p53 deficiency exacerbates pleiotropic mitotic defects, changes in nuclearity and polyploidy in transdifferentiating pancreatic acinar cells

Oncogene

Volumn 24, Issue 13, 2005, Pages 2184-2194

  Sphyris, Nathalie ^a   Harrison, David J ^a  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

Author keywords

Aneuploidy; Centrosomes; Mitosis; P53; Pancreas acinar ductal transdifferentiation; Polyploidy

Indexed keywords

PROTEIN P53;

ACINAR CELL; ANEUPLOIDY; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL DIFFERENTIATION; CENTROSOME; IMMUNOFLUORESCENCE; MITOSIS; MOUSE; NONHUMAN; PANCREAS TUMOR; PRIORITY JOURNAL; TUMOR SUPPRESSOR GENE; ANIMAL; CELL NUCLEUS; CYTOLOGY; GENE AMPLIFICATION; GENETICS; GENOME; MOUSE MUTANT; PANCREAS; PHYSIOLOGY; PLOIDY; POLYPLOIDY; ULTRASTRUCTURE;

ANIMALS; CELL DIFFERENTIATION; CELL NUCLEUS; CENTROSOME; GENE AMPLIFICATION; GENOME; MICE; MICE, KNOCKOUT; PANCREAS; PLOIDIES; POLYPLOIDY; TUMOR SUPPRESSOR PROTEIN P53;

EID: 16444362549     PISSN: 09509232     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.onc.1208249     Document Type: Article

References (44)

1. Andreassen PR, Lohez OD, Lacroix FB and Margolis RL. (2001). Mol. Biol. Cell, 12, 1315-1328.
2. Arias AE and Bendayan M. (1993). Lab. Invest., 69, 518-530.
3. Bardeesy N and DePinho RA. (2002). Nat. Rev. Cancer, 2, 897-909.
4. Bates S, Ryan KM, Phillips AC and Vousden KH. (1998). Oncogene, 17, 1691-1703.
5. Borel F, Lohez OD, Lacroix FB and Margolis RL. (2002). Proc. Natl. Acad. Sci. USA, 99, 9819-9824.
6. Bottinger EP, Jakubczak JL, Roberts IS, Mumy M, Hemmati P, Bagnall K, Merlino G and Wakefield LM. (1997). EMBO J., 16, 2621-2633.
7. Casenghi M, Mangiacasale R, Tuynder M, Caillet-Fauquet P, Elhajouji A, Lavia P, Mousset S, Kirsch-Volders M and Cundari E. (1999). Exp. Cell Res., 250, 339-350.
8. Clarke AR, Cummings MC and Harrison DJ. (1995). Oncogene, 11, 1913-1920.
9. Daujat S, Neel H and Piette J. (2001). Trends Genet., 17, 459-464.
10. Dazard JE, Piette J, Basset-Seguin N, Blanchard JM and Gandarillas A. (2000). Oncogene, 19, 3693-3705.
11. De Lisle RC and Logsdon CD. (1990). Eur. J. Cell Biol., 51, 64-75.
12. Fukasawa K, Choi T, Kuriyama R, Rulong S and Vande Woude GF. (1996). Science, 271, 1744-1747.
13. Guidotti JE, Bregerie O, Robert A, Debey P, Brechet C and Desdouets C. (2003). J. Biol. Chem., 278, 19095-19101.
14. Hall PA and Lemoine NR. (1992). J. Pathol., 166, 97-103.
15. Haroske G, Giroud F, Reith A and Docking A. (1998). Anal. Cell Pathol., 17, 189-200.
16. Hong FD, Chen J, Donovan S, Schneider N and Nisen PD. (1999). Carcinogenesis, 20, 1161-1168.
17. Hoshi H and Logsdon CD. (1993). Am. J. Physiol., 265, G1177-G1181.
18. Khan SH and Wahl GM. (1998). Cancer Res., 58, 396-401.
19. Kikuchi J, Furukawa Y, Iwase S, Terui Y, Nakamura M, Kitagawa S, Kitagawa M, Komatsu N and Miura Y. (1997). Blood, 89, 3980-3990.
20. Lanni JS and Jacks T. (1998). Mol. Cell. Biol., 18, 1055-1064.
21. Lawlor MA and Rotwein P. (2000). Mol. Cell. Biol., 20, 8983-8995.
22. Lundgren K, Montes de Oca LR, McNeill YB, Emerick EP, Spencer B, Barfield CR, Lozano G, Rosenberg MP and Finlay CA. (1997). Genes Dev., 11, 714-725.
23. Matsumura I, Ishikawa J, Nakajima K, Oritani K, Tomiyama Y, Miyagawa J, Kalo T, Miyazaki H, Matsuzawa Y and Kanakura Y. (1997). Mol. Cell. Biol., 17, 2933-2943.
24. Meraldi P, Honda R and Nigg EA. (2002). EMBO J., 21, 483-492.
25. Nagata Y, Muro Y and Todokoro K. (1997). J. Cell Biol., 139, 449-457.
26. Niculescu III AB, Chen X, Smeets M, Hengst L, Prives C and Reed SI. (1998). Mol. Cell. Biol., 18, 629-643.
27. Ornitz DM, Hammer RE, Messing A, Palmiter RD and Brinster RL. (1987). Science, 238, 188-193.
28. Poluha W, Poluha DK, Chang B, Crosbie NE, Schonhoff CM, Kilpatrick DL and Ross AH. (1996). Mol. Cell. Biol., 16, 1335-1341.
29. Purdie CA, Harrison DJ, Peter A, Dobbie L, White S, Howie SE, Salter DM, Bird CC, Wyllie AH, Hooper ML and Clarke AR. (1994). Oncogene, 9, 603-609.
30. Quaife CJ, Pinkert CA, Ornitz DM, Palmiter RD and Brinster RL. (1987). Cell, 48, 1023-1034.
31. Ramel S, Sanchez CA, Schimke MK, Neshat K, Cross SM, Raskind WH and Reid BJ. (1995). Pancreas, 11, 213-222.
32. Rooney RJ. (2001). Cell Growth Differ., 12, 505-516.
33. Roy L, Coullin P, Vitrat N, Hellio R, Debili N, Weinstein J, Bernheim A and Vainchenker W. (2001). Blood, 97, 2238-2247.
34. Sandgren EP, Quaife CJ, Paulovich AG, Palmiter RD and Brinster RL. (1991). Proc. Natl. Acad. Sci. USA, 88, 93-97.
35. Sato N, Mizumoto K, Nakamura M, Maehara N, Minamishima YA, Nishio S, Nagai E and Tanaka M. (2001). Cancer Genet. Cytogenet., 126, 13-19.
36. Sato N, Mizumoto K, Nakamura M, Nakamura K, Kusumoto M, Niiyama H, Ogawa T and Tanaka M. (1999). Clin. Cancer Res., 5, 963-970.
37. Scarpelli DG, Rao MS and Reddy JK. (1984). Environ. Health Perspect., 56, 217-227.
38. Sluder G and Nordberg JJ. (2004). Curr. Opin. Cell Biol., 16, 49-54.
39. Sphyris N, Logsdon CD and Harrison DJ. (2005). Pancreas, 30, (in press).
40. Tarapore P and Fukasawa K. (2002). Oncogene, 21, 6234-6240.
41. Uetake Y and Sluder G. (2004). J. Cell Biol., 165, 609-615.
42. Vila MR, Lloreta J and Real FX. (1994). Lab Invest., 71, 423-431.
43. Wang J and Walsh K. (1996). Science, 273, 359-361.
44. Wu H, Wade M, Krall L, Grisham J, Xiong Y and Van Dyke T. (1996). Genes Dev., 10, 245-260.