Ifenprodil, a NR2B-selective antagonist of NMDA receptor, inhibits reverse Na+/Ca2+ exchanger in neurons

Neuropharmacology

Volumn 63, Issue 6, 2012, Pages 974-982

  Brittain, Matthew K ^a   Brustovetsky, Tatiana ^a   Brittain, Joel M ^a   Khanna, Rajesh ^a   Cummins, Theodore R ^a   Brustovetsky, Nickolay ^a  

^a INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Calcium dysregulation; Glutamate; Na+ Ca 2+ exchanger; Neuron; NMDA receptor

Indexed keywords

2 AMINO 5 PHOSPHONOVALERIC ACID; 4 BENZYL ALPHA (4 HYDROXYPHENYL) BETA METHYL 1 PIPERIDINEPROPANOL; [[[1 (4-BROMOPHENYL)ETHYL]AMINO] (2,3 DIOXO 1,4 DIHYDROQUINOXALIN 5 YL)METHYL]PHOSPHONIC ACID; CALCIUM ION; CO 101244; GLUTAMIC ACID; GRAMICIDIN; IFENPRODIL; MEGLUMINE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR 2A; N METHYL DEXTRO ASPARTIC ACID RECEPTOR 2B; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT; SODIUM CALCIUM EXCHANGE PROTEIN; SODIUM ION; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BRAIN NERVE CELL; CELL AGING; CONTROLLED STUDY; CYTOSOL; DELAYED CALCIUM DYSREGULATION; DRUG EFFICACY; DRUG MECHANISM; EXCITOTOXICITY; GLUTAMATE EXCITOTOXICITY; IN VITRO STUDY; MOLECULAR INTERACTION; NEUROLOGIC DISEASE; NEUROPATHOLOGY; NEUROPHARMACOLOGY; NEWBORN; NONHUMAN; PATCH CLAMP; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; WHOLE CELL;

ANIMALS; BLOTTING, WESTERN; CALCIUM SIGNALING; CELL SURVIVAL; CELLS, CULTURED; EXCITATORY AMINO ACID AGONISTS; EXCITATORY AMINO ACID ANTAGONISTS; HIPPOCAMPUS; MICROSCOPY, FLUORESCENCE; N-METHYLASPARTATE; NEURONS; PATCH-CLAMP TECHNIQUES; PHENOLS; PIPERIDINES; QUINOXALINES; RATS; RECEPTORS, N-METHYL-D-ASPARTATE; SODIUM-CALCIUM EXCHANGER;

EID: 84865232593     PISSN: 00283908     EISSN: 18737064     Source Type: Journal    
DOI: 10.1016/j.neuropharm.2012.07.012     Document Type: Article

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