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Volumn 3, Issue , 2014, Pages

The impact of drug resistance on Mycobacterium tuberculosis physiology: What can we learn from rifampicin?

Author keywords

Epistasis; Fitness cost; RNA polymerase; rpoB; TB

Indexed keywords

RIFAMPICIN; RNA POLYMERASE BETA SUBUNIT;

EID: 84896281808     PISSN: None     EISSN: 22221751     Source Type: Journal    
DOI: 10.1038/emi.2014.17     Document Type: Review
Times cited : (106)

References (151)
  • 1
    • 53049109052 scopus 로고    scopus 로고
    • Meeting the challenge of antibiotic resistance
    • Cars O, Hogberg LD, Murray M et al. Meeting the challenge of antibiotic resistance. BMJ 2008; 337: a1438.
    • (2008) BMJ , vol.337
    • Cars, O.1    Hogberg, L.D.2    Murray, M.3
  • 3
    • 84878560475 scopus 로고    scopus 로고
    • World Health Organization. Geneva: WHO, (accessed December 2013)
    • World Health Organization. Global tuberculosis report 2013. Geneva: WHO, 2013. Available at http://www.who.int/tb/publications/globalreport/en/index.html (accessed December 2013).
    • (2013) Global Tuberculosis Report 2013
  • 4
    • 84872577328 scopus 로고    scopus 로고
    • What is the cost of diagnosis and management of drug resistant tuberculosis in South Africa?
    • Pooran A, Pieterson E, DavidsM, Theron G, Dheda K. What is the cost of diagnosis and management of drug resistant tuberculosis in South Africa? PLoS ONE 2013; 8: e54587.
    • (2013) PLoS ONE , vol.8
    • Pooran, A.1    Pieterson, E.2    Davidsm Theron, G.3    Dheda, K.4
  • 5
    • 69549111337 scopus 로고    scopus 로고
    • Antibiotics for emerging pathogens
    • Fischbach MA, Walsh CT. Antibiotics for emerging pathogens. Science 2009; 325: 1089-1093.
    • (2009) Science , vol.325 , pp. 1089-1093
    • Fischbach, M.A.1    Walsh, C.T.2
  • 6
    • 77952542701 scopus 로고    scopus 로고
    • Multidrug-resistant and extensively drug-resistant tuberculosis: A threat to global control of tuberculosis
    • Gandhi NR, Nunn P, Dheda K et al. Multidrug-resistant and extensively drug-resistant tuberculosis: a threat to global control of tuberculosis. Lancet 2010; 375: 1830- 1843.
    • (2010) Lancet , vol.375 , pp. 1830-1843
    • Gandhi, N.R.1    Nunn, P.2    Dheda, K.3
  • 7
    • 79953316022 scopus 로고    scopus 로고
    • Spontaneous emergence of multiple drug resistance in tuberculosis before and during therapy
    • Colijn C, Cohen T, Ganesh A, Murray M. Spontaneous emergence of multiple drug resistance in tuberculosis before and during therapy. PLoS ONE 2011; 6: e18327.
    • (2011) PLoS ONE , vol.6
    • Colijn, C.1    Cohen, T.2    Ganesh, A.3    Murray, M.4
  • 8
    • 7044234498 scopus 로고    scopus 로고
    • Modeling the emergence of the 'hot zones': Tuberculosis and the amplification dynamics of drug resistance
    • DOI 10.1038/nm1102
    • Blower SM, Chou T. Modeling the emergence of the 'hot zones': tuberculosis and the amplification dynamics of drug resistance. Nat Med 2004; 10: 1111-1116. (Pubitemid 39424873)
    • (2004) Nature Medicine , vol.10 , Issue.10 , pp. 1111-1116
    • Blower, S.M.1    Chou, T.2
  • 9
    • 84875264261 scopus 로고    scopus 로고
    • The heterogeneous evolution of multidrugresistant Mycobacterium tuberculosis
    • Muller B, Borrell S, Rose G, Gagneux S. The heterogeneous evolution of multidrugresistant Mycobacterium tuberculosis. Trends Genet 2012; 29: 160-169.
    • (2012) Trends Genet , vol.29 , pp. 160-169
    • Muller, B.1    Borrell, S.2    Rose, G.3    Gagneux, S.4
  • 10
    • 84884992001 scopus 로고    scopus 로고
    • Genomic analysis identifies targets of convergent positive selection in drug resistant Mycobacterium tuberculosis
    • Farhat MR, Shapiro BJ, Kieser K et al. Genomic analysis identifies targets of convergent positive selection in drug resistant Mycobacterium tuberculosis. Nat Genet 2013; 45: 1183-1189.
    • (2013) Nat Genet , vol.45 , pp. 1183-1189
    • Farhat, M.R.1    Shapiro, B.J.2    Kieser, K.3
  • 11
    • 84885009252 scopus 로고    scopus 로고
    • Genome sequencing of 161 Mycobacterium tuberculosis isolates from China identifies genes and intergenic regions associated with drug resistance
    • Zhang H, Li D, Zhao L et al. Genome sequencing of 161 Mycobacterium tuberculosis isolates from China identifies genes and intergenic regions associated with drug resistance. Nat Genet 2013; 45: 1255-1260.
    • (2013) Nat Genet , vol.45 , pp. 1255-1260
    • Zhang, H.1    Li, D.2    Zhao, L.3
  • 13
    • 84859545563 scopus 로고    scopus 로고
    • Microevolution of extensively drugresistant tuberculosis in Russia
    • Casali N, Nikolayevskyy V, Balabanova Y et al. Microevolution of extensively drugresistant tuberculosis in Russia. Genome Res 2012; 22: 735-745.
    • (2012) Genome Res , vol.22 , pp. 735-745
    • Casali, N.1    Nikolayevskyy, V.2    Balabanova, Y.3
  • 14
    • 78649321465 scopus 로고    scopus 로고
    • The non-clonality of drug resistance in Beijinggenotype isolates of Mycobacterium tuberculosis from the Western Cape of South Africa
    • Ioerger TR, Feng Y, Chen X et al. The non-clonality of drug resistance in Beijinggenotype isolates of Mycobacterium tuberculosis from the Western Cape of South Africa. BMC Genomics 2010; 11: 670.
    • (2010) BMC Genomics , vol.11 , pp. 670
    • Ioerger, T.R.1    Feng, Y.2    Chen, X.3
  • 15
    • 84869066832 scopus 로고    scopus 로고
    • Dynamic population changes in Mycobacterium tuberculosis during acquisition and fixation of drug resistance in patients
    • Sun G, Luo T, Yang C et al. Dynamic population changes in Mycobacterium tuberculosis during acquisition and fixation of drug resistance in patients. J Infect Dis 2012; 206: 1724-1733.
    • (2012) J Infect Dis , vol.206 , pp. 1724-1733
    • Sun, G.1    Luo, T.2    Yang, C.3
  • 16
    • 77949569493 scopus 로고    scopus 로고
    • Antibiotic resistance and its cost: Is it possible to reverse resistance?
    • Andersson DI, Hughes D. Antibiotic resistance and its cost: is it possible to reverse resistance? Nat Rev Microbiol 2010; 8: 260-271.
    • (2010) Nat Rev Microbiol , vol.8 , pp. 260-271
    • Andersson, D.I.1    Hughes, D.2
  • 17
    • 39849097831 scopus 로고    scopus 로고
    • RNA polymerase: The vehicle of transcription
    • Borukhov S, Nudler E. RNA polymerase: the vehicle of transcription. Trends Microbiol 2008; 16: 126-134.
    • (2008) Trends Microbiol , vol.16 , pp. 126-134
    • Borukhov, S.1    Nudler, E.2
  • 19
    • 84884995578 scopus 로고    scopus 로고
    • Out-of-Africa migration and Neolithic co-expansion of tuberculosis with modern humans
    • Comas I, Coscolla M, Luo T et al. Out-of-Africa migration and Neolithic co-expansion of tuberculosis with modern humans. Nat Genet 2013; 45: 1176-1182.
    • (2013) Nat Genet , vol.45 , pp. 1176-1182
    • Comas, I.1    Coscolla, M.2    Luo, T.3
  • 20
    • 0033812380 scopus 로고    scopus 로고
    • Role of individual drugs in the chemotherapy of tuberculosis
    • Mitchison DA. Role of individual drugs in the chemotherapy of tuberculosis. Int J Tuberc Lung Dis 2000; 4: 796-806.
    • (2000) Int J Tuberc Lung Dis , vol.4 , pp. 796-806
    • Mitchison, D.A.1
  • 21
    • 74249103796 scopus 로고    scopus 로고
    • Rifampin combination therapy for nonmycobacterial infections
    • Forrest GN, Tamura K. Rifampin combination therapy for nonmycobacterial infections. Clin Microbiol Rev 2010; 23: 14-34.
    • (2010) Clin Microbiol Rev , vol.23 , pp. 14-34
    • Forrest, G.N.1    Tamura, K.2
  • 22
    • 0031057479 scopus 로고    scopus 로고
    • The population dynamics of antimicrobial chemotherapy
    • Lipsitch M, Levin BR. The population dynamics of antimicrobial chemotherapy. Antimicrob Agents Chemother 1997; 41: 363-373. (Pubitemid 27111032)
    • (1997) Antimicrobial Agents and Chemotherapy , vol.41 , Issue.2 , pp. 363-373
    • Lipsitch, M.1    Levin, B.R.2
  • 23
    • 27644588268 scopus 로고    scopus 로고
    • Differential antibiotic susceptibilities of starved Mycobacterium tuberculosis isolates
    • DOI 10.1128/AAC.49.11.4778-4780.2005
    • Xie Z, Siddiqi N, Rubin EJ. Differential antibiotic susceptibilities of starved Mycobacterium tuberculosis isolates. Antimicrob Agents Chemother 2005; 49: 4778-4780. (Pubitemid 41552617)
    • (2005) Antimicrobial Agents and Chemotherapy , vol.49 , Issue.11 , pp. 4778-4780
    • Xie, Z.1    Siddiqi, N.2    Rubin, E.J.3
  • 24
    • 84874064350 scopus 로고    scopus 로고
    • Activities of drug combinations against Mycobacterium tuberculosis grown in aerobic and hypoxic acidic conditions
    • Piccaro G, Giannoni F, Filippini P, Mustazzolu A, Fattorini L. Activities of drug combinations against Mycobacterium tuberculosis grown in aerobic and hypoxic acidic conditions. Antimicrob Agents Chemother 2013; 57: 1428-1433.
    • (2013) Antimicrob Agents Chemother , vol.57 , pp. 1428-1433
    • Piccaro, G.1    Giannoni, F.2    Filippini, P.3    Mustazzolu, A.4    Fattorini, L.5
  • 25
    • 77957375205 scopus 로고    scopus 로고
    • Simple model for testing drugs against nonreplicating Mycobacterium tuberculosis
    • Sala C, Dhar N, Hartkoorn RC et al. Simple model for testing drugs against nonreplicating Mycobacterium tuberculosis. Antimicrob Agents Chemother 2010; 54: 4150-4158.
    • (2010) Antimicrob Agents Chemother , vol.54 , pp. 4150-4158
    • Sala, C.1    Dhar, N.2    Hartkoorn, R.C.3
  • 27
    • 70449705831 scopus 로고    scopus 로고
    • The spectrum of latent tuberculosis: Rethinking the biology and intervention strategies
    • Barry CE, 3rd, BoshoffHI, Dartois V et al. The spectrum of latent tuberculosis: rethinking the biology and intervention strategies. Nat Rev Microbiol 2009; 7: 845-855.
    • (2009) Nat Rev Microbiol , vol.7 , pp. 845-855
    • Barry III, C.E.1    Boshoff, H.I.2    Dartois, V.3
  • 28
    • 84879092940 scopus 로고    scopus 로고
    • The normalcy of dormancy: Common themes in microbial quiescence
    • Rittershaus ES, Baek SH, Sassetti CM. The normalcy of dormancy: common themes in microbial quiescence. Cell Host Microbe 2013; 13: 643-651.
    • (2013) Cell Host Microbe , vol.13 , pp. 643-651
    • Rittershaus, E.S.1    Baek, S.H.2    Sassetti, C.M.3
  • 29
    • 66649124513 scopus 로고    scopus 로고
    • The global burden of tuberculosis-combating drug resistance in difficult times
    • Donald PR, van Helden PD. The global burden of tuberculosis-combating drug resistance in difficult times. N Engl J Med 2009; 360: 2393-2395.
    • (2009) N Engl J Med , vol.360 , pp. 2393-2395
    • Donald, P.R.1    Van Helden, P.D.2
  • 30
    • 0033578701 scopus 로고    scopus 로고
    • Crystal structure of Thermus aquaticus core RNA polymerase at 3.3 A resolution
    • Zhang G, Campbell EA, Minakhin L,Richter C, Severinov K, Darst SA. Crystal structure of Thermus aquaticus core RNA polymerase at 3.3 A resolution. Cell 1999; 98: 811-824.
    • (1999) Cell , vol.98 , pp. 811-824
    • Zhang, G.1    Campbell, E.A.2    Minakhin Lrichter, C.3    Severinov, K.4    Darst, S.A.5
  • 31
    • 0038013991 scopus 로고    scopus 로고
    • RNA polymerase holoenzyme: Structure, function and biological implications
    • DOI 10.1016/S1369-5274(03)00036-5
    • Borukhov S, Nudler E. RNA polymerase holoenzyme: structure, function and biological implications. Curr Opin Microbiol 2003; 6: 93-100. (Pubitemid 36628650)
    • (2003) Current Opinion in Microbiology , vol.6 , Issue.2 , pp. 93-100
    • Borukhov, S.1    Nudler, E.2
  • 32
    • 0032466234 scopus 로고    scopus 로고
    • Molecular genetic basis of antimicrobial agent resistance in Mycobacterium tuberculosis: 1998 update
    • DOI 10.1054/tuld.1998.0002
    • Ramaswamy S, Musser JM. Molecular genetic basis of antimicrobial agent resistance in Mycobacterium tuberculosis: 1998 update. Tuber Lung Dis 1998; 79: 3-29. (Pubitemid 29050434)
    • (1998) Tubercle and Lung Disease , vol.79 , Issue.1 , pp. 3-29
    • Ramaswamy, S.1    Musser, J.M.2
  • 33
    • 0023749808 scopus 로고
    • Mapping and sequencing of mutations in the Escherichia coli rpoB gene that lead to rifampicin resistance
    • Jin DJ, Gross CA. Mapping and sequencing of mutations in the Escherichia coli rpoB gene that lead to rifampicin resistance. J Mol Biol 1988; 202: 45-58.
    • (1988) J Mol Biol , vol.202 , pp. 45-58
    • Jin, D.J.1    Gross, C.A.2
  • 34
    • 0000652832 scopus 로고    scopus 로고
    • Genetics of drug resistance in Mycobacterium tuberculosis
    • Washington, DC: ASM Press
    • Zhang Y, Telenti A. Genetics of drug resistance in Mycobacterium tuberculosis. Molecular genetics of mycobacteria. Washington, DC: ASM Press, 2000.
    • (2000) Molecular Genetics of Mycobacteria
    • Zhang, Y.1    Telenti, A.2
  • 35
    • 0035171535 scopus 로고    scopus 로고
    • Frequency of rpoB mutations inside and outside the cluster I region in rifampin-resistant clinical Mycobacterium tuberculosis isolates
    • DOI 10.1128/JCM.39.1.107-110.2001
    • Heep M, Brandstatter B, Rieger U et al. Frequency of rpoB mutations inside and outside the cluster I region in rifampin-resistant clinical Mycobacterium tuberculosis isolates. J Clin Microbiol 2001; 39: 107-110. (Pubitemid 32059577)
    • (2001) Journal of Clinical Microbiology , vol.39 , Issue.1 , pp. 107-110
    • Heep, M.1    Brandstatter, B.2    Rieger, U.3    Lehn, N.4    Richter, E.5    Rusch-Gerdes, S.6    Niemann, S.7
  • 36
    • 0034128725 scopus 로고    scopus 로고
    • Mutations at four distinct regions of the rpoB gene can reduce the susceptibility of Helicobacter pylori to rifamycins
    • DOI 10.1128/AAC.44.6.1713-1715.2000
    • Heep M, Odenbreit S, Beck D et al. Mutations at four distinct regions of the rpoB gene can reduce the susceptibility of Helicobacter pylori to rifamycins. Antimicrob Agents Chemother 2000; 44: 1713-1715. (Pubitemid 30340823)
    • (2000) Antimicrobial Agents and Chemotherapy , vol.44 , Issue.6 , pp. 1713-1715
    • Heep, M.1    Odenbreit, S.2    Beck, D.3    Decker, J.4    Prohaska, E.5    Rieger, U.6    Lehn, N.7
  • 38
    • 0032539903 scopus 로고    scopus 로고
    • The rpoB mutants destabilizing initiation complexes at stringently controlled promoters behave like "stringent" RNA polymerases in Escherichia coli
    • Zhou YN, Jin DJ. The rpoB mutants destabilizing initiation complexes at stringently controlled promoters behave like "stringent" RNA polymerases in Escherichia coli. Proc Natl Acad Sci USA 1998; 95: 2908-2913. (Pubitemid 128617610)
    • (1998) Proceedings of the National Academy of Sciences of the United States of America , vol.95 , Issue.6 , pp. 2908-2913
    • Zhou, Y.N.1    Jin, D.J.2
  • 39
    • 66149185679 scopus 로고    scopus 로고
    • Antibacterial discovery in actinomycetes strains with mutations in RNA polymerase or ribosomal protein S12
    • Hosaka T, Ohnishi-Kameyama M, Muramatsu H et al. Antibacterial discovery in actinomycetes strains with mutations in RNA polymerase or ribosomal protein S12. Nat Biotechnol 2009; 27: 462-464.
    • (2009) Nat Biotechnol , vol.27 , pp. 462-464
    • Hosaka, T.1    Ohnishi-Kameyama, M.2    Muramatsu, H.3
  • 40
    • 0027285455 scopus 로고
    • Genetic evidence for the interaction between Cluster I and Cluster III rifampicin resistant mutations
    • DOI 10.1006/jmbi.1993.1251
    • Singer M, Jin DJ, Walter WA, Gross CA. Genetic evidence for the interaction between cluster I and cluster III rifampicin resistant mutations. J Mol Biol 1993; 231: 1-5. (Pubitemid 23186592)
    • (1993) Journal of Molecular Biology , vol.231 , Issue.1 , pp. 1-5
    • Singer, M.1    Jin, D.J.2    Walter, W.A.3    Gross, C.A.4
  • 41
    • 0024319151 scopus 로고
    • Characterization of the pleiotropic phenotypes of rifampin-resistant rpoB mutants of Escherichia coli
    • Jin DJ, Gross CA. Characterization of the pleiotropic phenotypes of rifampin-resistant rpoB mutants of Escherichia coli. J Bacteriol 1989; 171: 5229-5231. (Pubitemid 19209090)
    • (1989) Journal of Bacteriology , vol.171 , Issue.9 , pp. 5229-5231
    • Jin, D.J.1    Gross, C.A.2
  • 42
    • 0026329122 scopus 로고
    • m for purine nucleotides during transcription elongation
    • Jin DJ, Gross CA. RpoB8, a rifampicin-resistant termination-proficient RNA polymerase, has an increased Km for purine nucleotides during transcription elongation. J Biol Chem 1991; 266: 14478-14485. (Pubitemid 21907528)
    • (1991) Journal of Biological Chemistry , vol.266 , Issue.22 , pp. 14478-14485
    • Jin, D.J.1    Gross, C.A.2
  • 43
    • 0023721705 scopus 로고
    • Characterization of the termination phenotypes of rifampicin-resistant mutants
    • Jin DJ, Walter WA, Gross CA. Characterization of the termination phenotypes of rifampicin-resistant mutants. J Mol Biol 1988; 202: 245-253.
    • (1988) J Mol Biol , vol.202 , pp. 245-253
    • Jin, D.J.1    Walter, W.A.2    Gross, C.A.3
  • 44
    • 0025062984 scopus 로고
    • Amino acid changes in conserved regions of the betasubunit of Escherichia coli RNA polymerase alter transcription pausing and termination
    • Landick R, Stewart J, Lee DN. Amino acid changes in conserved regions of the betasubunit of Escherichia coli RNA polymerase alter transcription pausing and termination. Genes Dev 1990; 4: 1623-1636.
    • (1990) Genes Dev , vol.4 , pp. 1623-1636
    • Landick, R.1    Stewart, J.2    Lee, D.N.3
  • 45
    • 0019495739 scopus 로고
    • Rifampin resistance mutations that alter the efficiency of transcription termination at the tryptophan operon attenuator
    • Yanofsky C, Horn V. Rifampin resistance mutations that alter the efficiency of transcription termination at the tryptophan operon attenuator. J Bacteriol 1981; 145: 1334-1341. (Pubitemid 11097353)
    • (1981) Journal of Bacteriology , vol.145 , Issue.3 , pp. 1334-1341
    • Yanofsky, C.1    Horn, V.2
  • 46
    • 0034540939 scopus 로고    scopus 로고
    • Mutations in the β subunit of the Bacillus subtilis RNA polymerase that confer both rifampicin resistance and hypersensitivity to NusG
    • Ingham CJ, Furneaux PA. Mutations in the ss subunit of the Bacillus subtilis RNA polymerase that confer both rifampicin resistance and hypersensitivity to NusG. Microbiology 2000; 146: 3041-3049. (Pubitemid 32007660)
    • (2000) Microbiology , vol.146 , Issue.12 , pp. 3041-3049
    • Ingham, C.J.1    Furneaux, P.A.2
  • 47
    • 0037121936 scopus 로고    scopus 로고
    • Modulation of DNA repair by mutations flanking the DNA channel through RNA polymerase
    • DOI 10.1093/emboj/cdf654
    • Trautinger BW, Lloyd RG. Modulation of DNA repair by mutations flanking the DNA channel through RNA polymerase. EMBO J 2002; 21: 6944-6953. (Pubitemid 36014566)
    • (2002) EMBO Journal , vol.21 , Issue.24 , pp. 6944-6953
    • Trautinger, B.W.1    Lloyd, R.G.2
  • 48
    • 34548533427 scopus 로고    scopus 로고
    • Transcription coupled nucleotide excision repair in Escherichia coli can be affected by changing the arginine at position 529 of the β subunit of RNA polymerase
    • DOI 10.1016/j.dnarep.2007.04.002, PII S156878640700170X
    • Ganesan AK, Smith AJ, Savery NJ, Zamos P, Hanawalt PC. Transcription coupled nucleotide excision repair in Escherichia coli can be affected by changing the arginine at position 529 of the beta subunit of RNA polymerase. DNA Repair (Amst) 2007; 6: 1434-1440. (Pubitemid 47385395)
    • (2007) DNA Repair , vol.6 , Issue.10 , pp. 1434-1440
    • Ganesan, A.K.1    Smith, A.J.2    Savery, N.J.3    Zamos, P.4    Hanawalt, P.C.5
  • 49
    • 77954371207 scopus 로고    scopus 로고
    • RNA polymerase mutations that facilitate replication progression in the rep uvrD recF mutant lacking two accessory replicative helicases
    • Baharoglu Z, Lestini R, Duigou S, Michel B. RNA polymerase mutations that facilitate replication progression in the rep uvrD recF mutant lacking two accessory replicative helicases. Mol Microbiol 2010; 77: 324-336.
    • (2010) Mol Microbiol , vol.77 , pp. 324-336
    • Baharoglu, Z.1    Lestini, R.2    Duigou, S.3    Michel, B.4
  • 50
    • 0018673593 scopus 로고
    • New tool for studying interactions of components of ribonucleic acid polymerase: Rifampin-dependent mutants
    • Dabbs ER. New tool for studying interactions of components of ribonucleic acid polymerase: rifampin-dependent mutants. J Bacteriol 1979; 139: 1072-1074. (Pubitemid 10226589)
    • (1979) Journal of Bacteriology , vol.139 , Issue.3 , pp. 1072-1074
    • Dabbs, E.R.1
  • 51
    • 1842859064 scopus 로고    scopus 로고
    • Growth of rifampin-dependent Mycobacterium tuberculosis in conditions without rifampin
    • Chinese
    • Zhong M, Wang Y, Sun C, Yin H, Wang A, Lou L. [Growth of rifampin-dependent Mycobacterium tuberculosis in conditions without rifampin]. Zhonghua Jie He He Hu Xi Za Zhi 2002; 25: 588-590. Chinese.
    • (2002) Zhonghua Jie He He Hu Xi Za Zhi , vol.25 , pp. 588-590
    • Zhong, M.1    Wang, Y.2    Sun, C.3    Yin, H.4    Wang, A.5    Lou, L.6
  • 52
    • 76149136735 scopus 로고    scopus 로고
    • An interesting case of rifampicin-dependent/ -enhanced multidrug-resistant tuberculosis
    • Zhong M, Zhang X, Wang Y et al. An interesting case of rifampicin-dependent/ -enhanced multidrug-resistant tuberculosis. Int J Tuberc Lung Dis 2010; 14: 40-44.
    • (2010) Int J Tuberc Lung Dis , vol.14 , pp. 40-44
    • Zhong, M.1    Zhang, X.2    Wang, Y.3
  • 53
    • 0028942364 scopus 로고
    • Novel mutation in 16S rRNA associated with streptomycin dependence in Mycobacterium tuberculosis
    • Honore N, Marchal G, Cole ST. Novel mutation in 16S rRNA associated with streptomycin dependence in Mycobacterium tuberculosis. Antimicrob Agents Chemother 1995; 39: 769-770.
    • (1995) Antimicrob Agents Chemother , vol.39 , pp. 769-770
    • Honore, N.1    Marchal, G.2    Cole, S.T.3
  • 54
    • 3042736016 scopus 로고    scopus 로고
    • Multiple rpoB mutants of Mycobacterium tuberculosis second-order selection [7]
    • Mokrousov I. Multiple rpoB mutants of Mycobacterium tuberculosis and second-order selection. Emerg Infect Dis 2004; 10: 1337-1338. (Pubitemid 38890958)
    • (2004) Emerging Infectious Diseases , vol.10 , Issue.7 , pp. 1337-1338
    • Mokrousov, I.1
  • 55
    • 0027278557 scopus 로고
    • Instability and decay of the primary structure of DNA
    • DOI 10.1038/362709a0
    • Lindahl T. Instability and decay of the primary structure of DNA. Nature 1993; 362: 709-715. (Pubitemid 23125973)
    • (1993) Nature , vol.362 , Issue.6422 , pp. 709-715
    • Lindahl, T.1
  • 56
    • 78049233666 scopus 로고    scopus 로고
    • The role of DNA repair in M. Tuberculosis pathogenesis
    • Warner DF. The role of DNA repair in M. tuberculosis pathogenesis. Drug Discov Today 2010; 7: e5-e11.
    • (2010) Drug Discov Today , vol.7
    • Warner, D.F.1
  • 57
    • 67650164516 scopus 로고    scopus 로고
    • Mycobacterial survival strategies in the phagosome: Defence against host stresses
    • Ehrt S, Schnappinger D. Mycobacterial survival strategies in the phagosome: defence against host stresses. Cell Microbiol 2009; 11: 1170-1178.
    • (2009) Cell Microbiol , vol.11 , pp. 1170-1178
    • Ehrt, S.1    Schnappinger, D.2
  • 58
    • 18844436675 scopus 로고    scopus 로고
    • Analysis of rpoB and pncA mutations in the published literature: An insight into the role of oxidative stress in Mycobacterium tuberculosis evolution?
    • DOI 10.1093/jac/dki069
    • O'Sullivan DM, McHugh TD, Gillespie SH. Analysis of rpoB and pncA mutations in the published literature: an insight into the role of oxidative stress in Mycobacterium tuberculosis evolution? J Antimicrob Chemother 2005; 55: 674-679. (Pubitemid 40691845)
    • (2005) Journal of Antimicrobial Chemotherapy , vol.55 , Issue.5 , pp. 674-679
    • O'Sullivan, D.M.1    McHugh, T.D.2    Gillespie, S.H.3
  • 59
    • 84879682699 scopus 로고    scopus 로고
    • Mycobacterium tuberculosis mutation rate estimates from different lineages predict substantial differences in the emergence of drug-resistant tuberculosis
    • Ford CB, Shah RR, Maeda MK et al. Mycobacterium tuberculosis mutation rate estimates from different lineages predict substantial differences in the emergence of drug-resistant tuberculosis. Nat Genet 2013; 45: 784-790.
    • (2013) Nat Genet , vol.45 , pp. 784-790
    • Ford, C.B.1    Shah, R.R.2    Maeda, M.K.3
  • 60
    • 79952807087 scopus 로고    scopus 로고
    • Mutations outside the rifampicin resistancedetermining region associated with rifampicin resistance in Mycobacterium tuberculosis
    • Siu GK, Zhang Y, Lau TC et al. Mutations outside the rifampicin resistancedetermining region associated with rifampicin resistance in Mycobacterium tuberculosis. J Antimicrob Chemother 2011; 66: 730-733.
    • (2011) J Antimicrob Chemother , vol.66 , pp. 730-733
    • Siu, G.K.1    Zhang, Y.2    Lau, T.C.3
  • 61
    • 77049083451 scopus 로고    scopus 로고
    • Diagnosis of drug-resistant tuberculosis: Reliability and rapidity of detection
    • Van Deun A, Martin A, Palomino JC. Diagnosis of drug-resistant tuberculosis: reliability and rapidity of detection. Int J Tuberc Lung Dis 2010; 14: 131-140.
    • (2010) Int J Tuberc Lung Dis , vol.14 , pp. 131-140
    • Van Deun, A.1    Martin, A.2    Palomino, J.C.3
  • 62
    • 84874346133 scopus 로고    scopus 로고
    • Evolutionary rescue from extinction is contingent on a lower rate of environmental change
    • Lindsey HA, Gallie J, Taylor S, Kerr B. Evolutionary rescue from extinction is contingent on a lower rate of environmental change. Nature 2013; 494: 463-467.
    • (2013) Nature , vol.494 , pp. 463-467
    • Lindsey, H.A.1    Gallie, J.2    Taylor, S.3    Kerr, B.4
  • 63
    • 65749116995 scopus 로고    scopus 로고
    • Enhanced heterogeneity of rpoB in Mycobacterium tuberculosis found at low pH
    • Jenkins C, Bacon J, Allnutt J et al. Enhanced heterogeneity of rpoB in Mycobacterium tuberculosis found at low pH. J Antimicrob Chemother 2009; 63: 1118-1120.
    • (2009) J Antimicrob Chemother , vol.63 , pp. 1118-1120
    • Jenkins, C.1    Bacon, J.2    Allnutt, J.3
  • 64
    • 1642543134 scopus 로고    scopus 로고
    • Effect of rpoB Mutations Conferring Rifampin Resistance on Fitness of Mycobacterium tuberculosis
    • DOI 10.1128/AAC.48.4.1289-1294.2004
    • Mariam DH, Mengistu Y, Hoffner SE, AndersonDI. Effect of rpoB mutations conferring rifampin resistance on fitness of Mycobacterium tuberculosis. Antimicrob Agents Chemother 2004; 48: 1289-1294. (Pubitemid 38405483)
    • (2004) Antimicrobial Agents and Chemotherapy , vol.48 , Issue.4 , pp. 1289-1294
    • Mariam, D.H.1    Mengistu, Y.2    Hoffner, S.E.3    Andersson, D.I.4
  • 65
    • 33748693294 scopus 로고    scopus 로고
    • The biological cost of mutational antibiotic resistance: Any practical conclusions?
    • DOI 10.1016/j.mib.2006.07.002, PII S1369527406001214, Antimicrobials/Genomics
    • Andersson DI. The biological cost of mutational antibiotic resistance: any practical conclusions? Curr Opin Microbiol 2006; 9: 461-465. (Pubitemid 44397630)
    • (2006) Current Opinion in Microbiology , vol.9 , Issue.5 , pp. 461-465
    • Andersson, D.I.1
  • 66
    • 33745726538 scopus 로고    scopus 로고
    • Impact of bacterial genetics on the transmission of isoniazid-resistant Mycobacterium tuberculosis
    • Gagneux S, Burgos MV, DeRiemer K et al. Impact of bacterial genetics on the transmission of isoniazid-resistant Mycobacterium tuberculosis. PLos Pathog 2006; 2: e61.
    • (2006) PLos Pathog , vol.2
    • Gagneux, S.1    Burgos, M.V.2    Deriemer, K.3
  • 67
    • 33745615117 scopus 로고    scopus 로고
    • The competitive cost of antibiotic resistance in Mycobacterium tuberculosis
    • DOI 10.1126/science.1124410
    • Gagneux S, Long CD, Small PM, Van T, Schoolnik GK, Bohannan BJ. The competitive cost of antibiotic resistance in Mycobacterium tuberculosis. Science 2006; 312: 1944-1946. (Pubitemid 43993719)
    • (2006) Science , vol.312 , Issue.5782 , pp. 1944-1946
    • Gagneux, S.1    Long, C.D.2    Small, P.M.3    Van, T.4    Schoolnik, G.K.5    Bohannan, B.J.M.6
  • 68
    • 7044285767 scopus 로고    scopus 로고
    • Modeling epidemics of multidrug-resistant M. Tuberculosis of heterogeneous fitness
    • DOI 10.1038/nm1110
    • Cohen T, Murray M. Modeling epidemics of multidrug-resistant M. tuberculosis of heterogenous fitness. Nat Med 2004; 10: 1117-1121. (Pubitemid 39424874)
    • (2004) Nature Medicine , vol.10 , Issue.10 , pp. 1117-1121
    • Cohen, T.1    Murray, M.2
  • 69
    • 73649107809 scopus 로고    scopus 로고
    • Infectiousness, reproductive fitness and evolution of drugresistant Mycobacterium tuberculosis
    • Borrell S, Gagneux S. Infectiousness, reproductive fitness and evolution of drugresistant Mycobacterium tuberculosis. Int J Tuberc Lung Dis 2009; 13: 1456-1466.
    • (2009) Int J Tuberc Lung Dis , vol.13 , pp. 1456-1466
    • Borrell, S.1    Gagneux, S.2
  • 70
    • 84886285421 scopus 로고    scopus 로고
    • Genetic characterization of compensatory evolution in strains carrying rpoB Ser531Leu, the rifampicin resistance mutation most frequently found in clinical isolates
    • Brandis G, Hughes D. Genetic characterization of compensatory evolution in strains carrying rpoB Ser531Leu, the rifampicin resistance mutation most frequently found in clinical isolates. J Antimicrob Chemother 2013; 68: 2493-2497.
    • (2013) J Antimicrob Chemother , vol.68 , pp. 2493-2497
    • Brandis, G.1    Hughes, D.2
  • 71
    • 0032876003 scopus 로고    scopus 로고
    • Physiological cost of rifampin resistance induced in vitro in Mycobacterium tuberculosis
    • Billington OJ, McHugh TD, Gillespie SH. Physiological cost of rifampin resistance induced in vitro in Mycobacterium tuberculosis. Antimicrob Agents Chemother 1999; 43: 1866-1869. (Pubitemid 29395177)
    • (1999) Antimicrobial Agents and Chemotherapy , vol.43 , Issue.8 , pp. 1866-1869
    • Billington, O.J.1    Mchugh, T.D.2    Gillespie, S.H.3
  • 72
    • 0033754403 scopus 로고    scopus 로고
    • Comparison of fitness of two isolates of Mycobacterium tuberculosis, one of which had developed multi-drug resistance during the course of treatment
    • Davies AP, Billington OJ, Bannister BA, Weir WR, McHugh TD, Gillespie SH. Comparison of fitness of two isolates of Mycobacterium tuberculosis, one of which had developed multi-drug resistance during the course of treatment. J Infect 2000; 41: 184-187.
    • (2000) J Infect , vol.41 , pp. 184-187
    • Davies, A.P.1    Billington, O.J.2    Bannister, B.A.3    Weir, W.R.4    McHugh, T.D.5    Gillespie, S.H.6
  • 73
    • 0036921959 scopus 로고    scopus 로고
    • Multiple drug-resistant mycobacterium tuberculosis: Evidence for changing fitness following passage through human hosts
    • Gillespie SH, Billington OJ, Breathnach A, McHugh TD. Multiple drug-resistant Mycobacterium tuberculosis: evidence for changing fitness following passage through human hosts. Microb Drug Resist 2002; 8: 273-279. (Pubitemid 36043693)
    • (2002) Microbial Drug Resistance , vol.8 , Issue.4 , pp. 273-279
    • Gillespie, S.H.1    Billington, O.J.2    Breathnach, A.3    McHugh, T.D.4
  • 75
    • 50149112177 scopus 로고    scopus 로고
    • Accumulation of mutants in aging bacterial colonies is due to growth under selection, not stress-induced mutagenesis
    • Wrande M, Roth JR, Hughes D. Accumulation of mutants in "aging" bacterial colonies is due to growth under selection, not stress-induced mutagenesis. Proc Natl Acad Sci USA 2008; 105: 11863-11868.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 11863-11868
    • Wrande, M.1    Roth, J.R.2    Hughes, D.3
  • 77
    • 84882470985 scopus 로고    scopus 로고
    • Early innate immunity determines outcome of Mycobacterium tuberculosis pulmonary infection in rabbits
    • Subbian S, Bandyopadhyay N, Tsenova L et al. Early innate immunity determines outcome of Mycobacterium tuberculosis pulmonary infection in rabbits. Cell Commun Signal 2013; 11: 60.
    • (2013) Cell Commun Signal , vol.11 , pp. 60
    • Subbian, S.1    Bandyopadhyay, N.2    Tsenova, L.3
  • 78
    • 84885003827 scopus 로고    scopus 로고
    • Evolution of high-level ethambutol-resistant tuberculosis through interacting mutations in decaprenylphosphoryl-b-D-arabinose biosynthetic and utilization pathway genes
    • Safi H, Lingaraju S, Amin A et al. Evolution of high-level ethambutol-resistant tuberculosis through interacting mutations in decaprenylphosphoryl-b-D-arabinose biosynthetic and utilization pathway genes. Nat Genet 2013; 45: 1190-1197.
    • (2013) Nat Genet , vol.45 , pp. 1190-1197
    • Safi, H.1    Lingaraju, S.2    Amin, A.3
  • 79
    • 84555209977 scopus 로고    scopus 로고
    • Whole-genome sequencing of rifampicin-resistant Mycobacterium tuberculosis strains identifies compensatory mutations in RNA polymerase genes
    • Comas I, Borrell S, Roetzer A et al. Whole-genome sequencing of rifampicin-resistant Mycobacterium tuberculosis strains identifies compensatory mutations in RNA polymerase genes. Nat Genet 2012; 44: 106-110.
    • (2012) Nat Genet , vol.44 , pp. 106-110
    • Comas, I.1    Borrell, S.2    Roetzer, A.3
  • 80
    • 84871683865 scopus 로고    scopus 로고
    • Mycobacterial lineages causing pulmonary and extrapulmonary tuberculosis, Ethiopia
    • Firdessa R, Berg S, Hailu E et al. Mycobacterial lineages causing pulmonary and extrapulmonary tuberculosis, Ethiopia. Emerg Infect Dis 2013; 19: 460-463.
    • (2013) Emerg Infect Dis , vol.19 , pp. 460-463
    • Firdessa, R.1    Berg, S.2    Hailu, E.3
  • 81
    • 84872834065 scopus 로고    scopus 로고
    • Putative compensatory mutations in the rpoC gene of rifampin-resistant Mycobacterium tuberculosis are associated with ongoing transmission
    • de Vos M, Muller B, Borrell S et al. Putative compensatory mutations in the rpoC gene of rifampin-resistant Mycobacterium tuberculosis are associated with ongoing transmission. Antimicrob Agents Chemother 2013; 57: 827-832.
    • (2013) Antimicrob Agents Chemother , vol.57 , pp. 827-832
    • De Vos, M.1    Muller, B.2    Borrell, S.3
  • 82
    • 84862767856 scopus 로고    scopus 로고
    • Fitness-compensatory mutations in rifampicin-resistant RNA polymerase
    • Brandis G, Wrande M, Liljas L, Hughes D. Fitness-compensatory mutations in rifampicin-resistant RNA polymerase. Mol Microbiol 2012; 85: 142-151.
    • (2012) Mol Microbiol , vol.85 , pp. 142-151
    • Brandis, G.1    Wrande, M.2    Liljas, L.3    Hughes, D.4
  • 83
    • 0036797562 scopus 로고    scopus 로고
    • Epistasis: What it means, what it doesn't mean, and statistical methods to detect it in humans
    • Cordell HJ. Epistasis: what it means, what it doesn't mean, and statistical methods to detect it in humans. Hum Mol Genet 2002; 11: 2463-2468. (Pubitemid 35174710)
    • (2002) Human Molecular Genetics , vol.11 , Issue.20 , pp. 2463-2468
    • Cordell, H.J.1
  • 85
    • 84890417237 scopus 로고    scopus 로고
    • Fitness benefits in fluoroquinolone-resistant Salmonella Typhi in the absence of antimicrobial pressure
    • Baker S, Duy PT, Nga TV et al. Fitness benefits in fluoroquinolone- resistant Salmonella Typhi in the absence of antimicrobial pressure. Elife 2013; 2: e01229.
    • (2013) Elife , vol.2
    • Baker, S.1    Duy, P.T.2    Nga, T.V.3
  • 86
    • 79953197586 scopus 로고    scopus 로고
    • The fitness cost of rifampicin resistance in Pseudomonas aeruginosa depends on demand for RNA polymerase
    • Hall AR, James IC, Maclean C. The fitness cost of rifampicin resistance in Pseudomonas aeruginosa depends on demand for RNA polymerase. Genetics 2011; 187: 817-822.
    • (2011) Genetics , vol.187 , pp. 817-822
    • Hall, A.R.1    James, I.C.2    Maclean, C.3
  • 87
    • 84855319056 scopus 로고    scopus 로고
    • Pre-existing isoniazid resistance, but not the genotype of Mycobacterium tuberculosis drives rifampicin resistance codon preference in vitro
    • Bergval I, Kwok B, Schuitema A et al. Pre-existing isoniazid resistance, but not the genotype of Mycobacterium tuberculosis drives rifampicin resistance codon preference in vitro. PLoS ONE 2012; 7: e29108.
    • (2012) PLoS ONE , vol.7
    • Bergval, I.1    Kwok, B.2    Schuitema, A.3
  • 89
    • 0033711560 scopus 로고    scopus 로고
    • Mutations at amino acid position 315 of the katG gene are associated with high-level resistance to isoniazid, other drug resistance, and successful transmission of Mycobacteriumtuberculosis in the Netherlands
    • van Soolingen D, de Haas PE, van Doorn HR, Kuijper E, Rinder H, Borgdorff MW. Mutations at amino acid position 315 of the katG gene are associated with high-level resistance to isoniazid, other drug resistance, and successful transmission of Mycobacteriumtuberculosis in the Netherlands. J Infect Dis 2000; 182: 1788-1790.
    • (2000) J Infect Dis , vol.182 , pp. 1788-1790
    • Van Soolingen, D.1    De Haas, P.E.2    Van Doorn, H.R.3    Kuijper, E.4    Rinder, H.5    Borgdorff, M.W.6
  • 90
    • 84892970335 scopus 로고    scopus 로고
    • Epistasis between antibiotic resistance mutations drives the evolution of extensively drug-resistant tuberculosis
    • Borrell S, Teo Y, Giardina F et al. Epistasis between antibiotic resistance mutations drives the evolution of extensively drug-resistant tuberculosis. EMPH 2013; 2013: 65-74.
    • (2013) EMPH , vol.2013 , pp. 65-74
    • Borrell, S.1    Teo, Y.2    Giardina, F.3
  • 91
    • 84866147787 scopus 로고    scopus 로고
    • Rates of gyrase supercoiling and transcription elongation control supercoil density in a bacterial chromosome
    • Rovinskiy N, Agbleke AA, Chesnokova O, Pang Z, Higgins NP. Rates of gyrase supercoiling and transcription elongation control supercoil density in a bacterial chromosome. PLoS Genet 2012; 8: e1002845.
    • (2012) PLoS Genet , vol.8
    • Rovinskiy, N.1    Agbleke, A.A.2    Chesnokova, O.3    Pang, Z.4    Higgins, N.P.5
  • 92
    • 33644531249 scopus 로고    scopus 로고
    • Variable host-pathogen compatibility in Mycobacterium tuberculosis
    • Gagneux S, DeRiemer K, Van T et al. Variable host-pathogen compatibility in Mycobacterium tuberculosis. Proc Natl Acad Sci USA 2006; 103: 2869-2873.
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 2869-2873
    • Gagneux, S.1    Van D. K, T.2
  • 93
    • 77955362067 scopus 로고    scopus 로고
    • Directed mutagenesis of Mycobacterium smegmatis 16S rRNA to reconstruct the in-vivo evolution of aminoglycoside resistance in Mycobacterium tuberculosis
    • Shcherbakov D, Akbergenov R, Matt T, Sander P, Andersson DI, Bottger EC. Directed mutagenesis of Mycobacterium smegmatis 16S rRNA to reconstruct the in-vivo evolution of aminoglycoside resistance in Mycobacterium tuberculosis. Mol Microbiol 2010; 77: 830-840.
    • (2010) Mol Microbiol , vol.77 , pp. 830-840
    • Shcherbakov, D.1    Akbergenov, R.2    Matt, T.3    Sander, P.4    Andersson, D.I.5    Bottger, E.C.6
  • 94
    • 79952188717 scopus 로고    scopus 로고
    • Deep resequencing of serial sputum isolates of Mycobacterium tuberculosis during therapeutic failure due to poor compliance reveals stepwise mutation of key resistance genes on an otherwise stable genetic background
    • Saunders NJ, Trivedi UH, Thomson ML, Doig C, Laurenson IF, Blaxter ML. Deep resequencing of serial sputum isolates of Mycobacterium tuberculosis during therapeutic failure due to poor compliance reveals stepwise mutation of key resistance genes on an otherwise stable genetic background. J Infect 2011; 62: 212-217.
    • (2011) J Infect , vol.62 , pp. 212-217
    • Saunders, N.J.1    Trivedi, U.H.2    Thomson, M.L.3    Doig, C.4    Laurenson, I.F.5    Blaxter, M.L.6
  • 97
    • 77950593250 scopus 로고    scopus 로고
    • A mutation in Mycobacterium tuberculosis rpoB gene confers rifampin resistance in three HIV-TB cases
    • Malhotra S, Cook VJ, Wolfe JN, Tang P, Elwood K, Sharma MK. A mutation in Mycobacterium tuberculosis rpoB gene confers rifampin resistance in three HIV-TB cases. Tuberculosis (Edinb) 2010; 90: 152-157.
    • (2010) Tuberculosis (Edinb) , vol.90 , pp. 152-157
    • Malhotra, S.1    Cook, V.J.2    Wolfe, J.N.3    Tang, P.4    Elwood, K.5    Sharma, M.K.6
  • 98
    • 77749267930 scopus 로고    scopus 로고
    • Mutations in extensively drug-resistant Mycobacterium tuberculosis that do not code for known drug-resistance mechanisms
    • Motiwala AS, Dai Y, Jones-Lopez EC et al. Mutations in extensively drug-resistant Mycobacterium tuberculosis that do not code for known drug-resistance mechanisms. J Infect Dis 2010; 201: 881-888.
    • (2010) J Infect Dis , vol.201 , pp. 881-888
    • Motiwala, A.S.1    Dai, Y.2    Jones-Lopez, E.C.3
  • 99
    • 73649138940 scopus 로고    scopus 로고
    • Molecular evolution of multisubunit RNA polymerases: Sequence analysis
    • Lane WJ, Darst SA. Molecular evolution of multisubunit RNA polymerases: sequence analysis. J Mol Biol 2010; 395: 671-685.
    • (2010) J Mol Biol , vol.395 , pp. 671-685
    • Lane, W.J.1    Darst, S.A.2
  • 100
    • 73649093377 scopus 로고    scopus 로고
    • Molecular evolution of multisubunit RNA polymerases: Structural analysis
    • Lane WJ, Darst SA. Molecular evolution of multisubunit RNA polymerases: structural analysis. J Mol Biol 2010; 395: 686-704.
    • (2010) J Mol Biol , vol.395 , pp. 686-704
    • Lane, W.J.1    Darst, S.A.2
  • 101
    • 0036717711 scopus 로고    scopus 로고
    • The spectrum of spontaneous rifampin resistance mutations in the rpoB gene of Bacillus subtilis 168 spores differs from that of vegetative cells and resembles that of Mycobacterium tuberculosis
    • Nicholson WL, Maughan H. The spectrum of spontaneous rifampin resistance mutations in the rpoB gene of Bacillus subtilis 168 spores differs from that of vegetative cells and resembles that of Mycobacterium tuberculosis. J Bacteriol 2002; 184: 4936-4940.
    • (2002) J Bacteriol , vol.184 , pp. 4936-4940
    • Nicholson, W.L.1    Maughan, H.2
  • 102
    • 1842506691 scopus 로고    scopus 로고
    • Novel rpoB Mutations Conferring Rifampin Resistance on Bacillus subtilis: Global Effects on Growth, Competence, Sporulation, and Germination
    • DOI 10.1128/JB.186.8.2481-2486.2004
    • Maughan H, Galeano B, Nicholson WL. Novel rpoB mutations conferring rifampin resistance on Bacillus subtilis: global effects on growth, competence, sporulation, and germination. J Bacteriol 2004; 186: 2481-2486. (Pubitemid 38451852)
    • (2004) Journal of Bacteriology , vol.186 , Issue.8 , pp. 2481-2486
    • Maughan, H.1    Galeano, B.2    Nicholson, W.L.3
  • 103
    • 38649112604 scopus 로고    scopus 로고
    • Uncovering new metabolic capabilities of Bacillus subtilis using phenotype profiling of rifampin-resistant rpoB mutants
    • DOI 10.1128/JB.00901-07
    • Perkins AE, Nicholson WL. Uncovering new metabolic capabilities of Bacillus subtilis using phenotype profiling of rifampin-resistant rpoB mutants. J Bacteriol 2008; 190: 807-814. (Pubitemid 351170923)
    • (2008) Journal of Bacteriology , vol.190 , Issue.3 , pp. 807-814
    • Perkins, A.E.1    Nicholson, W.L.2
  • 104
    • 0036460093 scopus 로고    scopus 로고
    • A rifampicin resistance mutation in the rpoB gene confers ppGpp-independent antibiotic production in Streptomyces coelicolor A3(2)
    • DOI 10.1007/s00438-002-0730-1
    • Xu J, Tozawa Y, Lai C, Hayashi H, Ochi K. A rifampicin resistance mutation in the rpoB gene confers ppGpp-independent antibiotic production in Streptomyces coelicolor A3(2). Mol Genet Genomics 2002; 268: 179-189. (Pubitemid 35471769)
    • (2002) Molecular Genetics and Genomics , vol.268 , Issue.2 , pp. 179-189
    • Xu, J.1    Tozawa, Y.2    Lai, C.3    Hayashi, H.4    Ochi, K.5
  • 105
    • 0036299643 scopus 로고    scopus 로고
    • Activation of antibiotic biosynthesis by specified mutations in the rpoB gene (encoding the RNA polymerase β subunit) of Streptomyces lividans
    • DOI 10.1128/JB.184.14.3984-3991.2002
    • Hu H, Zhang Q, Ochi K. Activation of antibiotic biosynthesis by specified mutations in the rpoB gene (encoding the RNA polymerase beta subunit) of Streptomyces lividans. J Bacteriol 2002; 184: 3984-3991. (Pubitemid 34705457)
    • (2002) Journal of Bacteriology , vol.184 , Issue.14 , pp. 3984-3991
    • Hu, H.1    Zhang, Q.2    Ochi, K.3
  • 106
    • 0942265514 scopus 로고    scopus 로고
    • RNA Polymerase Mutation Activates the Production of a Dormant Antibiotic 3,3′-Neotrehalosadiamine via an Autoinduction Mechanism in Bacillus subtilis
    • DOI 10.1074/jbc.M309925200
    • Inaoka T, Takahashi K, Yada H, Yoshida M, Ochi K. RNA polymerase mutation activates the production of a dormant antibiotic 3,39-neotrehalosadiamine via an autoinduction mechanism in Bacillus subtilis. J Biol Chem 2004; 279: 3885-3892. (Pubitemid 38140634)
    • (2004) Journal of Biological Chemistry , vol.279 , Issue.5 , pp. 3885-3892
    • Inaoka, T.1    Takahashi, K.2    Yada, H.3    Yoshida, M.4    Ochi, K.5
  • 107
    • 0347536251 scopus 로고    scopus 로고
    • Isolation of RNA Polymerase Suppressors of a (p)ppGpp Deficiency
    • DOI 10.1016/S0076-6879(03)71044-1
    • Murphy H, Cashel M. Isolation of RNA polymerase suppressors of a (p) ppGpp deficiency. Methods Enzymol 2003; 371: 596-601. (Pubitemid 37542760)
    • (2003) Methods in Enzymology , vol.371 , pp. 596-601
    • Murphy, H.1    Cashel, M.2
  • 108
    • 47249153619 scopus 로고    scopus 로고
    • Impact of individual mutations on increased fitness in adaptively evolved strains of Escherichia coli
    • DOI 10.1128/JB.01976-07
    • Applebee MK, Herrgard MJ, Palsson BO. Impact of individual mutations on increased fitness in adaptively evolved strains of Escherichia coli. J Bacteriol 2008; 190: 5087-5094. (Pubitemid 351991076)
    • (2008) Journal of Bacteriology , vol.190 , Issue.14 , pp. 5087-5094
    • Applebee, M.K.1    Herrgard, M.J.2    Palsson, B.O.3
  • 109
    • 78650546051 scopus 로고    scopus 로고
    • RNA polymerase mutants found through adaptive evolution reprogram Escherichia coli for optimal growth in minimal media
    • Conrad TM, Frazier M, Joyce AR et al. RNA polymerase mutants found through adaptive evolution reprogram Escherichia coli for optimal growth in minimal media. Proc Natl Acad Sci USA 2010; 107: 20500-20505.
    • (2010) Proc Natl Acad Sci USA , vol.107 , pp. 20500-20505
    • Conrad, T.M.1    Frazier, M.2    Joyce, A.R.3
  • 111
    • 84874100936 scopus 로고    scopus 로고
    • Evolution of Escherichia coli rifampicin resistance in an antibiotic-free environment during thermal stress
    • Rodriguez-Verdugo A, Gaut BS, Tenaillon O. Evolution of Escherichia coli rifampicin resistance in an antibiotic-free environment during thermal stress. BMC Evol Biol 2013; 13: 50.
    • (2013) BMC Evol Biol , vol.13 , pp. 50
    • Rodriguez-Verdugo, A.1    Gaut, B.S.2    Tenaillon, O.3
  • 112
    • 80051572614 scopus 로고    scopus 로고
    • Rifampicin reduces susceptibility to ofloxacin in rifampicin-resistant Mycobacterium tuberculosis through efflux
    • Louw GE, Warren RM, Gey van Pittius NC et al. Rifampicin reduces susceptibility to ofloxacin in rifampicin-resistant Mycobacterium tuberculosis through efflux. Am J Respir Crit Care Med 2011; 184: 269-276.
    • (2011) Am J Respir Crit Care Med , vol.184 , pp. 269-276
    • Louw, G.E.1    Warren, R.M.2    Gey Van Pittius, N.C.3
  • 113
    • 84871057692 scopus 로고    scopus 로고
    • Upregulation of the phthiocerol dimycocerosate biosynthetic pathway by rifampin-resistant, rpoB mutant Mycobacterium tuberculosis
    • Bisson GP, Mehaffy C, Broeckling C et al. Upregulation of the phthiocerol dimycocerosate biosynthetic pathway by rifampin-resistant, rpoB mutant Mycobacterium tuberculosis. J Bacteriol 2012; 194: 6441-6452.
    • (2012) J Bacteriol , vol.194 , pp. 6441-6452
    • Bisson, G.P.1    Mehaffy, C.2    Broeckling, C.3
  • 114
    • 84868343034 scopus 로고    scopus 로고
    • Altered fatty acid metabolism due to rifampicin-resistance conferring mutations in the rpoB gene of Mycobacterium tuberculosis: Mapping the potential of pharmaco-metabolomics for global health and personalized medicine
    • du Preez I, Loots D. Altered fatty acid metabolism due to rifampicin-resistance conferring mutations in the rpoB gene of Mycobacterium tuberculosis: mapping the potential of pharmaco-metabolomics for global health and personalized medicine. Omics, 2012, 16 596-603.
    • (2012) Omics , vol.16 , pp. 596-603
    • Du Preez, I.1    Loots, D.2
  • 115
    • 34548758472 scopus 로고    scopus 로고
    • Specific mutations in the Mycobacterium tuberculosis rpoB gene are associated with increased dnaE2 expression
    • DOI 10.1111/j.1574-6968.2007.00905.x
    • Bergval IL, Klatser PR, Schuitema AR, Oskam L, Anthony RM. Specific mutations in the Mycobacterium tuberculosis rpoB gene are associated with increased dnaE2 expression. FEMS Microbiol Lett 2007; 275: 338-343. (Pubitemid 47437870)
    • (2007) FEMS Microbiology Letters , vol.275 , Issue.2 , pp. 338-343
    • Bergval, I.L.1    Klatser, P.R.2    Schuitema, A.R.J.3    Oskam, L.4    Anthony, R.M.5
  • 116
    • 0030051153 scopus 로고    scopus 로고
    • Rifampin resistance in Neisseria meningitidis due to alterations in membrane permeability
    • Abadi FJ, Carter PE, Cash P, Pennington TH. Rifampin resistance in Neisseria meningitidis due to alterations in membrane permeability. Antimicrob Agents Chemother 1996; 40: 646-651. (Pubitemid 26071531)
    • (1996) Antimicrobial Agents and Chemotherapy , vol.40 , Issue.3 , pp. 646-651
    • Abadi, F.J.R.1    Carter, P.E.2    Cash, P.3    Pennington, T.H.4
  • 117
    • 63449126395 scopus 로고    scopus 로고
    • Activation of dormant bacterial genes by Nonomuraea sp. Strain ATCC 39727 mutant-type RNA polymerase
    • Tala A, Wang G, Zemanova M, Okamoto S, Ochi K, Alifano P. Activation of dormant bacterial genes by Nonomuraea sp. strain ATCC 39727 mutant-type RNA polymerase. J Bacteriol 2009; 191: 805-814.
    • (2009) J Bacteriol , vol.191 , pp. 805-814
    • Tala, A.1    Wang, G.2    Zemanova, M.3    Okamoto, S.4    Ochi, K.5    Alifano, P.6
  • 119
    • 33645767209 scopus 로고    scopus 로고
    • Contribution of rpoB2 RNA polymerase beta subunit gene to rifampin resistance in Nocardia species
    • Ishikawa J, Chiba K, Kurita H, Satoh H. Contribution of rpoB2 RNA polymerase beta subunit gene to rifampin resistance in Nocardia species. Antimicrob Agents Chemother 2006; 50: 1342-1346.
    • (2006) Antimicrob Agents Chemother , vol.50 , pp. 1342-1346
    • Ishikawa, J.1    Chiba, K.2    Kurita, H.3    Satoh, H.4
  • 120
    • 17444370967 scopus 로고    scopus 로고
    • Monitoring in vivo fitness of rifampicin-resistant Staphylococcus aureus mutants in a mouse biofilm infection model
    • DOI 10.1093/jac/dki053
    • Yu J, Wu J, Francis KP, Purchio TF, Kadurugamuwa JL. Monitoring in vivo fitness of rifampicin-resistant Staphylococcus aureus mutants in a mouse biofilm infection model. J Antimicrob Chemother 2005; 55: 528-534. (Pubitemid 40542595)
    • (2005) Journal of Antimicrobial Chemotherapy , vol.55 , Issue.4 , pp. 528-534
    • Yu, J.1    Wu, J.2    Francis, K.P.3    Purchio, T.F.4    Kadurugamuwa, J.L.5
  • 121
    • 78649669062 scopus 로고    scopus 로고
    • An RpoB mutation confers dual heteroresistance to daptomycin and vancomycin in Staphylococcus aureus
    • Cui L, Isii T, Fukuda M et al. An RpoB mutation confers dual heteroresistance to daptomycin and vancomycin in Staphylococcus aureus. Antimicrob Agents Chemother 2010; 54: 5222-5233.
    • (2010) Antimicrob Agents Chemother , vol.54 , pp. 5222-5233
    • Cui, L.1    Isii, T.2    Fukuda, M.3
  • 122
    • 79959846590 scopus 로고    scopus 로고
    • Impact of rpoB mutations on reduced vancomycin susceptibility in Staphylococcus aureus
    • Watanabe Y, Cui L, Katayama Y, Kozue K, Hiramatsu K. Impact of rpoB mutations on reduced vancomycin susceptibility in Staphylococcus aureus. J Clin Microbiol 2011; 49: 2680-2684.
    • (2011) J Clin Microbiol , vol.49 , pp. 2680-2684
    • Watanabe, Y.1    Cui, L.2    Katayama, Y.3    Kozue, K.4    Hiramatsu, K.5
  • 123
    • 0023626550 scopus 로고
    • Metabolic initiation of differentiation and secondary metabolism by Streptomyces griseus: Significance of the stringent response (ppGpp) and GTP content in relation to a factor
    • Ochi K. Metabolic initiation of differentiation and secondary metabolism by Streptomyces griseus: significance of the stringent response (ppGpp) and GTP content in relation to A factor. J Bacteriol 1987; 169: 3608-3616. (Pubitemid 17160317)
    • (1987) Journal of Bacteriology , vol.169 , Issue.8 , pp. 3608-3616
    • Ochi, K.1
  • 126
    • 0033872759 scopus 로고    scopus 로고
    • The stringent response of Mycobacterium tuberculosis is required for long-term survival
    • DOI 10.1128/JB.182.17.4889-4898.2000
    • Primm TP, Andersen SJ, Mizrahi V, Avarbock D, Rubin H, BarryCE 3rd. The stringent response of Mycobacterium tuberculosis is required for long-term survival. J Bacteriol 2000; 182: 4889-4898. (Pubitemid 30641814)
    • (2000) Journal of Bacteriology , vol.182 , Issue.17 , pp. 4889-4898
    • Primm, T.P.1    Andersen, S.J.2    Mizrahi, V.3    Avarbock, D.4    Rubin, H.5    Barry III, C.E.6
  • 128
    • 33846807242 scopus 로고    scopus 로고
    • Long-chain multiple methyl-branched fatty acid-containing lipids of Mycobacterium tuberculosis: Biosynthesis, transport, regulation and biological activities
    • DOI 10.1016/j.tube.2006.05.003, PII S1472979206000680
    • Jackson M, Stadthagen G, Gicquel B. Long-chain multiple methyl-branched fatty acid-containing lipids of Mycobacterium tuberculosis: biosynthesis, transport, regulation and biological activities. Tuberculosis (Edinb) 2007; 87: 78-86. (Pubitemid 46217257)
    • (2007) Tuberculosis , vol.87 , Issue.2 , pp. 78-86
    • Jackson, M.1    Stadthagen, G.2    Gicquel, B.3
  • 129
    • 80051806726 scopus 로고    scopus 로고
    • Mutation of RNA polymerase b subunit (rpoB) promotes hVISA-to-VISA phenotypic conversion of strain Mu3
    • Matsuo M, Hishinuma T, Katayama Y, Cui L, Kapi M, Hiramatsu K. Mutation of RNA polymerase b subunit (rpoB) promotes hVISA-to-VISA phenotypic conversion of strain Mu3. Antimicrob Agents Chemother 2011; 55: 4188-4195.
    • (2011) Antimicrob Agents Chemother , vol.55 , pp. 4188-4195
    • Matsuo, M.1    Hishinuma, T.2    Katayama, Y.3    Cui, L.4    Kapi, M.5    Hiramatsu, K.6
  • 130
    • 84892761713 scopus 로고    scopus 로고
    • Mycobacterium tuberculosis metabolism and host interaction: Mysteries and paradoxes
    • Ehrt S, Rhee K. Mycobacterium tuberculosis metabolism and host interaction: mysteries and paradoxes. Curr Top Microbiol Immunol 2013; 374: 163-188.
    • (2013) Curr Top Microbiol Immunol , vol.374 , pp. 163-188
    • Ehrt, S.1    Rhee, K.2
  • 131
    • 79951902640 scopus 로고    scopus 로고
    • Mycobacterium tuberculosis and the intimate discourse of a chronic infection
    • Russell DG. Mycobacterium tuberculosis and the intimate discourse of a chronic infection. Immunol Rev 2011; 240: 252-268.
    • (2011) Immunol Rev , vol.240 , pp. 252-268
    • Russell, D.G.1
  • 132
    • 84864357703 scopus 로고    scopus 로고
    • The immunological life cycle of tuberculosis
    • Ernst JD. The immunological life cycle of tuberculosis. Nat Rev Immunol 2012; 12: 581-591.
    • (2012) Nat Rev Immunol , vol.12 , pp. 581-591
    • Ernst, J.D.1
  • 134
    • 84896304657 scopus 로고    scopus 로고
    • Proteomic analysis of purified protein derivative of Mycobacterium tuberculosis
    • Prasad TS, Verma R, Kumar S et al. Proteomic analysis of purified protein derivative of Mycobacterium tuberculosis. Clin Proteomics 2013; 10: 8.
    • (2013) Clin Proteomics , vol.10 , pp. 8
    • Prasad, T.S.1    Verma, R.2    Kumar, S.3
  • 138
    • 28044467549 scopus 로고    scopus 로고
    • Abnormal production of transforming growth factor β and interferon γ by peripheral blood cells of patients with multidrug-resistant pulmonary tuberculosis in Brazil
    • DOI 10.1016/j.jinf.2004.08.035, PII S0163445304002397
    • Castro AZ, Diaz-Bardalez BM, Oliveira EC et al. Abnormal production of transforming growth factor b and interferon c by peripheral blood cells of patients with multidrugresistant pulmonary tuberculosis in Brazil. J Infect 2005; 51: 318-324. (Pubitemid 41683873)
    • (2005) Journal of Infection , vol.51 , Issue.4 , pp. 318-324
    • Castro, A.Z.1    Diaz-Bardalez, B.M.2    Oliveira, E.C.3    Garcia, R.C.4    Afiune, J.B.5    Paschoal, I.A.6    Santos, L.M.B.7
  • 139
    • 77956611547 scopus 로고    scopus 로고
    • Decrease in CD41 CD251 FoxP31 Treg cells after pulmonary resection in the treatment of cavity multidrug-resistant tuberculosis
    • Wu YE, Peng WG, Cai YM et al. Decrease in CD41 CD251 FoxP31 Treg cells after pulmonary resection in the treatment of cavity multidrug-resistant tuberculosis. Int J Infect Dis 2010; 14: e815.
    • (2010) Int J Infect Dis , vol.14
    • Wu, Y.E.1    Peng, W.G.2    Cai, Y.M.3
  • 140
    • 0034041916 scopus 로고    scopus 로고
    • Genetic antagonism and hypermutability in Mycobacterium smegmatis
    • DOI 10.1128/JB.182.12.3331-3335.2000
    • Karunakaran P, Davies J. Genetic antagonism and hypermutability in Mycobacterium smegmatis. J Bacteriol 2000; 182: 3331-3335. (Pubitemid 30341592)
    • (2000) Journal of Bacteriology , vol.182 , Issue.12 , pp. 3331-3335
    • Karunakaran, P.1    Davies, J.2
  • 143
    • 3242776200 scopus 로고    scopus 로고
    • Adaptive point mutation and adaptive amplification pathways in the Escherichia coli lac system: Stress responses producing genetic change
    • DOI 10.1128/JB.186.15.4838-4843.2004
    • Rosenberg SM, Hastings PJ. Adaptive point mutation and adaptive amplification pathways in the Escherichia coli Lac system: stress responses producing genetic change. J Bacteriol 2004; 186: 4838-4843. (Pubitemid 38970807)
    • (2004) Journal of Bacteriology , vol.186 , Issue.15 , pp. 4838-4843
    • Rosenberg, S.M.1    Hastings, P.J.2
  • 144
    • 84888256846 scopus 로고    scopus 로고
    • Elevated mutagenesis does not explain the increased frequency of antibiotic resistant mutants in starved aging colonies
    • Katz S, Hershberg R. Elevated mutagenesis does not explain the increased frequency of antibiotic resistant mutants in starved aging colonies. PLOS Genet 2013; 9: e1003968.
    • (2013) PLOS Genet , vol.9
    • Katz, S.1    Hershberg, R.2
  • 145
    • 84873635856 scopus 로고    scopus 로고
    • Evolutionary potential, cross-stress behavior and the genetic basis of acquired stress resistance in Escherichia coli
    • Dragosits M, Mozhayskiy V, Quinones-Soto S, Park J, Tagkopoulos I. Evolutionary potential, cross-stress behavior and the genetic basis of acquired stress resistance in Escherichia coli. Mol Syst Biol 2013; 9: 643.
    • (2013) Mol Syst Biol , vol.9 , pp. 643
    • Dragosits, M.1    Mozhayskiy, V.2    Quinones-Soto, S.3    Park, J.4    Tagkopoulos, I.5
  • 146
    • 84883412458 scopus 로고    scopus 로고
    • Clinically relevant mutant DNA gyrase alters supercoiling, changes the transcriptome, and confers multidrug resistance
    • Webber MA, Ricci V, Whitehead R et al. Clinically relevant mutant DNA gyrase alters supercoiling, changes the transcriptome, and confers multidrug resistance. MBio 2013; 4: e00273-13.
    • (2013) MBio , vol.4
    • Webber, M.A.1    Ricci, V.2    Whitehead, R.3
  • 147
    • 0030725246 scopus 로고    scopus 로고
    • Ribosylative inactivation of rifampin by Mycobacterium smegmatis is a principal contributor to its low susceptibility to this antibiotic
    • Quan S, Venter H, Dabbs ER. Ribosylative inactivation of rifampin by Mycobacterium smegmatis is a principal contributor to its low susceptibility to this antibiotic. Antimicrob Agents Chemother 1997; 41: 2456-2460. (Pubitemid 27467556)
    • (1997) Antimicrobial Agents and Chemotherapy , vol.41 , Issue.11 , pp. 2456-2460
    • Quan, S.1    Venter, H.2    Dabbs, E.R.3
  • 148
    • 79953279193 scopus 로고    scopus 로고
    • Drug tolerance in replicating mycobacteria mediated by a macrophage-induced efflux mechanism
    • Adams KN, Takaki K, Connolly LE et al. Drug tolerance in replicating mycobacteria mediated by a macrophage-induced efflux mechanism. Cell 2011; 145: 39-53.
    • (2011) Cell , vol.145 , pp. 39-53
    • Adams, K.N.1    Takaki, K.2    Connolly, L.E.3
  • 149
    • 66249092429 scopus 로고    scopus 로고
    • Drug efflux pump deficiency and drug target resistance masking in growing bacteria
    • Fange D, Nilsson K, Tenson T, Ehrenberg M. Drug efflux pump deficiency and drug target resistance masking in growing bacteria. Proc Natl Acad Sci USA 2009; 106: 8215-8220.
    • (2009) Proc Natl Acad Sci USA , vol.106 , pp. 8215-8220
    • Fange, D.1    Nilsson, K.2    Tenson, T.3    Ehrenberg, M.4
  • 150
    • 84880434138 scopus 로고    scopus 로고
    • LC-MS based assay to measure intracellular compound levels in Mycobacterium smegmatis: Linking compound levels to cellular potency
    • Bhat J, Narayan A, Venkatraman J, Chatterji M. LC-MS based assay to measure intracellular compound levels in Mycobacterium smegmatis: Linking compound levels to cellular potency. J Microbiol Methods 2013; 94: 152-158.
    • (2013) J Microbiol Methods , vol.94 , pp. 152-158
    • Bhat, J.1    Narayan, A.2    Venkatraman, J.3    Chatterji, M.4
  • 151
    • 79551718362 scopus 로고    scopus 로고
    • Tuberculosis control has failed in South Africa-time to reappraise strategy
    • Wood R, Lawn SD, Johnstone-Robertson S, Bekker LG. Tuberculosis control has failed in South Africa-time to reappraise strategy. S Afr Med J 2011; 101: 111-114.
    • (2011) S Afr Med J , vol.101 , pp. 111-114
    • Wood, R.1    Lawn, S.D.2    Johnstone-Robertson, S.3    Bekker, L.G.4


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