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Volumn 289, Issue 11, 2014, Pages 7470-7482

Collapsin response mediator protein 2 (CRMP2) interacts with N-methyl-D-aspartate (NMDA) receptor and Na+/Ca2+ exchanger and regulates their functional activity

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; EXPERIMENTS; PEPTIDES; SODIUM;

EID: 84896267792     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M113.518472     Document Type: Article
Times cited : (62)

References (50)
  • 1
    • 0043180531 scopus 로고    scopus 로고
    • Excitotoxic and excitoprotective mechanisms. Abundant targets for the prevention and treatment of neurodegenerative disorders
    • Mattson, M. P. (2003) Excitotoxic and excitoprotective mechanisms. Abundant targets for the prevention and treatment of neurodegenerative disorders. Neuromolecular Med. 3, 65-94
    • (2003) Neuromolecular Med. , vol.3 , pp. 65-94
    • Mattson, M.P.1
  • 4
    • 33748804968 scopus 로고    scopus 로고
    • 2 activity: Their neuropharmacological effects and therapeutic importance for the treatment of neurologic disorders
    • DOI 10.1124/pr.58.3.7
    • Farooqui, A. A., Ong, W. Y., and Horrocks, L. A. (2006) Inhibitors of brain phospholipase A2 activity. Their neuropharmacological effects and therapeutic importance for the treatment of neurologic disorders. Pharmacol. Rev. 58, 591-620 (Pubitemid 44403685)
    • (2006) Pharmacological Reviews , vol.58 , Issue.3 , pp. 591-620
    • Farooqui, A.A.1    Ong, W.-Y.2    Horrocks, L.A.3
  • 5
    • 77951607970 scopus 로고    scopus 로고
    • 2+ exchanger degradation occur downstream of calcium deregulation in hippocampal neurons exposed to excitotoxic glutamate
    • 2+ exchanger degradation occur downstream of calcium deregulation in hippocampal neurons exposed to excitotoxic glutamate. J. Neurosci. Res. 88, 1317-1328
    • (2010) J. Neurosci. Res. , vol.88 , pp. 1317-1328
    • Brustovetsky, T.1    Bolshakov, A.2    Brustovetsky, N.3
  • 7
    • 0025331705 scopus 로고
    • Regulation of the intracellular free calcium concentration in single rat dorsal root ganglion neurones in vitro
    • Thayer, S. A., and Miller, R. J. (1990) Regulation of the intracellular free calcium concentration in single rat dorsal root ganglion neurones in vitro. J. Physiol. 425, 85-115 (Pubitemid 20191661)
    • (1990) Journal of Physiology , vol.425 , pp. 85-115
    • Thayer, S.A.1    Miller, R.J.2
  • 8
    • 0029827804 scopus 로고    scopus 로고
    • Mitochondria, calcium regulation, and acute glutamate excitotoxicity in cultured cerebellar granule cells
    • Budd, S. L., and Nicholls, D. G. (1996) Mitochondria, calcium regulation, and acute glutamate excitotoxicity in cultured cerebellar granule cells. J. Neurochem. 67, 2282-2291 (Pubitemid 26392497)
    • (1996) Journal of Neurochemistry , vol.67 , Issue.6 , pp. 2282-2291
    • Budd, S.L.1    Nicholls, D.G.2
  • 9
    • 0027497936 scopus 로고
    • Source specificity of early calcium neurotoxicity in cultured embryonic spinal neurons
    • Tymianski, M., Charlton, M. P., Carlen, P. L., and Tator, C. H. (1993) Source specificity of early calcium neurotoxicity in cultured embryonic spinal neurons. J. Neurosci. 13, 2085-2104 (Pubitemid 23113418)
    • (1993) Journal of Neuroscience , vol.13 , Issue.5 , pp. 2085-2104
    • Tymianski, M.1    Charlton, M.P.2    Carlen, P.L.3    Tator, C.H.4
  • 13
    • 84934436620 scopus 로고    scopus 로고
    • The CRMP family of proteins and their role in Sema3A signaling
    • Schmidt, E. F., and Strittmatter, S. M. (2007) The CRMP family of proteins and their role in Sema3A signaling. Adv. Exp. Med. Biol. 600, 1-11
    • (2007) Adv. Exp. Med. Biol. , vol.600 , pp. 1-11
    • Schmidt, E.F.1    Strittmatter, S.M.2
  • 14
    • 79958282898 scopus 로고    scopus 로고
    • Collapsin response mediator protein-2. An emerging pathologic feature and therapeutic target for neurodisease indications
    • Hensley, K., Venkova, K., Christov, A., Gunning, W., and Park, J. (2011) Collapsin response mediator protein-2. An emerging pathologic feature and therapeutic target for neurodisease indications. Mol. Neurobiol. 43, 180-191
    • (2011) Mol. Neurobiol. , vol.43 , pp. 180-191
    • Hensley, K.1    Venkova, K.2    Christov, A.3    Gunning, W.4    Park, J.5
  • 15
    • 84868642241 scopus 로고    scopus 로고
    • Opening Pandora's jar. A primer on the putative roles of CRMP2 in a panoply of neurodegenerative, sensory and motor neuron, and central disorders
    • Khanna, R., Wilson, S. M., Brittain, J. M., Weimer, J., Sultana, R., Butterfield, A., and Hensley, K. (2012) Opening Pandora's jar. A primer on the putative roles of CRMP2 in a panoply of neurodegenerative, sensory and motor neuron, and central disorders. Future Neurol. 7, 749-771
    • (2012) Future Neurol. , vol.7 , pp. 749-771
    • Khanna, R.1    Wilson, S.M.2    Brittain, J.M.3    Weimer, J.4    Sultana, R.5    Butterfield, A.6    Hensley, K.7
  • 17
    • 0027474291 scopus 로고
    • Intracellular calcium levels during the period of delayed excitotoxicity
    • Dubinsky, J. M. (1993) Intracellular calcium levels during the period of delayed excitotoxicity. J. Neurosci. 13, 623-631
    • (1993) J. Neurosci. , vol.13 , pp. 623-631
    • Dubinsky, J.M.1
  • 18
    • 0000434165 scopus 로고    scopus 로고
    • 2+ loads by mitochondria in cultured rat hippocampal neurons
    • 2+ loads by mitochondria in cultured rat hippocampal neurons. J. Neurophysiol. 76, 1611-1621
    • (1996) J. Neurophysiol. , vol.76 , pp. 1611-1621
    • Wang, G.J.1    Thayer, S.A.2
  • 19
    • 0029788243 scopus 로고    scopus 로고
    • Mitochondrial depolarization in glutamate-stimulated neurons: An early signal specific to excitotoxin exposure
    • White, R. J., and Reynolds, I. J. (1996) Mitochondrial depolarization in glutamate-stimulated neurons. An early signal specific to excitotoxin exposure. J. Neurosci. 16, 5688-5697 (Pubitemid 26293392)
    • (1996) Journal of Neuroscience , vol.16 , Issue.18 , pp. 5688-5697
    • White, R.J.1    Reynolds, I.J.2
  • 25
    • 0022650213 scopus 로고
    • Selective impairment of learning and blockade of long-term potentiation by an N-methyl-D-aspartate receptor antagonist, AP5
    • Morris, R. G., Anderson, E., Lynch, G. S., and Baudry, M. (1986) Selective impairment of learning and blockade of long-term potentiation by an N-methyl-D-aspartate receptor antagonist, AP5. Nature 319, 774-776 (Pubitemid 16145031)
    • (1986) Nature , vol.319 , Issue.6056 , pp. 774-776
    • Morris, R.G.M.1    Anderson, E.2    Lynch, G.S.3    Baudry, M.4
  • 26
    • 34547652875 scopus 로고    scopus 로고
    • NMDA di-heteromeric receptor populations and associated proteins in rat hippocampus
    • DOI 10.1523/JNEUROSCI.2155-07.2007
    • Al-Hallaq, R. A., Conrads, T. P., Veenstra, T. D., and Wenthold, R. J. (2007) NMDA di-heteromeric receptor populations and associated proteins in rat hippocampus. J. Neurosci. 27, 8334-8343 (Pubitemid 47219608)
    • (2007) Journal of Neuroscience , vol.27 , Issue.31 , pp. 8334-8343
    • Al-Hallaq, R.A.1    Conrads, T.P.2    Veenstra, T.D.3    Wenthold, R.J.4
  • 27
    • 33645010267 scopus 로고    scopus 로고
    • Developmental changes in NMDA neurotoxicity reflect developmental changes in subunit composition of NMDA receptors
    • Zhou, M., and Baudry, M. (2006) Developmental changes in NMDA neurotoxicity reflect developmental changes in subunit composition of NMDA receptors. J. Neurosci. 26, 2956-2963
    • (2006) J. Neurosci. , vol.26 , pp. 2956-2963
    • Zhou, M.1    Baudry, M.2
  • 28
    • 33947331063 scopus 로고    scopus 로고
    • NMDA receptor subunits have differential roles in mediating excitotoxic neuronal death both in vitro and in vivo
    • DOI 10.1523/JNEUROSCI.0116-07.2007
    • Liu, Y., Wong, T. P., Aarts, M., Rooyakkers, A., Liu, L., Lai, T. W., Wu, D. C., Lu, J., Tymianski, M., Craig, A. M., and Wang, Y. T. (2007) NMDA receptor subunits have differential roles in mediating excitotoxic neuronal death both in vitro and in vivo. J. Neurosci. 27, 2846-2857 (Pubitemid 46438991)
    • (2007) Journal of Neuroscience , vol.27 , Issue.11 , pp. 2846-2857
    • Liu, Y.1    Tak, P.W.2    Aarts, M.3    Rooyakkers, A.4    Liu, L.5    Ted, W.L.6    Dong, C.W.7    Lu, J.8    Tymianski, M.9    Craig, A.M.10    Yu, T.W.11
  • 29
    • 33646824867 scopus 로고    scopus 로고
    • 1 activation potentiates striatal NMDA receptors by tyrosine phosphorylation-dependent subunit trafficking
    • DOI 10.1523/JNEUROSCI.0792-06.2006
    • Hallett, P. J., Spoelgen, R., Hyman, B. T., Standaert, D. G., and Dunah, A. W. (2006) Dopamine D1 activation potentiates striatal NMDA receptors by tyrosine phosphorylation-dependent subunit trafficking. J. Neurosci. 26, 4690-4700 (Pubitemid 44315370)
    • (2006) Journal of Neuroscience , vol.26 , Issue.17 , pp. 4690-4700
    • Hallett, P.J.1    Spoelgen, R.2    Hyman, B.T.3    Standaert, D.G.4    Dunah, A.W.5
  • 31
    • 84867432306 scopus 로고    scopus 로고
    • CRMP-2 peptide mediated decrease of high and low voltage-activated calcium channels, attenuation of nociceptor excitability, and anti-nociception in a model of AIDS therapy-induced painful peripheral neuropathy
    • Piekarz, A. D., Due, M. R., Khanna, M., Wang, B., Ripsch, M. S., Wang, R., Meroueh, S. O., Vasko, M. R., White, F. A., and Khanna, R. (2012) CRMP-2 peptide mediated decrease of high and low voltage-activated calcium channels, attenuation of nociceptor excitability, and anti-nociception in a model of AIDS therapy-induced painful peripheral neuropathy. Mol. Pain 8, 54
    • (2012) Mol. Pain , vol.8 , pp. 54
    • Piekarz, A.D.1    Due, M.R.2    Khanna, M.3    Wang, B.4    Ripsch, M.S.5    Wang, R.6    Meroueh, S.O.7    Vasko, M.R.8    White, F.A.9    Khanna, R.10
  • 32
    • 0022588238 scopus 로고
    • Na-Ca exchange current in mammalian heart cells
    • Kimura, J., Noma, A., and Irisawa, H. (1986) Na-Ca exchange current in mammalian heart cells. Nature 319, 596-597 (Pubitemid 16110949)
    • (1986) Nature , vol.319 , Issue.6054 , pp. 596-597
    • Kimura, J.1    Noma, A.2    Irisawa, H.3
  • 33
    • 0022587081 scopus 로고
    • Identification of Na-Ca exchange current in single cardiac myocytes
    • Mechmann, S., and Pott, L. (1986) Identification of Na-Ca exchange current in single cardiac myocytes. Nature 319, 597-599 (Pubitemid 16110950)
    • (1986) Nature , vol.319 , Issue.6054 , pp. 597-599
    • Mechmann, S.1    Pott, L.2
  • 34
    • 0033129434 scopus 로고    scopus 로고
    • 2+ exchange current elicited from isolated rabbit ventricular myocytes by voltage ramp and step protocols
    • 2+ exchange current elicited from isolated rabbit ventricular myocytes by voltage ramp and step protocols. Pflugers Arch. 437, 944-954
    • (1999) Pflugers Arch. , vol.437 , pp. 944-954
    • Convery, M.K.1    Hancox, J.C.2
  • 38
    • 67649785237 scopus 로고    scopus 로고
    • Role of cyclophilin D-dependent mitochondrial permeability transition in glutamate-induced calcium deregulation and excitotoxic neuronal death
    • Li, V., Brustovetsky, T., and Brustovetsky, N. (2009) Role of cyclophilin D-dependent mitochondrial permeability transition in glutamate-induced calcium deregulation and excitotoxic neuronal death. Exp. Neurol. 218, 171-182
    • (2009) Exp. Neurol. , vol.218 , pp. 171-182
    • Li, V.1    Brustovetsky, T.2    Brustovetsky, N.3
  • 39
    • 0038143180 scopus 로고    scopus 로고
    • The relationship between free and total calcium concentrations in the matrix of liver and brain mitochondria
    • DOI 10.1074/jbc.M212661200
    • Chalmers, S., and Nicholls, D. G. (2003) The relationship between free and total calcium concentrations in the matrix of liver and brain mitochondria. J. Biol. Chem. 278, 19062-19070 (Pubitemid 36799293)
    • (2003) Journal of Biological Chemistry , vol.278 , Issue.21 , pp. 19062-19070
    • Chalmers, S.1    Nicholls, D.G.2
  • 40
    • 0032827410 scopus 로고    scopus 로고
    • Mitochondrial transport of cations. Channels, exchangers, and permeability transition
    • Bernardi, P. (1999) Mitochondrial transport of cations. Channels, exchangers, and permeability transition. Physiol. Rev. 79, 1127-1155
    • (1999) Physiol. Rev. , vol.79 , pp. 1127-1155
    • Bernardi, P.1
  • 41
    • 0036904733 scopus 로고    scopus 로고
    • 2+ exchangers and contributes to NMDA excitotoxicity
    • 2+ exchangers and contributes to NMDA excitotoxicity. J. Neurochem. 83, 1321-1328
    • (2002) J. Neurochem. , vol.83 , pp. 1321-1328
    • Czyz, A.1    Kiedrowski, L.2
  • 43
    • 26844560187 scopus 로고    scopus 로고
    • 2 toxicity
    • DOI 10.1111/j.1471-4159.2005.03383.x
    • Kowara, R., Chen, Q., Milliken, M., and Chakravarthy, B. (2005) Calpain-mediated truncation of dihydropyrimidinase-like 3 protein (DPYSL3) in response to NMDA and H2O2 toxicity. J. Neurochem. 95, 466-474 (Pubitemid 41457515)
    • (2005) Journal of Neurochemistry , vol.95 , Issue.2 , pp. 466-474
    • Kowara, R.1    Chen, Q.2    Milliken, M.3    Chakravarthy, B.4
  • 44
    • 68049086885 scopus 로고    scopus 로고
    • Calpain-truncated CRMP-3 and -4 contribute to potassium deprivation-induced apoptosis of cerebellar granule neurons
    • Liu, W., Zhou, X. W., Liu, S., Hu, K., Wang, C., He, Q., and Li, M. (2009) Calpain-truncated CRMP-3 and -4 contribute to potassium deprivation-induced apoptosis of cerebellar granule neurons. Proteomics 9, 3712-3728
    • (2009) Proteomics , vol.9 , pp. 3712-3728
    • Liu, W.1    Zhou, X.W.2    Liu, S.3    Hu, K.4    Wang, C.5    He, Q.6    Li, M.7
  • 45
    • 70849088180 scopus 로고    scopus 로고
    • An atypical role for collapsin response mediator protein 2 (CRMP-2) in neurotransmitter release via interaction with presynaptic voltage-gated calcium channels
    • Brittain, J. M., Piekarz, A. D., Wang, Y., Kondo, T., Cummins, T. R., and Khanna, R. (2009) An atypical role for collapsin response mediator protein 2 (CRMP-2) in neurotransmitter release via interaction with presynaptic voltage-gated calcium channels. J. Biol. Chem. 284, 31375-31390
    • (2009) J. Biol. Chem. , vol.284 , pp. 31375-31390
    • Brittain, J.M.1    Piekarz, A.D.2    Wang, Y.3    Kondo, T.4    Cummins, T.R.5    Khanna, R.6
  • 46
    • 84890165973 scopus 로고    scopus 로고
    • Challenging the catechism of therapeutics for chronic neuropathic pain. Targeting CaV2.2 interactions with CRMP2 peptides
    • Feldman, P., and Khanna, R. (2013) Challenging the catechism of therapeutics for chronic neuropathic pain. Targeting CaV2.2 interactions with CRMP2 peptides. Neurosci. Lett. 557, 27-36
    • (2013) Neurosci. Lett. , vol.557 , pp. 27-36
    • Feldman, P.1    Khanna, R.2
  • 47
    • 84874718658 scopus 로고    scopus 로고
    • Suppression of pain-related behavior in two distinct rodent models of peripheral neuropathy by a homopolyarginine-conjugated CRMP2 peptide
    • Ju, W., Li, Q., Allette, Y. M., Ripsch, M. S., White, F. A., and Khanna, R. (2013) Suppression of pain-related behavior in two distinct rodent models of peripheral neuropathy by a homopolyarginine-conjugated CRMP2 peptide. J. Neurochem. 124, 869-879
    • (2013) J. Neurochem. , vol.124 , pp. 869-879
    • Ju, W.1    Li, Q.2    Allette, Y.M.3    Ripsch, M.S.4    White, F.A.5    Khanna, R.6
  • 48
    • 84868092963 scopus 로고    scopus 로고
    • Cdk5-mediated phosphorylation of CRMP-2 enhances its interaction with CaV2.2
    • Brittain, J. M., Wang, Y., Eruvwetere, O., and Khanna, R. (2012) Cdk5-mediated phosphorylation of CRMP-2 enhances its interaction with CaV2.2. FEBS Lett. 586, 3813-3818
    • (2012) FEBS Lett. , vol.586 , pp. 3813-3818
    • Brittain, J.M.1    Wang, Y.2    Eruvwetere, O.3    Khanna, R.4
  • 50
    • 0028256101 scopus 로고
    • Glutamate impairs neuronal calcium extrusion while reducing sodium gradient
    • DOI 10.1016/0896-6273(94)90272-0
    • Kiedrowski, L., Brooker, G., Costa, E., and Wroblewski, J. T. (1994) Glutamate impairs neuronal calcium extrusion while reducing sodium gradient. Neuron 12, 295-300 (Pubitemid 24071295)
    • (1994) Neuron , vol.12 , Issue.2 , pp. 295-300
    • Kiedrowski, L.1    Brooker, G.2    Costa, E.3    Wroblewski, J.T.4


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