MUC1 protein expression in tumor cells regulates transcription of proinflammatory cytokines by forming a complex with nuclear factor-κB p65 and binding to cytokine promoters: Importance of extracellular domain

Journal of Biological Chemistry

Volumn 286, Issue 49, 2011, Pages 42248-42256

  Cascio, Sandra ^a,b   Zhang, Lixin ^a   Finn, Olivera J ^a  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^b Fondazione RiMED   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

CANCER CELLS; CANCER DEVELOPMENT; CDNA ENCODING; CELL-CELL COMMUNICATIONS; CHEMOTACTIC ACTIVITY; CYTOKINES; EPITHELIAL CELLS; EXPRESSION LEVELS; EXTRACELLULAR DOMAINS; HUMAN ADENOCARCINOMA; HUMAN BREAST CANCER CELLS; INNATE IMMUNE SYSTEMS; ISOFORMS; NUCLEAR FACTORS; OVER-EXPRESSION; PROINFLAMMATORY CYTOKINES; PROMOTER REGION; PROTEIN EXPRESSIONS; REAL-TIME PCR; TANDEM REPEATS; TRANSCRIPTIONAL REGULATION; TRANSMEMBRANE GLYCOPROTEINS; TUMOR CELLS; VARIABLE NUMBER;

DISEASES; MOLECULAR BIOLOGY; POLYMERASE CHAIN REACTION; TUMORS;

CELLS;

COMPLEMENTARY DNA; CYTOKINE; HYBRID PROTEIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN SYNAPTOTAGMIN I; INTERLEUKIN 2; MUCIN 1; SYNAPTOTAGMIN I; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BREAST CANCER; CANCER CELL; CHROMATIN IMMUNOPRECIPITATION; COMPLEX FORMATION; CONTROLLED STUDY; EXTRACELLULAR SPACE; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FAMILY; REAL TIME POLYMERASE CHAIN REACTION; TRANSCRIPTION REGULATION; UPREGULATION; VARIABLE NUMBER OF TANDEM REPEAT;

ADENOCARCINOMA; ANIMALS; BREAST NEOPLASMS; CELL LINE, TUMOR; CYTOKINES; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; INFLAMMATION; INTERLEUKIN-6; MICE; MICE, INBRED C57BL; MUCIN-1; PROTEIN BINDING; TRANSCRIPTION FACTOR RELA; TUMOR NECROSIS FACTOR-ALPHA;

EID: 82755195700     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.297630     Document Type: Article

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