메뉴 건너뛰기




Volumn 346, Issue 2, 2014, Pages 225-236

MUC1 drives epithelial-mesenchymal transition in renal carcinoma through Wnt/β-catenin pathway and interaction with SNAIL promoter

Author keywords

Beta catenin; Epithelial mesenchymal transition; GO 203; MUC1; SNAIL

Indexed keywords

BETA CATENIN; MESSENGER RNA; MUCIN 1; TRANSCRIPTION FACTOR SNAIL; CTNNB1 PROTEIN, HUMAN; MUC1 PROTEIN, HUMAN; SNAIL FAMILY TRANSCRIPTION FACTORS; TRANSCRIPTION FACTOR; WNT PROTEIN;

EID: 84896140889     PISSN: 03043835     EISSN: 18727980     Source Type: Journal    
DOI: 10.1016/j.canlet.2013.12.029     Document Type: Article
Times cited : (78)

References (53)
  • 1
    • 84874743726 scopus 로고    scopus 로고
    • MUC1-C oncoprotein as a target in breast cancer: activation of signaling pathways and therapeutic approaches
    • Kufe D.W. MUC1-C oncoprotein as a target in breast cancer: activation of signaling pathways and therapeutic approaches. Oncogene 2013, 32:1073-1081.
    • (2013) Oncogene , vol.32 , pp. 1073-1081
    • Kufe, D.W.1
  • 2
    • 70450247207 scopus 로고    scopus 로고
    • Mucins in cancer: function, prognosis and therapy
    • Kufe D.W. Mucins in cancer: function, prognosis and therapy. Nat. Rev. Cancer 2009, 9:874-885.
    • (2009) Nat. Rev. Cancer , vol.9 , pp. 874-885
    • Kufe, D.W.1
  • 5
    • 67650999875 scopus 로고    scopus 로고
    • The basics of epithelial-mesenchymal transition
    • Kalluri R., Weinberg R.A. The basics of epithelial-mesenchymal transition. J. Clin. Invest. 2009, 119:1420-1428.
    • (2009) J. Clin. Invest. , vol.119 , pp. 1420-1428
    • Kalluri, R.1    Weinberg, R.A.2
  • 7
    • 81855222097 scopus 로고    scopus 로고
    • Sarcomatoid renal cell carcinoma is an example of epithelial-mesenchymal transition
    • Conant J.L., Peng Z., Evans M.F., Naud S., Cooper K. Sarcomatoid renal cell carcinoma is an example of epithelial-mesenchymal transition. J. Clin. Pathol. 2011, 64:1088-1092.
    • (2011) J. Clin. Pathol. , vol.64 , pp. 1088-1092
    • Conant, J.L.1    Peng, Z.2    Evans, M.F.3    Naud, S.4    Cooper, K.5
  • 8
    • 84859914084 scopus 로고    scopus 로고
    • Sarcomatoid conversion of clear cell renal cell carcinoma in relation to epithelial-to-mesenchymal transition
    • Boström A.K., Möller C., Nilsson E., Elfving P., Axelson H., Johansson M.E. Sarcomatoid conversion of clear cell renal cell carcinoma in relation to epithelial-to-mesenchymal transition. Hum. Pathol. 2012, 43:708-719.
    • (2012) Hum. Pathol. , vol.43 , pp. 708-719
    • Boström, A.K.1    Möller, C.2    Nilsson, E.3    Elfving, P.4    Axelson, H.5    Johansson, M.E.6
  • 9
    • 63049123066 scopus 로고    scopus 로고
    • Transitions between epithelial and mesenchymal states: acquisition of malignant and stem cell traits
    • Polyak K., Weinberg R.A. Transitions between epithelial and mesenchymal states: acquisition of malignant and stem cell traits. Nat. Rev. Cancer 2009, 9:265-273.
    • (2009) Nat. Rev. Cancer , vol.9 , pp. 265-273
    • Polyak, K.1    Weinberg, R.A.2
  • 11
    • 84858288644 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transition in tumor microenvironment
    • Jing Y., Han Z., Zhang S., Liu Y., Wei L. Epithelial-mesenchymal transition in tumor microenvironment. Cell Biosci. 2011, 1.
    • (2011) Cell Biosci. , vol.1
    • Jing, Y.1    Han, Z.2    Zhang, S.3    Liu, Y.4    Wei, L.5
  • 12
    • 80053358029 scopus 로고    scopus 로고
    • Expression of SNAIL and Slug in renal cell carcinoma: E-cadherin repressor SNAIL is associated with cancer invasion and prognosis
    • Mikami S., Katsube K., Oya M., Ishida M., Kosaka T., Mizuno R., Mukai M., Okada Y. Expression of SNAIL and Slug in renal cell carcinoma: E-cadherin repressor SNAIL is associated with cancer invasion and prognosis. Lab Invest. 2011, 91:1443-1458.
    • (2011) Lab Invest. , vol.91 , pp. 1443-1458
    • Mikami, S.1    Katsube, K.2    Oya, M.3    Ishida, M.4    Kosaka, T.5    Mizuno, R.6    Mukai, M.7    Okada, Y.8
  • 15
    • 77958451128 scopus 로고    scopus 로고
    • MUC4 mucin-induced epithelial to mesenchymal transition: a novel mechanism for metastasis of human ovarian cancer cells
    • Ponnusamy M.P., Lakshmanan I., Jain M., Das S., Chakraborty S., Dey P., Batra S.K. MUC4 mucin-induced epithelial to mesenchymal transition: a novel mechanism for metastasis of human ovarian cancer cells. Oncogene 2010, 29:5741-5754.
    • (2010) Oncogene , vol.29 , pp. 5741-5754
    • Ponnusamy, M.P.1    Lakshmanan, I.2    Jain, M.3    Das, S.4    Chakraborty, S.5    Dey, P.6    Batra, S.K.7
  • 16
    • 84858994452 scopus 로고    scopus 로고
    • MUC1-C oncoprotein induces TCF7L2 transcription factor activation and promotes cyclin D1 expression in human breast cancer cells
    • Rajabi H., Ahmad R., Jin C., Kosugi M., Alam M., Joshi M.D., Kufe D. MUC1-C oncoprotein induces TCF7L2 transcription factor activation and promotes cyclin D1 expression in human breast cancer cells. J. Biol. Chem. 2012, 287:10703-10713.
    • (2012) J. Biol. Chem. , vol.287 , pp. 10703-10713
    • Rajabi, H.1    Ahmad, R.2    Jin, C.3    Kosugi, M.4    Alam, M.5    Joshi, M.D.6    Kufe, D.7
  • 17
    • 34250361104 scopus 로고    scopus 로고
    • E-cadherin homophilic ligation inhibits cell growth and epidermal growth factor receptor signaling independently of other cell interactions
    • Perrais M., Chen X., Perez-Moreno M., Gumbiner B.M. E-cadherin homophilic ligation inhibits cell growth and epidermal growth factor receptor signaling independently of other cell interactions. Mol. Biol. Cell 2007, 6:2013-2025.
    • (2007) Mol. Biol. Cell , vol.6 , pp. 2013-2025
    • Perrais, M.1    Chen, X.2    Perez-Moreno, M.3    Gumbiner, B.M.4
  • 18
    • 0035918199 scopus 로고    scopus 로고
    • Transgenic MUC1 interacts with epidermal growth factor receptor and correlates with mitogen-activated protein kinase activation in the mouse mammary gland
    • Schroeder J.A., Thompson M.C., Gardner M.M., Gendler S.J. Transgenic MUC1 interacts with epidermal growth factor receptor and correlates with mitogen-activated protein kinase activation in the mouse mammary gland. J. Biol. Chem. 2001, 276:13057-13064.
    • (2001) J. Biol. Chem. , vol.276 , pp. 13057-13064
    • Schroeder, J.A.1    Thompson, M.C.2    Gardner, M.M.3    Gendler, S.J.4
  • 20
    • 0034079665 scopus 로고    scopus 로고
    • A beta-catenin/engrailed chimera selectively suppresses Wnt signaling
    • Montross W.T., Ji H., McCrea P.D. A beta-catenin/engrailed chimera selectively suppresses Wnt signaling. J. Cell Sci. 2000, 113:1759-1770.
    • (2000) J. Cell Sci. , vol.113 , pp. 1759-1770
    • Montross, W.T.1    Ji, H.2    McCrea, P.D.3
  • 21
    • 0034650207 scopus 로고    scopus 로고
    • TCF is the nuclear effector of the beta-catenin signal that patterns the sea urchin animal-vegetal axis
    • Vonica A., Weng W., Gumbiner B.M., Venuti J.M. TCF is the nuclear effector of the beta-catenin signal that patterns the sea urchin animal-vegetal axis. Dev. Biol. 2000, 217:230-243.
    • (2000) Dev. Biol. , vol.217 , pp. 230-243
    • Vonica, A.1    Weng, W.2    Gumbiner, B.M.3    Venuti, J.M.4
  • 24
    • 84898014554 scopus 로고    scopus 로고
    • MUC1-C oncoprotein activates the ZEB1/miR-200c regulatory loop and epithelial-mesenchymal transition
    • Rajabi H., Alam M., Takahashi H., Kharbanda A., Guha M., Ahmad R., Kufe D. MUC1-C oncoprotein activates the ZEB1/miR-200c regulatory loop and epithelial-mesenchymal transition. Oncogene 2013, 10.1038/onc.2013.114.
    • (2013) Oncogene
    • Rajabi, H.1    Alam, M.2    Takahashi, H.3    Kharbanda, A.4    Guha, M.5    Ahmad, R.6    Kufe, D.7
  • 27
    • 34547092962 scopus 로고    scopus 로고
    • D. Nuclear import of the MUC1-C oncoprotein is mediated by nucleoporin Nup62
    • Leng Y., Cao C., Ren J., Huang L., Chen D., Ito M., Kufe D. D. Nuclear import of the MUC1-C oncoprotein is mediated by nucleoporin Nup62. J. Biol. Chem. 2007, 282:19321-19330.
    • (2007) J. Biol. Chem. , vol.282 , pp. 19321-19330
    • Leng, Y.1    Cao, C.2    Ren, J.3    Huang, L.4    Chen, D.5    Ito, M.6    Kufe, D.7
  • 28
    • 84856797304 scopus 로고    scopus 로고
    • Cooperation, amplification, and feed-back in epithelial-mesenchymal transition
    • de Herreros A.García, Baulida J. Cooperation, amplification, and feed-back in epithelial-mesenchymal transition. Biochim. Biophys. Acta 2012, 1825:223-228.
    • (2012) Biochim. Biophys. Acta , vol.1825 , pp. 223-228
    • de Herreros, A.G.1    Baulida, J.2
  • 31
    • 84879417851 scopus 로고    scopus 로고
    • Sarcomatoid carcinoma represents a complete phenotype with various pathways of epithelial mesenchymal transition
    • Sung C.O., Choi H., Lee K.W., Kim S.H. Sarcomatoid carcinoma represents a complete phenotype with various pathways of epithelial mesenchymal transition. J. Clin. Pathol. 2013, 66:601-606.
    • (2013) J. Clin. Pathol. , vol.66 , pp. 601-606
    • Sung, C.O.1    Choi, H.2    Lee, K.W.3    Kim, S.H.4
  • 34
    • 76349123587 scopus 로고    scopus 로고
    • SNAIL associates with EGR-1 and SP-1 to upregulate transcriptional activation of p15INK4b
    • Hu C.T., Chang T.Y., Cheng C.C., Liu C.S., Wu J.R., Li M.C., Wu W.S. SNAIL associates with EGR-1 and SP-1 to upregulate transcriptional activation of p15INK4b. FEBS J. 2010, 277:1202-1218.
    • (2010) FEBS J. , vol.277 , pp. 1202-1218
    • Hu, C.T.1    Chang, T.Y.2    Cheng, C.C.3    Liu, C.S.4    Wu, J.R.5    Li, M.C.6    Wu, W.S.7
  • 38
    • 8944236091 scopus 로고    scopus 로고
    • Two GC boxes (Sp1 sites) are involved in regulation of the activity of the epithelium-specific MUC1 promoter
    • Kovarik A., Lu P.J., Peat N., Morris J., Taylor-Papadimitriou J. Two GC boxes (Sp1 sites) are involved in regulation of the activity of the epithelium-specific MUC1 promoter. J. Biol. Chem. 1996, 271:18140-18147.
    • (1996) J. Biol. Chem. , vol.271 , pp. 18140-18147
    • Kovarik, A.1    Lu, P.J.2    Peat, N.3    Morris, J.4    Taylor-Papadimitriou, J.5
  • 39
    • 5444269904 scopus 로고    scopus 로고
    • Dual regulation of Snail by GSK-3beta-mediated phosphorylation in control of epithelial-mesenchymal transition
    • Zhou B.P., Deng J., Xia W., Xu J., Li Y.M., Gunduz M., Hung M.C. Dual regulation of Snail by GSK-3beta-mediated phosphorylation in control of epithelial-mesenchymal transition. Nat. Cell Biol. 2004, 10:931-940.
    • (2004) Nat. Cell Biol. , vol.10 , pp. 931-940
    • Zhou, B.P.1    Deng, J.2    Xia, W.3    Xu, J.4    Li, Y.M.5    Gunduz, M.6    Hung, M.C.7
  • 41
    • 50649103964 scopus 로고    scopus 로고
    • Snail promotes Wnt target gene expression and interacts with beta-catenin
    • Stemmer V., de Craene B., Berx G., Behrens J. Snail promotes Wnt target gene expression and interacts with beta-catenin. Oncogene 2008, 37:5075-5080.
    • (2008) Oncogene , vol.37 , pp. 5075-5080
    • Stemmer, V.1    de Craene, B.2    Berx, G.3    Behrens, J.4
  • 42
    • 0030958706 scopus 로고    scopus 로고
    • Interaction of the DF3/MUC1 breast carcinoma-associated antigen and beta-catenin in cell adhesion
    • Yamamoto M., Bharti A., Li Y., Kufe D. Interaction of the DF3/MUC1 breast carcinoma-associated antigen and beta-catenin in cell adhesion. J. Biol. Chem. 1997, 272:12492-12494.
    • (1997) J. Biol. Chem. , vol.272 , pp. 12492-12494
    • Yamamoto, M.1    Bharti, A.2    Li, Y.3    Kufe, D.4
  • 43
    • 28544448610 scopus 로고    scopus 로고
    • MUC1 oncoprotein blocks glycogen synthase kinase 3beta-mediated phosphorylation and degradation of beta-catenin
    • Huang L., Chen D., Liu D., Yin L., Kharbanda S., Kufe D. MUC1 oncoprotein blocks glycogen synthase kinase 3beta-mediated phosphorylation and degradation of beta-catenin. Cancer Res. 2005, 65:10413-10422.
    • (2005) Cancer Res. , vol.65 , pp. 10413-10422
    • Huang, L.1    Chen, D.2    Liu, D.3    Yin, L.4    Kharbanda, S.5    Kufe, D.6
  • 44
    • 0029937975 scopus 로고    scopus 로고
    • A mechanism for inhibition of E-cadherin-mediated cell-cell adhesion by the membrane-associated mucin episialin/MUC1
    • Wesseling J., van der Valk S.W., Hilkens J. A mechanism for inhibition of E-cadherin-mediated cell-cell adhesion by the membrane-associated mucin episialin/MUC1. Mol. Biol Cell 1996, 7:565-577.
    • (1996) Mol. Biol Cell , vol.7 , pp. 565-577
    • Wesseling, J.1    van der Valk, S.W.2    Hilkens, J.3
  • 45
    • 0026623301 scopus 로고
    • Suppression of cellular aggregation by high levels of episialin
    • Ligtenberg M.J., Buijs F., Vos H.L., Hilkens J. Suppression of cellular aggregation by high levels of episialin. Cancer Res. 1992, 52:2318-2324.
    • (1992) Cancer Res. , vol.52 , pp. 2318-2324
    • Ligtenberg, M.J.1    Buijs, F.2    Vos, H.L.3    Hilkens, J.4
  • 47
    • 27744550696 scopus 로고    scopus 로고
    • Regulation of Slug transcription in embryonic ectoderm by beta-catenin-Lef/Tcf and BMP-Smad signaling
    • Sakai D., Tanaka Y., Endo Y., Osumi N., Okamoto H., Wakamatsu Y. Regulation of Slug transcription in embryonic ectoderm by beta-catenin-Lef/Tcf and BMP-Smad signaling. Dev. Growth Differ. 2005, 47:471-482.
    • (2005) Dev. Growth Differ. , vol.47 , pp. 471-482
    • Sakai, D.1    Tanaka, Y.2    Endo, Y.3    Osumi, N.4    Okamoto, H.5    Wakamatsu, Y.6
  • 50
    • 82755195700 scopus 로고    scopus 로고
    • MUC1 protein expression in tumor cells regulates transcription of proinflammatory cytokines by forming a complex with nuclear factor-κB p65 and binding to cytokine promoters: importance of extracellular domain
    • Cascio S., Zhang L., Finn O.J. MUC1 protein expression in tumor cells regulates transcription of proinflammatory cytokines by forming a complex with nuclear factor-κB p65 and binding to cytokine promoters: importance of extracellular domain. J. Biol. Chem. 2011, 286:42248-42256.
    • (2011) J. Biol. Chem. , vol.286 , pp. 42248-42256
    • Cascio, S.1    Zhang, L.2    Finn, O.J.3
  • 52
    • 79960042806 scopus 로고    scopus 로고
    • MUC1-C oncoprotein blocks terminal differentiation of chronic myelogenous leukemia cells by a ROS-mediated mechanism
    • Yin L., Kufe D. MUC1-C oncoprotein blocks terminal differentiation of chronic myelogenous leukemia cells by a ROS-mediated mechanism. Genes Cancer 2011, 2:56-64.
    • (2011) Genes Cancer , vol.2 , pp. 56-64
    • Yin, L.1    Kufe, D.2
  • 53
    • 84860279784 scopus 로고    scopus 로고
    • Targeting cysteine-mediated dimerization of the MUC1-C oncoprotein in human cancer cells
    • Raina D., Ahmad R., Rajabi H., Panchamoorthy G., Kharbanda S., Kufe D. Targeting cysteine-mediated dimerization of the MUC1-C oncoprotein in human cancer cells. Int. J. Oncol. 2012, 5:1643-1649.
    • (2012) Int. J. Oncol. , vol.5 , pp. 1643-1649
    • Raina, D.1    Ahmad, R.2    Rajabi, H.3    Panchamoorthy, G.4    Kharbanda, S.5    Kufe, D.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.