-
1
-
-
70450247207
-
Mucins in cancer: Function, prognosis and therapy
-
Kufe D: Mucins in cancer: function, prognosis and therapy. Nat Rev Cancer 9: 874-885, 2009.
-
(2009)
Nat Rev Cancer
, vol.9
, pp. 874-885
-
-
Kufe, D.1
-
2
-
-
0021740104
-
Differential reactivity of a novel monoclonal antibody (DF3) with human malignant versus benign breast tumors
-
Kufe D, Inghirami G, Abe M, Hayes D, Justi-Wheeler H and Schlom J: Differential reactivity of a novel monoclonal antibody (DF3) with human malignant versus benign breast tumors. Hybridoma 3: 223-232, 1984. (Pubitemid 15184701)
-
(1984)
Hybridoma
, vol.3
, Issue.3
, pp. 223-232
-
-
Kufe, D.1
Inghirami, G.2
Abe, M.3
-
3
-
-
34748902247
-
The MUC1 and Galectin-3 Oncoproteins Function in a MicroRNA-Dependent Regulatory Loop
-
DOI 10.1016/j.molcel.2007.07.031, PII S1097276507005631
-
Ramasamy S, Duraisamy S, Barbashov S, Kawano T, Kharbanda S and Kufe D: The MUC1 and galectin-3 oncoproteins function in a microRNA-dependent regulatory loop. Mol Cell 27: 992-1004, 2007. (Pubitemid 47488189)
-
(2007)
Molecular Cell
, vol.27
, Issue.6
, pp. 992-1004
-
-
Ramasamy, S.1
Duraisamy, S.2
Barbashov, S.3
Kawano, T.4
Kharbanda, S.5
Kufe, D.6
-
4
-
-
0035929643
-
The EGF receptor regulates interaction of the human DF3/MUC1 carcinoma antigen with c-src and β-catenin
-
Li Y, Ren J, Yu W, et al: The EGF receptor regulates interaction of the human DF3/MUC1 carcinoma antigen with c-src and β-catenin. J Biol Chem 276: 35239-35242, 2001.
-
(2001)
J Biol Chem
, vol.276
, pp. 35239-35242
-
-
Li, Y.1
Ren, J.2
Yu, W.3
-
5
-
-
0041850346
-
Human DF3/MUC1 carcinoma-associated protein functions as an oncogene
-
DOI 10.1038/sj.onc.1206732
-
Li Y, Liu D, Chen D, Kharbanda S and Kufe D: Human DF3/MUC1 carcinoma-associated protein functions as an oncogene. Oncogene 22: 6107-6110, 2003. (Pubitemid 37175889)
-
(2003)
Oncogene
, vol.22
, Issue.38
, pp. 6107-6110
-
-
Li, Y.1
Liu, D.2
Chen, D.3
Kharbanda, S.4
Kufe, D.5
-
6
-
-
28544448610
-
MUC1 oncoprotein blocks glycogen synthase kinase 3β-mediated phosphorylation and degradation of β-catenin
-
DOI 10.1158/0008-5472.CAN-05-2474
-
Huang L, Chen D, Liu D, Yin L, Kharbanda S and Kufe D: MUC1 oncoprotein blocks GSK3β-mediated phosphorylation and degradation of β-catenin. Cancer Res 65: 10413-10422, 2005. (Pubitemid 41743735)
-
(2005)
Cancer Research
, vol.65
, Issue.22
, pp. 10413-10422
-
-
Huang, L.1
Chen, D.2
Liu, D.3
Yin, L.4
Kharbanda, S.5
Kufe, D.6
-
7
-
-
0030958706
-
Interaction of the DF3/MUC1 breast carcinoma-associated antigen and β- catenin in cell adhesion
-
DOI 10.1074/jbc.272.19.12492
-
Yamamoto M, Bharti A, Li Y and Kufe D: Interaction of the DF3/MUC1 breast carcinoma-associated antigen and β-catenin in cell adhesion. J Biol Chem 272: 12492-12494, 1997. (Pubitemid 27203339)
-
(1997)
Journal of Biological Chemistry
, vol.272
, Issue.19
, pp. 12492-12494
-
-
Yamamoto, M.1
Bharti, A.2
Li, Y.3
Kufe, D.4
-
8
-
-
13844262819
-
Human MUC1 oncoprotein regulates p53-responsive gene transcription in the genotoxic stress response
-
DOI 10.1016/j.ccr.2005.01.008
-
Wei X, Xu H and Kufe D: Human MUC1 oncoprotein regulates p53-responsive gene transcription in the genotoxic stress response. Cancer Cell 7: 167-178, 2005. (Pubitemid 40248342)
-
(2005)
Cancer Cell
, vol.7
, Issue.2
, pp. 167-178
-
-
Wei, X.1
Xu, H.2
Kufe, D.3
-
9
-
-
70149111064
-
MUC1-C oncoprotein functions as a direct activator of the NF-κB p65 transcription factor
-
Ahmad R, Raina D, Joshi MD, Kawano T, Kharbanda S and Kufe D: MUC1-C oncoprotein functions as a direct activator of the NF-κB p65 transcription factor. Cancer Res 69: 7013-7021, 2009.
-
(2009)
Cancer Res
, vol.69
, pp. 7013-7021
-
-
Ahmad, R.1
Raina, D.2
Joshi, M.D.3
Kawano, T.4
Kharbanda, S.5
Kufe, D.6
-
10
-
-
79951904086
-
MUC1-C oncoprotein promotes STAT3 activation in an auto-inductive regulatory loop
-
Ahmad R, Rajabi H, Kosugi M, et al: MUC1-C oncoprotein promotes STAT3 activation in an auto-inductive regulatory loop. Sci Signal 4: ra9, 2011.
-
(2011)
Sci Signal
, vol.4
-
-
Ahmad, R.1
Rajabi, H.2
Kosugi, M.3
-
11
-
-
77958499974
-
Oncogenic function of the MUC1 receptor subunit in gene regulation
-
Kufe D: Oncogenic function of the MUC1 receptor subunit in gene regulation. Oncogene 29: 5663-5666, 2010.
-
(2010)
Oncogene
, vol.29
, pp. 5663-5666
-
-
Kufe, D.1
-
12
-
-
34547092962
-
Nuclear import of the MUC1-C oncoprotein is mediated by nucleoporin Nup62
-
DOI 10.1074/jbc.M703222200
-
Leng Y, Cao C, Ren J, et al: Nuclear import of the MUC1-C oncoprotein is mediated by nucleoporin Nup62. J Biol Chem 282: 19321-19330, 2007. (Pubitemid 47100108)
-
(2007)
Journal of Biological Chemistry
, vol.282
, Issue.27
, pp. 19321-19330
-
-
Leng, Y.1
Cao, C.2
Ren, J.3
Huang, L.4
Chen, D.5
Ito, M.6
Kufe, D.7
-
13
-
-
67449127094
-
Direct targeting of the MUC1 oncoprotein blocks survival and tumorigenicity of human breast carcinoma cells
-
Raina D, Ahmad R, Joshi M, et al: Direct targeting of the MUC1 oncoprotein blocks survival and tumorigenicity of human breast carcinoma cells. Cancer Res 69: 5133-5141, 2009.
-
(2009)
Cancer Res
, vol.69
, pp. 5133-5141
-
-
Raina, D.1
Ahmad, R.2
Joshi, M.3
-
14
-
-
70450268120
-
MUC1 oncoprotein is a druggable target in human prostate cancer cells
-
Joshi MD, Ahmad R, Raina D, et al: MUC1 oncoprotein is a druggable target in human prostate cancer cells. Mol Cancer Ther 8: 3056-3065, 2009.
-
(2009)
Mol Cancer Ther
, vol.8
, pp. 3056-3065
-
-
Joshi, M.D.1
Ahmad, R.2
Raina, D.3
-
15
-
-
77954897999
-
Survival of human multiple myeloma cells is dependent on MUC1 c-terminal transmembrane subunit oncoprotein function
-
Yin L, Ahmad R, Kosugi M, et al: Survival of human multiple myeloma cells is dependent on MUC1 c-terminal transmembrane subunit oncoprotein function. Mol Pharm 78: 166-174, 2010.
-
(2010)
Mol Pharm
, vol.78
, pp. 166-174
-
-
Yin, L.1
Ahmad, R.2
Kosugi, M.3
-
16
-
-
79955992775
-
Dependence on the MUC1-C oncoprotein in non-small cell lung cancer cells
-
Raina D, Kosugi M, Ahmad R, et al: Dependence on the MUC1-C oncoprotein in non-small cell lung cancer cells. Mol Cancer Ther 10: 806-816, 2011.
-
(2011)
Mol Cancer Ther
, vol.10
, pp. 806-816
-
-
Raina, D.1
Kosugi, M.2
Ahmad, R.3
-
18
-
-
0034633602
-
Hydrogen peroxide: A key messenger that modulates protein phosphorylation through cysteine oxidation
-
Rhee SG, Bae YS, Lee SR and Kwon J: Hydrogen peroxide: a key messenger that modulates protein phosphorylation through cysteine oxidation. Sci STKE 2000: pe1, 2000.
-
(2000)
Sci STKE
, vol.2000
-
-
Rhee, S.G.1
Bae, Y.S.2
Lee, S.R.3
Kwon, J.4
-
19
-
-
64549097266
-
Thiol-based redox switches in eukaryotic proteins
-
Brandes N, Schmitt S and Jakob U: Thiol-based redox switches in eukaryotic proteins. Antioxid Redox Signal 11: 997-1014, 2009.
-
(2009)
Antioxid Redox Signal
, vol.11
, pp. 997-1014
-
-
Brandes, N.1
Schmitt, S.2
Jakob, U.3
-
20
-
-
10744220453
-
Human MUC1 carcinoma-associated protein confers resistance to genotoxic anticancer agents
-
DOI 10.1016/S1535-6108(04)00020-0, PII S1535610804000200
-
Ren J, Agata N, Chen D, et al: Human MUC1 carcinoma-associated protein confers resistance to genotoxic anti-cancer agents. Cancer Cell 5: 163-175, 2004. (Pubitemid 38283802)
-
(2004)
Cancer Cell
, vol.5
, Issue.2
, pp. 163-175
-
-
Ren, J.1
Agata, N.2
Chen, D.3
Li, Y.4
Yu, W.-H.5
Huang, L.6
Raina, D.7
Chen, W.8
Kharbanda, S.9
Kufe, D.10
-
21
-
-
79960654379
-
Non-cysteine linked MUC1 cytoplasmic dimers are required for src recruitment and ICAM-1 binding induced cell invasion
-
Bernier AJ, Zhang J, Lillehoj E, Shaw AR, Gunasekara N and Hugh JC: Non-cysteine linked MUC1 cytoplasmic dimers are required for src recruitment and ICAM-1 binding induced cell invasion. Mol Cancer 10: 93, 2011.
-
(2011)
Mol Cancer
, vol.10
, pp. 93
-
-
Bernier, A.J.1
Zhang, J.2
Lillehoj, E.3
Shaw, A.R.4
Gunasekara, N.5
Hugh, J.C.6
-
22
-
-
0035893753
-
Oligomerization of green fluorescent protein in the secretory pathway of endocrine cells
-
DOI 10.1042/0264-6021:3600645
-
Jain RK, Joyce PB, Molinete M, Halban PA and Gorr SU: Oligomerization of green fluorescent protein in the secretory pathway of endocrine cells. Biochem J 360: 645-649, 2001. (Pubitemid 34020271)
-
(2001)
Biochemical Journal
, vol.360
, Issue.3
, pp. 645-649
-
-
Jain, R.K.1
Joyce, P.B.M.2
Molinete, M.3
Halban, P.A.4
Gorr, S.-U.5
-
23
-
-
3543095148
-
Monitoring disulfide bond formation in the eukaryotic cytosol
-
DOI 10.1083/jcb.200402120
-
Ostergaard H, Tachibana C and Winther JR: Monitoring disulfide bond formation in the eukaryotic cytosol. J Cell Biol 166: 337-345, 2004. (Pubitemid 39031237)
-
(2004)
Journal of Cell Biology
, vol.166
, Issue.3
, pp. 337-345
-
-
Ostergaard, H.1
Tachibana, C.2
Winther, J.R.3
-
24
-
-
46149125288
-
Quantifying changes in the thiol redox proteome upon oxidative stress in vivo
-
DOI 10.1073/pnas.0707723105
-
Leichert LI, Gehrke F, Gudiseva HV, et al: Quantifying changes in the thiol redox proteome upon oxidative stress in vivo. Proc Natl Acad Sci USA 105: 8197-8202, 2008. (Pubitemid 351904734)
-
(2008)
Proceedings of the National Academy of Sciences of the United States of America
, vol.105
, Issue.24
, pp. 8197-8202
-
-
Leichert, L.I.1
Gehrke, F.2
Gudiseva, H.V.3
Blackwell, T.4
Ilbert, M.5
Walker, A.K.6
Strahler, J.R.7
Andrews, P.C.8
Jakob, U.9
-
25
-
-
0042763566
-
Not every disulfide lasts forever: Disulfide bond formation as a redox switch
-
Linke K and Jakob U: Not every disulfide lasts forever: disulfide bond formation as a redox switch. Antioxid Redox Signal 5: 425-434, 2003. (Pubitemid 37087402)
-
(2003)
Antioxidants and Redox Signaling
, vol.5
, Issue.4
, pp. 425-434
-
-
Linke, K.1
Jakob, U.2
-
26
-
-
67650071137
-
Targeting cancer cells by ROS-mediated mechanisms: A radical therapeutic approach?
-
Trachootham D, Alexandre J and Huang P: Targeting cancer cells by ROS-mediated mechanisms: a radical therapeutic approach? Nat Rev Drug Discov 8: 579-591, 2009.
-
(2009)
Nat Rev Drug Discov
, vol.8
, pp. 579-591
-
-
Trachootham, D.1
Alexandre, J.2
Huang, P.3
-
27
-
-
64549108961
-
Redox regulation and its emerging roles in stem cells and stem-like cancer cells
-
Ogasawara MA and Zhang H: Redox regulation and its emerging roles in stem cells and stem-like cancer cells. Antioxid Redox Signal 11: 1107-1122, 2009.
-
(2009)
Antioxid Redox Signal
, vol.11
, pp. 1107-1122
-
-
Ogasawara, M.A.1
Zhang, H.2
-
28
-
-
79955979073
-
MUC1-C oncoprotein suppresses reactive oxygen species-induced terminal differentiation of acute myelogenous leukemia cells
-
Yin L, Wu Z, Avigan D, et al: MUC1-C oncoprotein suppresses reactive oxygen species-induced terminal differentiation of acute myelogenous leukemia cells. Blood 117: 4863-4870, 2011.
-
(2011)
Blood
, vol.117
, pp. 4863-4870
-
-
Yin, L.1
Wu, Z.2
Avigan, D.3
-
29
-
-
0042818006
-
Human MUC1 carcinoma antigen regulates intracellular oxidant levels and the apoptotic response to oxidative stress
-
DOI 10.1074/jbc.M301987200
-
Yin L and Kufe D: Human MUC1 carcinoma antigen regulates intracellular oxidant levels and the apoptotic response to oxidative stress. J Biol Chem 278: 35458-35464, 2003. (Pubitemid 37102316)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.37
, pp. 35458-35464
-
-
Yin, L.1
Li, Y.2
Ren, J.3
Kuwahara, H.4
Kufe, D.5
-
30
-
-
7944230166
-
MUC1 oncoprotein activates the FOXO3a transcription factor in a survival response to oxidative stress
-
DOI 10.1074/jbc.M408027200
-
Yin L, Huang L and Kufe D: MUC1 oncoprotein activates the foxo3a transcription factor in a survival response to oxidative stress. J Biol Chem 279: 45721-45727, 2004. (Pubitemid 39491562)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.44
, pp. 45721-45727
-
-
Yin, L.1
Huang, L.2
Kufe, D.3
-
31
-
-
33846994065
-
Mucin 1 oncoprotein blocks hypoxia-inducible factor 1alpha activation in a survival response to hypoxia
-
DOI 10.1074/jbc.M610156200
-
Yin L, Kharbanda S and Kufe D: Mucin 1 oncoprotein blocks hypoxia-inducible factor 1 alpha activation in a survival response to hypoxia. J Biol Chem 282: 257-266, 2007. (Pubitemid 47076647)
-
(2007)
Journal of Biological Chemistry
, vol.282
, Issue.1
, pp. 257-266
-
-
Yin, L.1
Kharbanda, S.2
Kufe, D.3
-
32
-
-
67649419014
-
MUC1 oncoprotein promotes autophagy in a survival response to glucose deprivation
-
Yin L, Kharbanda S and Kufe D: MUC1 oncoprotein promotes autophagy in a survival response to glucose deprivation. Int J Oncol 34: 1691-1699, 2009.
-
(2009)
Int J Oncol
, vol.34
, pp. 1691-1699
-
-
Yin, L.1
Kharbanda, S.2
Kufe, D.3
|