The reactive tumor microenvironment: MUC1 signaling directly reprograms transcription of CTGF

Oncogene

Volumn 29, Issue 42, 2010, Pages 5667-5677

  Behrens, M E ^a,b   Grandgenett, P M ^a   Bailey, J M ^a   Singh, P K ^a,b   Yi, C H ^a   Yu, F ^a   Hollingsworth, M A ^a,b  

^a UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

^b UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

Author keywords

CTGF; MUC1; pancreatic cancer; signal transduction; transcriptional activation

Indexed keywords

BETA CATENIN; CONNECTIVE TISSUE GROWTH FACTOR; MUCIN 1; TRANSCRIPTION FACTOR; CTGF PROTEIN, HUMAN; MUC1 PROTEIN, HUMAN;

ANGIOGENESIS; ARTICLE; CANCER GROWTH; CANCER INVASION; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; DNA MICROARRAY; EXTRACELLULAR MATRIX; GENE CONTROL; GENE EXPRESSION; GENE TARGETING; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; METASTASIS; MOLECULAR MECHANICS; MUTANT; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; BIOSYNTHESIS; GENE EXPRESSION REGULATION; GENETICS; IMMUNOBLOTTING; METABOLISM; PANCREAS TUMOR; PHOSPHORYLATION; PROMOTER REGION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; TUMOR CELL LINE;

CELL LINE, TUMOR; CHROMATIN IMMUNOPRECIPITATION; CONNECTIVE TISSUE GROWTH FACTOR; EXTRACELLULAR MATRIX; GENE EXPRESSION; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; IMMUNOBLOTTING; MUCIN-1; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PANCREATIC NEOPLASMS; PHOSPHORYLATION; PROMOTER REGIONS, GENETIC; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; TRANSCRIPTION, GENETIC;

EID: 77958494724     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/onc.2010.327     Document Type: Article

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