-
1
-
-
0033895709
-
Wnt signaling and cancer
-
Polakis P. Wnt signaling and cancer. Genes Dev 2000; 14:1837-51.
-
(2000)
Genes Dev
, vol.14
, pp. 1837-1851
-
-
Polakis, P.1
-
2
-
-
0029664368
-
Binding of GSK3β to the APC-β-catenin complex and regulation of complex assembly
-
Rubinfeld B, Albert I, Porfiri E, et al. Binding of GSK3β to the APC-β-catenin complex and regulation of complex assembly. Science 1996;272:1023-6.
-
(1996)
Science
, vol.272
, pp. 1023-1026
-
-
Rubinfeld, B.1
Albert, I.2
Porfiri, E.3
-
3
-
-
0028987249
-
Regulation of intracellular β-catenin levels by the adenomatous polyposis coli (APC) tumor-suppressor protein
-
Munemitsu S, Albert I, Souza B, Rubinfeld B, Polakis P. Regulation of intracellular β-catenin levels by the adenomatous polyposis coli (APC) tumor-suppressor protein. Proc Natl Acad Sci U S A 1995;92:3046-50.
-
(1995)
Proc Natl Acad Sci U S A
, vol.92
, pp. 3046-3050
-
-
Munemitsu, S.1
Albert, I.2
Souza, B.3
Rubinfeld, B.4
Polakis, P.5
-
4
-
-
0031457978
-
The mouse Fused locus encodes Axin, an inhibitor of the Wnt signaling pathway that regulates embryonic axis formation
-
Zeng L, Fagotto F, Zhang T, et al. The mouse Fused locus encodes Axin, an inhibitor of the Wnt signaling pathway that regulates embryonic axis formation. Cell 1997;90:181-92.
-
(1997)
Cell
, vol.90
, pp. 181-192
-
-
Zeng, L.1
Fagotto, F.2
Zhang, T.3
-
5
-
-
0037155691
-
Control of β-catenin phosphorylation/degradation by a dual-kinase mechanism
-
Liu C, Li Y, Semenov M, et al. Control of β-catenin phosphorylation/degradation by a dual-kinase mechanism. Cell 2002;108:837-47.
-
(2002)
Cell
, vol.108
, pp. 837-847
-
-
Liu, C.1
Li, Y.2
Semenov, M.3
-
6
-
-
0030779038
-
Serine phosphorylation-regulated ubiquitination and degradation of β-catenin
-
Orford K, Crockett C, Jensen J, Weissman A, Byers S. Serine phosphorylation-regulated ubiquitination and degradation of β-catenin. J Biol Chem 1997;272:24735-8.
-
(1997)
J Biol Chem
, vol.272
, pp. 24735-24738
-
-
Orford, K.1
Crockett, C.2
Jensen, J.3
Weissman, A.4
Byers, S.5
-
8
-
-
0030949463
-
Activation of β-catenin-Tcf signaling in colon cancer by mutations in β-catenin or APC
-
Morin PJ, Sparks AB, Korinek V, et al. Activation of β-catenin-Tcf signaling in colon cancer by mutations in β-catenin or APC. Science 1997;275:1787-90.
-
(1997)
Science
, vol.275
, pp. 1787-1790
-
-
Morin, P.J.1
Sparks, A.B.2
Korinek, V.3
-
9
-
-
0030958706
-
Interaction of the DF3/MUC1 breast carcinoma-associated antigen and β-catenin in cell adhesion
-
Yamamoto M, Bharti A, Li Y, Kufe D. Interaction of the DF3/MUC1 breast carcinoma-associated antigen and β-catenin in cell adhesion. J Biol Chem 1997;272:12492-4.
-
(1997)
J Biol Chem
, vol.272
, pp. 12492-12494
-
-
Yamamoto, M.1
Bharti, A.2
Li, Y.3
Kufe, D.4
-
10
-
-
0021740104
-
Differential reactivity of a novel monoclonal antibody (DF3) with human malignant versus benign breast tumors
-
Kufe D, Inghirami G, Abe M, et al. Differential reactivity of a novel monoclonal antibody (DF3) with human malignant versus benign breast tumors. Hybridoma 1984;3:223-32.
-
(1984)
Hybridoma
, vol.3
, pp. 223-232
-
-
Kufe, D.1
Inghirami, G.2
Abe, M.3
-
11
-
-
0038012891
-
Patterns of MUC1 tissue expression defined by an anti-MUC1 cytoplasmic tail monoclonal antibody in breast cancer
-
Croce MV, Isla-Larrain MT, Rua CE, et al. Patterns of MUC1 tissue expression defined by an anti-MUC1 cytoplasmic tail monoclonal antibody in breast cancer. J Histochem Cytochem 2003;51:781-8.
-
(2003)
J Histochem Cytochem
, vol.51
, pp. 781-788
-
-
Croce, M.V.1
Isla-Larrain, M.T.2
Rua, C.E.3
-
12
-
-
0026733662
-
Cell-associated episialin is a complex containing two proteins derived from a common precursor
-
Ligtenberg MJ, Kruijshaar L, Buijs F, et al. Cell-associated episialin is a complex containing two proteins derived from a common precursor. J Biol Chem 1992;267:6171-7.
-
(1992)
J Biol Chem
, vol.267
, pp. 6171-6177
-
-
Ligtenberg, M.J.1
Kruijshaar, L.2
Buijs, F.3
-
13
-
-
0024121580
-
Isolation and sequencing of a cDNA coding for the human DF3 breast carcinoma-associated antigen
-
Siddiqui J, Abe M, Hayes D, et al. Isolation and sequencing of a cDNA coding for the human DF3 breast carcinoma-associated antigen. Proc Natl Acad Sci U S A 1988;85:2320-3.
-
(1988)
Proc Natl Acad Sci U S A
, vol.85
, pp. 2320-2323
-
-
Siddiqui, J.1
Abe, M.2
Hayes, D.3
-
14
-
-
0024834409
-
DF3 tumor-associated antigen gene is located in a region on chromosome 1q frequently altered in primary human breast cancer
-
Merlo G, Siddiqui J, Cropp C, et al. DF3 tumor-associated antigen gene is located in a region on chromosome 1q frequently altered in primary human breast cancer. Cancer Res 1989;49:6966-71.
-
(1989)
Cancer Res
, vol.49
, pp. 6966-6971
-
-
Merlo, G.1
Siddiqui, J.2
Cropp, C.3
-
15
-
-
11144240877
-
DF3/MUC1 signaling in multiple myeloma cells is regulated by interleukin-7
-
Li Y, Chen W, Ren J, et al. DF3/MUC1 signaling in multiple myeloma cells is regulated by interleukin-7. Cancer Biol Ther 2003;2:187-93.
-
(2003)
Cancer Biol Ther
, vol.2
, pp. 187-193
-
-
Li, Y.1
Chen, W.2
Ren, J.3
-
16
-
-
0041828907
-
Heregulin targets γ-catenin to the nucleolus by a mechanism dependent on the DF3/MUC1 protein
-
Li Y, Yu W-H, Ren J, et al. Heregulin targets γ-catenin to the nucleolus by a mechanism dependent on the DF3/MUC1 protein. Mol Cancer Res 2003;1:765-75.
-
(2003)
Mol Cancer Res
, vol.1
, pp. 765-775
-
-
Li, Y.1
Yu, W.-H.2
Ren, J.3
-
17
-
-
0041850346
-
Human DF3/MUC1 carcinoma-associated protein functions as an oncogene
-
Li Y, Liu D, Chen D, Kharbanda S, Kufe D. Human DF3/MUC1 carcinoma-associated protein functions as an oncogene. Oncogene 2003;22:6107-10.
-
(2003)
Oncogene
, vol.22
, pp. 6107-6110
-
-
Li, Y.1
Liu, D.2
Chen, D.3
Kharbanda, S.4
Kufe, D.5
-
18
-
-
0141733054
-
Nuclear association of the cytoplasmic tail of MUC1 and β-catenin
-
Wen Y, Caffrey T, Wheelock M, Johnson K, Hollingsworth M. Nuclear association of the cytoplasmic tail of MUC1 and β-catenin. J Biol Chem 2003;278:38029-39.
-
(2003)
J Biol Chem
, vol.278
, pp. 38029-38039
-
-
Wen, Y.1
Caffrey, T.2
Wheelock, M.3
Johnson, K.4
Hollingsworth, M.5
-
19
-
-
10744220453
-
Human MUC1 carcinoma-associated protein confers resistance to genotoxic anti-cancer agents
-
Ren J, Agata N, Chen D, et al. Human MUC1 carcinoma-associated protein confers resistance to genotoxic anti-cancer agents. Cancer Cell 2004;5:163-75.
-
(2004)
Cancer Cell
, vol.5
, pp. 163-175
-
-
Ren, J.1
Agata, N.2
Chen, D.3
-
20
-
-
79960815298
-
MUC1 cytoplasmic domain coactivates Wnt target gene transcription and confers transformation
-
Huang L, Ren J, Chen D, et al. MUC1 cytoplasmic domain coactivates Wnt target gene transcription and confers transformation. Cancer Biol Ther 2003;2:702-6.
-
(2003)
Cancer Biol Ther
, vol.2
, pp. 702-706
-
-
Huang, L.1
Ren, J.2
Chen, D.3
-
21
-
-
2442693937
-
The MUC1 oncoprotein activates the anti-apoptotic PI3K/Akt and Bcl-xL pathways in rat 3Y1 fibroblasts
-
Raina D, Kharbanda S, Kufe D. The MUC1 oncoprotein activates the anti-apoptotic PI3K/Akt and Bcl-xL pathways in rat 3Y1 fibroblasts. J Biol Chem 2004;279:20607-12.
-
(2004)
J Biol Chem
, vol.279
, pp. 20607-20612
-
-
Raina, D.1
Kharbanda, S.2
Kufe, D.3
-
22
-
-
7944230166
-
MUC1 oncoprotein activates the FOXO3a transcription factor in a survival response to oxidative stress
-
Yin L, Huang L, Kufe D. MUC1 oncoprotein activates the FOXO3a transcription factor in a survival response to oxidative stress. J Biol Chem 2004;279:45721-7.
-
(2004)
J Biol Chem
, vol.279
, pp. 45721-45727
-
-
Yin, L.1
Huang, L.2
Kufe, D.3
-
23
-
-
13844262819
-
Human MUC1 oncoprotein regulates p53-responsive gene transcription in the genotoxic stress response
-
Wei X, Xu H, Kufe D. Human MUC1 oncoprotein regulates p53-responsive gene transcription in the genotoxic stress response. Cancer Cell 2005;7:167-78.
-
(2005)
Cancer Cell
, vol.7
, pp. 167-178
-
-
Wei, X.1
Xu, H.2
Kufe, D.3
-
24
-
-
0031723707
-
Interaction of glycogen synthase kinase 3β with the DF3/MUC1 carcinoma-associated antigen and β-catenin
-
Li Y, Bharti A, Chen D, Gong J, Kufe D. Interaction of glycogen synthase kinase 3β with the DF3/MUC1 carcinoma-associated antigen and β-catenin. Mol Cell Biol 1998;18:7216-24.
-
(1998)
Mol Cell Biol
, vol.18
, pp. 7216-7224
-
-
Li, Y.1
Bharti, A.2
Chen, D.3
Gong, J.4
Kufe, D.5
-
25
-
-
0035929643
-
The EGF receptor regulates interaction of the human DF3/MUC1 carcinoma antigen with c-Src and β-catenin
-
Li Y, Ren J, Yu W-H, et al. The EGF receptor regulates interaction of the human DF3/MUC1 carcinoma antigen with c-Src and β-catenin. J Biol Chem 2001;276:35239-42.
-
(2001)
J Biol Chem
, vol.276
, pp. 35239-35242
-
-
Li, Y.1
Ren, J.2
Yu, W.-H.3
-
26
-
-
0035794215
-
The c-Src tyrosine kinase regulates signaling of the human DF3/MUC1 carcinoma-associated antigen with GSK3β and β-catenin
-
Li Y, Kuwahara H, Ren J, Wen G, Kufe D. The c-Src tyrosine kinase regulates signaling of the human DF3/MUC1 carcinoma-associated antigen with GSK3β and β-catenin. J Biol Chem 2001;276:6061-4.
-
(2001)
J Biol Chem
, vol.276
, pp. 6061-6064
-
-
Li, Y.1
Kuwahara, H.2
Ren, J.3
Wen, G.4
Kufe, D.5
-
27
-
-
0842288993
-
Interaction of human MUC1 and β-catenin is regulated by Lck and ZAP-70 in activated Jurkat T cells
-
Li Q, Ren J, Kufe D. Interaction of human MUC1 and β-catenin is regulated by Lck and ZAP-70 in activated Jurkat T cells. Biochem Biophys Res Commun 2004;315:471-6.
-
(2004)
Biochem Biophys Res Commun
, vol.315
, pp. 471-476
-
-
Li, Q.1
Ren, J.2
Kufe, D.3
-
28
-
-
0034678610
-
The p300/CBP acetyltransferases function as transcriptional coactivators of β-catenin in vertebrates
-
Hecht A, Vleminckx K, Stemmler MP, van Roy F, Kemler R. The p300/CBP acetyltransferases function as transcriptional coactivators of β-catenin in vertebrates. EMBO J 2000;19:1839-50.
-
(2000)
EMBO J
, vol.19
, pp. 1839-1850
-
-
Hecht, A.1
Vleminckx, K.2
Stemmler, M.P.3
Van Roy, F.4
Kemler, R.5
-
29
-
-
0036166297
-
Wnt signals are transmitted through N-terminally dephosphorylated β-catenin
-
Staal FJ, Noort Mv M, Strous GJ, Clevers HC. Wnt signals are transmitted through N-terminally dephosphorylated β-catenin. EMBO Rep 2002;3:63-8.
-
(2002)
EMBO Rep
, vol.3
, pp. 63-68
-
-
Staal, F.J.1
Noort, Mv.M.2
Strous, G.J.3
Clevers, H.C.4
-
30
-
-
0033602227
-
The F-box protein β-TrCP associates with phosphorylated β-catenin and regulates its activity in the cell
-
Hart M, Concordet JP, Lassot I, et al. The F-box protein β-TrCP associates with phosphorylated β-catenin and regulates its activity in the cell. Curr Biol 1999;9:207-10.
-
(1999)
Curr Biol
, vol.9
, pp. 207-210
-
-
Hart, M.1
Concordet, J.P.2
Lassot, I.3
-
31
-
-
0033068154
-
The SCFβ-TRCP-ubiquitin ligase complex associates specifically with phosphorylated destruction motifs in IκBα and β-catenin and stimulates IκBα ubiquitination in vitro
-
Winston JT, Strack P, Beer-Romero P, et al. The SCFβ-TRCP-ubiquitin ligase complex associates specifically with phosphorylated destruction motifs in IκBα and β-catenin and stimulates IκBα ubiquitination in vitro. Genes Dev 1999;13:270-83.
-
(1999)
Genes Dev
, vol.13
, pp. 270-283
-
-
Winston, J.T.1
Strack, P.2
Beer-Romero, P.3
-
32
-
-
0030900696
-
Stabilization of β-catenin by genetic defects in melanoma cell lines
-
Rubinfeld B, Robbins P, El-Gamil M, et al. Stabilization of β-catenin by genetic defects in melanoma cell lines. Science 1997;275:1790-2.
-
(1997)
Science
, vol.275
, pp. 1790-1792
-
-
Rubinfeld, B.1
Robbins, P.2
El-Gamil, M.3
-
33
-
-
0034644526
-
Linking colorectal cancer to Wnt signaling
-
Bienz M, Clevers H. Linking colorectal cancer to Wnt signaling. Cell 2000;103:311-20.
-
(2000)
Cell
, vol.103
, pp. 311-320
-
-
Bienz, M.1
Clevers, H.2
-
34
-
-
0034636153
-
β-Catenin, a novel prognostic marker for breast cancer: Its roles in cyclin D1 expression and cancer progression
-
Lin SY, Xia W, Wang JC, et al. β-Catenin, a novel prognostic marker for breast cancer: its roles in cyclin D1 expression and cancer progression. Proc Natl Acad Sci U S A 2000;97:4262-6.
-
(2000)
Proc Natl Acad Sci U S A
, vol.97
, pp. 4262-4266
-
-
Lin, S.Y.1
Xia, W.2
Wang, J.C.3
-
35
-
-
0034840950
-
Pin1 regulates turnover and subcellular localization of β-catenin by inhibiting its interaction with APC
-
Ryo A, Nakamura M, Wulf G, Liou YC, Lu KP. Pin1 regulates turnover and subcellular localization of β-catenin by inhibiting its interaction with APC. Nat Cell Biol 2001;3:793-801.
-
(2001)
Nat Cell Biol
, vol.3
, pp. 793-801
-
-
Ryo, A.1
Nakamura, M.2
Wulf, G.3
Liou, Y.C.4
Lu, K.P.5
-
36
-
-
11144355980
-
MUC1 and nuclear β-catenin are coexpressed at the invasion front of colorectal carcinomas and are both correlated with tumor prognosis
-
Baldus SE, Monig SP, Huxel S, et al. MUC1 and nuclear β-catenin are coexpressed at the invasion front of colorectal carcinomas and are both correlated with tumor prognosis. Clin Cancer Res 2004;10:2790-6.
-
(2004)
Clin Cancer Res
, vol.10
, pp. 2790-2796
-
-
Baldus, S.E.1
Monig, S.P.2
Huxel, S.3
-
37
-
-
0027756014
-
Association of the APC tumor suppressor protein with catenins
-
Su L-K, Vogelstein B, Kanzler KW. Association of the APC tumor suppressor protein with catenins. Science 1993;262:1734-7.
-
(1993)
Science
, vol.262
, pp. 1734-1737
-
-
Su, L.-K.1
Vogelstein, B.2
Kanzler, K.W.3
-
38
-
-
0027738023
-
Association of the APC gene product with β-catenin
-
Rubinfeld B, Souza B, Albert I, et al. Association of the APC gene product with β-catenin. Science 1993;262:1731-4.
-
(1993)
Science
, vol.262
, pp. 1731-1734
-
-
Rubinfeld, B.1
Souza, B.2
Albert, I.3
-
39
-
-
0028170977
-
β-Catenin mediates the interaction of the cadherin-catenin complex with epidermal growth factor receptor
-
Hoschuetzky H, Aberle H, Kemler R. β-Catenin mediates the interaction of the cadherin-catenin complex with epidermal growth factor receptor. J Cell Biol 1994;127:1375-80.
-
(1994)
J Cell Biol
, vol.127
, pp. 1375-1380
-
-
Hoschuetzky, H.1
Aberle, H.2
Kemler, R.3
-
40
-
-
0033635606
-
Crystal structure of a β-catenin/Tcf complex
-
Graham TA, Weaver C, Mao F, Kimelman D, Xu W. Crystal structure of a β-catenin/Tcf complex. Cell 2000; 103:885-96.
-
(2000)
Cell
, vol.103
, pp. 885-896
-
-
Graham, T.A.1
Weaver, C.2
Mao, F.3
Kimelman, D.4
Xu, W.5
-
41
-
-
0030800831
-
Three-dimensional structure of the armadillo repeat region of β-catenin
-
Huber AH, Nelson WJ, Weis WI. Three-dimensional structure of the armadillo repeat region of β-catenin. Cell 1997;90:871-82.
-
(1997)
Cell
, vol.90
, pp. 871-882
-
-
Huber, A.H.1
Nelson, W.J.2
Weis, W.I.3
-
42
-
-
0028572556
-
E-cadherin and APC compete for the interaction with β-catenin and the cytoskeleton
-
Hulsken J, Birchmeier W, Behrens J. E-cadherin and APC compete for the interaction with β-catenin and the cytoskeleton. J Cell Biol 1994;127:2061-9.
-
(1994)
J Cell Biol
, vol.127
, pp. 2061-2069
-
-
Hulsken, J.1
Birchmeier, W.2
Behrens, J.3
-
43
-
-
0344442773
-
Crystal structure of a β-catenin/axin complex suggests a mechanism for the β-catenin destruction complex
-
Xing Y, Clements WK, Kimelman D, Xu W. Crystal structure of a β-catenin/axin complex suggests a mechanism for the β-catenin destruction complex. Genes Dev 2003;17:2753-64.
-
(2003)
Genes Dev
, vol.17
, pp. 2753-2764
-
-
Xing, Y.1
Clements, W.K.2
Kimelman, D.3
Xu, W.4
-
44
-
-
0032562603
-
Functional interaction of an axin homolog, conductin, with β-catenin, APC, and GSK3β
-
Behrens J, Jerchow BA, Wurtele M, et al. Functional interaction of an axin homolog, conductin, with β-catenin, APC, and GSK3β. Science 1998;280:596-9.
-
(1998)
Science
, vol.280
, pp. 596-599
-
-
Behrens, J.1
Jerchow, B.A.2
Wurtele, M.3
-
45
-
-
0035015867
-
β-Catenin and its multiple partners: Promiscuity explained
-
Shapiro L. β-Catenin and its multiple partners: promiscuity explained. Nat Struct Biol 2001;8:484-7.
-
(2001)
Nat Struct Biol
, vol.8
, pp. 484-487
-
-
Shapiro, L.1
-
46
-
-
0028953279
-
The APC protein and E-cadherin form similar but independent complexes with α-catenin, β-catenin, and plakoglobin
-
Rubinfeld B, Souza B, Albert I, Munemitsu S, Polakis P. The APC protein and E-cadherin form similar but independent complexes with α-catenin, β-catenin, and plakoglobin. J Biol Chem 1995;270:5549-55.
-
(1995)
J Biol Chem
, vol.270
, pp. 5549-5555
-
-
Rubinfeld, B.1
Souza, B.2
Albert, I.3
Munemitsu, S.4
Polakis, P.5
-
47
-
-
0033574527
-
Phosphorylation of axin, a Wnt signal negative regulator, by glycogen synthase kinase-3β regulates its stability
-
Yamamoto H, Kishida S, Kishida M, et al. Phosphorylation of axin, a Wnt signal negative regulator, by glycogen synthase kinase-3β regulates its stability. J Biol Chem 1999;274:10681-4.
-
(1999)
J Biol Chem
, vol.274
, pp. 10681-10684
-
-
Yamamoto, H.1
Kishida, S.2
Kishida, M.3
-
48
-
-
0033565533
-
Wnt-induced dephosphorylation of axin releases β-catenin from the axin complex
-
Willert K, Shibamoto S, Nusse R. Wnt-induced dephosphorylation of axin releases β-catenin from the axin complex. Genes Dev 1999;13:1768-73.
-
(1999)
Genes Dev
, vol.13
, pp. 1768-1773
-
-
Willert, K.1
Shibamoto, S.2
Nusse, R.3
-
49
-
-
0027968669
-
Expression of MUC-1 on myeloma cells and induction of HLA-unrestricted CTL against MUC1 from a multiple myeloma patient
-
Takahashi T, Makiguchi Y, Hinoda Y, et al. Expression of MUC-1 on myeloma cells and induction of HLA-unrestricted CTL against MUC1 from a multiple myeloma patient. J Immunol 1994;153:2102-9.
-
(1994)
J Immunol
, vol.153
, pp. 2102-2109
-
-
Takahashi, T.1
Makiguchi, Y.2
Hinoda, Y.3
-
50
-
-
4143099166
-
MUC1 overexpression results in mammary gland tumorigenesis and prolonged alveolar differentiation
-
Schroeder JA, Masri AA, Adriance MC, et al. MUC1 overexpression results in mammary gland tumorigenesis and prolonged alveolar differentiation. Oncogene 2004;23:5739-47.
-
(2004)
Oncogene
, vol.23
, pp. 5739-5747
-
-
Schroeder, J.A.1
Masri, A.A.2
Adriance, M.C.3
|