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Volumn 79, Issue 2, 2005, Pages 896-909

Efficient rescue of hepatitis C virus RNA replication by trans-complementation with nonstructural protein 5A

Author keywords

[No Author keywords available]

Indexed keywords

STRUCTURAL PROTEIN; VIRUS RNA;

EID: 11144227045     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.79.2.896-909.2005     Document Type: Article
Times cited : (83)

References (55)
  • 1
  • 2
    • 11144246127 scopus 로고    scopus 로고
    • Novel insights into hepatitis C virus replication and persistence
    • Bartenschlager, R., M. Frese, and T. Pietschmann. 2004. Novel insights into hepatitis C virus replication and persistence. Adv. Virus Res. 63:71-180.
    • (2004) Adv. Virus Res. , vol.63 , pp. 71-180
    • Bartenschlager, R.1    Frese, M.2    Pietschmann, T.3
  • 3
    • 0028820118 scopus 로고
    • Complex formation between the NS3 serine-type proteinase of the hepatitis C virus and NS4A and its importance for polyprotein maturation
    • Bartenschlager, R., V. Lohmann, T. Wilkinson, and J. O. Koch. 1995. Complex formation between the NS3 serine-type proteinase of the hepatitis C virus and NS4A and its importance for polyprotein maturation. J. Virol. 69:7519-7528.
    • (1995) J. Virol. , vol.69 , pp. 7519-7528
    • Bartenschlager, R.1    Lohmann, V.2    Wilkinson, T.3    Koch, J.O.4
  • 4
    • 0032991560 scopus 로고    scopus 로고
    • Nonhomologous RNA recombination in bovine viral diarrhea virus: Molecular characterization of a variety of subgenomic RNAs isolated during an outbreak of fatal mucosal disease
    • Becher, P., M. Orlich, M. König, and H. J. Thiel. 1999. Nonhomologous RNA recombination in bovine viral diarrhea virus: molecular characterization of a variety of subgenomic RNAs isolated during an outbreak of fatal mucosal disease. J. Virol. 73:5646-5653.
    • (1999) J. Virol. , vol.73 , pp. 5646-5653
    • Becher, P.1    Orlich, M.2    König, M.3    Thiel, H.J.4
  • 5
    • 0030051777 scopus 로고    scopus 로고
    • Identification and properties of the RNA-dependent RNA polymerase of hepatitis C virus
    • Behrens, S. E., L. Tomei, and R. de Francesco. 1996. Identification and properties of the RNA-dependent RNA polymerase of hepatitis C virus. EMBO J. 15:12-22.
    • (1996) EMBO J. , vol.15 , pp. 12-22
    • Behrens, S.E.1    Tomei, L.2    De Francesco, R.3
  • 6
    • 0034623816 scopus 로고    scopus 로고
    • Efficient initiation of HCV RNA replication in cell culture
    • Blight, K. J., A. A. Kolykhalov, and C. M. Rice. 2000. Efficient initiation of HCV RNA replication in cell culture. Science 290:1972-1974.
    • (2000) Science , vol.290 , pp. 1972-1974
    • Blight, K.J.1    Kolykhalov, A.A.2    Rice, C.M.3
  • 7
    • 0037040923 scopus 로고    scopus 로고
    • An amino-terminal amphipathic alpha-helix mediates membrane association of the hepatitis C virus nonstructural protein 5A
    • Brass, V., E. Bieck, R. Montserret, B. Wölk, J. A. Hellings, H. E. Blum, F. Penin, and D. Moradpour. 2002. An amino-terminal amphipathic alpha-helix mediates membrane association of the hepatitis C virus nonstructural protein 5A. J. Biol. Chem. 277:8130-8139.
    • (2002) J. Biol. Chem. , vol.277 , pp. 8130-8139
    • Brass, V.1    Bieck, E.2    Montserret, R.3    Wölk, B.4    Hellings, J.A.5    Blum, H.E.6    Penin, F.7    Moradpour, D.8
  • 8
    • 0023277545 scopus 로고
    • Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction
    • Chomczynski, P., and N. Sacchi. 1987. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal. Biochem. 162:156-159.
    • (1987) Anal. Biochem. , vol.162 , pp. 156-159
    • Chomczynski, P.1    Sacchi, N.2
  • 9
    • 0001258874 scopus 로고    scopus 로고
    • Nonstructural protein 5A of hepatitis C virus inhibits the function of karyopherin β3
    • Chung, K. M., J. Lee, J. E. Kim, O. K. Song, S. Cho, J. Lim, M. Seedorf, B. Hahm, and S. K. Jang. 2000. Nonstructural protein 5A of hepatitis C virus inhibits the function of karyopherin β3. J. Virol. 74:5233-5241.
    • (2000) J. Virol. , vol.74 , pp. 5233-5241
    • Chung, K.M.1    Lee, J.2    Kim, J.E.3    Song, O.K.4    Cho, S.5    Lim, J.6    Seedorf, M.7    Hahm, B.8    Jang, S.K.9
  • 12
    • 0036100578 scopus 로고    scopus 로고
    • Expression of hepatitis C virus proteins induces distinct membrane alterations including a candidate viral replication complex
    • Egger, D., B. Wölk, R. Gosert, L. Bianchi, H. E. Blum, D. Moradpour, and K. Bienz. 2002. Expression of hepatitis C virus proteins induces distinct membrane alterations including a candidate viral replication complex. J. Virol. 76:5974-5984.
    • (2002) J. Virol. , vol.76 , pp. 5974-5984
    • Egger, D.1    Wölk, B.2    Gosert, R.3    Bianchi, L.4    Blum, H.E.5    Moradpour, D.6    Bienz, K.7
  • 13
    • 0038415985 scopus 로고    scopus 로고
    • Amphipathic helix-dependent localization of NS5A mediates hepatitis C virus RNA replication
    • Elazar, M., K. H. Cheong, P. Liu, H. B. Greenberg, C. M. Rice, and J. S. Glenn. 2003. Amphipathic helix-dependent localization of NS5A mediates hepatitis C virus RNA replication. J. Virol. 77:6055-6061.
    • (2003) J. Virol. , vol.77 , pp. 6055-6061
    • Elazar, M.1    Cheong, K.H.2    Liu, P.3    Greenberg, H.B.4    Rice, C.M.5    Glenn, J.S.6
  • 14
    • 0028290579 scopus 로고
    • Both NS3 and NS4A are required for proteolytic processing of hepatitis C virus nonstructural proteins
    • Failla, C., L. Tomei, and R. de Francesco. 1994. Both NS3 and NS4A are required for proteolytic processing of hepatitis C virus nonstructural proteins. J. Virol. 68:3753-3760.
    • (1994) J. Virol. , vol.68 , pp. 3753-3760
    • Failla, C.1    Tomei, L.2    De Francesco, R.3
  • 15
    • 10644226734 scopus 로고    scopus 로고
    • A kissingloop interaction in the 3′ end of the hepatitis C virus genome essential for RNA replication
    • Friebe, P., J. Boudet, J. P. Simorre, and R. Bartenschlager. 2005. A kissingloop interaction in the 3′ end of the hepatitis C virus genome essential for RNA replication. J. Virol. 79:380-392.
    • (2005) J. Virol. , vol.79 , pp. 380-392
    • Friebe, P.1    Boudet, J.2    Simorre, J.P.3    Bartenschlager, R.4
  • 16
    • 0343924357 scopus 로고    scopus 로고
    • Evidence that hepatitis C virus resistance to interferon is mediated through repression of the PKR protein kinase by the nonstructural 5A protein
    • Gale, M. J., M. J. Korth, N. M. Tang, S. L. Tan, D. A. Hopkins, T. E. Dever, S. J. Polyak, D. R. Gretch, and M. G. Katze. 1997. Evidence that hepatitis C virus resistance to interferon is mediated through repression of the PKR protein kinase by the nonstructural 5A protein. Virology 230:217-227.
    • (1997) Virology , vol.230 , pp. 217-227
    • Gale, M.J.1    Korth, M.J.2    Tang, N.M.3    Tan, S.L.4    Hopkins, D.A.5    Dever, T.E.6    Polyak, S.J.7    Gretch, D.R.8    Katze, M.G.9
  • 17
    • 2642518680 scopus 로고    scopus 로고
    • RNA recombination in vivo in the absence of viral replication
    • a. Gallei, A., A. Pankraz, H.-J. Thiel, and P. Becher. 2004. RNA recombination in vivo in the absence of viral replication. J. Virol. 78:6271-6281.
    • (2004) J. Virol. , vol.78 , pp. 6271-6281
    • Gallei, A.1    Pankraz, A.2    Thiel, H.-J.3    Becher, P.4
  • 18
    • 1842457783 scopus 로고    scopus 로고
    • Interactions between viral nonstructural proteins and host protein hVAP-33 mediate the formation of hepatitis C virus RNA replication complex on lipid raft
    • Gao, L., H. Aizaki, J. W. He, and M. M. Lai. 2004. Interactions between viral nonstructural proteins and host protein hVAP-33 mediate the formation of hepatitis C virus RNA replication complex on lipid raft. J. Virol. 78:3480-3488.
    • (2004) J. Virol. , vol.78 , pp. 3480-3488
    • Gao, L.1    Aizaki, H.2    He, J.W.3    Lai, M.M.4
  • 19
    • 0034629092 scopus 로고    scopus 로고
    • Hepatitis C virus NS5A protein modulates transcription through a novel cellular transcription factor SRCAP
    • Ghosh, A. K., M. Majumder, R. Steele, P. Yaciuk, J. Chrivia, R. Ray, and R. B. Ray. 2000. Hepatitis C virus NS5A protein modulates transcription through a novel cellular transcription factor SRCAP. J. Biol. Chem. 275:7184-7188.
    • (2000) J. Biol. Chem. , vol.275 , pp. 7184-7188
    • Ghosh, A.K.1    Majumder, M.2    Steele, R.3    Yaciuk, P.4    Chrivia, J.5    Ray, R.6    Ray, R.B.7
  • 21
    • 0345144016 scopus 로고    scopus 로고
    • Identification of the hepatitis C virus RNA replication complex in Huh-7 cells harboring subgenomic replicons
    • Gosert, R., D. Egger, V. Lohmann, R. Bartenschlager, H. E. Blum, K. Bienz, and D. Moradpour. 2003. Identification of the hepatitis C virus RNA replication complex in Huh-7 cells harboring subgenomic replicons. J. Virol. 77:5487-5492.
    • (2003) J. Virol. , vol.77 , pp. 5487-5492
    • Gosert, R.1    Egger, D.2    Lohmann, V.3    Bartenschlager, R.4    Blum, H.E.5    Bienz, K.6    Moradpour, D.7
  • 22
    • 0027414062 scopus 로고
    • Characterization of the hepatitis C virus-encoded serine proteinase: Determination of proteinase-dependent polyprotein cleavage sites
    • Grakoui, A., D. W. McCourt, C. Wychowski, S. M. Feinstone, and C. M. Rice. 1993. Characterization of the hepatitis C virus-encoded serine proteinase: determination of proteinase-dependent polyprotein cleavage sites. J. Virol. 67:2832-2843.
    • (1993) J. Virol. , vol.67 , pp. 2832-2843
    • Grakoui, A.1    McCourt, D.W.2    Wychowski, C.3    Feinstone, S.M.4    Rice, C.M.5
  • 23
    • 0034872308 scopus 로고    scopus 로고
    • Genetic analysis of the pestivirus nonstructural coding region: Defects in the NS5A unit can be complemented in trans
    • Grassmann, C. W., O. Isken, N. Tautz, and S. E. Behrens. 2001. Genetic analysis of the pestivirus nonstructural coding region: defects in the NS5A unit can be complemented in trans. J. Virol. 75:7791-7802.
    • (2001) J. Virol. , vol.75 , pp. 7791-7802
    • Grassmann, C.W.1    Isken, O.2    Tautz, N.3    Behrens, S.E.4
  • 24
    • 3342914098 scopus 로고    scopus 로고
    • Dominant negative effect of wild-type NS5A on NS5A-adapted subgenomic hepatitis C virus RNA replicon
    • Graziani, R., and G. Paonessa. 2004. Dominant negative effect of wild-type NS5A on NS5A-adapted subgenomic hepatitis C virus RNA replicon. J. Gen. Virol. 85:1867-1875.
    • (2004) J. Gen. Virol. , vol.85 , pp. 1867-1875
    • Graziani, R.1    Paonessa, G.2
  • 25
    • 0001601499 scopus 로고
    • NTPase activity of hepatitis C virus NS3 protein expressed in insect cells
    • Gwack, Y., D. W. Kim, J. H. Man, and J. Choe. 1995. NTPase activity of hepatitis C virus NS3 protein expressed in insect cells. Molecules Cells. 5:171-175.
    • (1995) Molecules Cells , vol.5 , pp. 171-175
    • Gwack, Y.1    Kim, D.W.2    Man, J.H.3    Choe, J.4
  • 26
    • 0024520745 scopus 로고
    • Site-directed mutagenesis by overlap extension using the polymerase chain reaction
    • Ho, S. N., H. D. Hunt, R. M. Horton, J. K. Pullen, and L. R. Pease. 1989. Site-directed mutagenesis by overlap extension using the polymerase chain reaction. Gene 77:51-59.
    • (1989) Gene , vol.77 , pp. 51-59
    • Ho, S.N.1    Hunt, H.D.2    Horton, R.M.3    Pullen, J.K.4    Pease, L.R.5
  • 27
    • 3342985091 scopus 로고    scopus 로고
    • Full-length open reading frame of a recombinant hepatitis C virus strain from St Petersburg: Proposed mechanism for its formation
    • Kalinina, O., H. Norder, and L. O. Magnius. 2004. Full-length open reading frame of a recombinant hepatitis C virus strain from St Petersburg: proposed mechanism for its formation. J. Gen. Virol. 85:1853-1857.
    • (2004) J. Gen. Virol. , vol.85 , pp. 1853-1857
    • Kalinina, O.1    Norder, H.2    Magnius, L.O.3
  • 28
    • 0036196640 scopus 로고    scopus 로고
    • A natural intergenotypic recombinant of hepatitis C virus identified in St. Petersburg
    • Kalinina, O., H. Norder, S. Mukomolov, and L. O. Magnius. 2002. A natural intergenotypic recombinant of hepatitis C virus identified in St. Petersburg. J. Virol. 76:4034-4043.
    • (2002) J. Virol. , vol.76 , pp. 4034-4043
    • Kalinina, O.1    Norder, H.2    Mukomolov, S.3    Magnius, L.O.4
  • 30
    • 0031870247 scopus 로고    scopus 로고
    • trans-Complementation of flavivirus RNA polymerase gene NS5 by using Kunjin virus replicon-expressing BHK cells
    • Khromykh, A. A., M. T. Kenney, and E. G. Westaway. 1998. trans-complementation of flavivirus RNA polymerase gene NS5 by using Kunjin virus replicon-expressing BHK cells. J. Virol. 72:7270-7279.
    • (1998) J. Virol. , vol.72 , pp. 7270-7279
    • Khromykh, A.A.1    Kenney, M.T.2    Westaway, E.G.3
  • 31
    • 0032708941 scopus 로고    scopus 로고
    • Efficient trans-complementation of the flavivirus kunjin NS5 protein but not of the NS1 protein requires its coexpression with other components of the viral replicase
    • Khromykh, A. A., P. L. Sedlak, K. J. Guyatt, R. A. Hall, and E. G. Westaway. 1999. Efficient trans-complementation of the flavivirus kunjin NS5 protein but not of the NS1 protein requires its coexpression with other components of the viral replicase. J. Virol. 73:10272-10280.
    • (1999) J. Virol. , vol.73 , pp. 10272-10280
    • Khromykh, A.A.1    Sedlak, P.L.2    Guyatt, K.J.3    Hall, R.A.4    Westaway, E.G.5
  • 32
    • 0032829767 scopus 로고    scopus 로고
    • trans-Complementation analysis of the flavivirus Kunjin ns5 gene reveals an essential role for translation of its N-terminal half in RNA replication
    • Khromykh, A. A., P. L. Sedlak, and E. G. Westaway. 1999. trans-complementation analysis of the flavivirus Kunjin ns5 gene reveals an essential role for translation of its N-terminal half in RNA replication. J. Virol. 73:9247-9255.
    • (1999) J. Virol. , vol.73 , pp. 9247-9255
    • Khromykh, A.A.1    Sedlak, P.L.2    Westaway, E.G.3
  • 33
    • 0028817781 scopus 로고
    • C-terminal domain of the hepatitis C virus NS3 protein contains an RNA helicase activity
    • Kim, D. W., Y. Gwack, J. H. Han, and J. Choe. 1995. C-terminal domain of the hepatitis C virus NS3 protein contains an RNA helicase activity. Biochem. Biophys. Res. Commun. 215:160-166.
    • (1995) Biochem. Biophys. Res. Commun. , vol.215 , pp. 160-166
    • Kim, D.W.1    Gwack, Y.2    Han, J.H.3    Choe, J.4
  • 34
    • 0032837572 scopus 로고    scopus 로고
    • Modulation of hepatitis C virus NS5A hyperphosphorylation by nonstructural proteins NS3, NS4A, and NS4B
    • Koch, J. O., and R. Bartenschlager. 1999. Modulation of hepatitis C virus NS5A hyperphosphorylation by nonstructural proteins NS3, NS4A, and NS4B. J. Virol. 73:7138-7146.
    • (1999) J. Virol. , vol.73 , pp. 7138-7146
    • Koch, J.O.1    Bartenschlager, R.2
  • 35
    • 0035032237 scopus 로고    scopus 로고
    • Enhancement of hepatitis C virus RNA replication by cell culture-adaptive mutations
    • Krieger, N., V. Lohmann, and R. Bartenschlager. 2001. Enhancement of hepatitis C virus RNA replication by cell culture-adaptive mutations. J. Virol. 75:4614-4624.
    • (2001) J. Virol. , vol.75 , pp. 4614-4624
    • Krieger, N.1    Lohmann, V.2    Bartenschlager, R.3
  • 36
    • 0037303634 scopus 로고    scopus 로고
    • In vitro RNA replication directed by replicase complexes isolated from the subgenomic replicon cells of hepatitis C virus
    • Lai, V. C., S. Dempsey, J. Y. Lau, Z. Hong, and W. Zhong. 2003. In vitro RNA replication directed by replicase complexes isolated from the subgenomic replicon cells of hepatitis C virus. J. Virol. 77:2295-2300.
    • (2003) J. Virol. , vol.77 , pp. 2295-2300
    • Lai, V.C.1    Dempsey, S.2    Lau, J.Y.3    Hong, Z.4    Zhong, W.5
  • 37
    • 0030774240 scopus 로고    scopus 로고
    • trans-Complementation of yellow fever virus NS1 reveals a role in early RNA replication
    • Lindenbach, B. D., and C. M. Rice. 1997. trans-Complementation of yellow fever virus NS1 reveals a role in early RNA replication. J. Virol. 71:9608-9617.
    • (1997) J. Virol. , vol.71 , pp. 9608-9617
    • Lindenbach, B.D.1    Rice, C.M.2
  • 38
    • 0036839207 scopus 로고    scopus 로고
    • Complementation analysis of the flavivirus Kunjin NS3 and NS5 proteins defines the minimal regions essential for formation of a replication complex and shows a requirement of NS3 in cis for virus assembly
    • Liu, W. J., P. L. Sedlak, N. Kondratieva, and A. A. Khromykh. 2002. Complementation analysis of the flavivirus Kunjin NS3 and NS5 proteins defines the minimal regions essential for formation of a replication complex and shows a requirement of NS3 in cis for virus assembly. J. Virol. 76:10766-10775.
    • (2002) J. Virol. , vol.76 , pp. 10766-10775
    • Liu, W.J.1    Sedlak, P.L.2    Kondratieva, N.3    Khromykh, A.A.4
  • 39
    • 0037369066 scopus 로고    scopus 로고
    • Viral and cellular determinants of hepatitis C virus RNA replication in cell culture
    • Lohmann, V., S. Hoffmann, U. Herian, F. Penin, and R. Bartenschlager. 2003. Viral and cellular determinants of hepatitis C virus RNA replication in cell culture. J. Virol. 77:3007-3019.
    • (2003) J. Virol. , vol.77 , pp. 3007-3019
    • Lohmann, V.1    Hoffmann, S.2    Herian, U.3    Penin, F.4    Bartenschlager, R.5
  • 40
    • 0035157218 scopus 로고    scopus 로고
    • Mutations in hepatitis C virus RNAs conferring cell culture adaptation
    • Lohmann, V., F. Körner, A. Dobierzewska, and R. Bartenschlager. 2001. Mutations in hepatitis C virus RNAs conferring cell culture adaptation. J. Virol. 75:1437-1449.
    • (2001) J. Virol. , vol.75 , pp. 1437-1449
    • Lohmann, V.1    Körner, F.2    Dobierzewska, A.3    Bartenschlager, R.4
  • 41
    • 1842289764 scopus 로고    scopus 로고
    • Biochemical properties of hepatitis C virus NS5B RNA-dependent RNA polymerase and identification of amino acid sequence motifs essential for enzymatic activity
    • Lohmann, V., F. Körner, U. Herian, and R. Bartenschlager. 1997. Biochemical properties of hepatitis C virus NS5B RNA-dependent RNA polymerase and identification of amino acid sequence motifs essential for enzymatic activity. J. Virol. 71:8416-8428.
    • (1997) J. Virol. , vol.71 , pp. 8416-8428
    • Lohmann, V.1    Körner, F.2    Herian, U.3    Bartenschlager, R.4
  • 43
    • 0035148645 scopus 로고    scopus 로고
    • Hepatitis C virus NS5A physically associates with p53 and regulates p21/waf1 gene expression in a p53-dependent manner
    • Majumder, M., A. K. Ghosh, R. Steele, R. Ray, and R. B. Ray. 2001. Hepatitis C virus NS5A physically associates with p53 and regulates p21/waf1 gene expression in a p53-dependent manner. J. Virol. 75:1401-1407.
    • (2001) J. Virol. , vol.75 , pp. 1401-1407
    • Majumder, M.1    Ghosh, A.K.2    Steele, R.3    Ray, R.4    Ray, R.B.5
  • 44
    • 0346118919 scopus 로고    scopus 로고
    • Hepatitis C virus non-structural proteins in the probable membranous compartment function in viral genome replication
    • Miyanari, Y., M. Hijikata, M. Yamaji, M. Hosaka, H. Takahashi, and K. Shimotohno. 2003. Hepatitis C virus non-structural proteins in the probable membranous compartment function in viral genome replication. J. Biol. Chem. 278:50301-50308.
    • (2003) J. Biol. Chem. , vol.278 , pp. 50301-50308
    • Miyanari, Y.1    Hijikata, M.2    Yamaji, M.3    Hosaka, M.4    Takahashi, H.5    Shimotohno, K.6
  • 45
    • 0042733392 scopus 로고    scopus 로고
    • Hepatitis C virus NS5A protein modulates c-Jun N-terminal kinase through interaction with tumor necrosis factor receptor-associated factor 2
    • Park, K. J., S. H. Choi, D. H. Choi, J. M. Park, S. W. Yie, S. Y. Lee, and S. B. Hwang. 2003. Hepatitis C virus NS5A protein modulates c-Jun N-terminal kinase through interaction with tumor necrosis factor receptor-associated factor 2. J. Biol. Chem. 278:30711-30718.
    • (2003) J. Biol. Chem. , vol.278 , pp. 30711-30718
    • Park, K.J.1    Choi, S.H.2    Choi, D.H.3    Park, J.M.4    Yie, S.W.5    Lee, S.Y.6    Hwang, S.B.7
  • 48
    • 0037379425 scopus 로고    scopus 로고
    • Hepatitis C virus RNA replication occurs on a detergent-resistant membrane that cofractionates with caveolin-2
    • Shi, S. T., K. J. Lee, H. Aizaki, S. B. Hwang, and M. M. Lai. 2003. Hepatitis C virus RNA replication occurs on a detergent-resistant membrane that cofractionates with caveolin-2. J. Virol. 77:4160-4168.
    • (2003) J. Virol. , vol.77 , pp. 4160-4168
    • Shi, S.T.1    Lee, K.J.2    Aizaki, H.3    Hwang, S.B.4    Lai, M.M.5
  • 49
    • 0033545996 scopus 로고    scopus 로고
    • NS5A, a nonstructural protein of hepatitis C virus, binds growth factor receptor-bound protein 2 adaptor protein in a Src homology 3 domain/ligand-dependent manner and perturbs mitogenic signaling
    • Tan, S. L., H. Nakao, Y. He, S. Vijaysri, P. Neddermann, B. L. Jacobs, B. J. Mayer, and M. G. Katze. 1999. NS5A, a nonstructural protein of hepatitis C virus, binds growth factor receptor-bound protein 2 adaptor protein in a Src homology 3 domain/ligand-dependent manner and perturbs mitogenic signaling. Proc. Natl. Acad. Sci. USA 96:5533-5538.
    • (1999) Proc. Natl. Acad. Sci. USA , vol.96 , pp. 5533-5538
    • Tan, S.L.1    Nakao, H.2    He, Y.3    Vijaysri, S.4    Neddermann, P.5    Jacobs, B.L.6    Mayer, B.J.7    Katze, M.G.8
  • 50
    • 0028978937 scopus 로고
    • Phosphorylation of hepatitis C virus-encoded nonstructural protein NS5A
    • Tanji, Y., T. Kaneko, S. Satoh, and K. Shimotohno. 1995. Phosphorylation of hepatitis C virus-encoded nonstructural protein NS5A. J. Virol. 69:3980-3986.
    • (1995) J. Virol. , vol.69 , pp. 3980-3986
    • Tanji, Y.1    Kaneko, T.2    Satoh, S.3    Shimotohno, K.4
  • 51
    • 0036345943 scopus 로고    scopus 로고
    • Interaction between hepatitis C virus proteins and host cell factors
    • Tellinghuisen, T. L., and C. M. Rice. 2002. Interaction between hepatitis C virus proteins and host cell factors. Curr. Opin. Microbiol. 5:419-427.
    • (2002) Curr. Opin. Microbiol. , vol.5 , pp. 419-427
    • Tellinghuisen, T.L.1    Rice, C.M.2
  • 52
    • 0029076836 scopus 로고
    • Inefficient complementation activity of poliovirus 2C and 3D proteins for rescue of lethal mutations
    • Teterina, N. L., W. D. Zhou, M. W. Cho, and E. Ehrenfeld. 1995. Inefficient complementation activity of poliovirus 2C and 3D proteins for rescue of lethal mutations. J. Virol. 69:4245-4254.
    • (1995) J. Virol. , vol.69 , pp. 4245-4254
    • Teterina, N.L.1    Zhou, W.D.2    Cho, M.W.3    Ehrenfeld, E.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.