Translation termination reinitiation between open reading frame 1 (ORF1) and ORF2 enables capsid expression in a bovine norovirus without the need for production of viral subgenomic RNA

Journal of Virology

Volumn 82, Issue 17, 2008, Pages 8917-8921

  McCormick, Christopher J ^a,b   Salim, Omar ^a   Lambden, Paul R ^a   Clarke, Ian N ^a  

^a UNIVERSITY OF SOUTHAMPTON   (United Kingdom)

^b SOUTHAMPTON GENERAL HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CAPSID PROTEIN; GENOMIC RNA;

ARTICLE; COW; HUMAN; HUMAN CELL; NONHUMAN; NOROVIRUS; OPEN READING FRAME; PRIORITY JOURNAL; PROTEIN EXPRESSION; VIRUS GENOME;

ANIMALS; BACULOVIRIDAE; BASE SEQUENCE; CAPSID; CARCINOMA, HEPATOCELLULAR; CATTLE; CELL LINE, TUMOR; CODON; HUMANS; HYDROGEN BONDING; LIVER NEOPLASMS; LUCIFERASES; LUCIFERASES, RENILLA; MOLECULAR SEQUENCE DATA; NOROVIRUS; OPEN READING FRAMES; PROTEIN BIOSYNTHESIS; RNA, RIBOSOMAL, 18S; RNA, VIRAL;

BOVINAE; MIRIDAE; NOROVIRUS;

EID: 50149109600     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.02362-07     Document Type: Article

References (17)

1. Clarke, I. N., and P. R. Lambden. 1997. The molecular biology of caliciviruses. J. Gen. Virol. 78:291-301.
2. Daughenbaugh, K. F., C. S. Fraser, J. W. Hershey, and M. E. Hardy. 2003. The genome-linked protein VPg of the Norwalk virus binds eIF3, suggesting its role in translation initiation complex recruitment. EMBO J. 22:2852-2859.
3. Goodfellow, I., Y. Chaudhry, I. Gioldasi, A. Gerondopoulos, A. Natoni, L. Labrie, J. F. Laliberte, and L. Roberts. 2005. Calicivirus translation initiation requires an interaction between VPg and eIF 4 E. EMBO Rep. 6:968-972.
4. Herbert, T. P., I. Brierley, and T. D. Brown. 1996. Detection of the ORF3 polypeptide of feline calicivirus in infected cells and evidence for its expression from a single, functionally bicistronic, subgenomic mRNA. J. Gen. Virol. 77:123-127.
5. Herbert, T. P., I. Brierley, and T. D. Brown. 1997. Identification of a protein linked to the genomic and subgenomic mRNAs of feline calicivirus and its role in translation. J. Gen. Virol. 78:1033-1040.
6. Hutson, A. M., R. L. Atmar, and M. K. Festes. 2004. Norovirus disease: changing epidemiology and host susceptibility factors. Trends Microbiol. 12:279-287.
7. Liu, B. L., P. R. Lambden, H. Gunther, P. Otto, M. Elschner, and I. N. Clarke. 1999. Molecular characterization of a bovine enteric calicivirus: relationship to the Norwalk-like viruses. J. Virol. 73:819-825.
8. Luttermann, C., and G. Meyers. 2007. A bipartite sequence motif induces translation reinitiation in feline calicivirus RNA. J. Biol. Chem. 282:7056-7065.
9. McCormick, C. J., L. Challinor, A. Macdonald, D. J. Rowlands, and M. Harris. 2004. Introduction of replication-competent hepatitis C virus transcripts using a tetracycline-regulable baculovirus delivery system. J. Gen. Virol. 85:429-439.
10. McCormick, C. J., D. J. Rowlands, and M. Harris. 2002. Efficient delivery and regulable expression of hepatitis C virus full-length and minigenome constructs in hepatocyte-derived cell lines using baculovirus vectors. J. Gen. Virol. 83:383-394.
11. Meyers, G. 2003. Translation of the minor capsid protein of a calicivirus is initiated by a novel termination-dependent reinitiation mechanism. J. Biol. Chem. 278:34051-34060.
12. Meyers, G. 2007. Characterization of the sequence element directing translation reinitiation in RNA of the calicivirus rabbit hemorrhagic disease virus. J. Virol. 81:9623-9632.
13. Rohayem, J., I. Robel, K. Jager, U. Scheffler, and W. Rudolph. 2006. Protein-primed and de novo initiation of RNA synthesis by norovirus 3Dpol. J. Virol. 80:7060-7069.
14. Vázquez, A. L., J. M. Alonso, and F. Parra. 2000. Mutation analysis of the GDD sequence motif of a calicivirus RNA-dependent RNA polymerase. J. Virol. 74:3888-3891.
15. Ward, V. K., C. J. McCormick, I. N. Clarke, O. Salim, C. E. Wobus, L. B. Thackray, H. W. Virgin, and P. R. Lambden. 2007. Recovery of infectious murine norovirus using pol II-driven expression of full-length cDNA. Proc. Natl. Acad. Sci. USA 104:11050-11055.
16. Wirblich, C., H. J. Thiel, and G. Meyers. 1996. Genetic map of the calicivirus rabbit hemorrhagic disease virus as deduced from in vitro translation studies. J. Virol. 70:7974-7983.
17. Wobus, C. E., S. M. Karst, L. B. Thackray, K. O. Chang, S. V. Sosnovtsev, G. Belliot, A. Krug, J. M. Mackenzie, K. Y. Green, and H. W. Virgin. 2004. Replication of Norovirus in cell culture reveals a tropism for dendritic cells and macrophages. PLoS Biol. 2:e432.