61
    • 0032837572 scopus 로고    scopus 로고
    • Modulation of hepatitis C virus NS5A hyperphosphorylation by nonstructural proteins NS3, NS4A, and NS4B
    • Koch JO, Bartenschlager R. 1999. Modulation of hepatitis C virus NS5A hyperphosphorylation by nonstructural proteins NS3, NS4A, and NS4B. J. Virol. 73:7138-7146.
    • (1999) J. Virol. , vol.73 , pp. 7138-7146
    • Koch, J.O.1    Bartenschlager, R.2
  • 62
    • 0032710924 scopus 로고    scopus 로고
    • Hyperphosphorylation of the hepatitis C virus NS5A protein requires an active NS3 protease, NS4A, NS4B, and NS5A encoded on the same polyprotein
    • Neddermann P, Clementi A, De Francesco R. 1999. Hyperphosphorylation of the hepatitis C virus NS5A protein requires an active NS3 protease, NS4A, NS4B, and NS5A encoded on the same polyprotein. J. Virol. 73:9984-9991.
    • (1999) J. Virol. , vol.73 , pp. 9984-9991
    • Neddermann, P.1    Clementi, A.2    De Francesco, R.3
  • 63
    • 84873859727 scopus 로고    scopus 로고
    • Intragenic complementation of hepatitis C virus NS5A RNA replication-defective alleles
    • Fridell RA, Valera L, Qiu D, Kirk MJ, Wang C, Gao M. 2013. Intragenic complementation of hepatitis C virus NS5A RNA replication-defective alleles. J. Virol. 87:2320-2329. http://dx.doi.org/10.1128/JVI.02861-12.
    • (2013) J. Virol. , vol.87 , pp. 2320-2329
    • Fridell, R.A.1    Valera, L.2    Qiu, D.3    Kirk, M.J.4    Wang, C.5    Gao, M.6
  • 65
    • 30344472130 scopus 로고    scopus 로고
    • A link between translation of the hepatitis C virus polyprotein and polymerase function; possible consequences for hyperphosphorylation of NS5A
    • McCormick CJ, Brown D, Griffin S, Challinor L, Rowlands DJ, Harris M. 2006. A link between translation of the hepatitis C virus polyprotein and polymerase function; possible consequences for hyperphosphorylation of NS5A. J. Gen. Virol. 87:93-102. http://dx.doi.org/10.1099/vir.0 .81180-0.
    • (2006) J. Gen. Virol. , vol.87 , pp. 93-102
    • McCormick, C.J.1    Brown, D.2    Griffin, S.3    Challinor, L.4    Rowlands, D.J.5    Harris, M.6
  • 66
    • 27644586455 scopus 로고    scopus 로고
    • Development and characterization of a transient-replication assay for the genotype 2a hepatitis C virus subgenomic replicon
    • Targett-Adams P, McLauchlan J. 2005. Development and characterization of a transient-replication assay for the genotype 2a hepatitis C virus subgenomic replicon. J. Gen. Virol. 86:3075-3080. http://dx.doi.org/10 .1099/vir.0.81334-0.
    • (2005) J. Gen. Virol. , vol.86 , pp. 3075-3080
    • Targett-Adams, P.1    McLauchlan, J.2
  • 67
    • 0345223476 scopus 로고    scopus 로고
    • Efficient replication of the genotype 2a hepatitis C virus subgenomic replicon
    • Kato T, Date T, Miyamoto M, Furusaka A, Tokushige K, Mizokami M, Wakita T. 2003. Efficient replication of the genotype 2a hepatitis C virus subgenomic replicon. Gastroenterology 125:1808-1817. http://dx.doi.org /10.1053/j.gastro.2003.09.023.
    • (2003) Gastroenterology , vol.125 , pp. 1808-1817
    • Kato, T.1    Date, T.2    Miyamoto, M.3    Furusaka, A.4    Tokushige, K.5    Mizokami, M.6    Wakita, T.7
  • 68
    • 65549147626 scopus 로고    scopus 로고
    • Expression of hepatitis C virus (HCV) structural proteins in trans facilitates encapsidation and transmission of HCV subgenomic RNA
    • Adair R, Patel AH, Corless L, Griffin S, Rowlands DJ, McCormick CJ. 2009. Expression of hepatitis C virus (HCV) structural proteins in trans facilitates encapsidation and transmission of HCV subgenomic RNA. J. Gen. Virol. 90:833-842. http://dx.doi.org/10.1099/vir.2008.006049-0.
    • (2009) J. Gen. Virol. , vol.90 , pp. 833-842
    • Adair, R.1    Patel, A.H.2    Corless, L.3    Griffin, S.4    Rowlands, D.J.5    McCormick, C.J.6
  • 69
    • 0030731412 scopus 로고    scopus 로고
    • Efficient gene transfer into various mammalian cells, including non-hepatic cells, by baculovirus vectors
    • Shoji I, Aizaki H, Tani H, Ishii K, Chiba T, Saito I, Miyamura T, Matsuura Y. 1997. Efficient gene transfer into various mammalian cells, including non-hepatic cells, by baculovirus vectors. J. Gen. Virol. 78: 2657-2664.
    • (1997) J. Gen. Virol. , vol.78 , pp. 2657-2664
    • Shoji, I.1    Aizaki, H.2    Tani, H.3    Ishii, K.4    Chiba, T.5    Saito, I.6    Miyamura, T.7    Matsuura, Y.8
  • 70
    • 0035032237 scopus 로고    scopus 로고
    • Enhancement of hepatitis C virus RNA replication by cell culture-adaptive mutations
    • Krieger N, Lohmann V, Bartenschlager R. 2001. Enhancement of hepatitis C virus RNA replication by cell culture-adaptive mutations. J. Virol. 75:4614-4624. http://dx.doi.org/10.1128/JVI.75.10.4614-4624.2001.
    • (2001) J. Virol. , vol.75 , pp. 4614-4624
    • Krieger, N.1    Lohmann, V.2    Bartenschlager, R.3
  • 71
    • 50149109600 scopus 로고    scopus 로고
    • Translation termination reinitiation between open reading frame 1 (ORF1) and ORF2 enables capsid expression in a bovine norovirus without the need for production of viral subgenomic RNA
    • McCormick CJ, Salim O, Lambden PR, Clarke IN. 2008. Translation termination reinitiation between open reading frame 1 (ORF1) and ORF2 enables capsid expression in a bovine norovirus without the need for production of viral subgenomic RNA. J. Virol. 82:8917-8921. http://dx.doi .org/10.1128/JVI.02362-07.
    • (2008) J. Virol. , vol.82 , pp. 8917-8921
    • McCormick, C.J.1    Salim, O.2    Lambden, P.R.3    Clarke, I.N.4
  • 72
    • 3142764760 scopus 로고    scopus 로고
    • Insertion of green fluorescent protein into nonstructural protein 5A allows direct visualization of functional hepatitis C virus replication complexes
    • Moradpour D, Evans MJ, Gosert R, Yuan Z, Blum HE, Goff SP, Lindenbach BD, Rice CM. 2004. Insertion of green fluorescent protein into nonstructural protein 5A allows direct visualization of functional hepatitis C virus replication complexes. J. Virol. 78:7400-7409. http://dx .doi.org/10.1128/JVI.78.14.7400-7409.2004.
    • (2004) J. Virol. , vol.78 , pp. 7400-7409
    • Moradpour, D.1    Evans, M.J.2    Gosert, R.3    Yuan, Z.4    Blum, H.E.5    Goff, S.P.6    Lindenbach, B.D.7    Rice, C.M.8
  • 73
    • 0028290579 scopus 로고
    • Both NS3 and NS4A are required for proteolytic processing of hepatitis C virus nonstructural proteins
    • Failla C, Tomei L, De Francesco R. 1994. Both NS3 and NS4A are required for proteolytic processing of hepatitis C virus nonstructural proteins. J. Virol. 68:3753-3760.
    • (1994) J. Virol. , vol.68 , pp. 3753-3760
    • Failla, C.1    Tomei, L.2    De Francesco, R.3
  • 74
    • 84865286934 scopus 로고    scopus 로고
    • Hepatitis C virus translation preferentially depends on active RNA replication
    • Liu HM, Aizaki H, Machida K, Ou JH, Lai MM. 2012. Hepatitis C virus translation preferentially depends on active RNA replication. PLoS One 7:e43600. http://dx.doi.org/10.1371/journal.pone.0043600.
    • (2012) PLoS One , vol.7
    • Liu, H.M.1    Aizaki, H.2    Machida, K.3    Ou, J.H.4    Lai, M.M.5
  • 75
    • 77956028043 scopus 로고    scopus 로고
    • All three domains of the hepatitis C virus nonstructural NS5A protein contribute to RNA binding
    • Foster TL, Belyaeva T, Stonehouse NJ, Pearson AR, Harris M. 2010. All three domains of the hepatitis C virus nonstructural NS5A protein contribute to RNA binding. J. Virol. 84:9267-9277. http://dx.doi.org/10.1128 /JVI.00616-10.
    • (2010) J. Virol. , vol.84 , pp. 9267-9277
    • Foster, T.L.1    Belyaeva, T.2    Stonehouse, N.J.3    Pearson, A.R.4    Harris, M.5
  • 76
    • 33846781512 scopus 로고    scopus 로고
    • Mobility analysis of an NS5A-GFP fusion protein in cells actively replicating hepatitis C virus subgenomic RNA
    • Jones DM, Gretton SN, McLauchlan J, Targett-Adams P. 2007. Mobility analysis of an NS5A-GFP fusion protein in cells actively replicating hepatitis C virus subgenomic RNA. J. Gen. Virol. 88:470-475. http://dx.doi .org/10.1099/vir.0.82363-0.
    • (2007) J. Gen. Virol. , vol.88 , pp. 470-475
    • Jones, D.M.1    Gretton, S.N.2    McLauchlan, J.3    Targett-Adams, P.4
  • 78
    • 47049115607 scopus 로고    scopus 로고
    • Efficient trans-encapsidation of hepatitis C virus RNAs into infectious virus-like particles
    • Steinmann E, Brohm C, Kallis S, Bartenschlager R, Pietschmann T. 2008. Efficient trans-encapsidation of hepatitis C virus RNAs into infectious virus-like particles. J. Virol. 82:7034-7046. http://dx.doi.org/10 .1128/JVI.00118-08.
    • (2008) J. Virol. , vol.82 , pp. 7034-7046
    • Steinmann, E.1    Brohm, C.2    Kallis, S.3    Bartenschlager, R.4    Pietschmann, T.5
  • 79
    • 0036060095 scopus 로고    scopus 로고
    • Hepatitis C virus NS5A colocalizes with the core protein on lipid droplets and interacts with apolipoproteins
    • Shi ST, Polyak SJ, Tu H, Taylor DR, Gretch DR, Lai MM. 2002. Hepatitis C virus NS5A colocalizes with the core protein on lipid droplets and interacts with apolipoproteins. Virology 292:198-210. http://dx.doi .org/10.1006/viro.2001.1225.
    • (2002) Virology , vol.292 , pp. 198-210
    • Shi, S.T.1    Polyak, S.J.2    Tu, H.3    Taylor, D.R.4    Gretch, D.R.5    Lai, M.M.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.