Evolution of high-level ethambutol-resistant tuberculosis through interacting mutations in decaprenylphosphoryl-β-D-Arabinose biosynthetic and utilization pathway genes

Nature Genetics

Volumn 45, Issue 10, 2013, Pages 1190-1197

  Safi, Hassan ^a   Lingaraju, Subramanya ^a   Amin, Anita ^b   Kim, Soyeon ^a   Jones, Marcus ^a   Holmes, Michael ^c   McNeil, Michael ^b   Peterson, Scott N ^c,d,e   Chatterjee, Delphi ^b   Fleischmann, Robert ^c,d,e   Alland, David ^a  

^a RUTGERS NEW JERSEY MEDICAL SCHOOL   (United States)

^b Department of Environmental and Radiological Health Sciences   (United States)

^c J CRAIG VENTER INSTITUTE   (United States)

^d BURNHAM INSTITUTE   (United States)

^e NATIONAL SCIENCE FOUNDATION   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DECAPRENYLPHOSPHORYL BETA DEXTRO ARABINOSE; EMBB PROTEIN; EMBC PROTEIN; ETHAMBUTOL; PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; CODON; GENE EXPRESSION; GENE MUTATION; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; PHYLOGENY; PRIORITY JOURNAL; SINGLE NUCLEOTIDE POLYMORPHISM; TUBERCULOSIS; WILD TYPE;

ANTITUBERCULAR AGENTS; ARABINOSE; DRUG RESISTANCE, MICROBIAL; ETHAMBUTOL; EVOLUTION, MOLECULAR; MICROBIAL SENSITIVITY TESTS; MUTATION; MYCOBACTERIUM TUBERCULOSIS;

MYCOBACTERIUM TUBERCULOSIS;

EID: 84885003827     PISSN: 10614036     EISSN: 15461718     Source Type: Journal    
DOI: 10.1038/ng.2743     Document Type: Article

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