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Volumn 287, Issue 13, 2012, Pages 10703-10713

MUC1-C oncoprotein induces TCF7L2 transcription factor activation and promotes cyclin D1 expression in human breast cancer cells

Author keywords

[No Author keywords available]

Indexed keywords

BREAST CANCER; BREAST CANCER CELLS; C-TERMINAL REGIONS; C-TERMINAL-BINDING PROTEINS; CYCLIND1; CYTOPLASMIC DOMAINS; GENE PROMOTER; HUMAN BREAST CANCER CELLS; MEDIATED TRANSCRIPTION; ONCOPROTEINS;

EID: 84858994452     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.323311     Document Type: Article
Times cited : (65)

References (44)
  • 1
    • 33846193290 scopus 로고    scopus 로고
    • The many ways of Wnt in cancer
    • Polakis, P. (2007) The many ways of Wnt in cancer. Curr. Opin. Genet. Dev. 17, 45-51
    • (2007) Curr. Opin. Genet. Dev. , vol.17 , pp. 45-51
    • Polakis, P.1
  • 2
    • 17244376814 scopus 로고    scopus 로고
    • Wnt signalling in stem cells and cancer
    • DOI 10.1038/nature03319
    • Reya, T., and Clevers, H. (2005) Wnt signaling in stem cells and cancer. Nature 434, 843-850 (Pubitemid 40558990)
    • (2005) Nature , vol.434 , Issue.7035 , pp. 843-850
    • Reya, T.1    Clevers, H.2
  • 3
    • 33847367723 scopus 로고    scopus 로고
    • Wnt signaling: Variety at the core
    • Hoppler, S., and Kavanagh, C. L. (2007) Wnt signaling: Variety at the core. J. Cell Sci. 120, 385-393
    • (2007) J. Cell Sci. , vol.120 , pp. 385-393
    • Hoppler, S.1    Kavanagh, C.L.2
  • 4
    • 67650230896 scopus 로고    scopus 로고
    • Wnt/β-catenin signaling: Components, mechanisms, and diseases
    • MacDonald, B. T., Tamai, K., and He, X. (2009) Wnt/β-catenin signaling: Components, mechanisms, and diseases. Dev. Cell 17, 9-26
    • (2009) Dev. Cell , vol.17 , pp. 9-26
    • MacDonald, B.T.1    Tamai, K.2    He, X.3
  • 5
    • 18744400798 scopus 로고    scopus 로고
    • β-catenin directly displaces Groucho/TLE repressors from Tcf/Lef in Wnt-mediated transcription activation
    • DOI 10.1038/nsmb912
    • Daniels, D. L., and Weis, W. I. (2005) β-Catenin directly displaces Groucho/TLE repressors from Tcf/Lef in Wnt-mediated transcription activation. Nat. Struct. Mol. Biol. 12, 364-371 (Pubitemid 43093092)
    • (2005) Nature Structural and Molecular Biology , vol.12 , Issue.4 , pp. 364-371
    • Daniels, D.L.1    Weis, W.I.2
  • 8
    • 77951233751 scopus 로고    scopus 로고
    • Alternative splicing of Tcf7l2 transcripts generates protein variants with differential promoter-binding and transcriptional activation properties at Wnt/β-catenin targets
    • Weise, A., Bruser, K., Elfert, S., Wallmen, B., Wittel, Y., Wöhrle, S., and Hecht, A. (2010) Alternative splicing of Tcf7l2 transcripts generates protein variants with differential promoter-binding and transcriptional activation properties at Wnt/β-catenin targets. Nucleic Acids Res. 38, 1964-1981
    • (2010) Nucleic Acids Res. , vol.38 , pp. 1964-1981
    • Weise, A.1    Bruser, K.2    Elfert, S.3    Wallmen, B.4    Wittel, Y.5    Wöhrle, S.6    Hecht, A.7
  • 10
    • 0037423192 scopus 로고    scopus 로고
    • Identification of a promoter-specific transcriptional activation domain at the C terminus of the Wnt effector protein T-cell factor 4
    • DOI 10.1074/jbc.M210081200
    • Hecht, A., and Stemmler, M. P. (2003) Identification of a promoter-specific transcriptional activation domain at the C terminus of the Wnt effector protein T-cell factor 4. J. Biol. Chem. 278, 3776-3785 (Pubitemid 36801104)
    • (2003) Journal of Biological Chemistry , vol.278 , Issue.6 , pp. 3776-3785
    • Hecht, A.1    Stemmler, M.P.2
  • 11
    • 33646553656 scopus 로고    scopus 로고
    • TCF-4 isoforms absent in TCF-4 mutated MSI-H colorectal cancer cells colocalize with nuclear CtBP and repress TCF-4-mediated transcription
    • DOI 10.1038/sj.onc.1209471, PII 1209471
    • Cuilliere-Dartigues, P., El-Bchiri, J., Krimi, A., Buhard, O., Fontanges, P., Fléjou, J. F., Hamelin, R., and Duval, A. (2006) TCF4 isoforms absent in TCF4 mutated MSI-H colorectal cancer cells colocalize with nuclear CtBP and repress TCF4-mediated transcription. Oncogene 25, 4441-4448 (Pubitemid 44141632)
    • (2006) Oncogene , vol.25 , Issue.32 , pp. 4441-4448
    • Cuilliere-Dartigues, P.1    El-Bchiri, J.2    Krimi, A.3    Buhard, O.4    Fontanges, P.5    Flejou, J.-F.6    Hamelin, R.7    Duval, A.8
  • 12
    • 0038074398 scopus 로고    scopus 로고
    • HMG box transcription factor TCF-4's interaction with CtBP1 controls the expression of the Wnt target Axin2/Conductin in human embryonic kidney cells
    • DOI 10.1093/nar/gkg346
    • Valenta, T., Lukas, J., and Korinek, V. (2003) HMG box transcription factor TCF4 interaction with CtBP1 controls the expression of the Wnt target Axin2/Conductin in human embryonic kidney cells. Nucleic Acids Res. 31, 2369-2380 (Pubitemid 37442105)
    • (2003) Nucleic Acids Research , vol.31 , Issue.9 , pp. 2369-2380
    • Valenta, T.1    Lukas, J.2    Korinek, V.3
  • 13
    • 33750308598 scopus 로고    scopus 로고
    • Role of the C-terminal binding protein PXDLS motif binding cleft in protein interactions and transcriptional repression
    • DOI 10.1128/MCB.00445-06
    • Quinlan, K. G., Verger, A., Kwok, A., Lee, S. H., Perdomo, J., Nardini, M., Bolognesi, M., and Crossley, M. (2006) Role of the C-terminal binding protein PXDLS motif binding cleft in protein interactions and transcriptional repression. Mol. Cell. Biol. 26, 8202-8213 (Pubitemid 44631016)
    • (2006) Molecular and Cellular Biology , vol.26 , Issue.21 , pp. 8202-8213
    • Quinlan, K.G.R.1    Verger, A.2    Kwok, A.3    Lee, S.H.Y.4    Perdomo, J.5    Nardini, M.6    Bolognesi, M.7    Crossley, M.8
  • 14
    • 70450247207 scopus 로고    scopus 로고
    • Mucins in cancer: Function, prognosis, and therapy
    • Kufe, D. (2009) Mucins in cancer: Function, prognosis, and therapy. Nat. Rev. Cancer 9, 874-885
    • (2009) Nat. Rev. Cancer , vol.9 , pp. 874-885
    • Kufe, D.1
  • 15
    • 0021740104 scopus 로고
    • Differential reactivity of a novel monoclonal antibody (DF3) with human malignant versus benign breast tumors
    • Kufe, D., Inghirami, G., Abe, M., Hayes, D., Justi-Wheeler, H., and Schlom, J. (1984) Differential reactivity of a novel monoclonal antibody (DF3) with human malignant versus benign breast tumors. Hybridoma 3, 223-232 (Pubitemid 15184701)
    • (1984) Hybridoma , vol.3 , Issue.3 , pp. 223-232
    • Kufe, D.1    Inghirami, G.2    Abe, M.3
  • 16
    • 0030958706 scopus 로고    scopus 로고
    • Interaction of the DF3/MUC1 breast carcinoma-associated antigen and β- catenin in cell adhesion
    • DOI 10.1074/jbc.272.19.12492
    • Yamamoto, M., Bharti, A., Li, Y., and Kufe, D. (1997) Interaction of the DF3/MUC1 breast carcinoma-associated antigen and β-catenin in cell adhesion. J. Biol. Chem. 272, 12492-12494 (Pubitemid 27203339)
    • (1997) Journal of Biological Chemistry , vol.272 , Issue.19 , pp. 12492-12494
    • Yamamoto, M.1    Bharti, A.2    Li, Y.3    Kufe, D.4
  • 17
    • 79960815298 scopus 로고    scopus 로고
    • MUC1 cytoplasmic domain coactivates Wnt target gene transcription and confers transformation
    • Huang, L., Ren, J., Chen, D., Li, Y., Kharbanda, S., and Kufe, D. (2003) MUC1 cytoplasmic domain coactivates Wnt target gene transcription and confers transformation. Cancer Biol. Ther. 2, 702-706
    • (2003) Cancer Biol. Ther. , vol.2 , pp. 702-706
    • Huang, L.1    Ren, J.2    Chen, D.3    Li, Y.4    Kharbanda, S.5    Kufe, D.6
  • 18
    • 28544448610 scopus 로고    scopus 로고
    • MUC1 oncoprotein blocks glycogen synthase kinase 3β-mediated phosphorylation and degradation of β-catenin
    • DOI 10.1158/0008-5472.CAN-05-2474
    • Huang, L., Chen, D., Liu, D., Yin, L., Kharbanda, S., and Kufe, D. (2005) MUC1 oncoprotein blocks glycogen synthase kinase 3β-mediated phosphorylation and degradation of β-catenin. Cancer Res. 65, 10413-10422 (Pubitemid 41743735)
    • (2005) Cancer Research , vol.65 , Issue.22 , pp. 10413-10422
    • Huang, L.1    Chen, D.2    Liu, D.3    Yin, L.4    Kharbanda, S.5    Kufe, D.6
  • 19
    • 0031723707 scopus 로고    scopus 로고
    • Interaction of glycogen synthase kinase 3β with the DF3/MUC1 carcinoma- associated antigen and β-catenin
    • Li, Y., Bharti, A., Chen, D., Gong, J., and Kufe, D. (1998) Interaction of glycogen synthase kinase 3β with the DF3/MUC1 carcinoma-associated antigen and β-catenin. Mol. Cell. Biol. 18, 7216-7224 (Pubitemid 28533041)
    • (1998) Molecular and Cellular Biology , vol.18 , Issue.12 , pp. 7216-7224
    • Li, Y.1    Bharti, A.2    Chen, D.3    Gong, J.4    Kufe, D.5
  • 20
    • 0037422201 scopus 로고    scopus 로고
    • MUC1 alters β-catenin-dependent tumor formation and promotes cellular invasion
    • DOI 10.1038/sj.onc.1206291
    • Schroeder, J. A., Adriance, M. C., Thompson, M. C., Camenisch, T. D., and Gendler, S. J. (2003) MUC1 alters β-catenin-dependent tumor formation and promotes cellular invasion. Oncogene 22, 1324-1332 (Pubitemid 36384593)
    • (2003) Oncogene , vol.22 , Issue.9 , pp. 1324-1332
    • Schroeder, J.A.1    Adriance, M.C.2    Thompson, M.C.3    Camenisch, T.D.4    Gendler, S.J.5
  • 21
    • 67449127094 scopus 로고    scopus 로고
    • Direct targeting of the mucin 1 oncoprotein blocks survival and tumorigenicity of human breast carcinoma cells
    • Raina, D., Ahmad, R., Joshi, M. D., Yin, L., Wu, Z., Kawano, T., Vasir, B., Avigan, D., Kharbanda, S., and Kufe, D. (2009) Direct targeting of the mucin 1 oncoprotein blocks survival and tumorigenicity of human breast carcinoma cells. Cancer Res. 69, 5133-5141
    • (2009) Cancer Res. , vol.69 , pp. 5133-5141
    • Raina, D.1    Ahmad, R.2    Joshi, M.D.3    Yin, L.4    Wu, Z.5    Kawano, T.6    Vasir, B.7    Avigan, D.8    Kharbanda, S.9    Kufe, D.10
  • 22
    • 34547092962 scopus 로고    scopus 로고
    • Nuclear import of the MUC1-C oncoprotein is mediated by nucleoporin Nup62
    • DOI 10.1074/jbc.M703222200
    • Leng, Y., Cao, C., Ren, J., Huang, L., Chen, D., Ito, M., and Kufe, D. (2007) Nuclear import of the MUC1-C oncoprotein is mediated by nucleoporin Nup62. J. Biol. Chem. 282, 19321-19330 (Pubitemid 47100108)
    • (2007) Journal of Biological Chemistry , vol.282 , Issue.27 , pp. 19321-19330
    • Leng, Y.1    Cao, C.2    Ren, J.3    Huang, L.4    Chen, D.5    Ito, M.6    Kufe, D.7
  • 23
    • 70149111064 scopus 로고    scopus 로고
    • MUC1-C oncoprotein functions as a direct activator of the nuclear factor-κB p65 transcription factor
    • Ahmad, R., Raina, D., Joshi, M. D., Kawano, T., Ren, J., Kharbanda, S., and Kufe, D. (2009) MUC1-C oncoprotein functions as a direct activator of the nuclear factor-κB p65 transcription factor. Cancer Res. 69, 7013-7021
    • (2009) Cancer Res. , vol.69 , pp. 7013-7021
    • Ahmad, R.1    Raina, D.2    Joshi, M.D.3    Kawano, T.4    Ren, J.5    Kharbanda, S.6    Kufe, D.7
  • 25
    • 0037430968 scopus 로고    scopus 로고
    • Association of class I histone deacetylases with transcriptional corepressor CtBP
    • DOI 10.1016/S0014-5793(03)00275-8
    • Subramanian, T., and Chinnadurai, G. (2003) Association of class I histone deacetylases with transcriptional corepressor CtBP. FEBS Lett. 540, 255-258 (Pubitemid 36398067)
    • (2003) FEBS Letters , vol.540 , Issue.1-3 , pp. 255-258
    • Subramanian, T.1    Chinnadurai, G.2
  • 26
    • 0032808135 scopus 로고    scopus 로고
    • XCtBP is a XTcf-3 co-repressor with roles throughout Xenopus development
    • Brannon, M., Brown, J. D., Bates, R., Kimelman, D., and Moon, R. T. (1999) XCtBP is a XTcf-3 co-repressor with roles throughout Xenopus development. Development 126, 3159-3170 (Pubitemid 29378179)
    • (1999) Development , vol.126 , Issue.14 , pp. 3159-3170
    • Brannon, M.1    Brown, J.D.2    Bates, R.3    Kimelman, D.4    Moon, R.T.5
  • 28
    • 73549104289 scopus 로고    scopus 로고
    • KLF4 interacts with β-catenin/TCF4 and blocks p300/CBP recruitment by β-catenin
    • Evans, P. M., Chen, X., Zhang, W., and Liu, C. (2010) KLF4 interacts with β-catenin/TCF4 and blocks p300/CBP recruitment by β-catenin. Mol. Cell. Biol. 30, 372-381
    • (2010) Mol. Cell. Biol. , vol.30 , pp. 372-381
    • Evans, P.M.1    Chen, X.2    Zhang, W.3    Liu, C.4
  • 29
    • 0029131298 scopus 로고
    • Structural basis forDNAbending by the architectural transcription factor LEF-1
    • Love, J. J., Li, X., Case, D. A., Giese, K., Grosschedl, R., and Wright, P. E. (1995) Structural basis forDNAbending by the architectural transcription factor LEF-1. Nature 376, 791-795
    • (1995) Nature , vol.376 , pp. 791-795
    • Love, J.J.1    Li, X.2    Case, D.A.3    Giese, K.4    Grosschedl, R.5    Wright, P.E.6
  • 30
    • 0034660872 scopus 로고    scopus 로고
    • The human T-cell transcription factor-4 gene: Structure, extensive characterization of alternative splicings, and mutational analysis in colorectal cancer cell lines
    • Duval, A., Rolland, S., Tubacher, E., Bui, H., Thomas, G., and Hamelin, R. (2000) The human T-cell transcription factor-4 gene: Structure, extensive characterization of alternative splicings, and mutational analysis in colorectal cancer cell lines. Cancer Res. 60, 3872-3879 (Pubitemid 32204580)
    • (2000) Cancer Research , vol.60 , Issue.14 , pp. 3872-3879
    • Duval, A.1    Rolland, S.2    Tubacher, E.3    Bui, H.4    Thomas, G.5    Hamelin, R.6
  • 31
    • 33845355511 scopus 로고    scopus 로고
    • Diversity of LEF/TCF action in development and disease
    • DOI 10.1038/sj.onc.1210056, PII 1210056
    • Arce, L., Yokoyama, N. N., and Waterman, M. L. (2006) Diversity of LEF/TCF action in development and disease. Oncogene 25, 7492-7504 (Pubitemid 44885748)
    • (2006) Oncogene , vol.25 , Issue.57 , pp. 7492-7504
    • Arce, L.1    Yokoyama, N.N.2    Waterman, M.L.3
  • 32
    • 0029033861 scopus 로고
    • The retinoblastoma protein and cell cycle control
    • Weinberg, R. A. (1995) The retinoblastoma protein and cell cycle control. Cell 81, 323-330
    • (1995) Cell , vol.81 , pp. 323-330
    • Weinberg, R.A.1
  • 34
    • 1642441774 scopus 로고    scopus 로고
    • β-Catenin and Tcfs in Mammary Development and Cancer
    • DOI 10.1023/A:1025944723047, Transcription Factors in Mammary Gland Biology and Neoplasia
    • Hatsell, S., Rowlands, T., Hiremath, M., and Cowin, P. (2003) β-Catenin and Tcfs in mammary development and cancer. J. Mammary Gland. Biol. Neoplasia 8, 145-158 (Pubitemid 38129938)
    • (2003) Journal of Mammary Gland Biology and Neoplasia , vol.8 , Issue.2 , pp. 145-158
    • Hatsell, S.1    Rowlands, T.2    Hiremath, M.3    Cowin, P.4
  • 35
    • 0035963435 scopus 로고    scopus 로고
    • Specific protection against breast cancers by cyclin D1 ablation
    • DOI 10.1038/35082500
    • Yu, Q., Geng, Y., and Sicinski, P. (2001) Specific protection against breast cancers by cyclin D1 ablation. Nature 411, 1017-1021 (Pubitemid 32612319)
    • (2001) Nature , vol.411 , Issue.6841 , pp. 1017-1021
    • Yu, Q.1    Geng, Y.2    Sicinski, P.3
  • 36
    • 30344479175 scopus 로고    scopus 로고
    • Cyclin D1-dependent kinase activity in murine development and mammary tumorigenesis
    • DOI 10.1016/j.ccr.2005.12.019, PII S153561080500396X
    • Landis, M. W., Pawlyk, B. S., Li, T., Sicinski, P., and Hinds, P. W. (2006) Cyclin D1-dependent kinase activity in murine development and mammary tumorigenesis. Cancer Cell 9, 13-22 (Pubitemid 43069507)
    • (2006) Cancer Cell , vol.9 , Issue.1 , pp. 13-22
    • Landis, M.W.1    Pawlyk, B.S.2    Li, T.3    Sicinski, P.4    Hinds, P.W.5
  • 37
    • 73649115686 scopus 로고    scopus 로고
    • Cyclin D1 kinase activity is required for the self-renewal of mammary stem and progenitor cells that are targets of MMTV-ErbB2 tumorigenesis
    • Jeselsohn, R., Brown, N. E., Arendt, L., Klebba, I., Hu, M. G., Kuperwasser, C., and Hinds, P. W. (2010) Cyclin D1 kinase activity is required for the self-renewal of mammary stem and progenitor cells that are targets of MMTV-ErbB2 tumorigenesis. Cancer Cell 17, 65-76
    • (2010) Cancer Cell , vol.17 , pp. 65-76
    • Jeselsohn, R.1    Brown, N.E.2    Arendt, L.3    Klebba, I.4    Hu, M.G.5    Kuperwasser, C.6    Hinds, P.W.7
  • 40
    • 0028331092 scopus 로고
    • Amplification and overexpression of cyclin D1 in breast cancer detected by immunohistochemical staining
    • Gillett, C., Fantl, V., Smith, R., Fisher, C., Bartek, J., Dickson, C., Barnes, D., and Peters, G. (1994) Amplification and overexpression of cyclin D1 in breast cancer detected by immunohistochemical staining. Cancer Res. 54, 1812-1817 (Pubitemid 24116192)
    • (1994) Cancer Research , vol.54 , Issue.7 , pp. 1812-1817
    • Gillett, C.1    Fantl, V.2    Smith, R.3    Fisher, C.4    Bartek, J.5    Dickson, C.6    Barnes, D.7    Peters, G.8
  • 43
    • 39049107744 scopus 로고    scopus 로고
    • GSK-3β regulates cyclin D1 expression: A new target for chemotherapy
    • DOI 10.1016/j.cellsig.2007.10.018, PII S089865680700321X
    • Takahashi-Yanaga, F., and Sasaguri, T. (2008) GSK-3β regulates cyclin D1 expression: A new target for chemotherapy. Cell Signal 20, 581-589 (Pubitemid 351241128)
    • (2008) Cellular Signalling , vol.20 , Issue.4 , pp. 581-589
    • Takahashi-Yanaga, F.1    Sasaguri, T.2


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