-
1
-
-
0001331879
-
Recycling of E-cadherin: a potential mechanism for regulating cadherin dynamics
-
Le T.L., Yap A.S., Stow J.L. Recycling of E-cadherin: a potential mechanism for regulating cadherin dynamics. J. Cell Biol. 1999, 146:219-232.
-
(1999)
J. Cell Biol.
, vol.146
, pp. 219-232
-
-
Le, T.L.1
Yap, A.S.2
Stow, J.L.3
-
2
-
-
48049121067
-
E-cadherin controls beta-catenin and NF-kappa B transcriptional activity in mesenchymal gene expression
-
Solanas G., Porta-de-la-Riva M., Agustí C., Casagolda D., Sánchez-Aguilera F., Larriba M.J., Pons F., Peiró S., Escrivà M., Muñoz A., Duñach M., García de Herreros A., Baulida J. E-cadherin controls beta-catenin and NF-kappa B transcriptional activity in mesenchymal gene expression. J. Cell Sci. 2008, 121:2224-2234.
-
(2008)
J. Cell Sci.
, vol.121
, pp. 2224-2234
-
-
Solanas, G.1
Porta-de-la-Riva, M.2
Agustí, C.3
Casagolda, D.4
Sánchez-Aguilera, F.5
Larriba, M.J.6
Pons, F.7
Peiró, S.8
Escrivà, M.9
Muñoz, A.10
Duñach, M.11
García de Herreros, A.12
Baulida, J.13
-
3
-
-
70450198396
-
Epithelial-mesenchymal transitions in development and disease
-
Thiery J.P., Acloque H., Huang R.Y., Nieto M.A. Epithelial-mesenchymal transitions in development and disease. Cell 2009, 139:871-890.
-
(2009)
Cell
, vol.139
, pp. 871-890
-
-
Thiery, J.P.1
Acloque, H.2
Huang, R.Y.3
Nieto, M.A.4
-
4
-
-
70349165716
-
Epithelial-mesenchymal transition in cancer metastasis: mechanisms, markers and strategies to overcome drug resistance in the clinic
-
Voulgari A., Pintzas A. Epithelial-mesenchymal transition in cancer metastasis: mechanisms, markers and strategies to overcome drug resistance in the clinic. Biochim. Biophys. Acta 2009, 1796:75-90.
-
(2009)
Biochim. Biophys. Acta
, vol.1796
, pp. 75-90
-
-
Voulgari, A.1
Pintzas, A.2
-
5
-
-
34547620873
-
Kruppel-like factor 8 induces epithelial to mesenchymal transition and epithelial cell invasion
-
Wang X., Zheng M., Liu G., Xia W., McKeown-Longo P.J., Hung M.C., Zhao J. Kruppel-like factor 8 induces epithelial to mesenchymal transition and epithelial cell invasion. Cancer Res. 2007, 67:7184-7193.
-
(2007)
Cancer Res.
, vol.67
, pp. 7184-7193
-
-
Wang, X.1
Zheng, M.2
Liu, G.3
Xia, W.4
McKeown-Longo, P.J.5
Hung, M.C.6
Zhao, J.7
-
6
-
-
0033789680
-
The transcription factor snail is a repressor of E-cadherin gene expression in epithelial tumour cells
-
Batlle E., Sancho E., Francí C., Domínguez D., Monfar M., Baulida J., García de Herreros A. The transcription factor snail is a repressor of E-cadherin gene expression in epithelial tumour cells. Nat. Cell Biol. 2000, 2:84-89.
-
(2000)
Nat. Cell Biol.
, vol.2
, pp. 84-89
-
-
Batlle, E.1
Sancho, E.2
Francí, C.3
Domínguez, D.4
Monfar, M.5
Baulida, J.6
García de Herreros, A.7
-
7
-
-
0033784843
-
The transcription factor snail controls epithelial-mesenchymal transitions by repressing E-cadherin expression
-
Cano A., Pérez-Moreno M.A., Rodrigo I., Locascio A., Blanco M.J., del Barrio M.G., Portillo F., Nieto M.A. The transcription factor snail controls epithelial-mesenchymal transitions by repressing E-cadherin expression. Nat. Cell Biol. 2000, 2:76-83.
-
(2000)
Nat. Cell Biol.
, vol.2
, pp. 76-83
-
-
Cano, A.1
Pérez-Moreno, M.A.2
Rodrigo, I.3
Locascio, A.4
Blanco, M.J.5
del Barrio, M.G.6
Portillo, F.7
Nieto, M.A.8
-
8
-
-
0037086277
-
The SLUG zinc-finger protein represses E-cadherin in breast cancer
-
Hajra K.M., Chen D.Y., Fearon E.R. The SLUG zinc-finger protein represses E-cadherin in breast cancer. Cancer Res. 2002, 62:1613-1618.
-
(2002)
Cancer Res.
, vol.62
, pp. 1613-1618
-
-
Hajra, K.M.1
Chen, D.Y.2
Fearon, E.R.3
-
9
-
-
0034964418
-
The two-handed E box binding zinc finger protein SIP1 downregulates E-cadherin and induces invasion
-
Comijn J., Berx G., Vermassen P., Verschueren K., van Grunsven L., Bruyneel E., Mareel M., Huylebroeck D., van Roy F. The two-handed E box binding zinc finger protein SIP1 downregulates E-cadherin and induces invasion. Mol. Cell 2001, 7:1267-1278.
-
(2001)
Mol. Cell
, vol.7
, pp. 1267-1278
-
-
Comijn, J.1
Berx, G.2
Vermassen, P.3
Verschueren, K.4
van Grunsven, L.5
Bruyneel, E.6
Mareel, M.7
Huylebroeck, D.8
van Roy, F.9
-
10
-
-
20144388095
-
DeltaEF1 is a transcriptional repressor of E-cadherin and regulates epithelial plasticity in breast cancer cells
-
Eger A., Aigner K., Sonderegger S., Dampier B., Oehler S., Schreiber M., Berx G., Cano A., Beug H., Foisner R. DeltaEF1 is a transcriptional repressor of E-cadherin and regulates epithelial plasticity in breast cancer cells. Oncogene 2005, 24:2375-2385.
-
(2005)
Oncogene
, vol.24
, pp. 2375-2385
-
-
Eger, A.1
Aigner, K.2
Sonderegger, S.3
Dampier, B.4
Oehler, S.5
Schreiber, M.6
Berx, G.7
Cano, A.8
Beug, H.9
Foisner, R.10
-
11
-
-
0035920152
-
A new role for E12/E47 in the repression of E-cadherin expression and epithelial-mesenchymal transitions
-
Pérez-Moreno M.A., Locascio A., Rodrigo I., Dhondt G., Portillo F., Nieto M.A., Cano A. A new role for E12/E47 in the repression of E-cadherin expression and epithelial-mesenchymal transitions. J. Biol. Chem. 2001, 276:27424-27431.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 27424-27431
-
-
Pérez-Moreno, M.A.1
Locascio, A.2
Rodrigo, I.3
Dhondt, G.4
Portillo, F.5
Nieto, M.A.6
Cano, A.7
-
12
-
-
84856809222
-
Cdc6 expression represses E-cadherin transcription and activates adjacent replication origins
-
Sideriou M., Zakopoulou R., Evangelou K., Liontos M., Kotsinas A., Rampakakis E., Gagos S., Kahata K., Grabusic K., Gkouskou K., Trougakos I.P., Kolettas E., Georgakilas A.G., Volarevic S., Eliopoulos A.G., Zannis-Hadjopoulos M., Moustakas A., Gorgoulis V.G. Cdc6 expression represses E-cadherin transcription and activates adjacent replication origins. J. Cell Biol. 2011, 195:1123-1140.
-
(2011)
J. Cell Biol.
, vol.195
, pp. 1123-1140
-
-
Sideriou, M.1
Zakopoulou, R.2
Evangelou, K.3
Liontos, M.4
Kotsinas, A.5
Rampakakis, E.6
Gagos, S.7
Kahata, K.8
Grabusic, K.9
Gkouskou, K.10
Trougakos, I.P.11
Kolettas, E.12
Georgakilas, A.G.13
Volarevic, S.14
Eliopoulos, A.G.15
Zannis-Hadjopoulos, M.16
Moustakas, A.17
Gorgoulis, V.G.18
-
13
-
-
34249289041
-
Snail, Zeb and bHLH factors in tumour progression: an alliance against the epithelial phenotype?
-
Peinado H., Olmeda D., Cano A. Snail, Zeb and bHLH factors in tumour progression: an alliance against the epithelial phenotype?. Nat. Rev. Cancer 2007, 7:415-428.
-
(2007)
Nat. Rev. Cancer
, vol.7
, pp. 415-428
-
-
Peinado, H.1
Olmeda, D.2
Cano, A.3
-
14
-
-
79953325707
-
Functional cooperation between Snail1 and Twist in the regulation of ZEB1 expression during epithelial to mesenchymal transition
-
Dave N., Guaita-Esteruelas S., Gutarra S., Frías A., Beltran M., Peiró S., García de Herreros A. Functional cooperation between Snail1 and Twist in the regulation of ZEB1 expression during epithelial to mesenchymal transition. J. Biol. Chem. 2011, 286:12024-12032.
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 12024-12032
-
-
Dave, N.1
Guaita-Esteruelas, S.2
Gutarra, S.3
Frías, A.4
Beltran, M.5
Peiró, S.6
García de Herreros, A.7
-
15
-
-
84855358964
-
Lats2 kinase potentiates Snail1 activity by promoting nuclear retention upon phosphorylation
-
Zhang K., Rodriguez-Aznar E., Yabuta N., Owen R.J., Mingot J.M., Nojima H., Nieto M.A., Longmore G.D. Lats2 kinase potentiates Snail1 activity by promoting nuclear retention upon phosphorylation. EMBO J. 2011, 31:29-43.
-
(2011)
EMBO J.
, vol.31
, pp. 29-43
-
-
Zhang, K.1
Rodriguez-Aznar, E.2
Yabuta, N.3
Owen, R.J.4
Mingot, J.M.5
Nojima, H.6
Nieto, M.A.7
Longmore, G.D.8
-
16
-
-
63049101157
-
The role of the ZEB family of transcription factors in development and disease
-
Vandewalle C., van Roy F., Berx G. The role of the ZEB family of transcription factors in development and disease. Cell Mol. Life Sci. 2009, 66:773-787.
-
(2009)
Cell Mol. Life Sci.
, vol.66
, pp. 773-787
-
-
Vandewalle, C.1
van Roy, F.2
Berx, G.3
-
17
-
-
33747835524
-
Expression of Snail protein in tumor-stroma interface
-
Francí C., Takkunen M., Dave N., Alameda F., Gomez S., Rodríguez R., Escrivà M., Montserrat-Sentís B., Baró T., Garrido M., Bonilla F., Virtanen I., Garcia de Herreros A. Expression of Snail protein in tumor-stroma interface. Oncogene 2006, 25:5134-5144.
-
(2006)
Oncogene
, vol.25
, pp. 5134-5144
-
-
Francí, C.1
Takkunen, M.2
Dave, N.3
Alameda, F.4
Gomez, S.5
Rodríguez, R.6
Escrivà, M.7
Montserrat-Sentís, B.8
Baró, T.9
Garrido, M.10
Bonilla, F.11
Virtanen, I.12
Garcia de Herreros, A.13
-
18
-
-
0037131409
-
Snail induction of epithelial to mesenchymal transition in tumor cells is accompanied by MUC1 repression and ZEB1 expression
-
Guaita S., Puig I., Francí C., Garrido M., Domínguez D., Batlle E., Sancho E., Dedhar S., García de Herreros A., Baulida J. Snail induction of epithelial to mesenchymal transition in tumor cells is accompanied by MUC1 repression and ZEB1 expression. J. Biol. Chem. 2002, 277:39209-39216.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 39209-39216
-
-
Guaita, S.1
Puig, I.2
Francí, C.3
Garrido, M.4
Domínguez, D.5
Batlle, E.6
Sancho, E.7
Dedhar, S.8
García de Herreros, A.9
Baulida, J.10
-
19
-
-
77954854837
-
Snail family regulation and epithelial mesenchymal transitions in breast cancer progression
-
García de Herreros A., Peiró S., Nassour M., Savagner P. Snail family regulation and epithelial mesenchymal transitions in breast cancer progression. J. Mammary. Gland. Biol. Neoplasia 2010, 15:135-147.
-
(2010)
J. Mammary. Gland. Biol. Neoplasia
, vol.15
, pp. 135-147
-
-
García de Herreros, A.1
Peiró, S.2
Nassour, M.3
Savagner, P.4
-
20
-
-
68249092353
-
A SNAIL1-SMAD3/4 transcriptional repressor complex promotes TGF-beta mediated epithelial-mesenchymal transition
-
Vincent T., Neve E.P., Johnson J.R., Kukalev A., Rojo F., Albanell J., Pietras K., Virtanen I., Philipson L., Leopold P.L., Crystal R.G., García de Herreros A., Moustakas A., Pettersson R.F., Fuxe J. A SNAIL1-SMAD3/4 transcriptional repressor complex promotes TGF-beta mediated epithelial-mesenchymal transition. Nat. Cell Biol. 2009, 11:943-950.
-
(2009)
Nat. Cell Biol.
, vol.11
, pp. 943-950
-
-
Vincent, T.1
Neve, E.P.2
Johnson, J.R.3
Kukalev, A.4
Rojo, F.5
Albanell, J.6
Pietras, K.7
Virtanen, I.8
Philipson, L.9
Leopold, P.L.10
Crystal, R.G.11
García de Herreros, A.12
Moustakas, A.13
Pettersson, R.F.14
Fuxe, J.15
-
21
-
-
84856884096
-
The p65 subunit of NF-kB and PARP1 assist Snail1 in activating Fibronectin transcription
-
Stanisavljevic J., Porta-de-la-Riva M., Batlle R., García de Herreros A., Baulida J. The p65 subunit of NF-kB and PARP1 assist Snail1 in activating Fibronectin transcription. J. Cell. Sci. 2011, 124:4161-4171.
-
(2011)
J. Cell. Sci.
, vol.124
, pp. 4161-4171
-
-
Stanisavljevic, J.1
Porta-de-la-Riva, M.2
Batlle, R.3
García de Herreros, A.4
Baulida, J.5
-
22
-
-
2942707848
-
Twist, a master regulator of morphogenesis, plays an essential role in tumor metastasis
-
Yang J., Mani S.A., Donaher J.L., Ramaswamy S., Itzykson R.A., Come C., Savagner P., Gitelman I., Richardson A., Weinberg R.A. Twist, a master regulator of morphogenesis, plays an essential role in tumor metastasis. Cell 2004, 117:927-939.
-
(2004)
Cell
, vol.117
, pp. 927-939
-
-
Yang, J.1
Mani, S.A.2
Donaher, J.L.3
Ramaswamy, S.4
Itzykson, R.A.5
Come, C.6
Savagner, P.7
Gitelman, I.8
Richardson, A.9
Weinberg, R.A.10
-
23
-
-
77957583439
-
Bmi1 is essential in Twist1-induced epithelial-mesenchymal transition
-
Yang M.H., Hsu D.S., Wang H.W., Wang H.J., Lan H.Y., Yang W.H., Huang C.H., Kao S.Y., Tzeng C.H., Tai S.K., Chang S.Y., Lee O.K., Wu K.J. Bmi1 is essential in Twist1-induced epithelial-mesenchymal transition. Nat. Cell Biol. 2010, 12:982-992.
-
(2010)
Nat. Cell Biol.
, vol.12
, pp. 982-992
-
-
Yang, M.H.1
Hsu, D.S.2
Wang, H.W.3
Wang, H.J.4
Lan, H.Y.5
Yang, W.H.6
Huang, C.H.7
Kao, S.Y.8
Tzeng, C.H.9
Tai, S.K.10
Chang, S.Y.11
Lee, O.K.12
Wu, K.J.13
-
24
-
-
57749114754
-
HMGA2 and Smads co-regulate SNAIL1 expression during induction of epithelial-to-mesenchymal transition
-
Thuault S., Tan E.J., Peinado H., Cano A., Heldin C.H., Moustakas A. HMGA2 and Smads co-regulate SNAIL1 expression during induction of epithelial-to-mesenchymal transition. J. Biol. Chem. 2008, 283:33437-33446.
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 33437-33446
-
-
Thuault, S.1
Tan, E.J.2
Peinado, H.3
Cano, A.4
Heldin, C.H.5
Moustakas, A.6
-
25
-
-
0038756636
-
Transforming growth factor beta-1 induces snail transcription factor in epithelial cell lines: mechanisms for epithelial mesenchymal transitions
-
Peinado H., Quintanilla M., Cano A. Transforming growth factor beta-1 induces snail transcription factor in epithelial cell lines: mechanisms for epithelial mesenchymal transitions. J. Biol. Chem. 2003, 278:21113-21123.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 21113-21123
-
-
Peinado, H.1
Quintanilla, M.2
Cano, A.3
-
26
-
-
58649097517
-
Role of Ras signaling in the induction of snail by transforming growth factor-beta
-
Horiguchi K., Shirakihara T., Nakano A., Imamura T., Miyazono K., Saitoh M. Role of Ras signaling in the induction of snail by transforming growth factor-beta. J. Biol. Chem. 2009, 284:245-253.
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 245-253
-
-
Horiguchi, K.1
Shirakihara, T.2
Nakano, A.3
Imamura, T.4
Miyazono, K.5
Saitoh, M.6
-
27
-
-
84855729906
-
A p53/miRNA-34 axis regulates Snail1-dependent cancer cell epithelial-mesenchymal transition
-
Kim N.H., Kim H.S., Li X.Y., Lee I., Choi H.S., Kang S.E., Cha S.Y., Ryu J.K., Yoon D., Fearon E.R., Rowe R.G., Lee S., Maher C.A., Weiss S.J., Yook J.I. A p53/miRNA-34 axis regulates Snail1-dependent cancer cell epithelial-mesenchymal transition. J. Cell Biol. 2011, 195:417-433.
-
(2011)
J. Cell Biol.
, vol.195
, pp. 417-433
-
-
Kim, N.H.1
Kim, H.S.2
Li, X.Y.3
Lee, I.4
Choi, H.S.5
Kang, S.E.6
Cha, S.Y.7
Ryu, J.K.8
Yoon, D.9
Fearon, E.R.10
Rowe, R.G.11
Lee, S.12
Maher, C.A.13
Weiss, S.J.14
Yook, J.I.15
-
28
-
-
34447136813
-
A 3' enhancer controls snail expression in melanoma cells
-
Palmer M.B., Majumder P., Green M.R., Wade P.A., Boss J.M. A 3' enhancer controls snail expression in melanoma cells. Cancer Res. 2007, 67:6113-6120.
-
(2007)
Cancer Res.
, vol.67
, pp. 6113-6120
-
-
Palmer, M.B.1
Majumder, P.2
Green, M.R.3
Wade, P.A.4
Boss, J.M.5
-
29
-
-
77957243921
-
Long noncoding RNAs with enhancer-like function in human cells
-
Orom U.A., Derrien T., Beringer M., Gumireddy K., Gardini A., Bussotti G., Lai F., Zytnicki M., Notredame C., Huang Q., Guigo R., Shiekhattar R. Long noncoding RNAs with enhancer-like function in human cells. Cell 2010, 143:46-58.
-
(2010)
Cell
, vol.143
, pp. 46-58
-
-
Orom, U.A.1
Derrien, T.2
Beringer, M.3
Gumireddy, K.4
Gardini, A.5
Bussotti, G.6
Lai, F.7
Zytnicki, M.8
Notredame, C.9
Huang, Q.10
Guigo, R.11
Shiekhattar, R.12
-
30
-
-
5444269904
-
Dual regulation of snail by GSK-3beta-mediated phosphorylation in control of epithelial-mesenchymal transition
-
Zhou B.P., Deng J., Xia W., Xu J., Li Y.M., Gunduz M., Hung M.C. Dual regulation of snail by GSK-3beta-mediated phosphorylation in control of epithelial-mesenchymal transition. Nat. Cell Biol. 2004, 6:931-940.
-
(2004)
Nat. Cell Biol.
, vol.6
, pp. 931-940
-
-
Zhou, B.P.1
Deng, J.2
Xia, W.3
Xu, J.4
Li, Y.M.5
Gunduz, M.6
Hung, M.C.7
-
31
-
-
33751514601
-
A Wnt-Axin2-GSK3beta cascade regulates Snail1 activity in breast cancer cells
-
Yook J.I., Li X.Y., Ota I., Hu C., Kim H.S., Kim N.H., Cha S.Y., Ryu J.K., Choi Y.J., Kim J., Fearon E.R., Weiss S.J. A Wnt-Axin2-GSK3beta cascade regulates Snail1 activity in breast cancer cells. Nat. Cell Biol. 2006, 8:1398-1406.
-
(2006)
Nat. Cell Biol.
, vol.8
, pp. 1398-1406
-
-
Yook, J.I.1
Li, X.Y.2
Ota, I.3
Hu, C.4
Kim, H.S.5
Kim, N.H.6
Cha, S.Y.7
Ryu, J.K.8
Choi, Y.J.9
Kim, J.10
Fearon, E.R.11
Weiss, S.J.12
-
32
-
-
16844377441
-
Pak1 phosphorylation of snail, a master regulator of epithelial-to-mesenchyme transition, modulates snail's subcellular localization and functions
-
Yang Z., Rayala S., Nguyen D., Vadlamudi R.K., Chen S., Kumar R. Pak1 phosphorylation of snail, a master regulator of epithelial-to-mesenchyme transition, modulates snail's subcellular localization and functions. Cancer Res. 2005, 65:3179-3184.
-
(2005)
Cancer Res.
, vol.65
, pp. 3179-3184
-
-
Yang, Z.1
Rayala, S.2
Nguyen, D.3
Vadlamudi, R.K.4
Chen, S.5
Kumar, R.6
-
33
-
-
78449288408
-
Snail1 is stabilized by O-GlcNAc modification in hyperglycaemic condition
-
Park S.Y., Kim H.S., Kim N.H., Ji S., Cha S.Y., Kang J.G., Ota I., Shimada K., Konishi N., Nam H.W., Hong S.W., Yang W.H., Roth J., Yook J.I., Cho J.W. Snail1 is stabilized by O-GlcNAc modification in hyperglycaemic condition. EMBO J. 2010, 29:3787-3796.
-
(2010)
EMBO J.
, vol.29
, pp. 3787-3796
-
-
Park, S.Y.1
Kim, H.S.2
Kim, N.H.3
Ji, S.4
Cha, S.Y.5
Kang, J.G.6
Ota, I.7
Shimada, K.8
Konishi, N.9
Nam, H.W.10
Hong, S.W.11
Yang, W.H.12
Roth, J.13
Yook, J.I.14
Cho, J.W.15
-
34
-
-
80054899318
-
Poly(ADP-ribose)-dependent regulation of Snail1 protein stability
-
Rodríguez M.I., González-Flores A., Dantzer F., Collard J., García de Herreros A., Oliver F.J. Poly(ADP-ribose)-dependent regulation of Snail1 protein stability. Oncogene 2011, 30:4365-4372.
-
(2011)
Oncogene
, vol.30
, pp. 4365-4372
-
-
Rodríguez, M.I.1
González-Flores, A.2
Dantzer, F.3
Collard, J.4
García de Herreros, A.5
Oliver, F.J.6
-
35
-
-
77950505906
-
The hypoxia-controlled FBXL14 ubiquitin ligase targets SNAIL1 for proteasome degradation
-
Viñas-Castells R., Beltran M., Valls G., Gómez I., García J.M., Montserrat-Sentís B., Baulida J., Bonilla F., García de Herreros A., Díaz V.M. The hypoxia-controlled FBXL14 ubiquitin ligase targets SNAIL1 for proteasome degradation. J. Biol. Chem. 2010, 285:3794-3805.
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 3794-3805
-
-
Viñas-Castells, R.1
Beltran, M.2
Valls, G.3
Gómez, I.4
García, J.M.5
Montserrat-Sentís, B.6
Baulida, J.7
Bonilla, F.8
García de Herreros, A.9
Díaz, V.M.10
-
36
-
-
79960283982
-
The F-box protein Ppa is a common regulator of core EMT factors Twist, Snail, Slug, and Sip1
-
Lander R., Nordin K., LaBonne C. The F-box protein Ppa is a common regulator of core EMT factors Twist, Snail, Slug, and Sip1. J. Cell Biol. 2011, 194:17-25.
-
(2011)
J. Cell Biol.
, vol.194
, pp. 17-25
-
-
Lander, R.1
Nordin, K.2
LaBonne, C.3
-
37
-
-
0038324070
-
Regulation of Smad signaling through a differential recruitment of coactivators and corepressors by ZEB proteins
-
Postigo A.A., Depp J.L., Taylor J.J., Kroll K.L. Regulation of Smad signaling through a differential recruitment of coactivators and corepressors by ZEB proteins. EMBO J. 2003, 22:2453-2462.
-
(2003)
EMBO J.
, vol.22
, pp. 2453-2462
-
-
Postigo, A.A.1
Depp, J.L.2
Taylor, J.J.3
Kroll, K.L.4
-
38
-
-
27444442397
-
Pc2-mediated sumoylation of Smad-interacting protein 1 attenuates transcriptional repression of E-cadherin
-
Long J., Zuo D., Park M. Pc2-mediated sumoylation of Smad-interacting protein 1 attenuates transcriptional repression of E-cadherin. J. Biol. Chem. 2005, 280:35477-35489.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 35477-35489
-
-
Long, J.1
Zuo, D.2
Park, M.3
-
39
-
-
77954167982
-
Transcriptional crosstalk between TGFbeta and stem cell pathways in tumor cell invasion: role of EMT promoting Smad complexes
-
Fuxe J., Vincent T., García de Herreros A. Transcriptional crosstalk between TGFbeta and stem cell pathways in tumor cell invasion: role of EMT promoting Smad complexes. Cell Cycle 2010, 9.
-
(2010)
Cell Cycle
, vol.9
-
-
Fuxe, J.1
Vincent, T.2
García de Herreros, A.3
-
40
-
-
0345736990
-
Downregulation of caveolin-1 function by EGF leads to the loss of E-cadherin, increased transcriptional activity of beta-catenin, and enhanced tumor cell invasion
-
Lu Z., Ghosh S., Wang Z., Hunter T. Downregulation of caveolin-1 function by EGF leads to the loss of E-cadherin, increased transcriptional activity of beta-catenin, and enhanced tumor cell invasion. Cancer Cell 2003, 4:499-515.
-
(2003)
Cancer Cell
, vol.4
, pp. 499-515
-
-
Lu, Z.1
Ghosh, S.2
Wang, Z.3
Hunter, T.4
-
41
-
-
33747625686
-
Hepatocyte growth factor induces cell scattering through MAPK/Egr-1-mediated upregulation of Snail
-
Grotegut S., von Schweinitz D., Christofori G., Lehembre F. Hepatocyte growth factor induces cell scattering through MAPK/Egr-1-mediated upregulation of Snail. EMBO J. 2006, 25:3534-3545.
-
(2006)
EMBO J.
, vol.25
, pp. 3534-3545
-
-
Grotegut, S.1
von Schweinitz, D.2
Christofori, G.3
Lehembre, F.4
-
42
-
-
69249209681
-
Numb regulates cell-cell adhesion and polarity in response to tyrosine kinase signalling
-
Wang Z., Sandiford S., Wu C., Li S.S. Numb regulates cell-cell adhesion and polarity in response to tyrosine kinase signalling. EMBO J. 2009, 28:2360-2373.
-
(2009)
EMBO J.
, vol.28
, pp. 2360-2373
-
-
Wang, Z.1
Sandiford, S.2
Wu, C.3
Li, S.S.4
-
43
-
-
34548496683
-
Differential regulation of epithelial and mesenchymal markers by deltaEF1 proteins in epithelial mesenchymal transition induced by TGF-beta
-
Shirakihara T., Saitoh M., Miyazono K. Differential regulation of epithelial and mesenchymal markers by deltaEF1 proteins in epithelial mesenchymal transition induced by TGF-beta. Mol. Biol. Cell 2007, 18:3533-3544.
-
(2007)
Mol. Biol. Cell
, vol.18
, pp. 3533-3544
-
-
Shirakihara, T.1
Saitoh, M.2
Miyazono, K.3
-
44
-
-
36349011403
-
Activation of NF-kappaB by Akt upregulates snail expression and induces epithelium mesenchyme transition
-
Julien S., Puig I., Caretti E., Bonaventure J., Nelles L., van Roy F., Dargemont C., De Herreros A.G., Bellacosa A., Larue L. Activation of NF-kappaB by Akt upregulates snail expression and induces epithelium mesenchyme transition. Oncogene 2007, 26:7445-7456.
-
(2007)
Oncogene
, vol.26
, pp. 7445-7456
-
-
Julien, S.1
Puig, I.2
Caretti, E.3
Bonaventure, J.4
Nelles, L.5
van Roy, F.6
Dargemont, C.7
De Herreros, A.G.8
Bellacosa, A.9
Larue, L.10
-
45
-
-
65349092794
-
Stabilization of snail by NF-kappaB is required for inflammation-induced cell migration and invasion
-
Wu Y., Deng J., Rychahou P.G., Qiu S., Evers B.M., Zhou B.P. Stabilization of snail by NF-kappaB is required for inflammation-induced cell migration and invasion. Cancer Cell 2009, 15:416-428.
-
(2009)
Cancer Cell
, vol.15
, pp. 416-428
-
-
Wu, Y.1
Deng, J.2
Rychahou, P.G.3
Qiu, S.4
Evers, B.M.5
Zhou, B.P.6
-
46
-
-
41149112564
-
A natural antisense transcript regulates Zeb2/Sip1 gene expression during Snail1-induced epithelial-mesenchymal transition
-
Beltran M., Puig I., Peña C., García J.M., Álvarez A.B., Peña R., Bonilla F., García de Herreros A. A natural antisense transcript regulates Zeb2/Sip1 gene expression during Snail1-induced epithelial-mesenchymal transition. Genes Dev. 2008, 22:756-769.
-
(2008)
Genes Dev.
, vol.22
, pp. 756-769
-
-
Beltran, M.1
Puig, I.2
Peña, C.3
García, J.M.4
Álvarez, A.B.5
Peña, R.6
Bonilla, F.7
García de Herreros, A.8
-
47
-
-
4644229397
-
The transcription factor SNAIL represses vitamin D receptor expression and responsiveness in human colon cancer
-
Pàlmer H.G., Larriba M.J., García J.M., Ordúñez-Morán P., Peña C., Peiró S., Puig I., Rodríguez R., de la Fuente R., Bernad A., Pollan M., Bonilla F., Gamallo C., García de Herreros A., Muñoz A. The transcription factor SNAIL represses vitamin D receptor expression and responsiveness in human colon cancer. Nat. Med. 2004, 10:917-919.
-
(2004)
Nat. Med.
, vol.10
, pp. 917-919
-
-
Pàlmer, H.G.1
Larriba, M.J.2
García, J.M.3
Ordúñez-Morán, P.4
Peña, C.5
Peiró, S.6
Puig, I.7
Rodríguez, R.8
de la Fuente, R.9
Bernad, A.10
Pollan, M.11
Bonilla, F.12
Gamallo, C.13
García de Herreros, A.14
Muñoz, A.15
-
48
-
-
33645909102
-
Snail1 transcriptional repressor binds to its own promoter and controls its expression
-
Peiró S., Escrivà M., Puig I., Barberà M.J., Dave N., Herranz N., Larriba M.J., Takkunen M., Francí C., Muñoz A., Virtanen I., Baulida J., García de Herreros A. Snail1 transcriptional repressor binds to its own promoter and controls its expression. Nucleic Acids Res. 2006, 34:2077-2084.
-
(2006)
Nucleic Acids Res.
, vol.34
, pp. 2077-2084
-
-
Peiró, S.1
Escrivà, M.2
Puig, I.3
Barberà, M.J.4
Dave, N.5
Herranz, N.6
Larriba, M.J.7
Takkunen, M.8
Francí, C.9
Muñoz, A.10
Virtanen, I.11
Baulida, J.12
García de Herreros, A.13
-
49
-
-
0034676456
-
Feedback control of intercellular signalling in development
-
Freeman M. Feedback control of intercellular signalling in development. Nature 2000, 408:313-319.
-
(2000)
Nature
, vol.408
, pp. 313-319
-
-
Freeman, M.1
-
50
-
-
36849002930
-
The transcription factor snail mediates epithelial to mesenchymal transitions by repression of estrogen receptor-alpha
-
Dhasarathy A., Kajita M., Wade P.A. The transcription factor snail mediates epithelial to mesenchymal transitions by repression of estrogen receptor-alpha. Mol. Endocrinol. 2007, 21:2907-2918.
-
(2007)
Mol. Endocrinol.
, vol.21
, pp. 2907-2918
-
-
Dhasarathy, A.1
Kajita, M.2
Wade, P.A.3
-
51
-
-
0037453706
-
MTA3, a Mi-2/NuRD complex subunit, regulates an invasive growth pathway in breast cancer
-
Fujita N., Jaye D.L., Kajita M., Geigerman C., Moreno C.S., Wade P.A. MTA3, a Mi-2/NuRD complex subunit, regulates an invasive growth pathway in breast cancer. Cell 2003, 113:207-219.
-
(2003)
Cell
, vol.113
, pp. 207-219
-
-
Fujita, N.1
Jaye, D.L.2
Kajita, M.3
Geigerman, C.4
Moreno, C.S.5
Wade, P.A.6
-
52
-
-
84860773704
-
An epistatic mini-circuitry between the transcription factors Snail and HNF4α controls liver stem cell and hepatocyte features exhorting opposite regulation on stemness-inhibiting microRNAs, Cell Death Differ
-
in press doi10.138/cdd2011.175.
-
F. Garibaldi, C. Cicchini, A. Coniglaro, L. Santangelo, A.M. Cozzolino, G. Grassi, A. Marchetti, M. Tripodi, L. Amicone. An epistatic mini-circuitry between the transcription factors Snail and HNF4α controls liver stem cell and hepatocyte features exhorting opposite regulation on stemness-inhibiting microRNAs, Cell Death Differ. in press doi10.138/cdd2011.175.
-
-
-
Garibaldi, F.1
Cicchini, C.2
Coniglaro, A.3
Santangelo, L.4
Cozzolino, A.M.5
Grassi, G.6
Marchetti, A.7
Tripodi, M.8
Amicone, L.9
-
53
-
-
80052730533
-
Reciprocal repression between Sox3 and snail transcription factors defines embryonic territories at gastrulation
-
Acloque H., Ocana O.H., Matheu A., Rizzoti K., Wise C., Lovell-Badge R., Nieto M.A. Reciprocal repression between Sox3 and snail transcription factors defines embryonic territories at gastrulation. Dev. Cell 2011, 21:546-558.
-
(2011)
Dev. Cell
, vol.21
, pp. 546-558
-
-
Acloque, H.1
Ocana, O.H.2
Matheu, A.3
Rizzoti, K.4
Wise, C.5
Lovell-Badge, R.6
Nieto, M.A.7
-
54
-
-
33750358078
-
Genetic profiling of epithelial cells expressing E-cadherin repressors reveals a distinct role for Snail, Slug, and E47 factors in epithelial-mesenchymal transition
-
Moreno-Bueno G., Cubillo E., Sarrio D., Peinado H., Rodríguez-Pinilla S.M., Villa S., Bolós V., Jordà M., Fabra A., Portillo F., Palacios J., Cano A. Genetic profiling of epithelial cells expressing E-cadherin repressors reveals a distinct role for Snail, Slug, and E47 factors in epithelial-mesenchymal transition. Cancer Res. 2006, 66:9543-9556.
-
(2006)
Cancer Res.
, vol.66
, pp. 9543-9556
-
-
Moreno-Bueno, G.1
Cubillo, E.2
Sarrio, D.3
Peinado, H.4
Rodríguez-Pinilla, S.M.5
Villa, S.6
Bolós, V.7
Jordà, M.8
Fabra, A.9
Portillo, F.10
Palacios, J.11
Cano, A.12
-
55
-
-
33747894237
-
SPARC represses E-cadherin and induces mesenchymal transition during melanoma development
-
Robert G., Gaggioli C., Bailet O., Chavey C., Abbe P., Aberdam E., Sabatie E., Cano A., Garcia de H.A., Ballotti R., Tartare-Deckert S. SPARC represses E-cadherin and induces mesenchymal transition during melanoma development. Cancer Res. 2006, 66:7516-7523.
-
(2006)
Cancer Res.
, vol.66
, pp. 7516-7523
-
-
Robert, G.1
Gaggioli, C.2
Bailet, O.3
Chavey, C.4
Abbe, P.5
Aberdam, E.6
Sabatie, E.7
Cano, A.8
Garcia de, H.A.9
Ballotti, R.10
Tartare-Deckert, S.11
-
56
-
-
9144247129
-
Loss of E-cadherin leads to upregulation of NFkappaB activity in malignant melanoma
-
Kuphal S., Poser I., Jobin C., Hellerbrand C., Bosserhoff A.K. Loss of E-cadherin leads to upregulation of NFkappaB activity in malignant melanoma. Oncogene 2004, 23:8509-8519.
-
(2004)
Oncogene
, vol.23
, pp. 8509-8519
-
-
Kuphal, S.1
Poser, I.2
Jobin, C.3
Hellerbrand, C.4
Bosserhoff, A.K.5
-
57
-
-
43049103824
-
The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1
-
Gregory P.A., Bert A.G., Paterson E.L., Barry S.C., Tsykin A., Farshid G., Vadas M.A., Khew-Goodall Y., Goodall G.J. The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1. Nat. Cell Biol. 2008, 10:593-601.
-
(2008)
Nat. Cell Biol.
, vol.10
, pp. 593-601
-
-
Gregory, P.A.1
Bert, A.G.2
Paterson, E.L.3
Barry, S.C.4
Tsykin, A.5
Farshid, G.6
Vadas, M.A.7
Khew-Goodall, Y.8
Goodall, G.J.9
-
58
-
-
41649091906
-
The miR-200 family determines the epithelial phenotype of cancer cells by targeting the E-cadherin repressors ZEB1 and ZEB2
-
Park S.M., Gaur A.B., Lengyel E., Peter M.E. The miR-200 family determines the epithelial phenotype of cancer cells by targeting the E-cadherin repressors ZEB1 and ZEB2. Genes Dev. 2008, 22:894-907.
-
(2008)
Genes Dev.
, vol.22
, pp. 894-907
-
-
Park, S.M.1
Gaur, A.B.2
Lengyel, E.3
Peter, M.E.4
-
59
-
-
73049110243
-
The EMT-activator ZEB1 promotes tumorigenicity by repressing stemness-inhibiting microRNAs
-
Wellner U., Schubert J., Burk U.C., Schmalhofer O., Zhu F., Sonntag A., Waldvogel B., Vannier C., Darling D., zur H.A., Brunton V.G., Morton J., Sansom O., Schuler J., Stemmler M.P., Herzberger C., Hopt U., Keck T., Brabletz S., Brabletz T. The EMT-activator ZEB1 promotes tumorigenicity by repressing stemness-inhibiting microRNAs. Nat. Cell Biol. 2009, 11:1487-1495.
-
(2009)
Nat. Cell Biol.
, vol.11
, pp. 1487-1495
-
-
Wellner, U.1
Schubert, J.2
Burk, U.C.3
Schmalhofer, O.4
Zhu, F.5
Sonntag, A.6
Waldvogel, B.7
Vannier, C.8
Darling, D.9
Zur, H.A.10
Brunton, V.G.11
Morton, J.12
Sansom, O.13
Schuler, J.14
Stemmler, M.P.15
Herzberger, C.16
Hopt, U.17
Keck, T.18
Brabletz, S.19
Brabletz, T.20
more..
-
60
-
-
54049084380
-
A double-negative feedback loop between ZEB1-SIP1 and the microRNA-200 family regulates epithelial-mesenchymal transition
-
Bracken C.P., Gregory P.A., Kolesnikoff N., Bert A.G., Wang J., Shannon M.F., Goodall G.J. A double-negative feedback loop between ZEB1-SIP1 and the microRNA-200 family regulates epithelial-mesenchymal transition. Cancer Res. 2008, 68:7846-7854.
-
(2008)
Cancer Res.
, vol.68
, pp. 7846-7854
-
-
Bracken, C.P.1
Gregory, P.A.2
Kolesnikoff, N.3
Bert, A.G.4
Wang, J.5
Shannon, M.F.6
Goodall, G.J.7
-
61
-
-
78751483761
-
MiR-200b targets Ets-1 and is down-regulated by hypoxia to induce angiogenic response of endothelial cells
-
Chan Y.C., Khanna S., Roy S., Sen C.K. miR-200b targets Ets-1 and is down-regulated by hypoxia to induce angiogenic response of endothelial cells. J. Biol. Chem. 2011, 286:2047-2056.
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 2047-2056
-
-
Chan, Y.C.1
Khanna, S.2
Roy, S.3
Sen, C.K.4
-
62
-
-
43049165453
-
Weinberg, The epithelial-mesenchymal transition generates cells with properties of stem cells
-
Mani W., Guo M.J., Liao E.N., Eaton A., Ayyanan A.Y., Zhou M., Brooks F., Reinhard C.C., Zhang M., Shipitsin L.L., Campbell K., Polyak C., Brisken J., Yang R.A. Weinberg, The epithelial-mesenchymal transition generates cells with properties of stem cells. Cell 2008, 133:704-715.
-
(2008)
Cell
, vol.133
, pp. 704-715
-
-
Mani, W.1
Guo, M.J.2
Liao, E.N.3
Eaton, A.4
Ayyanan, A.Y.5
Zhou, M.6
Brooks, F.7
Reinhard, C.C.8
Zhang, M.9
Shipitsin, L.L.10
Campbell, K.11
Polyak, C.12
Brisken, J.13
Yang, R.A.14
-
63
-
-
79955419817
-
Snail and the microRNA-200 family act in oppositioon to regulate epithelial-to-mesencymal transition and germ layer fate restriction in differentiating ESCs
-
Gill J.G., Langer E.L., Lindsley R.C., cai M., Murphy T.L., Kyba M., Murphy K.M. Snail and the microRNA-200 family act in oppositioon to regulate epithelial-to-mesencymal transition and germ layer fate restriction in differentiating ESCs. Stem Cells 2011, 29:764-776.
-
(2011)
Stem Cells
, vol.29
, pp. 764-776
-
-
Gill, J.G.1
Langer, E.L.2
Lindsley, R.C.3
Cai, M.4
Murphy, T.L.5
Kyba, M.6
Murphy, K.M.7
-
64
-
-
34249079154
-
Network motifs: theory and experimental approaches
-
Alon U. Network motifs: theory and experimental approaches. Nat. Rev. Genet. 2007, 8:450-461.
-
(2007)
Nat. Rev. Genet.
, vol.8
, pp. 450-461
-
-
Alon, U.1
-
65
-
-
84855893554
-
Ajuba is required for Rac activation and maintenance of E-cadherin adhesion
-
Nola S., Daigaku R., Smolarczyk K., Carstens M., Martin-Martin B., Longmore G., Bailly M., Braga V.M. Ajuba is required for Rac activation and maintenance of E-cadherin adhesion. J. Cell Biol. 2011, 195:855-871.
-
(2011)
J. Cell Biol.
, vol.195
, pp. 855-871
-
-
Nola, S.1
Daigaku, R.2
Smolarczyk, K.3
Carstens, M.4
Martin-Martin, B.5
Longmore, G.6
Bailly, M.7
Braga, V.M.8
-
66
-
-
43249086048
-
The LIM protein AJUBA recruits protein arginine methyltransferase 5 to mediate SNAIL-dependent transcriptional repression
-
Hou Z., Peng H., Ayyanathan K., Yan K.P., Langer E.M., Longmore G.D., Rauscher F.J. The LIM protein AJUBA recruits protein arginine methyltransferase 5 to mediate SNAIL-dependent transcriptional repression. Mol. Cell. Biol. 2008, 28:3198-3207.
-
(2008)
Mol. Cell. Biol.
, vol.28
, pp. 3198-3207
-
-
Hou, Z.1
Peng, H.2
Ayyanathan, K.3
Yan, K.P.4
Langer, E.M.5
Longmore, G.D.6
Rauscher, F.J.7
-
67
-
-
82755198488
-
Beta-catenin/TCF4 complex induces the epithelial-to-mesenchymal transition (EMT)-activator ZEB1 to regulate tumor invasiveness
-
19294-19209
-
Sánchez-Tillo E., de Barrios O., Siles L., Cuatrecasas M., Castells A., Postigo A. beta-catenin/TCF4 complex induces the epithelial-to-mesenchymal transition (EMT)-activator ZEB1 to regulate tumor invasiveness. Proc. Natl. Acad. Sci. U. S. A. 2011, 108. 19294-19209.
-
(2011)
Proc. Natl. Acad. Sci. U. S. A.
, vol.108
-
-
Sánchez-Tillo, E.1
de Barrios, O.2
Siles, L.3
Cuatrecasas, M.4
Castells, A.5
Postigo, A.6
-
68
-
-
0345599013
-
Autoregulation of E-cadherin expression by cadherin-cadherin interactions: the roles of beta-catenin signaling, Slug, and MAPK
-
Conacci-Sorrell M., Simcha I., Ben-Yedidia T., Blechman J., Savagner P., Ben-Ze'ev A. Autoregulation of E-cadherin expression by cadherin-cadherin interactions: the roles of beta-catenin signaling, Slug, and MAPK. J. Cell Biol. 2003, 163:847-857.
-
(2003)
J. Cell Biol.
, vol.163
, pp. 847-857
-
-
Conacci-Sorrell, M.1
Simcha, I.2
Ben-Yedidia, T.3
Blechman, J.4
Savagner, P.5
Ben-Ze'ev, A.6
-
69
-
-
49149107174
-
Snai1 and Snai2 collaborate on tumor growth and metastasis properties of mouse skin carcinoma cell lines
-
Olmeda D., Montes A., Moreno-Bueno G., Flores J.M., Portillo F., Cano A. Snai1 and Snai2 collaborate on tumor growth and metastasis properties of mouse skin carcinoma cell lines. Oncogene 2008, 27:4690-4701.
-
(2008)
Oncogene
, vol.27
, pp. 4690-4701
-
-
Olmeda, D.1
Montes, A.2
Moreno-Bueno, G.3
Flores, J.M.4
Portillo, F.5
Cano, A.6
-
70
-
-
69449084716
-
Snail2 cooperates with Snail1 in the repression of vitamin D receptor in colon cancer
-
Larriba M.J., Martín-Villar E., García J.M., Pereira F., Peña C., García de Herreros A., Bonilla F., Muñoz A. Snail2 cooperates with Snail1 in the repression of vitamin D receptor in colon cancer. Carcinogenesis 2009, 30:1459-1468.
-
(2009)
Carcinogenesis
, vol.30
, pp. 1459-1468
-
-
Larriba, M.J.1
Martín-Villar, E.2
García, J.M.3
Pereira, F.4
Peña, C.5
García de Herreros, A.6
Bonilla, F.7
Muñoz, A.8
|