Calpain-mediated truncation of dihydropyrimidinase-like 3 protein (DPYSL3) in response to NMDA and H2O2 toxicity

Journal of Neurochemistry

Volumn 95, Issue 2, 2005, Pages 466-474

  Kowara, Renata ^a   Chen, Qianfa ^a   Milliken, Melissa ^a   Chakravarthy, Balu ^a  

^a NATIONAL RESEARCH COUNCIL CANADA   (Canada)

Author keywords

Calpain; Collapsin response mediated protein 4; Dihydropyrimidinase related protein 3; Dihydropyrimidinase like protein 3; N methyl D aspartate; Reactive oxygen species

Indexed keywords

ARGININE; CALPAIN; CALPASTATIN; CASPASE 3 INHIBITOR; COLLAPSIN RESPONSE MEDIATOR PROTEIN; DIHYDROPYRIMIDINASE RELATED PROTEIN 3; HYDROGEN PEROXIDE; N METHYL DEXTRO ASPARTIC ACID; PEPTIDE FRAGMENT; PROTEIN; REACTIVE OXYGEN METABOLITE; SERINE; UNCLASSIFIED DRUG; VALINE;

AMINO ACID SEQUENCE; ANIMAL CELL; ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL LYSATE; CONTROLLED STUDY; ENZYME SUBSTRATE; EXCITOTOXICITY; FETUS; NERVE CELL CULTURE; NERVE CELL DIFFERENTIATION; NERVE FIBER GROWTH; NERVE REGENERATION; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN MODIFICATION;

AMINO ACID SEQUENCE; ANIMALS; BLOTTING, WESTERN; CALCIUM; CALPAIN; CASPASE 3; CASPASES; CELLS, CULTURED; DIZOCILPINE MALEATE; ENZYME INHIBITORS; EXCITATORY AMINO ACID AGONISTS; EXCITATORY AMINO ACID ANTAGONISTS; HYDROGEN PEROXIDE; MOLECULAR SEQUENCE DATA; N-METHYLASPARTATE; NERVE TISSUE PROTEINS; NEURONS; OXIDATIVE STRESS; PHOSPHORYLATION; RATS; RATS, SPRAGUE-DAWLEY;

ANURA;

EID: 26844560187     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2005.03383.x     Document Type: Article

References (55)

1. Aarts M. M. and Tymianski M. (2003) Novel treatment of excitotoxicity: targeted disruption of intracellular signaling from glutamate receptors. Biochem. Pharmacol. 66, 877-886.
2. Allani P. K., Sum T., Bhansali S. G., Mukherjee S. K. and Sonee M. (2004) A comparative study of the effect of oxidative stress on the cytoskeleton in human cortical neurons. Toxicol. Appl. Pharmacol. 196, 29-36.
3. Arimura N., Inagaki N., Chihara K., Menager C., Nakamura N., Amano M., Iwamatsu A., Goshima Y. and Kaibuchi K. (2000) Phosphorylation of collapsin response mediator protein-2 by Rho-kinase. Evidence for two separate signaling pathways for growth cone collapse. J. Biol. Chem. 275, 23 973-23 980.
4. Arundine M. and Tymianski M. (2003) Molecular mechanisms of calcium-dependent neurodegenaration in excitotoxicity. Cell Calcium 34, 325-337.
5. Avshalumov M. V. and Rice M. E. (2002) NMDA receptor activation mediates hydrogen peroxide-induced pathophysiology in rat hippocampal slices. J. Neurophysiol. 87, 2896-2903.
6. Bi X., Chang V., Molnar E., McIlhinney R. A. J. and Baudry M. (1996) The C-terminal domain of glutamate receptor subunit 1 is a target for calpain-mediated proteolysis. Neuroscience 73, 903-906.
7. Bowling A. C. and Beal M. F. (1995) Bioenergetic and oxidative stress in neurodegenerative diseases. Mini review. Life Sci. 56, 1151-1171.
8. Bradford M. M. (1976) A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 72, 248-254.
9. Bulliard C., Zurbriggen R., Tornare J., Faty M., Dastoor Z. and Dreyer J.-L. (1997) Purification of a dichlorophenol-indophenol oxidoreductase from rat and bovine synaptic membranes: tight complex association of a glyceraldehyde-3-phosphate dehydrogenase isoform, TOAD64, enolase-γ and aldolase C. Biochem. J. 324, 555-563.
10. Byk T., Dobransky T., Cifuentes-Diaz C. and Sobel A. (1996) Identification and molecular characterization of Unc-33-like phosphoprotein (Ulip), a putative mammalian homolog of the axonal guidance-associated unc-33 gene product. J. Neurosci. 16, 688-701.
11. Byk T., Ozon S. and Sobel A. (1998) The Ulip family phosphoproteins. Common and specific properties. Eur. J. Biochem. 254, 14-24.
12. del Cerro S., Arai A., Kessler M., Bahr B. A., Vanderklish P., Rivera S. and Lynch G. (1994) Stimulation of NMDA receptors activates calpain in cultured hippocampal slices. Neurosci. Lett. 67, 149-152.
13. Chan S. L. and Mattson M. P. (1999) Caspase and calpain substrates: roles in synaptic plasticity and cell death. J. Neurosci. Res. 58, 167-190.
14. Charrier E., Reibel S., Rogemond V., Aguera M., Thomasset N. and Honnorat J. (2003) Collapsin Response Mediator Proteins (CRMPs). Mol. Neurobiol. 28, 51-63.
15. Coyle J. T. and Puttfracken P. (1993) Oxidative stress, glutamate, and neurodegenerative disorders. Science 262, 689-695.
16. Du Y., Bales K. R., Dodel R. C., Hamilton-Byrd E., Horn J. W., Czilli D. L., Simmons L. K., Ni B. and Paul S. M. (1997) Activation of a caspase 3-related cysteine protease is required for glutamate-mediated apoptosis of cultured cerebellar granule neurons. Proc. Natl Acad. Sci. USA 94, 11 657-11 662.
17. Durkin J. P., Tremblay R., Buchan A., Blosser J., Chakravarthy B., Mealing G., Morley P. and Song D. (1996) An early loss in membrane protein kinase C activity precedes the excitatory amino acid-induced death of primary cortical neurons. J. Neurochem. 66, 951-962.
18. Giasson B. I., Bruening W., Durham H. D. and Mushynski W. E. (1999) Activation of stress-activated protein kinases correlates with neurite outgrowth induced by protease inhibition in PC12 cells. J. Neurochem. 72, 1081-1087.
19. Glading A., Lauffenburger D. A. and Wells A. (2002) Cutting to the chase: calpain proteases in cell motility. Trends Cell. Biol. 12, 46-54.
20. Guirland C., Suzuki S., Kojima M., Lu B. and Zheng J. Q. (2004) Lipid rafts mediate chemotropic guidance of nerve growth cones. Neuron 42, 51-62.
21. Hall C., Brown M., Jacobs T., Ferrari G., Cann N., Teo M., Monfriest C. and Lim L. (2001) Collapsin response mediator protein switches RhoA and Rac1 morphology in N1E-115 neuroblastoma cells and is regulated by Rho kinase. J. Biol. Chem. 276, 43 482-43 486.
22. Hewitt K. E., Lesiuk H. J., Tauskela J. S., Morley P. and Durkin J. P. (1998) Selective coupling of μ-calpain activation with NMDA receptor is independent of translocation and autolysis in primary cortical neurons. J. Neurosci. Res. 54, 223-232.
23. Huang Y. and Wang K. K. W. (2001) The calpain family and human disease. Trends Mol. Med. 8, 355-361.
24. Ikonomidou C. and Turski L. (1996) Prevention of trauma-induced neurodegeneration in infant and adult rat brain: glutamate antagonists. Metab. Brain Dis. 11, 125-141.
25. Ishihara I., Minami Y., Nishizaki T., Matsuoka T. and Yamamura H. (2000) Activation of calpain precedes morphological alterations during hydrogen peroxide-induced apoptosis in neuronally differentiated mouse embryonal carcinoma P19 cell line. Neurosci. Lett. 279, 97-100.
26. Laemmli U. K. (1970) Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227, 680-685.
27. 2-induced neuronal apoptosis. J. Neurochem. 73, 1181-1188.
28. Minturn J. E., Fryer H. J., Geschwind D. H. and Hockfield S. (1995) TOAD-64, a gene expressed early in neuronal differentiation in the rat, is related to unc-33, a C. elegans gene involved in axon outgrowth. J. Neurosci. 15, 6757-6766.
29. de la Monte S. M., Neely T. R., Cannon J. and Wands J. R. (2000) Oxidative stress and hypoxia-like injury cause Alzheimer-type molecular abnormalities in central nervous system neurons. Cell. Mol. Life Sci. 57, 1471-1481.
30. Munch G., Gasic-Milenkovic J., Dukic-Stefanovic S., Kuhla B., Heinrich K., Riederer P., Huttunen H. J., Founds H. and Sajithlal G. (2003) Microglial activation induces cell death, inhibits neurite outgrowth and causes neurite retraction of differentiated neuroblastoma cells. Exp. Brain Res. 150, 1-8.
31. Nacher J., Rosell D. R. and McEwan B. (2000) Widespread expression of rat callapsin response-mediated protein 4 in the telencephalon and other areas of the adult rat central nervous system. J. Comp. Neurol. 424, 628-639.
32. Nikonenko I., Jourdain P. and Muller D. (2003) Presynaptic remodeling contributes to activity-dependent synaptogenesis. J. Neuroci. 23, 8498-8505.
33. Quinn C. C., Gray G. E. and Hockfield S. (1999) A family of proteins implicated in axon guidance and outgrowth. J. Neurobiol. 41, 158-164.
34. Quinn C. C., Chen E., Kinjo E. G., Kelly G., Bell A. W., Elliot R. C., McPherson P. S. and Hockfield S. (2003) TUC-4b, a novel TUC family variant, regulates neurite outgrowth and associates with vesicles in the growth cone. J. Neurosci. 23, 2815-2823.
35. Rajgopal Y. and Vemuri M. C. (2002) Calpain activation and alpha-spectrin cleavage in rat brain by ethanol. Neurosci. Lett. 321, 187-191.
36. Rami A. (2003) Ischemic neuronal death in the rat hippocampus: the calpain-calpastatin-caspase hypothesis. Rev. Neurobiol. Dis 13, 75-88.
37. Rialas C. M., Nomizu M., Patterson M., Kleinman H. K., Weston C. A. and Weeks B. S. (2000) Nitric oxide mediates laminin-induced neurite outgrowth in PC12 cells. Exp. Cell Res. 260, 268-276.
38. Robles E., Hittenlocher A. and Gomez T. M. (2003) Filipodial calcium transients regulate growth cone motility and guidance through local activation of calpain. Neuron 38, 597-609.
39. Rosslenbroich V, Dai L., Franken S., Gehrke M., Junghans U., Gieselmann V. and Kappler J. (2003) Subcellular localization of collapsin response mediator proteins to lipid rafts. Biochem. Biophys. Res. Commun. 305, 392-399.
40. Saito K.-I., Elce J. S., Hamos J. E. and Nixon R. A. (1993) Widespread activation of calcium activated neutral proteinase (calpain) in the brain in Alzheimer disease: a potential molecular basis for neuronal degeneration. Proc. Natl Acad. Sci. USA 90, 2628-2632.
41. Sato K. and Kawashima S. (2001) Calpain function in the modulation of signal transduction molecules. Biol. Chem. 382, 743-751.
42. See V. and Loeffler J.-P. (2001) Oxidative stress induces neuronal death by recruiting a protease and phosphatase-gated mechanism. J. Biol. Chem. 276, 35 049-35 059.
43. Shea T. B., Cressman C. M., Spencer M. J., Beermann M. and Nixon R. A. (1995) Enhancement of neurite outgrowth following calpain inhibition is mediated by protein kinase C. J. Neurochem. 65, 517-527.
44. Song D.-K., Malmstrom T., Kater S. B. and Mykles D. L. (1994) Calpain inhibitors block Ca2+-induced suppression of neurite outgrowth in isolated hippocampal pyramidal neurons. J. Neurosci. Res. 39, 474-481.
45. Tauskela J. S., Comas T., Hewitt K., Monette R., Paris J., Hogan M. and Morley P. (2001) Cross-tolerance to otherwise lethal N-methyl-D- aspartate and oxygen-glucose deprivation in preconditioned cortical cultures. Neuroscience 107, 571-584.
46. Tompa P., Buzder-Lantos P., Tantos A., Farkas A., Szilagyi A., Banoczi Z., Hudecz F. and Frierdrich P. (2004) On the sequential determinants of calpain cleavage. J. Biol. Chem. 279, 20 775-20 785.
47. Tremblay R., Chakravarthy B., Hewitt K., Tauskela J., Morley P., Atkinson T. and Durkin J. P. (2000) Transient NMDA receptor inactivation provides long-term protection to cultured cortical neurons from a variety of death signals. J. Neurosci. 20, 7183-7192.
48. Trimm K. R. and Rehder V. (2004) Nitric oxide acts as a slow-down and search signal in developing neurites. Eur. J. Neurosci. 19, 809-818.
49. Tsuji M., Inanami O. and Kuwabara M. (2001) Induction of neurite outgrowth in PC12 cells by alpha-phenyl-N-tert-butylnitron through activation of protein kinase C and the Ras-extracellular signal-regulated kinase pathway. J. Biol. Chem. 276, 32 779-32 785.
50. Vanderklish P. W. and Bahr B. A. (2000) The pathogenic activation of calpain: a marker and mediator of cellular toxicity and disease states. J. Exp. Path. 81, 323-339.
51. Vergun O., Sobolevsky A. I., Yelshansky M. V., Keelan J., Khodorov B. I. and Duchen M. R. (2001) Exploration of the role of reactive oxygen species in glutamate neurotoxicity in rat hippocampal neurons in culture. J. Physiol 531, 147-163.
52. 2 and NO on apoptosis involving activation of p38 mitogen-activated protein kinase and caspase-3. J. Neurosci. Res. 72, 508-519.
53. Wang W., Hou X.-Y., Gao C., Liu Y., Zonh Y.-Y. and Zhang G.-Y. (2003) Regulation of c-Jun N-terminal kinase activation in hydrogen peroxide induced neurotoxicity. J. Neurocytol. 32, 143-151.
54. Wilson M. T., Kissalita W. S. and Keith C. H. (2000) Glutamate-induced changes in the pattern of hippocampal dendrite outgrowth: a role for calcium dependent pathways and the microtubule cytoskeleton. J. Neurobiol. 43, 159-172.
55. 2+/calmodulin- dependent protein kinase II in the post-synaptic density by protein sequencing and mass spectrometry. Biochem. Biophys. Res. Commun. 290, 948-954.