Development of a thyroperoxidase inhibition assay for high-throughput screening

Chemical Research in Toxicology

Volumn 27, Issue 3, 2014, Pages 387-399

  Paul, Katie B ^a   Hedge, Joan M ^a   Rotroff, Daniel M ^a   Hornung, Michael W ^b   Crofton, Kevin M ^a   Simmons, Steven O ^a  

^a U S ENVIRONMENTAL PROTECTION AGENCY   (United States)

^b U S ENVIRONMENTAL PROTECTION AGENCY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 IMIDAZOLIDINETHIONE; 2 MERCAPTOBENZOTHIAZOLE; 2,2',4,4' TETRAHYDROXY BENZOPHENONE; 3,5 DIMETHYLPYRAZOLE 1 METHANOL; 4 NONYLPHENOL; 4 PROPOXYPHENOL; BENZOPHENONE DERIVATIVE; DAIDZEIN; DIETHYLHEXYLPHTHALATE; GENISTEIN; GUAIACOL; IOPANOIC ACID; PHENOL DERIVATIVE; PHTHALIC ACID DIBUTYL ESTER; PHTHALIC ACID DIETHYL ESTER; PROPYLTHIOURACIL; SODIUM PERCHLORATE; SULFADIMIDINE; THIAMAZOLE; THYROID HORMONE; THYROID PEROXIDASE; TRICLOSAN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CATALYST; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INHIBITION; HIGH THROUGHPUT SCREENING; MALE; MICROSOME; NONHUMAN; OXIDATION; RAT; THYROID HORMONE SYNTHESIS;

ANIMALS; ENZYME ASSAYS; ENZYME INHIBITORS; GUAIACOL; HIGH-THROUGHPUT SCREENING ASSAYS; MALE; METHIMAZOLE; MICROSOMES; OXAZINES; OXIDATION-REDUCTION; PEROXIDASE; PROTEIN BINDING; RATS; RATS, LONG-EVANS; SUBSTRATE SPECIFICITY; THYROID GLAND;

EID: 84896353700     PISSN: 0893228X     EISSN: 15205010     Source Type: Journal    
DOI: 10.1021/tx400310w     Document Type: Article

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