Mutations outside the rifampicin resistance-determining region associated with rifampicin resistance in Mycobacterium tuberculosis

Journal of Antimicrobial Chemotherapy

Volumn 66, Issue 4, 2011, Pages 730-733

  Siu, Gilman Kit Hang ^a   Zhang, Ying ^b   Lau, Terrence C K ^c   Lau, Ricky W T ^a   Ho, Pak Leung ^a   Yew, Wing Wai ^d   Tsui, Stephen K W ^c   Cheng, Vincent C C ^a   Yuen, Kwok Yung ^a   Yam, Wing Cheong ^a  

^a UNIVERSITY OF HONG KONG   (Hong Kong)

^b JOHNS HOPKINS BLOOMBERG SCHOOL OF PUBLIC HEALTH   (United States)

^c CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

^d GRANTHAM HOSPITAL   (Hong Kong)

Author keywords

Mycobacterial RNA polymerase; Mycobacterium smegmatis; RpoB transformation

Indexed keywords

AMINO ACID; RIFAMPICIN; RNA POLYMERASE BETA SUBUNIT;

AMINO ACID SUBSTITUTION; ANTIBIOTIC RESISTANCE; ANTIBIOTIC SENSITIVITY; ARTICLE; BACTERIUM ISOLATE; BETA CHAIN; CHEMICAL STRUCTURE; DRUG PROTEIN BINDING; GENE MUTATION; GENETIC TRANSFORMATION; MINIMUM INHIBITORY CONCENTRATION; MOLECULAR CLONING; MYCOBACTERIUM SMEGMATIS; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PROMOTER REGION; SEQUENCE ANALYSIS; THERMUS THERMOPHILUS; WILD TYPE;

EID: 79952807087     PISSN: 03057453     EISSN: 14602091     Source Type: Journal    
DOI: 10.1093/jac/dkq519     Document Type: Article

References (10)

1. WHO. Global Tuberculosis Control-Surveillance, Planning, Financing. Geneva, Switzerland: WHO, 2008.
2. Yam WC, Tam CM, Leung CC et al. Direct detection of rifampin-resistant Mycobacterium tuberculosis in respiratory specimens by PCR-DNA sequencing. J Clin Microbiol 2004; 42: 4438-43.
3. Heep M, Brandstatter B, Rieger U et al. Frequency of rpoB mutations inside and outside the cluster I region in rifampin-resistant clinical Mycobacterium tuberculosis isolates. J Clin Microbiol 2001; 39: 107-10.
4. Yuen LK, Leslie D, Coloe PJ. Bacteriological and molecular analysis of rifampin-resistant Mycobacterium tuberculosis strains isolated in Australia. J Clin Microbiol 1999; 37: 3844-50.
5. Clinical and Laboratory Standards Institute. Susceptibility Testing of Mycobacteria, Nocardia and Other Aerobic Actinomycetes: Approved Standard M24-A. CLSI, Wayne, PA, USA, 2003.
6. Garbe TR, Barathi J, Barnini S et al. Transformation of mycobacterial species using hygromycin resistance as selectable marker. Microbiology 1994; 140: 133-8.
7. Wards BJ, Collins DM. Electroporation at elevated temperatures substantially improves transformation efficiency of slow-growing mycobacteria. FEMS Microbiol Lett 1996; 145: 101-5.
8. Artsimovitch I, Vassylyeva MN, Svetlov D et al. Allosteric modulation of the RNA polymerase catalytic reaction is an essential component of transcription control by rifamycins. Cell 2005; 122: 351-63.
9. Kelley LA, Sternberg MJ. Protein structure prediction on the Web: a case study using the Phyre server. Nat Protoc 2009; 4: 363-71.
10. Van Deun A, Martin A, Palomino JC. Diagnosis of drug-resistant tuberculosis: reliability and rapidity of detection. Int J Tuberc Lung Dis 2010; 14: 131-40.