-
1
-
-
0025863346
-
Identification of cooperating oncogenes in Eμ-myc transgenic mice by provirus tagging
-
M. van Lohuizen, S. Verbeek, B. Scheijen Identification of cooperating oncogenes in E mu-myc transgenic mice by provirus tagging Cell 65 1991 737 752 (Pubitemid 121001306)
-
(1991)
Cell
, vol.65
, Issue.5
, pp. 737-752
-
-
Van Lohuizen, M.1
Verbeek, S.2
Scheijen, B.3
Wientjens, E.4
Van Der Gulden, H.5
Berns, A.6
-
2
-
-
0025727771
-
Novel zinc finger gene implicated as myc collaborator by retrovirally accelerated lymphomagenesis in Eμ-myc transgenic mice
-
Y. Haupt, W.S. Alexander, G. Barri Novel zinc finger gene implicated as myc collaborator by retrovirally accelerated lymphomagenesis in E mu-myc transgenic mice Cell 65 1991 753 763 (Pubitemid 121001307)
-
(1991)
Cell
, vol.65
, Issue.5
, pp. 753-763
-
-
Haupt, Y.1
Alexander, W.S.2
Barri, G.3
Klinken, S.P.4
Adams, J.M.5
-
3
-
-
0025773264
-
Sequence similarity between the mammalian bmi-1 proto-oncogene and the Drosophila regulatory genes Psc and Su(z)2
-
M. van Lohuizen, M. Frasch, E. Wientjens Sequence similarity between the mammalian bmi-1 proto-oncogene and the Drosophila regulatory genes Psc and Su(z)2 Nature 353 1991 353 355 (Pubitemid 21912509)
-
(1991)
Nature
, vol.353
, Issue.6342
, pp. 353-355
-
-
Van Lohuizen, M.1
Frasch, M.2
Wientjens, E.3
Berns, A.4
-
4
-
-
70350500219
-
Polycomb group proteins: Navigators of lineage pathways led astray in cancer
-
A.P. Bracken, K. Helin Polycomb group proteins: navigators of lineage pathways led astray in cancer Nat Rev Cancer 9 2009 773 784
-
(2009)
Nat Rev Cancer
, vol.9
, pp. 773-784
-
-
Bracken, A.P.1
Helin, K.2
-
5
-
-
0038349957
-
Bmi-1 is required for maintenance of adult self-renewing haematopoietic stem cells
-
DOI 10.1038/nature01587
-
I.K. Park, D. Qian, M. Kiel Bmi-1 is required for maintenance of adult self-renewing haematopoietic stem cells Nature 423 2003 302 305 (Pubitemid 40852701)
-
(2003)
Nature
, vol.423
, Issue.6937
, pp. 302-305
-
-
Park, I.-K.1
Qian, D.2
Kiel, M.3
Becker, M.W.4
Pihalja, M.5
Weissman, I.L.6
Morrison, S.J.7
Clarke, M.F.8
-
6
-
-
0242667922
-
Bmi-1 dependence distinguishes neural stem cell self-renewal from progenitor proliferation
-
DOI 10.1038/nature02060
-
A.V. Molofsky, R. Pardal, T. Iwashita Bmi-1 dependence distinguishes neural stem cell self-renewal from progenitor proliferation Nature 425 2003 962 967 (Pubitemid 37376927)
-
(2003)
Nature
, vol.425
, Issue.6961
, pp. 962-967
-
-
Molofsky, A.V.1
Pardal, R.2
Iwashita, T.3
Park, I.-K.4
Clarke, M.F.5
Morrison, S.J.6
-
7
-
-
33745728170
-
Hedgehog signaling and Bmi-1 regulate self-renewal of normal and malignant human mammary stem cells
-
S. Liu, G. Dontu, I.D. Mantle Hedgehog signaling and Bmi-1 regulate self-renewal of normal and malignant human mammary stem cells Cancer Res 66 2006 6063 6071
-
(2006)
Cancer Res
, vol.66
, pp. 6063-6071
-
-
Liu, S.1
Dontu, G.2
Mantle, I.D.3
-
8
-
-
78649669021
-
Bmi-1 is a crucial regulator of prostate stem cell self-renewal and malignant transformation
-
R.U. Lukacs, S. Memarzadeh, H. Wu Bmi-1 is a crucial regulator of prostate stem cell self-renewal and malignant transformation Cell Stem Cell 7 2010 682 693
-
(2010)
Cell Stem Cell
, vol.7
, pp. 682-693
-
-
Lukacs, R.U.1
Memarzadeh, S.2
Wu, H.3
-
9
-
-
0037673984
-
Bmi-1 determines the proliferative capacity of normal and leukaemic stem cells
-
DOI 10.1038/nature01572
-
J. Lessard, G. Sauvageau Bmi-1 determines the proliferative capacity of normal and leukaemic stem cells Nature 423 2003 255 260 (Pubitemid 40852690)
-
(2003)
Nature
, vol.423
, Issue.6937
, pp. 255-260
-
-
Lessard, J.1
Sauvageau, G.2
-
10
-
-
50149092414
-
Bmi1 is critical for lung tumorigenesis and bronchioalveolar stem cell expansion
-
J.S. Dovey, S.J. Zacharek, C.F. Kim Bmi1 is critical for lung tumorigenesis and bronchioalveolar stem cell expansion Proc Natl Acad Sci U S A 105 2008 11857 11862
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 11857-11862
-
-
Dovey, J.S.1
Zacharek, S.J.2
Kim, C.F.3
-
11
-
-
1342289563
-
Bmi1, stem cells, and senescence regulation
-
DOI 10.1172/JCI200420800
-
I.K. Park, S.J. Morrison, M.F. Clarke Bmi1, stem cells, and senescence regulation J Clin Invest 113 2004 175 179 (Pubitemid 38544200)
-
(2004)
Journal of Clinical Investigation
, vol.113
, Issue.2
, pp. 175-179
-
-
Park, I.-K.1
Morrison, S.J.2
Clarke, M.F.3
-
12
-
-
15744400264
-
Recapitulation of elements of embryonic development in adult mouse pancreatic regeneration
-
DOI 10.1053/j.gastro.2004.12.008
-
J.N. Jensen, E. Cameron, M.V. Garay Recapitulation of elements of embryonic development in adult mouse pancreatic regeneration Gastroenterology 128 2005 728 741 (Pubitemid 40585375)
-
(2005)
Gastroenterology
, vol.128
, Issue.3
, pp. 728-741
-
-
Jensen, J.N.1
Cameron, E.2
Garay, M.V.R.3
Starkey, T.W.4
Gianani, R.5
Jensen, J.6
-
13
-
-
76649105065
-
Beta-catenin blocks Kras-dependent reprogramming of acini into pancreatic cancer precursor lesions in mice
-
J.P. Morris IV, D.A. Cano, S. Sekine Beta-catenin blocks Kras-dependent reprogramming of acini into pancreatic cancer precursor lesions in mice J Clin Invest 120 2010 508 520
-
(2010)
J Clin Invest
, vol.120
, pp. 508-520
-
-
Morris, J.P.I.V.1
Cano, D.A.2
Sekine, S.3
-
14
-
-
38649140167
-
Notch signaling is required for exocrine regeneration after acute pancreatitis
-
J.T. Siveke, C. Lubeseder-Martellato, M. Lee Notch signaling is required for exocrine regeneration after acute pancreatitis Gastroenterology 134 2008 544 555
-
(2008)
Gastroenterology
, vol.134
, pp. 544-555
-
-
Siveke, J.T.1
Lubeseder-Martellato, C.2
Lee, M.3
-
15
-
-
48549095907
-
Hedgehog signaling is required for effective regeneration of exocrine pancreas
-
V. Fendrich, F. Esni, M.V. Garay Hedgehog signaling is required for effective regeneration of exocrine pancreas Gastroenterology 135 2008 621 631
-
(2008)
Gastroenterology
, vol.135
, pp. 621-631
-
-
Fendrich, V.1
Esni, F.2
Garay, M.V.3
-
16
-
-
84863427641
-
Beta-catenin is selectively required for the expansion and regeneration of mature pancreatic acinar cells in mice
-
M.D. Keefe, H. Wang, O.J.P. De La Beta-catenin is selectively required for the expansion and regeneration of mature pancreatic acinar cells in mice Dis Model Mech 2012 Feb 2 [Epub ahead of print]
-
(2012)
Dis Model Mech
-
-
Keefe, M.D.1
Wang, H.2
De La, O.J.P.3
-
17
-
-
67649313759
-
Notch and Kras in pancreatic cancer: At the crossroads of mutation, differentiation and signaling
-
O.J.P. De La, L.C. Murtaugh Notch and Kras in pancreatic cancer: at the crossroads of mutation, differentiation and signaling Cell Cycle 8 2009 1860 1864
-
(2009)
Cell Cycle
, vol.8
, pp. 1860-1864
-
-
De La, O.J.P.1
Murtaugh, L.C.2
-
18
-
-
66349132211
-
Bmi1 lineage tracing identifies a self-renewing pancreatic acinar cell subpopulation capable of maintaining pancreatic organ homeostasis
-
E. Sangiorgi, M.R. Capecchi Bmi1 lineage tracing identifies a self-renewing pancreatic acinar cell subpopulation capable of maintaining pancreatic organ homeostasis Proc Natl Acad Sci U S A 106 2009 7101 7106
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 7101-7106
-
-
Sangiorgi, E.1
Capecchi, M.R.2
-
19
-
-
70349158747
-
The epigenetic regulators Bmi1 and Ring1B are differentially regulated in pancreatitis and pancreatic ductal adenocarcinoma
-
C. Martinez-Romero, I. Rooman, A. Skoudy The epigenetic regulators Bmi1 and Ring1B are differentially regulated in pancreatitis and pancreatic ductal adenocarcinoma J Pathol 219 2009 205 213
-
(2009)
J Pathol
, vol.219
, pp. 205-213
-
-
Martinez-Romero, C.1
Rooman, I.2
Skoudy, A.3
-
20
-
-
65249121864
-
Bmi-1 regulates the Ink4a/Arf locus to control pancreatic beta-cell proliferation
-
S. Dhawan, S.I. Tschen, A. Bhushan Bmi-1 regulates the Ink4a/Arf locus to control pancreatic beta-cell proliferation Genes Dev 23 2009 906 911
-
(2009)
Genes Dev
, vol.23
, pp. 906-911
-
-
Dhawan, S.1
Tschen, S.I.2
Bhushan, A.3
-
21
-
-
34547194433
-
Bmi-1-green fluorescent protein-knock-in mice reveal the dynamic regulation of Bmi-1 expression in normal and leukemic hematopoietic cells
-
DOI 10.1634/stemcells.2006-0229
-
N. Hosen, T. Yamane, M. Muijtjens Bmi-1-green fluorescent protein-knock-in mice reveal the dynamic regulation of bmi-1 expression in normal and leukemic hematopoietic cells Stem Cells 25 2007 1635 1644 (Pubitemid 47121840)
-
(2007)
Stem Cells
, vol.25
, Issue.7
, pp. 1635-1644
-
-
Hosen, N.1
Yamane, T.2
Muijtjens, M.3
Pham, K.4
Clarke, M.F.5
Weissman, I.L.6
-
22
-
-
0032417268
-
The bHLH protein PTF1-p48 is essential for the formation of the exocrine and the correct spatial organization of the endocrine pancreas
-
A. Krapp, M. Knofler, B. Ledermann The bHLH protein PTF1-p48 is essential for the formation of the exocrine and the correct spatial organization of the endocrine pancreas Genes Dev 12 1998 3752 3763 (Pubitemid 29019655)
-
(1998)
Genes and Development
, vol.12
, Issue.23
, pp. 3752-3763
-
-
Krapp, A.1
Knofler, M.2
Ledermann, B.3
Burki, K.4
Berney, C.5
Zoerkler, N.6
Hagenbuchle, O.7
Wellauer, P.K.8
-
23
-
-
0036730427
-
The role of the transcriptional regulator Ptf1a in converting intestinal to pancreatic progenitors
-
DOI 10.1038/ng959
-
Y. Kawaguchi, B. Cooper, M. Gannon The role of the transcriptional regulator Ptf1a in converting intestinal to pancreatic progenitors Nat Genet 32 2002 128 134 (Pubitemid 34977207)
-
(2002)
Nature Genetics
, vol.32
, Issue.1
, pp. 128-134
-
-
Kawaguchi, Y.1
Cooper, B.2
Gannon, M.3
Ray, M.4
MacDonald, R.J.5
Wright, C.V.E.6
-
24
-
-
84924133024
-
The bHLH transcription factor Mist1 is required to maintain exocrine pancreas cell organization and acinar cell identity
-
C.L. Pin, J.M. Rukstalis, C. Johnson The bHLH transcription factor Mist1 is required to maintain exocrine pancreas cell organization and acinar cell identity J Cell Biol 155 2001 519 530 (Pubitemid 34289311)
-
(2001)
Journal of Cell Biology
, vol.155
, Issue.3
, pp. 519-530
-
-
Pin, C.L.1
Michael Rukstalis, J.2
Johnson, C.3
Konieczny, S.F.4
-
25
-
-
0016798054
-
Acute hemorrhagic pancreatitis (massive necrosis) with fat necrosis induced in mice by DL-ethionine fed with a choline-deficient diet
-
B. Lombardi, L.W. Estes, D.S. Longnecker Acute hemorrhagic pancreatitis (massive necrosis) with fat necrosis induced in mice by DL-ethionine fed with a choline-deficient diet Am J Pathol 79 1975 465 480
-
(1975)
Am J Pathol
, vol.79
, pp. 465-480
-
-
Lombardi, B.1
Estes, L.W.2
Longnecker, D.S.3
-
26
-
-
0034101816
-
CD4+ T cells play an important role in acute experimental pancreatitis in mice
-
A. Demols, O. Le Moine, F. Desalle CD4(+ )T cells play an important role in acute experimental pancreatitis in mice Gastroenterology 118 2000 582 590 (Pubitemid 30140857)
-
(2000)
Gastroenterology
, vol.118
, Issue.3
, pp. 582-590
-
-
Demols, A.1
Le Moine, O.2
Desalle, F.3
Quertinmont, E.4
Van Laethem, J.-L.5
Deviere, J.6
-
27
-
-
79953761842
-
Stat3 and MMP7 contribute to pancreatic ductal adenocarcinoma initiation and progression
-
A. Fukuda, S.C. Wang, J.P. Morris IV Stat3 and MMP7 contribute to pancreatic ductal adenocarcinoma initiation and progression Cancer Cell 19 2011 441 455
-
(2011)
Cancer Cell
, vol.19
, pp. 441-455
-
-
Fukuda, A.1
Wang, S.C.2
Morris, J.P.I.V.3
-
28
-
-
84859398141
-
CCL2-induced migration and SOCS3-mediated activation of macrophages are involved in cerulein-induced pancreatitis in mice
-
K. Saeki, T. Kanai, M. Nakano CCL2-induced migration and SOCS3-mediated activation of macrophages are involved in cerulein-induced pancreatitis in mice Gastroenterology 142 2012 1010 1020
-
(2012)
Gastroenterology
, vol.142
, pp. 1010-1020
-
-
Saeki, K.1
Kanai, T.2
Nakano, M.3
-
29
-
-
0028201742
-
Posterior transformation, neurological abnormalities, and severe hematopoietic defects in mice with a targeted deletion of the bmi-1 proto-oncogene
-
N.M. van der Lugt, J. Domen, K. Linders Posterior transformation, neurological abnormalities, and severe hematopoietic defects in mice with a targeted deletion of the bmi-1 proto-oncogene Genes Dev 8 1994 757 769
-
(1994)
Genes Dev
, vol.8
, pp. 757-769
-
-
Van Der Lugt, N.M.1
Domen, J.2
Linders, K.3
-
30
-
-
34147190365
-
Preexisting pancreatic acinar cells contribute to acinar cell, but not islet β cell, regeneration
-
DOI 10.1172/JCI29988
-
B.M. Desai, J. Oliver-Krasinski, D.D. De Leon Preexisting pancreatic acinar cells contribute to acinar cell, but not islet beta cell, regeneration J Clin Invest 117 2007 971 977 (Pubitemid 46556753)
-
(2007)
Journal of Clinical Investigation
, vol.117
, Issue.4
, pp. 971-977
-
-
Desai, B.M.1
Oliver-Krasinski, J.2
De Leon, D.D.3
Farzad, C.4
Hong, N.5
Leach, S.D.6
Stoffers, D.A.7
-
31
-
-
36549077062
-
In Vivo Lineage Tracing Defines the Role of Acinar-to-Ductal Transdifferentiation in Inflammatory Ductal Metaplasia
-
DOI 10.1053/j.gastro.2007.09.009, PII S0016508507016502
-
O. Strobel, Y. Dor, J. Alsina In vivo lineage tracing defines the role of acinar-to-ductal transdifferentiation in inflammatory ductal metaplasia Gastroenterology 133 2007 1999 2009 (Pubitemid 350180811)
-
(2007)
Gastroenterology
, vol.133
, Issue.6
, pp. 1999-2009
-
-
Strobel, O.1
Dor, Y.2
Alsina, J.3
Stirman, A.4
Lauwers, G.5
Trainor, A.6
Castillo, C.F.7
Warshaw, A.L.8
Thayer, S.P.9
-
32
-
-
78651228289
-
Continuous cell supply from a Sox9-expressing progenitor zone in adult liver, exocrine pancreas and intestine
-
K. Furuyama, Y. Kawaguchi, H. Akiyama Continuous cell supply from a Sox9-expressing progenitor zone in adult liver, exocrine pancreas and intestine Nat Genet 43 2010 34 41
-
(2010)
Nat Genet
, vol.43
, pp. 34-41
-
-
Furuyama, K.1
Kawaguchi, Y.2
Akiyama, H.3
-
33
-
-
79951539242
-
Sox9+ ductal cells are multipotent progenitors throughout development but do not produce new endocrine cells in the normal or injured adult pancreas
-
J.L. Kopp, C.L. Dubois, A.E. Schaffer Sox9+ ductal cells are multipotent progenitors throughout development but do not produce new endocrine cells in the normal or injured adult pancreas Development 138 2011 653 665
-
(2011)
Development
, vol.138
, pp. 653-665
-
-
Kopp, J.L.1
Dubois, C.L.2
Schaffer, A.E.3
-
34
-
-
78751515624
-
Lineage tracing reveals the dynamic contribution of Hes1+ cells to the developing and adult pancreas
-
D. Kopinke, M. Brailsford, J.E. Shea Lineage tracing reveals the dynamic contribution of Hes1+ cells to the developing and adult pancreas Development 138 2011 431 441
-
(2011)
Development
, vol.138
, pp. 431-441
-
-
Kopinke, D.1
Brailsford, M.2
Shea, J.E.3
-
35
-
-
76249094159
-
Isolation and characterization of centroacinar/terminal ductal progenitor cells in adult mouse pancreas
-
M. Rovira, S.G. Scott, A.S. Liss Isolation and characterization of centroacinar/terminal ductal progenitor cells in adult mouse pancreas Proc Natl Acad Sci U S A 107 2010 75 80
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, pp. 75-80
-
-
Rovira, M.1
Scott, S.G.2
Liss, A.S.3
-
36
-
-
58849166901
-
The polycomb group gene Bmi1 regulates antioxidant defenses in neurons by repressing p53 pro-oxidant activity
-
W. Chatoo, M. Abdouh, J. David The polycomb group gene Bmi1 regulates antioxidant defenses in neurons by repressing p53 pro-oxidant activity J Neurosci 29 2009 529 542
-
(2009)
J Neurosci
, vol.29
, pp. 529-542
-
-
Chatoo, W.1
Abdouh, M.2
David, J.3
-
37
-
-
84863252826
-
EZH2 couples pancreatic regeneration to neoplastic progression
-
J. Mallen-St Clair, R. Soydaner-Azeloglu, K.E. Lee EZH2 couples pancreatic regeneration to neoplastic progression Genes Dev 26 2012 439 444
-
(2012)
Genes Dev
, vol.26
, pp. 439-444
-
-
Mallen-St Clair, J.1
Soydaner-Azeloglu, R.2
Lee, K.E.3
-
38
-
-
65249093055
-
Polycomb protein Ezh2 regulates pancreatic beta-cell Ink4a/Arf expression and regeneration in diabetes mellitus
-
H. Chen, X. Gu, I.H. Su Polycomb protein Ezh2 regulates pancreatic beta-cell Ink4a/Arf expression and regeneration in diabetes mellitus Genes Dev 23 2009 975 985
-
(2009)
Genes Dev
, vol.23
, pp. 975-985
-
-
Chen, H.1
Gu, X.2
Su, I.H.3
-
39
-
-
80054857694
-
Dendritic cells promote pancreatic viability in mice with acute pancreatitis
-
A.S. Bedrosian, A.H. Nguyen, M. Hackman Dendritic cells promote pancreatic viability in mice with acute pancreatitis Gastroenterology 141 2011 1915 1926
-
(2011)
Gastroenterology
, vol.141
, pp. 1915-1926
-
-
Bedrosian, A.S.1
Nguyen, A.H.2
Hackman, M.3
-
40
-
-
15744400264
-
Recapitulation of elements of embryonic development in adult mouse pancreatic regeneration
-
DOI 10.1053/j.gastro.2004.12.008
-
J.N. Jensen, E. Cameron, M.V. Garay Recapitulation of elements of embryonic development in adult mouse pancreatic regeneration Gastroenterology 128 2005 728 741 (Pubitemid 40585375)
-
(2005)
Gastroenterology
, vol.128
, Issue.3
, pp. 728-741
-
-
Jensen, J.N.1
Cameron, E.2
Garay, M.V.R.3
Starkey, T.W.4
Gianani, R.5
Jensen, J.6
-
41
-
-
0016798054
-
Acute hemorrhagic pancreatitis (massive necrosis) with fat necrosis induced in mice by DL-ethionine fed with a choline-deficient diet
-
B. Lombardi, L.W. Estes, D.S. Longnecker Acute hemorrhagic pancreatitis (massive necrosis) with fat necrosis induced in mice by DL-ethionine fed with a choline-deficient diet Am J Pathol 79 1975 465 480
-
(1975)
Am J Pathol
, vol.79
, pp. 465-480
-
-
Lombardi, B.1
Estes, L.W.2
Longnecker, D.S.3
-
42
-
-
79953761842
-
Stat3 and MMP7 contribute to pancreatic ductal adenocarcinoma initiation and progression
-
A. Fukuda, S.C. Wang, J.P. Morris IV Stat3 and MMP7 contribute to pancreatic ductal adenocarcinoma initiation and progression Cancer Cell 19 2011 441 455
-
(2011)
Cancer Cell
, vol.19
, pp. 441-455
-
-
Fukuda, A.1
Wang, S.C.2
Morris, J.P.I.V.3
-
43
-
-
24944441782
-
Pancreatic epithelial plasticity mediated by acinar cell transdifferentiation and generation of nestin-positive intermediates
-
DOI 10.1242/dev.01925
-
A.L. Means, I.M. Meszoely, K. Suzuki Pancreatic epithelial plasticity mediated by acinar cell transdifferentiation and generation of nestin-positive intermediates Development 132 2005 3767 3776 (Pubitemid 41301112)
-
(2005)
Development
, vol.132
, Issue.16
, pp. 3767-3776
-
-
Means, A.L.1
Meszoely, I.M.2
Suzuki, K.3
Miyamoto, Y.4
Rustgi, A.K.5
Coffey Jr., R.J.6
Wright, C.V.E.7
Stoffers, D.A.8
Leach, S.D.9
-
44
-
-
10744223624
-
Notch mediates TGFα-induced changes in epithelial differentiation during pancreatic tumorigenesis
-
DOI 10.1016/S1535-6108(03)00140-5
-
Y. Miyamoto, A. Maitra, B. Ghosh Notch mediates TGF alpha-induced changes in epithelial differentiation during pancreatic tumorigenesis Cancer Cell 3 2003 565 576 (Pubitemid 36808651)
-
(2003)
Cancer Cell
, vol.3
, Issue.6
, pp. 565-576
-
-
Miyamoto, Y.1
Maitra, A.2
Ghosh, B.3
Zechner, U.4
Argani, P.5
Iacobuzio-Donahue, C.A.6
Sriuranpong, V.7
Iso, T.8
Meszoely, I.M.9
Wolfe, M.S.10
Hruban, R.H.11
Ball, D.W.12
Schmid, R.M.13
Leach, S.D.14
|