-
1
-
-
63049123066
-
Transitions between epithelial and mesenchymal states: Acquisition of malignant and stem cell traits
-
Polyak K, Weinberg RA. Transitions between epithelial and mesenchymal states: Acquisition of malignant and stem cell traits. Nat Rev Cancer 2009; 9: 265-273
-
(2009)
Nat Rev Cancer
, vol.9
, pp. 265-273
-
-
Polyak, K.1
Weinberg, R.A.2
-
2
-
-
70450198396
-
Epithelial-mesenchymal transitions in development and disease
-
Thiery JP, Acloque H, Huang RY, Nieto MA. Epithelial-mesenchymal transitions in development and disease. Cell 2009; 139: 871-890
-
(2009)
Cell
, vol.139
, pp. 871-890
-
-
Thiery, J.P.1
Acloque, H.2
Huang, R.Y.3
Nieto, M.A.4
-
3
-
-
43049165453
-
The epithelialmesenchymal transition generates cells with properties of stem cells
-
Mani SA, Guo W, Liao MJ, Eaton EN, Ayyanan A, Zhou AY, et al. The epithelialmesenchymal transition generates cells with properties of stem cells. Cell 2008; 133: 704-715
-
(2008)
Cell
, vol.133
, pp. 704-715
-
-
Mani, S.A.1
Guo, W.2
Liao, M.J.3
Eaton, E.N.4
Ayyanan, A.5
Zhou, A.Y.6
-
4
-
-
51449085561
-
Generation of breast cancer stem cells through epithelial-mesenchymal transition
-
Morel AP, Lievre M, Thomas C, Hinkal G, Ansieau S, Puisieux A. Generation of breast cancer stem cells through epithelial-mesenchymal transition. PLoS ONe 2008; 3: E2888
-
(2008)
PLoS ONe
, vol.3
-
-
Morel, A.P.1
Lievre, M.2
Thomas, C.3
Hinkal, G.4
Ansieau, S.5
Puisieux, A.6
-
5
-
-
73049110243
-
The EMTactivator ZEB1 promotes tumorigenicity by repressing stemness-inhibiting microRNAs
-
Wellner U, Schubert J, Burk UC, Schmalhofer O, Zhu F, Sonntag A, et al. The EMTactivator ZEB1 promotes tumorigenicity by repressing stemness-inhibiting microRNAs. Nat Cell Biol 2009; 11: 1487-1495
-
(2009)
Nat Cell Biol
, vol.11
, pp. 1487-1495
-
-
Wellner, U.1
Schubert, J.2
Burk, U.C.3
Schmalhofer, O.4
Zhu, F.5
Sonntag, A.6
-
6
-
-
77956230322
-
The ZEB/miR-200 feedback loop-A motor of cellular plasticity in development and cancer
-
Brabletz S, Brabletz T. The ZEB/miR-200 feedback loop-A motor of cellular plasticity in development and cancer? EMBO Rep 2010; 11: 670-677
-
(2010)
EMBO Rep
, vol.11
, pp. 670-677
-
-
Brabletz, S.1
Brabletz, T.2
-
7
-
-
39049160267
-
The transcriptional repressor ZEB1 promotes metastasis and loss of cell polarity in cancer
-
Spaderna S, Schmalhofer O, Wahlbuhl M, Dimmler A, Bauer K, Sultan A, et al. The transcriptional repressor ZEB1 promotes metastasis and loss of cell polarity in cancer. Cancer Res 2008; 68: 537-544
-
(2008)
Cancer Res
, vol.68
, pp. 537-544
-
-
Spaderna, S.1
Schmalhofer, O.2
Wahlbuhl, M.3
Dimmler, A.4
Bauer, K.5
Sultan, A.6
-
8
-
-
33748116186
-
A transient EMT-linked loss of basement membranes indicates metastasis and poor survival in colorectal cancer
-
Spaderna S, Schmalhofer O, Hlubek F, Berx G, Eger A, Merkel S, et al. A transient, EMT-linked loss of basement membranes indicates metastasis and poor survival in colorectal cancer. Gastroenterology 2006; 131: 830-840
-
(2006)
Gastroenterology
, vol.131
, pp. 830-840
-
-
Spaderna, S.1
Schmalhofer, O.2
Hlubek, F.3
Berx, G.4
Eger, A.5
Merkel, S.6
-
9
-
-
35548974844
-
The transcription factor ZEB1 (deltaEF1) promotes tumour cell dedifferentiation by repressing master regulators of epithelial polarity
-
Aigner K, Dampier B, Descovich L, Mikula M, Sultan A, Schreiber M, et al. The transcription factor ZEB1 (deltaEF1) promotes tumour cell dedifferentiation by repressing master regulators of epithelial polarity. Oncogene 2007; 26: 6979-6988
-
(2007)
Oncogene
, vol.26
, pp. 6979-6988
-
-
Aigner, K.1
Dampier, B.2
Descovich, L.3
Mikula, M.4
Sultan, A.5
Schreiber, M.6
-
10
-
-
63049101157
-
The role of the ZEB family of transcription factors in development and disease
-
Vandewalle C, Van Roy F, Berx G. The role of the ZEB family of transcription factors in development and disease. Cell Mol Life Sci 2009; 66: 773-787
-
(2009)
Cell Mol Life Sci
, vol.66
, pp. 773-787
-
-
Vandewalle, C.1
Van Roy, F.2
Berx, G.3
-
11
-
-
44649163918
-
A reciprocal repression between ZEB1 and members of the miR-200 family promotes EMT and invasion in cancer cells
-
Burk U, Schubert J, Wellner U, Schmalhofer O, Vincan E, Spaderna S, et al. A reciprocal repression between ZEB1 and members of the miR-200 family promotes EMT and invasion in cancer cells. EMBO Rep 2008; 9: 582-589
-
(2008)
EMBO Rep
, vol.9
, pp. 582-589
-
-
Burk, U.1
Schubert, J.2
Wellner, U.3
Schmalhofer, O.4
Vincan, E.5
Spaderna, S.6
-
12
-
-
70450247207
-
Mucins in cancer: Function, prognosis and therapy
-
Kufe D. Mucins in cancer: Function, prognosis and therapy. Nat Rev Canc 2009; 9: 874-885
-
(2009)
Nat Rev Canc
, vol.9
, pp. 874-885
-
-
Kufe, D.1
-
13
-
-
84874743726
-
MUC1-C oncoprotein as a target in breast cancer: Activation of signaling pathways and therapeutic approaches
-
Kufe D. MUC1-C oncoprotein as a target in breast cancer: Activation of signaling pathways and therapeutic approaches. Oncogene 2012; 32: 1073-1081
-
(2012)
Oncogene
, vol.32
, pp. 1073-1081
-
-
Kufe, D.1
-
14
-
-
64049093492
-
Erk and pi3k regulate different aspects of the epithelial to mesenchymal transition of mammary tumor cells induced by truncated muc1
-
Horn G, Gaziel A, Wreschner DH, Smorodinsky NI, Ehrlich M. ERK and PI3K regulate different aspects of the epithelial to mesenchymal transition of mammary tumor cells induced by truncated MUC1. Exp Cell Res 2009; 315: 1490-1504
-
(2009)
Exp Cell Res
, vol.315
, pp. 1490-1504
-
-
Horn, G.1
Gaziel, A.2
Wreschner, D.H.3
Smorodinsky, N.I.4
Ehrlich, M.5
-
15
-
-
79953061206
-
MUC1 enhances invasiveness of pancreatic cancer cells by inducing epithelial to mesenchymal transition
-
Roy LD, Sahraei M, Subramani DB, Besmer D, Nath S, Tinder TL, et al. MUC1 enhances invasiveness of pancreatic cancer cells by inducing epithelial to mesenchymal transition. Oncogene 2011; 30: 1449-1459
-
(2011)
Oncogene
, vol.30
, pp. 1449-1459
-
-
Roy, L.D.1
Sahraei, M.2
Subramani, D.B.3
Besmer, D.4
Nath, S.5
Tinder, T.L.6
-
16
-
-
84867047477
-
MUC1-C oncoprotein confers androgen-independent growth of human prostate cancer cells
-
Rajabi H, Ahmad R, Jin C, Joshi M, Guha M, Alam M, et al. MUC1-C oncoprotein confers androgen-independent growth of human prostate cancer cells. Prostate 2012; 72: 1659-1668
-
(2012)
Prostate
, vol.72
, pp. 1659-1668
-
-
Rajabi, H.1
Ahmad, R.2
Jin, C.3
Joshi, M.4
Guha, M.5
Alam, M.6
-
17
-
-
70149111064
-
MUC1-C oncoprotein functions as a direct activator of the NF-kB p65 transcription factor
-
Ahmad R, Raina D, Joshi MD, Kawano T, Kharbanda S, Kufe D. MUC1-C oncoprotein functions as a direct activator of the NF-kB p65 transcription factor. Cancer Res 2009; 69: 7013-7021
-
(2009)
Cancer Res
, vol.69
, pp. 7013-7021
-
-
Ahmad, R.1
Raina, D.2
Joshi, M.D.3
Kawano, T.4
Kharbanda, S.5
Kufe, D.6
-
18
-
-
10744220453
-
Human MUC1 carcinomaassociated protein confers resistance to genotoxic anti-cancer agents
-
Ren J, Agata N, Chen D, Li Y, Yu W-H, Huang L, et al. Human MUC1 carcinomaassociated protein confers resistance to genotoxic anti-cancer agents. Cancer Cell 2004; 5: 163-175
-
(2004)
Cancer Cell
, vol.5
, pp. 163-175
-
-
Ren, J.1
Agata, N.2
Chen, D.3
Li, Y.4
Yu, W.-H.5
Huang, L.6
-
19
-
-
33846828787
-
NF-kappaB represses E-cadherin expression and enhances epithelial to mesenchymal transition of mammary epithelial cells: Potential involvement of ZEB-1 and ZEB-2
-
Chua HL, Bhat-Nakshatri P, Clare SE, Morimiya A, Badve S, Nakshatri H. NF-kappaB represses E-cadherin expression and enhances epithelial to mesenchymal transition of mammary epithelial cells: Potential involvement of ZEB-1 and ZEB-2. Oncogene 2007; 26: 711-724
-
(2007)
Oncogene
, vol.26
, pp. 711-724
-
-
Chua, H.L.1
Bhat-Nakshatri, P.2
Clare, S.E.3
Morimiya, A.4
Badve, S.5
Nakshatri, H.6
-
20
-
-
0035880275
-
An IkappaBalpha inhibitor causes leukemia cell death through a p38 MAP kinasedependent NF-kappaB-independent mechanism
-
Hu X, Janssen WE, Moscinski LC, Bryington M, Dangsupa A, Rezai-Zadeh N, et al. An IkappaBalpha inhibitor causes leukemia cell death through a p38 MAP kinasedependent, NF-kappaB-independent mechanism. Cancer Res 2001; 61: 6290-6296
-
(2001)
Cancer Res
, vol.61
, pp. 6290-6296
-
-
Hu, X.1
Janssen, W.E.2
Moscinski, L.C.3
Bryington, M.4
Dangsupa, A.5
Rezai-Zadeh, N.6
-
21
-
-
84858994452
-
MUC1-C oncoprotein induces TCF7L2 activation and promotes cyclin D1 expression in human breast cancer cells
-
Rajabi H, Ahmad R, Jin C, Kosugi M, Alam M, Joshi M, et al. MUC1-C oncoprotein induces TCF7L2 activation and promotes cyclin D1 expression in human breast cancer cells. J Biol Chem 2012; 287: 10703-10713
-
(2012)
J Biol Chem
, vol.287
, pp. 10703-10713
-
-
Rajabi, H.1
Ahmad, R.2
Jin, C.3
Kosugi, M.4
Alam, M.5
Joshi, M.6
-
22
-
-
34547092962
-
Nuclear import of the MUC1-C oncoprotein is mediated by nucleoporin Nup62
-
Leng Y, Cao C, Ren J, Huang L, Chen D, Ito M, et al. Nuclear import of the MUC1-C oncoprotein is mediated by nucleoporin Nup62. J Biol Chem 2007; 282: 19321-19330
-
(2007)
J Biol Chem
, vol.282
, pp. 19321-19330
-
-
Leng, Y.1
Cao, C.2
Ren, J.3
Huang, L.4
Chen, D.5
Ito, M.6
-
23
-
-
84860279784
-
Targeting cysteine-mediated dimerization of the MUC1-C oncoprotein in human cancer cells
-
Raina D, Ahmad R, Rajabi H, Panchamoorthy G, Kharbanda S, Kufe D. Targeting cysteine-mediated dimerization of the MUC1-C oncoprotein in human cancer cells. Int J Oncol 2012; 40: 1643-1649
-
(2012)
Int J Oncol
, vol.40
, pp. 1643-1649
-
-
Raina, D.1
Ahmad, R.2
Rajabi, H.3
Panchamoorthy, G.4
Kharbanda, S.5
Kufe, D.6
-
24
-
-
47549090432
-
Tgfbeta in cancer
-
Massague J. TGFbeta in Cancer. Cell 2008; 134: 215-230
-
(2008)
Cell
, vol.134
, pp. 215-230
-
-
Massague, J.1
-
25
-
-
33645049305
-
Down-regulation of notch-1 inhibits invasion by inactivation of nuclear factor-kappaB, vascular endothelial growth factor, and matrix metalloproteinase-9 in pancreatic cancer cells
-
Wang Z, Banerjee S, Li Y, Rahman KM, Zhang Y, Sarkar FH. Down-regulation of notch-1 inhibits invasion by inactivation of nuclear factor-kappaB, vascular endothelial growth factor, and matrix metalloproteinase-9 in pancreatic cancer cells. Cancer Res 2006; 66: 2778-2784
-
(2006)
Cancer Res
, vol.66
, pp. 2778-2784
-
-
Wang, Z.1
Banerjee, S.2
Li, Y.3
Rahman, K.M.4
Zhang, Y.5
Sarkar, F.H.6
-
26
-
-
82755198488
-
Betacatenin/ TCF4 complex induces the epithelial-To-mesenchymal transition (EMT)-Activator ZEB1 to regulate tumor invasiveness
-
Sanchez-Tillo E, De Barrios O, Siles L, Cuatrecasas M, Castells A, Postigo A. betacatenin/ TCF4 complex induces the epithelial-To-mesenchymal transition (EMT)-Activator ZEB1 to regulate tumor invasiveness. Proc Natl Acad Sci USA 2011; 108: 19204-19209
-
(2011)
Proc Natl Acad Sci USA
, vol.108
, pp. 19204-19209
-
-
Sanchez-Tillo, E.1
De Barrios, O.2
Siles, L.3
Cuatrecasas, M.4
Castells, A.5
Postigo, A.6
-
27
-
-
28544448610
-
MUC1 oncoprotein blocks GSK3b-mediated phosphorylation and degradation of b-catenin
-
Huang L, Chen D, Liu D, Yin L, Kharbanda S, Kufe D. MUC1 oncoprotein blocks GSK3b-mediated phosphorylation and degradation of b-catenin. Cancer Res 2005; 65: 10413-10422
-
(2005)
Cancer Res
, vol.65
, pp. 10413-10422
-
-
Huang, L.1
Chen, D.2
Liu, D.3
Yin, L.4
Kharbanda, S.5
Kufe, D.6
-
28
-
-
54049084380
-
A double-negative feedback loop between ZEB1-SIP1 and the microRNA-200 family regulates epithelial-mesenchymal transition
-
Bracken CP, Gregory PA, Kolesnikoff N, Bert AG, Wang J, Shannon MF, et al. A double-negative feedback loop between ZEB1-SIP1 and the microRNA-200 family regulates epithelial-mesenchymal transition. Cancer Res 2008; 68: 7846-7854
-
(2008)
Cancer Res
, vol.68
, pp. 7846-7854
-
-
Bracken, C.P.1
Gregory, P.A.2
Kolesnikoff, N.3
Bert, A.G.4
Wang, J.5
Shannon, M.F.6
-
29
-
-
68049114782
-
Downregulation of miRNA-200c links breast cancer stem cells with normal stem cells
-
Shimono Y, Zabala M, Cho RW, Lobo N, Dalerba P, Qian D, et al. Downregulation of miRNA-200c links breast cancer stem cells with normal stem cells. Cell 2009; 138: 592-603
-
(2009)
Cell
, vol.138
, pp. 592-603
-
-
Shimono, Y.1
Zabala, M.2
Cho, R.W.3
Lobo, N.4
Dalerba, P.5
Qian, D.6
-
30
-
-
84870816403
-
Metastatic colonization requires the repression of the epithelial-mesenchymal transition inducer prrx1
-
Ocana OH, Corcoles R, Fabra A, Moreno-Bueno G, Acloque H, Vega S, et al. Metastatic colonization requires the repression of the epithelial-mesenchymal transition inducer prrx1. Cancer Cell 2012; 22: 709-724
-
(2012)
Cancer Cell
, vol.22
, pp. 709-724
-
-
Ocana, O.H.1
Corcoles, R.2
Fabra, A.3
Moreno-Bueno, G.4
Acloque, H.5
Vega, S.6
-
31
-
-
20144388095
-
DeltaEF1 is a transcriptional repressor of E-cadherin and regulates epithelial plasticity in breast cancer cells
-
Eger A, Aigner K, Sonderegger S, Dampier B, Oehler S, Schreiber M, et al. DeltaEF1 is a transcriptional repressor of E-cadherin and regulates epithelial plasticity in breast cancer cells. Oncogene 2005; 24: 2375-2385
-
(2005)
Oncogene
, vol.24
, pp. 2375-2385
-
-
Eger, A.1
Aigner, K.2
Sonderegger, S.3
Dampier, B.4
Oehler, S.5
Schreiber, M.6
-
32
-
-
84863632693
-
Cooperative interaction between the MUC1 oncoprotein and the Rab31 GTPase in human breast cancer cells
-
Jin C, Rajabi H, Pitroda S, Kharbanda A, Li A, Weichselbaum R, et al. Cooperative interaction between the MUC1 oncoprotein and the Rab31 GTPase in human breast cancer cells. PLoS ONE 2012; 7: E39432
-
(2012)
PLoS ONE
, vol.7
-
-
Jin, C.1
Rajabi, H.2
Pitroda, S.3
Kharbanda, A.4
Li, A.5
Weichselbaum, R.6
-
33
-
-
79951904086
-
MUC1-C oncoprotein promotes STAT3 activation in an auto-inductive regulatory loop
-
Ahmad R, Rajabi H, Kosugi M, Joshi M, Alam M, Vasir B, et al. MUC1-C oncoprotein promotes STAT3 activation in an auto-inductive regulatory loop. Science Signaling 2011; 4: Ra9
-
(2011)
Science Signaling
, vol.4
-
-
Ahmad, R.1
Rajabi, H.2
Kosugi, M.3
Joshi, M.4
Alam, M.5
Vasir, B.6
-
34
-
-
24044540381
-
Spatial and temporal recruitment of androgen receptor and its coactivators involves chromosomal looping and polymerase tracking
-
Wang Q, Carroll JS, Brown M. Spatial and temporal recruitment of androgen receptor and its coactivators involves chromosomal looping and polymerase tracking. Mol Cell 2005; 19: 631-642
-
(2005)
Mol Cell
, vol.19
, pp. 631-642
-
-
Wang, Q.1
Carroll, J.S.2
Brown, M.3
-
35
-
-
83455238243
-
A monoclonal antibody against the oncogenic mucin 1 cytoplasmic domain
-
Panchamoorthy G, Rehan H, Kharbanda A, Ahmad R, Kufe D. A monoclonal antibody against the oncogenic mucin 1 cytoplasmic domain. Hybridoma 2011; 30: 531-535
-
(2011)
Hybridoma
, vol.30
, pp. 531-535
-
-
Panchamoorthy, G.1
Rehan, H.2
Kharbanda, A.3
Ahmad, R.4
Kufe, D.5
-
36
-
-
77953178125
-
Mucin 1 oncoprotein expression is suppressed by the miR-125b oncomir
-
Rajabi H, Jin C, Ahmad R, McClary C, Kufe D. Mucin 1 oncoprotein expression is suppressed by the miR-125b oncomir. Genes & Cancer 2010; 1: 62-65
-
(2010)
Genes & Cancer
, vol.1
, pp. 62-65
-
-
Rajabi, H.1
Jin, C.2
Ahmad, R.3
McClary, C.4
Kufe, D.5
-
37
-
-
73649095563
-
IAP regulation of metastasis
-
Mehrotra S, Languino LR, Raskett CM, Mercurio AM, Dohi T, Altieri DC. IAP regulation of metastasis. Cancer Cell 2010; 17: 53-64.
-
(2010)
Cancer Cell
, vol.17
, pp. 53-64
-
-
Mehrotra, S.1
Languino, L.R.2
Raskett, C.M.3
Mercurio, A.M.4
Dohi, T.5
Altieri, D.C.6
|