Essential role of cyclophilin A for hepatitis C virus replication and virus production and possible link to polyprotein cleavage kinetics

PLoS Pathogens

Volumn 5, Issue 8, 2009, Pages

  Kaul, Artur ^a   Stauffer, Sarah ^a   Berger, Carola ^a   Pertel, Thomas ^b   Schmitt, Jennifer ^a   Kallis, Stephanie ^a   Lopez, Margarita Zayas ^a   Lohmann, Volker ^a   Luban, Jeremy ^b   Bartenschlager, Ralf ^a  

^a UNIVERSITY OF HEIDELBERG   (Germany)

^b UNIVERSITY OF GENEVA   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLOPHILIN A; CYCLOPHILIN B; CYCLOSPORIN A [3 N METHYL DEXTRO ALANINE 4 N ETHYLVALINE]; ISOMERASE; NONSTRUCTURAL PROTEIN 2; NONSTRUCTURAL PROTEIN 5A; POLYPROTEIN; RNA DIRECTED RNA POLYMERASE; VIRUS RNA; VIRUS PROTEIN;

ANTIVIRAL ACTIVITY; ARTICLE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; DOSE RESPONSE; GENE AMPLIFICATION; GENE MUTATION; GENOME; GENOTYPE; HEPATITIS C VIRUS; HEPATOMA CELL; HUMAN; HUMAN CELL; MICROBIAL KINETICS; NUCLEOTIDE SEQUENCE; PROTEIN CLEAVAGE; REPLICON; RNA REPLICATION; VIRUS REPLICATION; WESTERN BLOTTING; BIOSYNTHESIS; GENE SILENCING; GENETICS; HOST PATHOGEN INTERACTION; METABOLISM; MUTATION; PHYSIOLOGY; TUMOR CELL LINE;

HEPATITIS C VIRUS; RNA VIRUSES;

CELL LINE, TUMOR; CYCLOPHILIN A; GENE SILENCING; HEPACIVIRUS; HOST-PATHOGEN INTERACTIONS; HUMANS; MUTATION; POLYPROTEINS; RNA, VIRAL; VIRAL NONSTRUCTURAL PROTEINS; VIRUS REPLICATION;

EID: 70049096419     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1000546     Document Type: Article

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