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Volumn 345, Issue 2, 2014, Pages 203-209

Chronic pancreatitis: A path to pancreatic cancer

Author keywords

Acinar to ductal metaplasia; Dedifferentiation; Inflammation; Oxidative stress; Pancreatic cancer; Pancreatitis

Indexed keywords

ACETYLSALICYLIC ACID; ANTIOXIDANT; APRICOXIB; ASCORBIC ACID; CELECOXIB; CURCUMIN; ERLOTINIB; GEMCITABINE; N (2 CYCLOHEXYLOXY 4 NITROPHENYL)METHANESULFONAMIDE; NIMESULIDE; NONSTEROID ANTIINFLAMMATORY AGENT; SULINDAC;

EID: 84896689276     PISSN: 03043835     EISSN: 18727980     Source Type: Journal    
DOI: 10.1016/j.canlet.2013.08.015     Document Type: Review
Times cited : (114)

References (86)
  • 1
    • 0029027780 scopus 로고
    • Developmental biology of the pancreas
    • Slack J.M. Developmental biology of the pancreas. Development 1995, 121:1569-1580.
    • (1995) Development , vol.121 , pp. 1569-1580
    • Slack, J.M.1
  • 2
    • 34247197621 scopus 로고    scopus 로고
    • Chronic pancreatitis: challenges and advances in pathogenesis, genetics, diagnosis, and therapy
    • Witt H., Apte M.V., Keim V., Wilson J.S. Chronic pancreatitis: challenges and advances in pathogenesis, genetics, diagnosis, and therapy. Gastroenterology 2007, 132:1557-1573.
    • (2007) Gastroenterology , vol.132 , pp. 1557-1573
    • Witt, H.1    Apte, M.V.2    Keim, V.3    Wilson, J.S.4
  • 5
    • 84896705173 scopus 로고    scopus 로고
    • Cancer incidence in five continents. Vol. VIII. IARC Scientific Publications
    • Cancer incidence in five continents. Vol. VIII. IARC Scientific Publications, 2002, pp. 1-781.
    • (2002) , pp. 1-781
  • 8
    • 79959952060 scopus 로고    scopus 로고
    • Somatic variation and cancer: therapies lost in the mix
    • Biankin A.V., Hudson T.J. Somatic variation and cancer: therapies lost in the mix. Human Genetics 2011, 130:79-91.
    • (2011) Human Genetics , vol.130 , pp. 79-91
    • Biankin, A.V.1    Hudson, T.J.2
  • 17
    • 79551625078 scopus 로고    scopus 로고
    • Epithelial tissues have varying degrees of susceptibility to Kras(G12D)-initiated tumorigenesis in a mouse model
    • Ray K.C., Bell K.M., Yan J., Gu G., Chung C.H., Washington M.K., Means A.L. Epithelial tissues have varying degrees of susceptibility to Kras(G12D)-initiated tumorigenesis in a mouse model. PloS one 2011, 6:e16786.
    • (2011) PloS one , vol.6
    • Ray, K.C.1    Bell, K.M.2    Yan, J.3    Gu, G.4    Chung, C.H.5    Washington, M.K.6    Means, A.L.7
  • 18
    • 84857055748 scopus 로고    scopus 로고
    • Pancreatic ductal adenocarcinoma and acinar cells: a matter of differentiation and development?
    • Rooman I., Real F.X. Pancreatic ductal adenocarcinoma and acinar cells: a matter of differentiation and development?. Gut 2012, 61:449-458.
    • (2012) Gut , vol.61 , pp. 449-458
    • Rooman, I.1    Real, F.X.2
  • 22
    • 79954513296 scopus 로고    scopus 로고
    • Adult pancreatic acinar cells dedifferentiate to an embryonic progenitor phenotype with concomitant activation of a senescence programme that is present in chronic pancreatitis
    • Pinho A.V., Rooman I., Reichert M., De Medts N., Bouwens L., Rustgi A.K., Real F.X. Adult pancreatic acinar cells dedifferentiate to an embryonic progenitor phenotype with concomitant activation of a senescence programme that is present in chronic pancreatitis. Gut 2011, 60:958-966.
    • (2011) Gut , vol.60 , pp. 958-966
    • Pinho, A.V.1    Rooman, I.2    Reichert, M.3    De Medts, N.4    Bouwens, L.5    Rustgi, A.K.6    Real, F.X.7
  • 23
    • 79954538151 scopus 로고    scopus 로고
    • P53-dependent regulation of growth, epithelial-mesenchymal transition and stemness in normal pancreatic epithelial cells
    • Pinho A.V., Rooman I., Real F.X. P53-dependent regulation of growth, epithelial-mesenchymal transition and stemness in normal pancreatic epithelial cells. Cell Cycle 2011, 10:1312-1321.
    • (2011) Cell Cycle , vol.10 , pp. 1312-1321
    • Pinho, A.V.1    Rooman, I.2    Real, F.X.3
  • 25
    • 0027454943 scopus 로고
    • Transforming growth factor alpha dramatically enhances oncogene-induced carcinogenesis in transgenic mouse pancreas and liver
    • Sandgren E.P., Luetteke N.C., Qiu T.H., Palmiter R.D., Brinster R.L., Lee D.C. Transforming growth factor alpha dramatically enhances oncogene-induced carcinogenesis in transgenic mouse pancreas and liver. Molecular and Cellular Biology 1993, 13:320-330.
    • (1993) Molecular and Cellular Biology , vol.13 , pp. 320-330
    • Sandgren, E.P.1    Luetteke, N.C.2    Qiu, T.H.3    Palmiter, R.D.4    Brinster, R.L.5    Lee, D.C.6
  • 32
    • 55249127320 scopus 로고    scopus 로고
    • Role of oxidative stress in pancreatic inflammation
    • Leung P.S., Chan Y.C. Role of oxidative stress in pancreatic inflammation. Antioxidants and Redox Signaling 2009, 11:135-165.
    • (2009) Antioxidants and Redox Signaling , vol.11 , pp. 135-165
    • Leung, P.S.1    Chan, Y.C.2
  • 33
    • 0036093865 scopus 로고    scopus 로고
    • Inflammation and the development of pancreatic cancer
    • Farrow B., Evers B.M. Inflammation and the development of pancreatic cancer. Surgical Oncology 2002, 10:153-169.
    • (2002) Surgical Oncology , vol.10 , pp. 153-169
    • Farrow, B.1    Evers, B.M.2
  • 45
    • 84871299072 scopus 로고    scopus 로고
    • Nuclear factor-kappaB in pancreatitis: Jack-of-all-trades, but which one is more important?
    • Gukovsky I., Gukovskaya A. Nuclear factor-kappaB in pancreatitis: Jack-of-all-trades, but which one is more important?. Gastroenterology 2013, 144:26-29.
    • (2013) Gastroenterology , vol.144 , pp. 26-29
    • Gukovsky, I.1    Gukovskaya, A.2
  • 48
    • 80051521184 scopus 로고    scopus 로고
    • Lineage tracing evidence for transdifferentiation of acinar to duct cells and plasticity of human pancreas
    • 741 e731-734
    • Houbracken I., de Waele E., Lardon J., Ling Z., Heimberg H., Rooman I., Bouwens L. Lineage tracing evidence for transdifferentiation of acinar to duct cells and plasticity of human pancreas. Gastroenterology 2011, 141:731-741. 741 e731-734.
    • (2011) Gastroenterology , vol.141 , pp. 731-741
    • Houbracken, I.1    de Waele, E.2    Lardon, J.3    Ling, Z.4    Heimberg, H.5    Rooman, I.6    Bouwens, L.7
  • 50
    • 0033911990 scopus 로고    scopus 로고
    • Modulation of rat pancreatic acinoductal transdifferentiation and expression of PDX-1 in vitro
    • Rooman I., Heremans Y., Heimberg H., Bouwens L. Modulation of rat pancreatic acinoductal transdifferentiation and expression of PDX-1 in vitro. Diabetologia 2000, 43:907-914.
    • (2000) Diabetologia , vol.43 , pp. 907-914
    • Rooman, I.1    Heremans, Y.2    Heimberg, H.3    Bouwens, L.4
  • 51
    • 84862147254 scopus 로고    scopus 로고
    • Oncogenic Kras-induced GM-CSF production promotes the development of pancreatic neoplasia
    • Pylayeva-Gupta Y., Lee K.E., Hajdu C.H., Miller G., Bar-Sagi D. Oncogenic Kras-induced GM-CSF production promotes the development of pancreatic neoplasia. Cancer Cell 2012, 21:836-847.
    • (2012) Cancer Cell , vol.21 , pp. 836-847
    • Pylayeva-Gupta, Y.1    Lee, K.E.2    Hajdu, C.H.3    Miller, G.4    Bar-Sagi, D.5
  • 54
    • 84875382554 scopus 로고    scopus 로고
    • Antioxidant intake and pancreatic cancer risk: the Vitamins and Lifestyle (VITAL) Study
    • Han X., Li J., Brasky T.M., Xun P., Stevens J., White E., Gammon M.D., He K. Antioxidant intake and pancreatic cancer risk: the Vitamins and Lifestyle (VITAL) Study. Cancer 2013, 119:1314-1320.
    • (2013) Cancer , vol.119 , pp. 1314-1320
    • Han, X.1    Li, J.2    Brasky, T.M.3    Xun, P.4    Stevens, J.5    White, E.6    Gammon, M.D.7    He, K.8
  • 55
    • 84873407867 scopus 로고    scopus 로고
    • Dietary antioxidants and the aetiology of pancreatic cancer: a cohort study using data from food diaries and biomarkers
    • Banim P.J., Luben R., McTaggart A., Welch A., Wareham N., Khaw K.T., Hart A.R. Dietary antioxidants and the aetiology of pancreatic cancer: a cohort study using data from food diaries and biomarkers. Gut 2012.
    • (2012) Gut
    • Banim, P.J.1    Luben, R.2    McTaggart, A.3    Welch, A.4    Wareham, N.5    Khaw, K.T.6    Hart, A.R.7
  • 57
    • 84874105891 scopus 로고    scopus 로고
    • Involvement of inflammatory factors in pancreatic carcinogenesis and preventive effects of anti-inflammatory agents
    • Takahashi M., Mutoh M., Ishigamori R., Fujii G., Imai T. Involvement of inflammatory factors in pancreatic carcinogenesis and preventive effects of anti-inflammatory agents. Seminars in Immunopathology 2013, 35:203-227.
    • (2013) Seminars in Immunopathology , vol.35 , pp. 203-227
    • Takahashi, M.1    Mutoh, M.2    Ishigamori, R.3    Fujii, G.4    Imai, T.5
  • 58
    • 1542615084 scopus 로고    scopus 로고
    • Celecoxib inhibits vascular endothelial growth factor expression in and reduces angiogenesis and metastasis of human pancreatic cancer via suppression of Sp1 transcription factor activity
    • Wei D., Wang L., He Y., Xiong H.Q., Abbruzzese J.L., Xie K. Celecoxib inhibits vascular endothelial growth factor expression in and reduces angiogenesis and metastasis of human pancreatic cancer via suppression of Sp1 transcription factor activity. Cancer Research 2004, 64:2030-2038.
    • (2004) Cancer Research , vol.64 , pp. 2030-2038
    • Wei, D.1    Wang, L.2    He, Y.3    Xiong, H.Q.4    Abbruzzese, J.L.5    Xie, K.6
  • 61
    • 20444365468 scopus 로고    scopus 로고
    • Nuclear factor kappa B activation is a potential target for preventing pancreatic carcinoma by aspirin
    • Sclabas G.M., Uwagawa T., Schmidt C., Hess K.R., Evans D.B., Abbruzzese J.L., Chiao P.J. Nuclear factor kappa B activation is a potential target for preventing pancreatic carcinoma by aspirin. Cancer 2005, 103:2485-2490.
    • (2005) Cancer , vol.103 , pp. 2485-2490
    • Sclabas, G.M.1    Uwagawa, T.2    Schmidt, C.3    Hess, K.R.4    Evans, D.B.5    Abbruzzese, J.L.6    Chiao, P.J.7
  • 62
    • 77951744260 scopus 로고    scopus 로고
    • The angiotensin-I-converting enzyme inhibitor enalapril and aspirin delay progression of pancreatic intraepithelial neoplasia and cancer formation in a genetically engineered mouse model of pancreatic cancer
    • Fendrich V., Chen N.M., Neef M., Waldmann J., Buchholz M., Feldmann G., Slater E.P., Maitra A., Bartsch D.K. The angiotensin-I-converting enzyme inhibitor enalapril and aspirin delay progression of pancreatic intraepithelial neoplasia and cancer formation in a genetically engineered mouse model of pancreatic cancer. Gut 2010, 59:630-637.
    • (2010) Gut , vol.59 , pp. 630-637
    • Fendrich, V.1    Chen, N.M.2    Neef, M.3    Waldmann, J.4    Buchholz, M.5    Feldmann, G.6    Slater, E.P.7    Maitra, A.8    Bartsch, D.K.9
  • 63
    • 34547613903 scopus 로고    scopus 로고
    • Delayed progression of pancreatic intraepithelial neoplasia in a conditional Kras(G12D) mouse model by a selective cyclooxygenase-2 inhibitor
    • Funahashi H., Satake M., Dawson D., Huynh N.A., Reber H.A., Hines O.J., Eibl G. Delayed progression of pancreatic intraepithelial neoplasia in a conditional Kras(G12D) mouse model by a selective cyclooxygenase-2 inhibitor. Cancer Research 2007, 67:7068-7071.
    • (2007) Cancer Research , vol.67 , pp. 7068-7071
    • Funahashi, H.1    Satake, M.2    Dawson, D.3    Huynh, N.A.4    Reber, H.A.5    Hines, O.J.6    Eibl, G.7
  • 66
    • 78650825618 scopus 로고    scopus 로고
    • Effect of daily aspirin on long-term risk of death due to cancer: analysis of individual patient data from randomised trials
    • Rothwell P.M., Fowkes F.G., Belch J.F., Ogawa H., Warlow C.P., Meade T.W. Effect of daily aspirin on long-term risk of death due to cancer: analysis of individual patient data from randomised trials. Lancet 2011, 377:31-41.
    • (2011) Lancet , vol.377 , pp. 31-41
    • Rothwell, P.M.1    Fowkes, F.G.2    Belch, J.F.3    Ogawa, H.4    Warlow, C.P.5    Meade, T.W.6
  • 69
    • 84896718098 scopus 로고    scopus 로고
    • http://www.clinicaltrials.gov/.
  • 70
    • 84896719128 scopus 로고    scopus 로고
    • Apricot-P: A randomized placebo-controlled phase II study of COX-2 inhibitor apricoxib or placebo in combination with gemcitabine and erlotinib in advanced or metastatic adenocarcinoma of the pancreas
    • Modiano M., Keogh G.P., Manges R., Stella P.J., Milne G., Looper E., Zaknoen S.L. Apricot-P: A randomized placebo-controlled phase II study of COX-2 inhibitor apricoxib or placebo in combination with gemcitabine and erlotinib in advanced or metastatic adenocarcinoma of the pancreas. ASCO Meeting Abstracts 2012, 30:253.
    • (2012) ASCO Meeting Abstracts , vol.30 , pp. 253
    • Modiano, M.1    Keogh, G.P.2    Manges, R.3    Stella, P.J.4    Milne, G.5    Looper, E.6    Zaknoen, S.L.7
  • 71
    • 39149093843 scopus 로고    scopus 로고
    • C.N.A.R. Kurzrock, Curcumin and pancreatic cancer: Phase II clinical trial experience. ASCO Annual Meeting Proceedings vol.
    • N. Dhillon, B.B. Aggarwal, R.A. Newman, R.A. Wolff, A.B. Kunnumakkara, J.L. Abbruzzese, D.S. Hong, L.H. Camacho, C.N.A.R. Kurzrock, Curcumin and pancreatic cancer: Phase II clinical trial experience. ASCO Annual Meeting Proceedings vol. 25, 2007, pp. 4599.
    • (2007) , vol.25 , pp. 4599
    • Dhillon, N.1    Aggarwal, B.B.2    Newman, R.A.3    Wolff, R.A.4    Kunnumakkara, A.B.5    Abbruzzese, J.L.6    Hong, D.S.7    Camacho, L.H.8
  • 73
    • 67649364114 scopus 로고    scopus 로고
    • The role of inflammation in insulitis and beta-cell loss in type 1 diabetes
    • Eizirik D.L., Colli M.L., Ortis F. The role of inflammation in insulitis and beta-cell loss in type 1 diabetes. Nature Reviews. Endocrinology 2009, 5:219-226.
    • (2009) Nature Reviews. Endocrinology , vol.5 , pp. 219-226
    • Eizirik, D.L.1    Colli, M.L.2    Ortis, F.3
  • 74
    • 84873494524 scopus 로고    scopus 로고
    • Beta-cell dedifferentiation and type 2 diabetes
    • Dor Y., Glaser B. Beta-cell dedifferentiation and type 2 diabetes. The New England Journal of Medicine 2013, 368:572-573.
    • (2013) The New England Journal of Medicine , vol.368 , pp. 572-573
    • Dor, Y.1    Glaser, B.2
  • 75
    • 9444242665 scopus 로고    scopus 로고
    • Five stages of evolving beta-cell dysfunction during progression to diabetes
    • Weir G.C., Bonner-Weir S. Five stages of evolving beta-cell dysfunction during progression to diabetes. Diabetes 2004, 53(Suppl 3):S16-21.
    • (2004) Diabetes , vol.53 , Issue.SUPPL 3
    • Weir, G.C.1    Bonner-Weir, S.2
  • 77
    • 78649352788 scopus 로고    scopus 로고
    • Epidemiology of pancreatic cancer: an update
    • Maisonneuve P., Lowenfels A.B. Epidemiology of pancreatic cancer: an update. Digestive Diseases 2010, 28:645-656.
    • (2010) Digestive Diseases , vol.28 , pp. 645-656
    • Maisonneuve, P.1    Lowenfels, A.B.2
  • 80
    • 0022847553 scopus 로고
    • Size and number of nuclei differ in normal and neoplastic acinar cells from rat pancreas
    • Morgan R.G., Schaeffer B.K., Longnecker D.S. Size and number of nuclei differ in normal and neoplastic acinar cells from rat pancreas. Pancreas 1986, 1:37-43.
    • (1986) Pancreas , vol.1 , pp. 37-43
    • Morgan, R.G.1    Schaeffer, B.K.2    Longnecker, D.S.3
  • 81
    • 16444362549 scopus 로고    scopus 로고
    • P53 deficiency exacerbates pleiotropic mitotic defects, changes in nuclearity and polyploidy in transdifferentiating pancreatic acinar cells
    • Sphyris N., Harrison D.J. P53 deficiency exacerbates pleiotropic mitotic defects, changes in nuclearity and polyploidy in transdifferentiating pancreatic acinar cells. Oncogene 2005, 24:2184-2194.
    • (2005) Oncogene , vol.24 , pp. 2184-2194
    • Sphyris, N.1    Harrison, D.J.2
  • 85
    • 84865491667 scopus 로고    scopus 로고
    • Bmi1 is required for regeneration of the exocrine pancreas in mice
    • e821-822
    • Fukuda A., Morris J.P.T., Hebrok M. Bmi1 is required for regeneration of the exocrine pancreas in mice. Gastroenterology 2012, 143:821-831. e821-822.
    • (2012) Gastroenterology , vol.143 , pp. 821-831
    • Fukuda, A.1    Morris, J.P.T.2    Hebrok, M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.