-
1
-
-
42949130180
-
Essential role of domain III of nonstructural protein 5A for hepatitis C virus infectious particle assembly
-
Appel, N., M. Zayas, S. Miller, J. Krijnse-Locker, T. Schaller, P. Friebe, S. Kallis, U. Engel, and R. Bartenschlager. 2008. Essential role of domain III of nonstructural protein 5A for hepatitis C virus infectious particle assembly. PLoS Pathog. 4:e1000035.
-
(2008)
PLoS Pathog.
, vol.4
-
-
Appel, N.1
Zayas, M.2
Miller, S.3
Krijnse-Locker, J.4
Schaller, T.5
Friebe, P.6
Kallis, S.7
Engel, U.8
Bartenschlager, R.9
-
2
-
-
0032798689
-
Specific interaction between the hepatitis C virus NS5B RNA polymerase and the 3′ end of the viral RNA
-
Cheng, J., C. Ming-Fu, and S. C. Chang. 1999. Specific interaction between the hepatitis C virus NS5B RNA polymerase and the 3′ end of the viral RNA. J. Virol. 73:7044-7049.
-
(1999)
J. Virol.
, vol.73
, pp. 7044-7049
-
-
Cheng, J.1
Ming-Fu, C.2
Chang, S.C.3
-
3
-
-
0025968921
-
Genetic organization and diversity of the hepatitis C virus
-
Choo, Q. L., K. H. Richman, J. H. Han, K. Berger, C. Lee, C. Dong, C. Gallegos, D. Coit, R. Medina-Selby, and P. J. Barr. 1991. Genetic organization and diversity of the hepatitis C virus. Proc. Natl. Acad. Sci. U. S. A. 88:2451-2455.
-
(1991)
Proc. Natl. Acad. Sci. U. S. A.
, vol.88
, pp. 2451-2455
-
-
Choo, Q.L.1
Richman, K.H.2
Han, J.H.3
Berger, K.4
Lee, C.5
Dong, C.6
Gallegos, C.7
Coit, D.8
Medina-Selby, R.9
Barr, P.J.10
-
4
-
-
42149113456
-
Hepatitis C virus therapy to date
-
Foster, G., and P. Mathurin. 2008. Hepatitis C virus therapy to date. Antivir. Ther. 13:1-8.
-
(2008)
Antivir. Ther.
, vol.13
, pp. 1-8
-
-
Foster, G.1
Mathurin, P.2
-
5
-
-
10644226734
-
Kissingloop interaction in the 3′ end of the hepatitis C virus genome essential for RNA replication
-
Friebe, P., J. Boudet, J.-P. Simorre, and R. Bartenschlager. 2005. Kissingloop interaction in the 3′ end of the hepatitis C virus genome essential for RNA replication. J. Virol. 79:380-392.
-
(2005)
J. Virol.
, vol.79
, pp. 380-392
-
-
Friebe, P.1
Boudet, J.2
Simorre, J.-P.3
Bartenschlager, R.4
-
6
-
-
62649145466
-
Domain III of non-structural protein 5A from hepatitis C virus is natively unfolded
-
Hanoulle, X., D. Verdegem, A. Badillo, J. M. Wieruszeski, F. Penin, and G. Lippens. 2009. Domain III of non-structural protein 5A from hepatitis C virus is natively unfolded. Biochem. Biophys. Res. Commun. 381:634-638.
-
(2009)
Biochem. Biophys. Res. Commun.
, vol.381
, pp. 634-638
-
-
Hanoulle, X.1
Verdegem, D.2
Badillo, A.3
Wieruszeski, J.M.4
Penin, F.5
Lippens, G.6
-
7
-
-
67649412015
-
Hepatitis C virus NS5A protein is a substrate for the peptidyl-prolyl cis/trans isomerase activity of cyclophilins a and B
-
Hanoulle, X., A. Badillo, J. M. Wieruszeski, D. Verdegem, I. Landrieu, R. Bartenschlager, F. Penin, and G. Lippens. 2009. Hepatitis C virus NS5A protein is a substrate for the peptidyl-prolyl cis/trans isomerase activity of cyclophilins A and B. J. Biol. Chem. 284:13589-13601.
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 13589-13601
-
-
Hanoulle, X.1
Badillo, A.2
Wieruszeski, J.M.3
Verdegem, D.4
Landrieu, I.5
Bartenschlager, R.6
Penin, F.7
Lippens, G.8
-
8
-
-
27744593476
-
Hepatitis C virus nonstructural protein 5A (NS5A) is an RNA-binding protein
-
Huang, L., J. S. D. Hwang, M. R. S. Hargittai, Y. Chen, J. J. Arnold, K. D. Raney, and C. E. Cameron. 2005. Hepatitis C virus nonstructural protein 5A (NS5A) is an RNA-binding protein. J. Biol. Chem. 280:36417-36428.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 36417-36428
-
-
Huang, L.1
Hwang, J.S.D.2
Hargittai, M.R.S.3
Chen, Y.4
Arnold, J.J.5
Raney, K.D.6
Cameron, C.E.7
-
9
-
-
34249664478
-
Phosphorylation of hepatitis C virus NS5A non-structural protein: A new paradigm for phosphorylation-dependent viral RNA replication?
-
Huang, Y., K. Staschke, R. De Francesco, and S. L. Tan. 2007. Phosphorylation of hepatitis C virus NS5A non-structural protein: a new paradigm for phosphorylation-dependent viral RNA replication? Virology 364:1-9.
-
(2007)
Virology
, vol.364
, pp. 1-9
-
-
Huang, Y.1
Staschke, K.2
De Francesco, R.3
Tan, S.L.4
-
10
-
-
67649197727
-
Domain III of NS5A contributes to both RNA replication and assembly of hepatitis C virus particles
-
Hughes, M., S. Griffin, and M. Harris. 2009. Domain III of NS5A contributes to both RNA replication and assembly of hepatitis C virus particles. J. Gen. Virol. 90:1329-1334.
-
(2009)
J. Gen. Virol.
, vol.90
, pp. 1329-1334
-
-
Hughes, M.1
Griffin, S.2
Harris, M.3
-
11
-
-
0036436838
-
Hepatitis C virus-host interactions: The NS5A protein and the interferon/chemokine systems
-
Khabar, K. S. A., and S. J. Polyak. 2002. Hepatitis C virus-host interactions: the NS5A protein and the interferon/chemokine systems. J. Interferon Cytokine Res. 22:1005-1012.
-
(2002)
J. Interferon Cytokine Res.
, vol.22
, pp. 1005-1012
-
-
Khabar, K.S.A.1
Polyak, S.J.2
-
12
-
-
0036291407
-
Domains I and II in the 5′ nontranslated region of the HCV genome are required for RNA replication
-
Kim, Y. K., C. S. Kim, S. H. Lee, and S. K. Jang. 2002. Domains I and II in the 5′ nontranslated region of the HCV genome are required for RNA replication. Biochem. Biophys. Res. Commun. 290:105-112.
-
(2002)
Biochem. Biophys. Res. Commun.
, vol.290
, pp. 105-112
-
-
Kim, Y.K.1
Kim, C.S.2
Lee, S.H.3
Jang, S.K.4
-
13
-
-
0029938477
-
Identification of a highly conserved sequence element at the 3′ terminus of hepatitis C virus genome RNA
-
Kolykhalov, A. A., S. M. Feinstone, and C. M. Rice. 1996. Identification of a highly conserved sequence element at the 3′ terminus of hepatitis C virus genome RNA. J. Virol. 70:3363-3371.
-
(1996)
J. Virol.
, vol.70
, pp. 3363-3371
-
-
Kolykhalov, A.A.1
Feinstone, S.M.2
Rice, C.M.3
-
14
-
-
33748302052
-
Molecular and structural characterization of the domain II of hepatitis C virus non-structural protein 5A
-
Liang, Y., C. B. Kang, and H. S. Yoon. 2006. Molecular and structural characterization of the domain II of hepatitis C virus non-structural protein 5A. Mol. Cells 22:13-20.
-
(2006)
Mol. Cells
, vol.22
, pp. 13-20
-
-
Liang, Y.1
Kang, C.B.2
Yoon, H.S.3
-
15
-
-
35348891616
-
Domain II of nonstructural protein 5A (NS5A) of hepatitis C virus is natively unfolded
-
Liang, Y., H. Ye, C. B. Kang, and H. S. Yoon. 2007. Domain II of nonstructural protein 5A (NS5A) of hepatitis C virus is natively unfolded. Biochemistry 46:11550-11558.
-
(2007)
Biochemistry
, vol.46
, pp. 11550-11558
-
-
Liang, Y.1
Ye, H.2
Kang, C.B.3
Yoon, H.S.4
-
16
-
-
23944476834
-
Unravelling hepatitis C virus replication from genome to function
-
Lindenbach, B. D., and C. M. Rice. 2005. Unravelling hepatitis C virus replication from genome to function. Nature 436:933-938.
-
(2005)
Nature
, vol.436
, pp. 933-938
-
-
Lindenbach, B.D.1
Rice, C.M.2
-
17
-
-
66149115122
-
Crystal structure of a novel dimeric form of NS5A domain I from hepatitis C virus
-
Love, R. A., O. Brodsky, M. J. Hickey, P. A. Wells, and C. Cronin. 2009. Crystal structure of a novel dimeric form of NS5A domain I from hepatitis C virus. J. Virol. 83:4395-4403.
-
(2009)
J. Virol.
, vol.83
, pp. 4395-4403
-
-
Love, R.A.1
Brodsky, O.2
Hickey, M.J.3
Wells, P.A.4
Cronin, C.5
-
18
-
-
1642375622
-
The hepatitis C virus NS5A protein binds to members of the Src family of tyrosine kinases and regulates kinase activity
-
Macdonald, A., K. Crowder, A. Street, C. McCormick, and M. Harris. 2004. The hepatitis C virus NS5A protein binds to members of the Src family of tyrosine kinases and regulates kinase activity. J. Gen. Virol. 85:721-729.
-
(2004)
J. Gen. Virol.
, vol.85
, pp. 721-729
-
-
Macdonald, A.1
Crowder, K.2
Street, A.3
McCormick, C.4
Harris, M.5
-
19
-
-
0038719743
-
The hepatitis C virus non-structural NS5A protein inhibits activating protein-1 function by perturbing ras-ERK pathway signalling
-
Macdonald, A., K. Crowder, A. Street, C. McCormick, K. Saksela, and M. Harris. 2003. The hepatitis C virus non-structural NS5A protein inhibits activating protein-1 function by perturbing ras-ERK pathway signalling. J. Biol. Chem. 278:17775-17784.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 17775-17784
-
-
Macdonald, A.1
Crowder, K.2
Street, A.3
McCormick, C.4
Saksela, K.5
Harris, M.6
-
20
-
-
4544336360
-
Hepatitis C virus NS5A: Tales of a promiscuous protein
-
Macdonald, A., and M. Harris. 2004. Hepatitis C virus NS5A: tales of a promiscuous protein. J. Gen. Virol. 85:2485-2502.
-
(2004)
J. Gen. Virol.
, vol.85
, pp. 2485-2502
-
-
Macdonald, A.1
Harris, M.2
-
21
-
-
20144387095
-
Further studies on hepatitis C virus NS5A-SH3 domain interactions: Identification of residues critical for binding and implications for viral RNA replication and modulation of cell signalling
-
Macdonald, A., S. Mazaleyrat, C. McCormick, A. Street, N. J. Burgoyne, R. M. Jackson, V. Cazeaux, H. Shelton, K. Saksela, and M. Harris. 2005. Further studies on hepatitis C virus NS5A-SH3 domain interactions: identification of residues critical for binding and implications for viral RNA replication and modulation of cell signalling. J. Gen. Virol. 86:1035-1044.
-
(2005)
J. Gen. Virol.
, vol.86
, pp. 1035-1044
-
-
Macdonald, A.1
Mazaleyrat, S.2
McCormick, C.3
Street, A.4
Burgoyne, N.J.5
Jackson, R.M.6
Cazeaux, V.7
Shelton, H.8
Saksela, K.9
Harris, M.10
-
22
-
-
49149113893
-
Interaction of hepatitis C virus nonstructural protein 5A with core protein is critical for the production of infectious virus particles
-
Masaki, T., R. Suzuki, K. Murakami, H. Aizaki, K. Ishii, A. Murayama, T. Date, Y. Matsuura, T. Miyamura, T. Wakita, and T. Suzuki. 2008. Interaction of hepatitis C virus nonstructural protein 5A with core protein is critical for the production of infectious virus particles. J. Virol. 82:7964-7976.
-
(2008)
J. Virol.
, vol.82
, pp. 7964-7976
-
-
Masaki, T.1
Suzuki, R.2
Murakami, K.3
Aizaki, H.4
Ishii, K.5
Murayama, A.6
Date, T.7
Matsuura, Y.8
Miyamura, T.9
Wakita, T.10
Suzuki, T.11
-
23
-
-
0033591465
-
Expanded sequence dependence of thermodynamic parameters improves prediction of RNA secondary structure
-
Mathews, D. H., J. Sabina, M. Zuker, and D. H. Turner. 1999. Expanded sequence dependence of thermodynamic parameters improves prediction of RNA secondary structure. J. Mol. Biol. 288:911-940.
-
(1999)
J. Mol. Biol.
, vol.288
, pp. 911-940
-
-
Mathews, D.H.1
Sabina, J.2
Zuker, M.3
Turner, D.H.4
-
24
-
-
24144438257
-
Function follows form: The structure of the N-terminal domain of HCV NS5A
-
DOI 10.1002/hep.20851
-
Moradpour, D., V. Brass, and F. Penin. 2005. Function follows form: the structure of the N-terminal domain of HCV NS5A. Hepatology 42:732-735. (Pubitemid 41233668)
-
(2005)
Hepatology
, vol.42
, Issue.3
, pp. 732-735
-
-
Moradpour, D.1
Brass, V.2
Penin, F.3
-
26
-
-
0037470586
-
Substrate complexes of hepatitis C virus RNA polymerase (HC-J4): Structural evidence for nucleotide import and de-novo initiation
-
O'Farrell, D., R. Trowbridge, D. Rowlands, and J. Jäger. 2003. Substrate complexes of hepatitis C virus RNA polymerase (HC-J4): structural evidence for nucleotide import and de-novo initiation. J. Mol. Biol. 326:1025-1035.
-
(2003)
J. Mol. Biol.
, vol.326
, pp. 1025-1035
-
-
O'Farrell, D.1
Trowbridge, R.2
Rowlands, D.3
Jäger, J.4
-
27
-
-
4644260669
-
Structure and function of the membrane anchor domain of hepatitis C virus nonstructural protein 5A
-
Penin, F., V. Brass, N. Appel, S. Ramboarina, R. Montserret, D. Ficheux, H. E. Blum, R. Bartenschlager, and D. Moradpour. 2004. Structure and function of the membrane anchor domain of hepatitis C virus nonstructural protein 5A J. Biol. Chem. 279:40835-40843.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 40835-40843
-
-
Penin, F.1
Brass, V.2
Appel, N.3
Ramboarina, S.4
Montserret, R.5
Ficheux, D.6
Blum, H.E.7
Bartenschlager, R.8
Moradpour, D.9
-
28
-
-
85056075588
-
The hepatitis C virus NS5A stimulates NS5B during in vitro RNA synthesis in a template specific manner
-
Quezada, E. M., and C. M. Kane. 2009. The hepatitis C virus NS5A stimulates NS5B during in vitro RNA synthesis in a template specific manner. Open Biochem. J. 3:39-48.
-
(2009)
Open Biochem. J.
, vol.3
, pp. 39-48
-
-
Quezada, E.M.1
Kane, C.M.2
-
29
-
-
0028844509
-
Unique features of internal initiation of hepatitis C virus RNA translation
-
Reynolds, J. E., A. Kaminski, H. J. Kettinen, K. Grace, B. E. Clarke, A. R. Carroll, D. J. Rowlands, and R. J. Jackson. 1995. Unique features of internal initiation of hepatitis C virus RNA translation. EMBO J. 14:6010-6020.
-
(1995)
EMBO J.
, vol.14
, pp. 6010-6020
-
-
Reynolds, J.E.1
Kaminski, A.2
Kettinen, H.J.3
Grace, K.4
Clarke, B.E.5
Carroll, A.R.6
Rowlands, D.J.7
Jackson, R.J.8
-
30
-
-
33847136509
-
Structure and functions of hepatitis C virus proteins: 15 years after
-
Riley, L. W., V. Rehak, and L. Krekulova. 2006. Structure and functions of hepatitis C virus proteins: 15 years after. Folia Microbiol. 51:665-680.
-
(2006)
Folia Microbiol.
, vol.51
, pp. 665-680
-
-
Riley, L.W.1
Rehak, V.2
Krekulova, L.3
-
31
-
-
40149102826
-
Hepatitis C virus NS5A protein binds the SH3 domain of the Fyn tyrosine kinase with high affinity: Mutagenic analysis of residues within the SH3 domain that contribute to the interaction
-
Shelton, H., and M. Harris. 2008. Hepatitis C virus NS5A protein binds the SH3 domain of the Fyn tyrosine kinase with high affinity: mutagenic analysis of residues within the SH3 domain that contribute to the interaction Virol. J. 5:24.
-
(2008)
Virol. J.
, vol.5
, pp. 24
-
-
Shelton, H.1
Harris, M.2
-
32
-
-
0037192863
-
Hepatitis C virus (HCV) NS5A binds RNA-dependent RNA polymerase (RdRP) NS5B and modulates RNA-dependent RNA polymerase activity
-
Shirota, Y., H. Luo, W. Qin, S. Kaneko, T. Yamashita, K. Kobayashi, and S. Murakami. 2002. Hepatitis C virus (HCV) NS5A binds RNA-dependent RNA polymerase (RdRP) NS5B and modulates RNA-dependent RNA polymerase activity. J. Biol. Chem. 277:11149-11155.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 11149-11155
-
-
Shirota, Y.1
Luo, H.2
Qin, W.3
Kaneko, S.4
Yamashita, T.5
Kobayashi, K.6
Murakami, S.7
-
33
-
-
19644393931
-
Structure of the zinc-binding domain of an essential component of the hepatitis C virus replicase
-
Tellinghuisen, T. L., J. Marcotrigiano, and C. M. Rice. 2005. Structure of the zinc-binding domain of an essential component of the hepatitis C virus replicase. Nature 435:374-379.
-
(2005)
Nature
, vol.435
, pp. 374-379
-
-
Tellinghuisen, T.L.1
Marcotrigiano, J.2
Rice, C.M.3
-
34
-
-
38349162328
-
Identification of residues required for RNA replication in domains II and III of the hepatitis C virus NS5A protein
-
Tellinghuisen, T. L., K. L. Foss, J. C. Treadaway, and C. M. Rice. 2008. Identification of residues required for RNA replication in domains II and III of the hepatitis C virus NS5A protein. J. Virol. 82:1073-1083.
-
(2008)
J. Virol.
, vol.82
, pp. 1073-1083
-
-
Tellinghuisen, T.L.1
Foss, K.L.2
Treadaway, J.C.3
Rice, C.M.4
-
35
-
-
42949145532
-
Regulation of hepatitis C virion production via phosphorylation of the NS5A protein
-
Tellinghuisen, T. L., K. L. Foss, and J. Treadaway. 2008. Regulation of hepatitis C virion production via phosphorylation of the NS5A protein. PLoS Pathog. 4:e1000032.
-
(2008)
PLoS Pathog.
, vol.4
-
-
Tellinghuisen, T.L.1
Foss, K.L.2
Treadaway, J.3
-
37
-
-
0037242882
-
Clinical consequences of hepatitis C virus infection
-
Zoulim, F., M. Chevallier, M. Maynard, and C. Trepo. 2003. Clinical consequences of hepatitis C virus infection. Rev. Med. Virol. 13:57-68.
-
(2003)
Rev. Med. Virol.
, vol.13
, pp. 57-68
-
-
Zoulim, F.1
Chevallier, M.2
Maynard, M.3
Trepo, C.4
-
38
-
-
0042121256
-
Mfold web server for nucleic acid folding and hybridization prediction
-
DOI 10.1093/nar/gkg595
-
Zuker, M. 2003. Mfold web server for nucleic acid folding and hybridization prediction. Nucleic Acids Res. 31:3406-3415. (Pubitemid 37442169)
-
(2003)
Nucleic Acids Research
, vol.31
, Issue.13
, pp. 3406-3415
-
-
Zuker, M.1
|