Active site structure and catalytic mechanisms of human peroxidases

Archives of Biochemistry and Biophysics

Volumn 445, Issue 2, 2006, Pages 199-213

  Furtmüller, Paul G ^a   Zederbauer, Martina ^a   Jantschko, Walter ^a   Helm, Jutta ^a   Bogner, Martin ^a   Jakopitsch, Christa ^a   Obinger, Christian ^a  

^a Department of Chemistry   (Austria)

Author keywords

Compound I; Compound II; Compound III; Eosinophil peroxidase; Halogenation activity; Lactoperoxidase; Myeloperoxidase; Peroxidase activity; Thyroid peroxidase; X ray structure

Indexed keywords

EOSINOPHIL PEROXIDASE; FERRIC PEROXIDASE; FERROUS PEROXIDASE; HEME; LACTOPEROXIDASE; MYELOPEROXIDASE; PEROXIDASE; THYROID PEROXIDASE; UNCLASSIFIED DRUG;

CATALYSIS; CRYSTAL STRUCTURE; HALOGENATION; HORMONE SYNTHESIS; HOST RESISTANCE; HUMAN; KINETICS; MAMMAL; OXIDATION REDUCTION REACTION; PATHOGENESIS; PRIORITY JOURNAL; REVIEW; SEQUENCE ANALYSIS; STRUCTURE ACTIVITY RELATION;

AMINO ACID SEQUENCE; BINDING SITES; CATALYSIS; ENZYME ACTIVATION; HUMANS; MOLECULAR SEQUENCE DATA; PEROXIDASES; PROTEIN CONFORMATION; STRUCTURE-ACTIVITY RELATIONSHIP; SUBSTRATE SPECIFICITY;

MAMMALIA;

EID: 30544454226     PISSN: 00039861     EISSN: 10960384     Source Type: Journal    
DOI: 10.1016/j.abb.2005.09.017     Document Type: Review

References (134)

1. K.G. Welinder Curr. Opin. Struct. Biol. 2 1992 388 393
2. K.G. Welinder, J.M. Mauro, and L. Norskov-Lauritsen Biochem. Soc. Trans. 20 1992 337 340
3. K.G. Welinder, and M. Gajhede K.G. Welinder S.K. Rasmussen C. Penel H. Greppin Plant Peroxidases: Biochemistry and Physiology 1993 University of Geneva 35 42
4. B.C. Finzel, T.L. Poulos, and J. Kraut J. Biol. Chem. 259 1984 13027 13036
5. T.L. Poulos, S.L. Edwards, H. Wariishi, and M.H. Gold J. Biol. Chem. 268 1993 4429 4440
6. M. Sundaramoorthy, K. Kishi, M.H. Gold, and T.L. Poulos Nat. Struct. Biol. 4 1994 1032 1038
7. W.R. Patterson, and T.L. Poulos Biochemistry 34 1995 4331 4341
8. D.J. Schuller, N. Ban, R.B. van Huystee, A. McPherson, and T.L. Poulos Structure 4 1996 311 321
9. M. Gajhede, D.J. Schuller, A. Henriksen, A.T. Smith, and T.L. Poulos Nat. Struct. Biol. 4 1997 1032 1038
10. S. Kimura, and M. Ikeda-Saito Proteins Struct. Funct. Genet. 3 1988 113 120
11. A. Taurog Biochimie 81 1999 557 562
12. H. Daivasu, and H. Toh J. Mol. Evol. 31 2000 433 445
13. T. Ueda, S. Sakamaki, and S. Nagata Eur. J. Biochem. 243 1997 32 41
14. W.M. Nauseef, S. McCormick, and M. Goedken Redox Rep. 5 2000 197 206
15. J. Zeng, and R.E. Fenna J. Mol. Biol. 226 1992 185 207
16. T.J. Fiedler, and C.A. Davey R.E. Fenna.J. Biol. Chem. 275 2000 11964 11971
17. R.E. Fenna A. Messerschmidt R. Huber T. Poulos K. Wieghardt Handbook of Metalloproteins 2001 John Wiley 211 221
18. K.S. Booth, S. Kimura, H.C. Lee, M. Ikeda-Saito, and W.W. Caughey Biochem. Biophys. Res. Commun. 60 1989 897 902
19. L. De Gioia, E.M. Ghibaudi, E. Laurenti, M. Salmona, and R.P. Ferrari J. Biol. Inorg. Chem. 1 1996 476 485
20. I. Olsson, A.M. Persson, K. Strömberg, I. Winqvist, P.C. Tai, and C.J.F. Spry Blood 66 1985 1143 1148
21. M.G. Carlson, C.G. Peterson, and P. Venge J. Immunol. 134 1985 1875 1879
22. T. Ueda, K. Sakamaki, T. Kuroki, I. Yano, and S. Nagata Eur. J. Biochem. 243 1997 32 41
23. G. Sievers FEBS Lett. 127 1981 253 256
24. B. Langbakk, and T. Flatmark Biochem. J. 259 1989 627 631
25. S. Kimura, T. Kotani, O.W. McBride, K. Umeki, K. Hirai, T. Nakayama, and S. Ohtaki Proc. Natl. Acad. Sci. USA 84 1987 5555 5559
26. J.R. Baker, P. Arscott, and L. Johnson Thyroid 4 1994 173 178
27. T. Nishikawa, B. Rapoport, and S.M. McLachlan J. Clin. Endocrinol. Metab. 79 1994 1648 1654
28. S.M. Wolf, R.P. Ferrari, S. Traversa, and K. Biemann J. Mass. Spectrom. 35 2000 210 217
29. A.R. Thomsen, L. Sottrup-Jensen, G.J. Gleich, and C. Oxvig Arch. Bioch. Biophys. 379 2000 147 152
30. C. Oxvig, A.R. Thomsen, M.T. Overgaard, E.S. Sorensen, P. Hojrup, M.J. Bjerrum, G.J. Gleich, and L. Sottrup-Jensen J. Biol. Chem. 274 1999 16953 16958
31. L.A. Andersson, S.A. Bylkas, and A.E. Wilson J. Biol. Chem. 271 1996 3406 3412
32. T.D. Rae, and H.M. Goff J. Am. Chem. Soc. 118 1996 2103 2104
33. G.D. DePillis, S. Ozaki, J.M. Kuo, D.A. Maltby, and P.R. Ortiz de Montellano J. Biol. Chem. 272 1997 8857 8860
34. G. Suriano, S. Watanabe, E.M. Ghibaudi, A. Bollen, R.P. Ferrari, and N. Moguilevsky Biorg. Med. Chem. Lett. 11 2001 2827 2831
35. C. Colas, J.M. Kuo, and P.R. Ortiz de Montellano J. Biol. Chem. 277 2002 7191 7200
36. L. Fayadat, P. Niccoli-Sire, J. Lanet, and J.-L. Franc J. Biol. Chem. 274 1999 10533 10538
37. P.C. Andrews, and N.I. Krinsky J. Biol. Chem. 256 1981 4211 4218
38. R. Wever, and H. Plat Biochim. Biophys. Acta 661 1981 235 239
39. I.M. Kooter, N. Moguilevsky, A. Bollen, N.M. Sijtsema, C. Otto, and R. Wever J. Biol. Inorg. Chem. 2 1997 191 197
40. I.M. Kooter, B.P. Koehler, N. Moguilevsky, A. Bollen, R. Wever, and M.K. Johnson J. Biol. Inorg. Chem. 4 1999 684 691
41. I.M. Kooter, N. Moguilevsky, A. Bollen, L.A. van der Veen, C. Otto, H.L. Dekker, and R. Wever J. Biol. Chem. 274 1999 26794 26802
42. S. Brogioni, A. Feis, M.P. Marzocchi, M. Zederbauer, P.G. Furtmüller, C. Obinger, G. Smulevich, J. Raman Spec. 36 (2005) in press.
43. B.G.J.M. Bolscher, H. Plat, and R. Wever Biochim. Biophys. Acta 784 1984 177 186
44. A. Carlstrom Acta Chem. Scand. 23 1969 203 213
45. H. Kohler, A. Taurog, and H.B. Dunford Arch. Biochem. Biophys. 264 1988 438 449
46. S. Watanabe, S. Murata, H. Kumura, S. Nakamura, A. Bollen, N. Moguilevsky, and K. Shimazaki Biochem. Biophys. Res. Commun. 274 2000 756 761
47. R.P. Ferrari, E. Laurenti, P.I. Gambino, and I. Sondergaard J. Inorg. Biochem. 58 1995 109 127
48. H.B. Dunford Heme Peroxidases 1999 Wiley-VCH New York
49. P.I. Ohlsson, and G. Paul Acta Chem. Scand. 37 1983 917 921
50. J.E. Harrison, and J. Schulz Biochim. Biophys. Acta 536 1978 341 346
51. M. Ikeda-Saito, and R.C. Prince J. Biol. Chem. 260 1985 8301 8305
52. B.G.J.M. Bolscher, and R. Wever Biochem. Biophys. Acta 788 1984 1 10
53. M. Ikeda-Saito Biochemistry 26 1987 4344 4349
54. D.G. Eglington, D. Barber, A.J. Thomson, C. Greenwood, and A.W. Segal Biochim. Biophys. Acta 703 1982 187 195
55. J.J. Lopez-Garriga, W.A. Oertling, R.T. Kean, H. Hoogland, R. Wever, and G.T. Babcock Biochemistry 29 1990 9387 9395
56. M. Blair-Johnson, T. Fiedler, and R. Fenna Biochemistry 40 2001 13990 13997
57. C.E. Cooper, and E. Odell FEBS Lett. 314 1992 58 60
58. U. Burner, P.G. Furtmüller, A.J. Kettle, W.H. Koppenol, and C. Obinger J. Biol. Chem. 275 2000 20597 20601
59. M. Ikeda-Saito J. Biol. Chem. 260 1985 11688 11696
60. M. Ikeda-Saito, P.V. Argade, and D.L. Rousseau FEBS Lett. 184 1985 52 55
61. A.R.J. Bakkenist, J.E.G. De Boer, H. Plat, and R. Wever Biochem. Biophys. Acta 613 1980 337 348
62. J.M. Zgliczynski, R.J. Selvaraj, B.B. Paul, T. Stelmaszynska, P.K.F. Poskitt, and A.J. Sbarra Proc. Exp. Biol. Med. 154 1977 418 422
63. I.M. Kooter, N. Moguilevsky, A. Bollen, N.M. Sijtsema, C. Otto, H.L. Dekker, and R. Wever Eur. J. Biochem. 264 1999 211 217
64. D. Dolman, H.B. Dunford, D.M. Chowhury, and M. Morrison Biochemistry 7 1968 3991 3996
65. G. Sievers Biochem. Biophys. Acta 624 1980 249 259
66. S. Hu, R.W. Treat, and J.R. Kincaid Biochemistry 32 1993 10125 10130
67. R.P. Ferrari, E.M. Ghibaudi, S. Traversa, E. Laurenti, L. De Gioia, and M. Salmona J. Inorg. Biochem. 68 1997 17 26
68. E. Ghibaudi, E. Laurenti, C. Pacchiardo, G. Suriano, N. Moguilevsky, and R.P. Ferrari J. Inorg. Biochem. 94 2003 146 154
69. H.M. Abu-Soud, and S.L. Hazen Biochemistry 40 2001 10747 10755
70. T.L. Poulos, and J. Kraut J. Biol. Chem. 255 1980 8199 8205
71. J.N. Rodriguez-Lopez, D.J. Lowe, J. Hernandez-Ruiz, A.N.P. Hiner, F. Garcia-Canovas, and R.N.F. Thorneley J. Am. Chem. Soc. 123 2001 11838 11847
72. G. Hamilton O. Hayaishi Chemical Models and Mechanism for Oxygenases 1974 Academic Press New York 405 451
73. D. Dolphin, A. Forman, D.C. Borg, J. Fajer, and R.H. Felton Proc. Natl. Acad. Sci. USA 68 1991 614 618
74. T. Odajima, and I. Yamazaki Biochim. Biophys. Acta 206 1979 71 77
75. J.E. Harrison, T. Araiso, M. Palcic, and H.B. Dunford Biochem. Biophys. Res. Commun. 94 1980 34 40
76. L.A. Marquez, J.T. Huang, and H.B. Dunford Biochemistry 33 1994 1447 1454
77. P.G. Furtmüller, U. Burner, and C. Obinger Biochemistry 37 1998 17923 17930
78. P.G. Furtmüller, U. Burner, G. Regelsberger, and C. Obinger Biochemistry 39 2000 15578 15584
79. P.G. Furtmüller, W. Jantschko, G. Regelsberger, C. Jakopitsch, J. Arnhold, and C. Obinger Biochemistry 41 2002 11895 11900
80. J.K. Hurst J. Everse K.E. Everse M.B. Grisham Peroxidases in Chemistry and Biology 1991 CRC Press Boca Raton 37 62
81. J. Arnhold, P.G. Furtmüller, G. Regelsberger, and C. Obinger Eur. J. Biochem. 268 2001 5142 5148
82. J. Arnhold, P.G. Furtmüller, and C. Obinger Redox Rep. 8 2003 179 186
83. W.H. Koppenol Bioelectrochem. Bioenerg. 18 1987 3 11
84. H. Iwamoto, T. Kobayashi, E. Hasegawa, and Y. Morita J. Biochem. 101 1987 1407 1412
85. A.J. Kettle, and C.C. Winterbourn Biochemistry 40 2001 10204 10212
86. D.T. Sawyer A.E. Martell D.T. Sawyer Oxygen Complexes and Oxygen Activation by Transistion metals 1988 Plenum Press New York 131
87. P.G. Furtmüller, U. Burner, W. Jantschko, G. Regelsberger, and C. Obinger FEBS Lett. 484 2000 139 143
88. P.G. Furtmüller, U. Burner, W. Jantschko, G. Regelsberger, and C. Obinger Redox Rep. 5 2000 173 178
89. M. Huwiler, and H. Kohler Eur. J. Biochem. 141 1984 69 74
90. M. Huwiler, H. Jenzer, and H. Kohler Eur. J. Biochem. 158 1986 609 614
91. W. Jantschko, P.G. Furtmüller, M. Zederbauer, M. Lanz, and C. Obinger Biochem. Biophys. Res. Commun. 312 2003 292 298
92. W. Jantschko, P.G. Furtmüller, M. Zederbauer, C. Jakopitsch, and C. Obinger Arch. Biochem. Biophys. 434 2004 91 97
93. W. Jantschko, P.G. Furtmüller, M. Zederbauer, K. Neugschwandtner, C. Jakopitsch, and C. Obinger Arch. Biochem. Biophys. 434 2005 51 59
94. B.G.J.N. Bolscher, and R. Wever Biochim. Biophys. Acta 788 1984 1 10
95. E. Ghibaudi, and E. Laurenti Eur. J. Biochem. 270 2003 4403 4412
96. P.G. Furtmüller, J. Arnhold, W. Jantschko, H. Pichler, and C. Obinger Biochem. Biophys. Res. Commun. 301 2003 551 557
97. P.G. Furtmüller, J. Arnhold, W. Jantschko, M. Zederbauer, C. Jakopitsch, and C. Obinger J. Inorg. Biochem. 99 2005 1220 1229
98. O.M. Lardinois, and P. Ortiz de Montellano Biochem. Biophys. Res. Commun. 270 2000 199 202
99. O.M. Lardinois, K.F. Medzihradsky, and P.R. Ortiz de Montellano J. Biol. Chem. 274 1999 35441 35448
100. H.M. Goff, and K. Chen J. Inorg. Biochem. 74 1999 143
101. E. Monzani, A.L. Gatti, A. Profumo, L. Casella, and M. Gullotti Biochemistry 36 1997 1918 1926
102. A. Taurog, M.L. Dorris, and D.R. Doerge Arch. Biochem. Biophys. 330 1996 24 32
103. F. Courtin, J.L. Michot, A. Virion, J. Pommier, and D. Deme Biochem. Biophys. Res. Commun. 121 1984 463 470
104. N. Moguilevsky, L. Garcia-Quintana, A. Jacquet, C. Tournay, L. Fabry, L. Oierard, and A. Bollen Eur. J. Biochem. 197 1991 605 614
105. P.G. Furtmüller, W. Jantschko, G. Regelsberger, C. Jakopitsch, N. Moguilevsky, and C. Obinger FEBS Lett. 503 2001 147 150
106. S. Watanabe, F. Varsalona, Y. Yung-Choon, J.-P. Guillaume, A. Bollen, K. Shimazaki, and N. Moguilevsky FEBS Lett. 441 1998 476 479
107. M. Zederbauer, W. Jantschko, K. Neugschwandtner, C. Jakopitsch, N. Moguilevsky, C. Obinger, and P.G. Furtmüller Biochemistry 44 2005 6482 6491
108. H.B. Dunford Redox Rep. 5 2000 169 171
109. L.A. Marquez, and H.B. Dunford J. Biol. Chem. 268 1994 7950 7956
110. P.G. Furtmüller, C. Obinger, Y. Hsuanyu, and H.B. Dunford Eur. J. Biochem. 267 2000 5858 5864
111. M. Ikeda-Saito, C. Lee, K. Adachi, H.S. Eck, R.C. Prince, K.S. Booth, W.S. Caughey, and S. Kimura J. Biol. Chem. 264 1989 4550 4563
112. P.C. Andrews, and N.I. Krinsky J. Biol. Chem. 257 1982 13240 13245
113. H.C. Lee, K.S. Booth, W.S. Caughey, and M. Ikeda-Saito Biochim. Biophys. Acta 1076 1991 317 320
114. L.A. Marquez, and H.B. Dunford J. Biol. Chem. 270 1995 30434 30440
115. L.A. Marquez, H.B. Dunford, and H. Van Wart J. Biol. Chem. 265 1990 5666 5670
116. B.G.J.M. Bolscher, G.R. Zoutberg, R.A. Cuperus, and R. Wever Biochim. Biophys. Acta 784 1984 189 191
117. K.W.M. Zuurbier, A.R.J. Bakkenist, R. Wever, and A.O. Muijsers Biochim. Biophys. Acta 1037 1990 140 146
118. L.A. Marquez, and H.B. Dunford Arch. Biochem. Biophys. 305 1993 414 420
119. M. Allegra, P.G. Furtmüller, W. Jantschko, M. Zederbauer, L. Tesoriere, M.A. Livrea, and C. Obinger Biochem. Biophys. Res. Commun. 332 2005 837 844
120. W. Jantschko, P.G. Furtmüller, M. Allegra, M.A. Livrea, C. Jakopitsch, G. Regelsberger, and C. Obinger Arch. Biochem. Biophys. 398 2002 12 22
121. U. Burner, C. Obinger, M. Paumann, and P.G. Furtmüller J. Biol. Chem. 274 1999 9494 9502
122. W. Jantschko, P.G. Furtmüller, M. Zederbauer, K. Neugschwandtner, I. Lehner, C. Jakopitsch, J. Arnhold, and C. Obinger Biochem. Pharmacol. 69 2005 1149 1157
123. P.G. Furtmüller, W. Jantschko, G. Regelsberger, and C. Obinger Biochim. Biophys. Acta 1548 2001 121 128
124. C.C. Winterbourn, and A.J. Kettle Basic Life Sci. 49 1988 823 827
125. A.J. Kettle, and L.P. Candaeis Redox Rep. 5 2000 179 184
126. S. Modi, D.V. Behere, and S. Mitra Biochim. Biophys. Acta 996 1989 214 225
127. M. Ikeda-Saito, D.A. Shelly, L. Lu, K.S. Booth, W.S. Caughey, and D. Kimura J. Biol. Chem. 266 1991 3611 3616
128. H. Hori, R.E. Fenna, S. Kimura, and M. Ikeda-Saito J. Biol. Chem. 269 1994 8388 8392
129. C.A. Davey, and R.E. Fenna Biochemistry 35 1996 10967 10973
130. P. Nicholls, I. Fita, and P.C. Loewen Adv. Inorg. Chem. 51 2001 51 106
131. W. Jantschko, P.G. Furtmüller, M. Zederbauer, M. Lanz, C. Jakopitsch, and C. Obinger Biochem. Biophys. Res. Commun. 312 2003 292 298
132. C.C. Winterbourn, R.C. Garcia, and A.W. Segal Biochem. J. 228 1985 583 592
133. F. Rossi Biochem. Biophys. Acta 853 1986 65 89
134. A.J. Kettle, D.F. Sangster, J.M. Gebicki, and C.C. Winterbourn Biochim. Biophys. Acta 956 1988 58 62