메뉴 건너뛰기




Volumn 42, Issue 4, 2014, Pages 623-631

Inhibition of the multidrug resistance P-glycoprotein: Time for a change of strategy?

Author keywords

[No Author keywords available]

Indexed keywords

DOXORUBICIN; MULTIDRUG RESISTANCE PROTEIN; NANOCARRIER; NANOPARTICLE; TARIQUIDAR; VERAPAMIL;

EID: 84896131650     PISSN: 00909556     EISSN: 1521009X     Source Type: Journal    
DOI: 10.1124/dmd.113.056176     Document Type: Short Survey
Times cited : (364)

References (167)
  • 2
    • 78049333901 scopus 로고    scopus 로고
    • pH-sensitive membrane peptides (pHLIPs) as a novel class of delivery agents
    • Andreev OA, Engelman DM, and Reshetnyak YK (2010) pH-sensitive membrane peptides (pHLIPs) as a novel class of delivery agents. Mol Membr Biol 27:341-352.
    • (2010) Mol Membr Biol , vol.27 , pp. 341-352
    • Andreev, O.A.1    Engelman, D.M.2    Reshetnyak, Y.K.3
  • 5
    • 0026716259 scopus 로고
    • Modulation of P-glycoprotein phosphorylation and drug transport by sodium butyrate
    • Bates SE, Currier SJ, Alvarez M, and Fojo AT (1992) Modulation of P-glycoprotein phosphorylation and drug transport by sodium butyrate. Biochemistry 31:6366-6372.
    • (1992) Biochemistry , vol.31 , pp. 6366-6372
    • Bates, S.E.1    Currier, S.J.2    Alvarez, M.3    Fojo, A.T.4
  • 6
    • 38849208598 scopus 로고    scopus 로고
    • Differential pharmacological regulation of drug efflux and pharmacoresistant schizophrenia
    • DOI 10.1002/bies.20706
    • Bebawy M and Chetty M (2008) Differential pharmacological regulation of drug efflux and pharmacoresistant schizophrenia. Bioessays 30:183-188. (Pubitemid 351196953)
    • (2008) BioEssays , vol.30 , Issue.2 , pp. 183-188
    • Bebawy, M.1    Chetty, M.2
  • 7
    • 70349306861 scopus 로고    scopus 로고
    • Membrane microparticles mediate transfer of P-glycoprotein to drug sensitive cancer cells
    • Bebawy M, Combes V, Lee E, Jaiswal R, Gong J, Bonhoure A, and Grau GE (2009) Membrane microparticles mediate transfer of P-glycoprotein to drug sensitive cancer cells. Leukemia 23: 1643-1649.
    • (2009) Leukemia , vol.23 , pp. 1643-1649
    • Bebawy, M.1    Combes, V.2    Lee, E.3    Jaiswal, R.4    Gong, J.5    Bonhoure, A.6    Grau, G.E.7
  • 8
    • 0035556276 scopus 로고    scopus 로고
    • Selective modulation of P-glycoprotein-mediated drug resistance
    • Bebawy M, Morris MB, and Roufogalis BD (2001) Selective modulation of P-glycoprotein-mediated drug resistance. Br J Cancer 85:1998-2003. (Pubitemid 34775339)
    • (2001) British Journal of Cancer , vol.85 , Issue.12 , pp. 1998-2003
    • Bebawy, M.1    Morris, M.B.2    Roufogalis, B.D.3
  • 9
    • 0017225040 scopus 로고
    • Pleiotropic phenotype of colchicine-resistant CHO cells: Cross-resistance and collateral sensitivity
    • Bech-Hansen NT, Till JE, and Ling V (1976) Pleiotropic phenotype of colchicine-resistant CHO cells: cross-resistance and collateral sensitivity. J Cell Physiol 88:23-31.
    • (1976) J Cell Physiol , vol.88 , pp. 23-31
    • Bech-Hansen, N.T.1    Till, J.E.2    Ling, V.3
  • 10
    • 0345357073 scopus 로고    scopus 로고
    • Transferrin-Containing, Cyclodextrin Polymer-Based Particles for Tumor-Targeted Gene Delivery
    • DOI 10.1021/bc034125f
    • Bellocq NC, Pun SH, Jensen GS, and Davis ME (2003) Transferrin- containing, cyclodextrin polymer-based particles for tumor-targeted gene delivery. Bioconjug Chem 14:1122-1132. (Pubitemid 37449039)
    • (2003) Bioconjugate Chemistry , vol.14 , Issue.6 , pp. 1122-1132
    • Bellocq, N.C.1    Pun, S.H.2    Jensen, G.S.3    Davis, M.E.4
  • 11
    • 0029864659 scopus 로고    scopus 로고
    • 2-deoxy-D-glucose toxicity and transport in human multidrug-resistant KB carcinoma cell lines
    • Bentley J, Bell SE, Quinn DM, Kellett GL, and Warr JR (1996) 2-deoxy-D-glucose toxicity and transport in human multidrug-resistant KB carcinoma cell lines. Oncol Res 8:77-84.
    • (1996) Oncol Res , vol.8 , pp. 77-84
    • Bentley, J.1    Bell, S.E.2    Quinn, D.M.3    Kellett, G.L.4    Warr, J.R.5
  • 12
    • 0031764330 scopus 로고    scopus 로고
    • Clinical relevance of transmembrane drug efflux as a mechanism of multidrug resistance
    • Bradshaw DM and Arceci RJ (1998) Clinical relevance of transmembrane drug efflux as a mechanism of multidrug resistance. J Clin Oncol 16:3674-3690. (Pubitemid 28506783)
    • (1998) Journal of Clinical Oncology , vol.16 , Issue.11 , pp. 3674-3690
    • Bradshaw, D.M.1    Arceci, R.J.2
  • 15
    • 33744826296 scopus 로고    scopus 로고
    • Cancer's sweet tooth
    • DOI 10.1016/j.ccr.2006.05.012, PII S1535610806001498
    • Bui T and Thompson CB (2006) Cancer's sweet tooth. Cancer Cell 9:419-420. (Pubitemid 43832194)
    • (2006) Cancer Cell , vol.9 , Issue.6 , pp. 419-420
    • Bui, T.1    Thompson, C.B.2
  • 18
    • 0029010879 scopus 로고
    • Collateral sensitivity of multidrug resistant cells to narcotic analgesics is due to effects on the plasma membrane
    • Callaghan R and Riordan JR (1995) Collateral sensitivity of multidrug resistant cells to narcotic analgesics is due to effects on the plasma membrane. Biochim Biophys Acta 1236:155-162.
    • (1995) Biochim Biophys Acta , vol.1236 , pp. 155-162
    • Callaghan, R.1    Riordan, J.R.2
  • 21
    • 84874134961 scopus 로고    scopus 로고
    • Doxorubicin-loaded micelles of reverse poly (butylene oxide)-poly(ethylene oxide)-poly(butylene oxide) block copolymers as efficient "active" chemotherapeutic agents
    • Cambón A, Rey-Rico A, Mistry D, Brea J, Loza MI, Attwood D, Barbosa S, Alvarez-Lorenzo C, Concheiro A, and Taboada P, et al. (2013b) Doxorubicin-loaded micelles of reverse poly (butylene oxide)-poly(ethylene oxide)-poly(butylene oxide) block copolymers as efficient "active" chemotherapeutic agents. Int J Pharm 445:47-57.
    • (2013) Int J Pharm , vol.445 , pp. 47-57
    • Cambón, A.1    Rey-Rico, A.2    Mistry, D.3    Brea, J.4    Loza, M.I.5    Attwood, D.6    Barbosa, S.7    Alvarez-Lorenzo, C.8    Concheiro, A.9    Taboada, P.10
  • 22
    • 0023235501 scopus 로고
    • Action of calcium antagonists on multidrug resistant cells. Specific cytotoxicity independent of increased cancer drug accumulation
    • Cano-Gauci DF and Riordan JR (1987) Action of calcium antagonists on multidrug resistant cells. Specific cytotoxicity independent of increased cancer drug accumulation. Biochem Pharmacol 36:2115-2123.
    • (1987) Biochem Pharmacol , vol.36 , pp. 2115-2123
    • Cano-Gauci, D.F.1    Riordan, J.R.2
  • 23
    • 0025318529 scopus 로고
    • Protein kinase C phosphorylates P-glycoprotein in multidrug resistant human KB carcinoma cells
    • Chambers TC, McAvoy EM, Jacobs JW, and Eilon G (1990) Protein kinase C phosphorylates P-glycoprotein in multidrug resistant human KB carcinoma cells. J Biol Chem 265:7679-7686.
    • (1990) J Biol Chem , vol.265 , pp. 7679-7686
    • Chambers, T.C.1    McAvoy, E.M.2    Jacobs, J.W.3    Eilon, G.4
  • 24
    • 0027460274 scopus 로고
    • Identification of specific sites in human P-glycoprotein phosphorylated by protein kinase C
    • Chambers TC, Pohl J, Raynor RL, and Kuo JF (1993) Identification of specific sites in human P-glycoprotein phosphorylated by protein kinase C. J Biol Chem 268:4592-4595. (Pubitemid 23081564)
    • (1993) Journal of Biological Chemistry , vol.268 , Issue.7 , pp. 4592-4595
    • Chambers, T.C.1    Pohl, J.2    Raynor, R.L.3    Kuo, J.F.4
  • 25
    • 0027076780 scopus 로고
    • Regulation by phorbol ester and protein kinase C inhibitors, and by a protein phosphatase inhibitor (okadaic acid), of P-glycoprotein phosphorylation and relationship to drug accumulation in multidrug-resistant human KB cells
    • Chambers TC, Zheng B, and Kuo JF (1992) Regulation by phorbol ester and protein kinase C inhibitors, and by a protein phosphatase inhibitor (okadaic acid), of P-glycoprotein phosphorylation and relationship to drug accumulation in multidrug-resistant human KB cells. Mol Pharmacol 41:1008-1015. (Pubitemid 23026098)
    • (1992) Molecular Pharmacology , vol.41 , Issue.6 , pp. 1008-1015
    • Chambers, T.C.1    Zheng, B.2    Kuo, J.F.3
  • 26
    • 0022972654 scopus 로고
    • Internal duplication and homology with bacterial transport proteins in the mdr1 (P-glycoprotein) gene from multidrug-resistant human cells
    • Chen CJ, Chin JE, Ueda K, Clark DP, Pastan I, Gottesman MM, and Roninson IB (1986) Internal duplication and homology with bacterial transport proteins in the mdr1 (P-glycoprotein) gene from multidrug-resistant human cells. Cell 47:381-389. (Pubitemid 17210152)
    • (1986) Cell , vol.47 , Issue.3 , pp. 381-389
    • Chen, C.-J.1    Chin, J.E.2    Ueda, K.3
  • 27
    • 84859376472 scopus 로고    scopus 로고
    • Molecular pathways: Regulation and therapeutic implications of multidrug resistance
    • Chen KG and Sikic BI (2012) Molecular pathways: regulation and therapeutic implications of multidrug resistance. Clin Cancer Res 18:1863-1869.
    • (2012) Clin Cancer Res , vol.18 , pp. 1863-1869
    • Chen, K.G.1    Sikic, B.I.2
  • 28
    • 84859269331 scopus 로고    scopus 로고
    • Computational models for predicting substrates or inhibitors of P-glycoprotein
    • Chen L, Li Y, Yu H, Zhang L, and Hou T (2012) Computational models for predicting substrates or inhibitors of P-glycoprotein. Drug Discov Today 17:343-351.
    • (2012) Drug Discov Today , vol.17 , pp. 343-351
    • Chen, L.1    Li, Y.2    Yu, H.3    Zhang, L.4    Hou, T.5
  • 30
    • 65349153918 scopus 로고    scopus 로고
    • Comparative proteomic analysis of paclitaxel sensitive A2780 epithelial ovarian cancer cell line and its resistant counterpart A2780TC1 by 2D-DIGE: The role of ERp57
    • Cicchillitti L, Di Michele M, Urbani A, Ferlini C, Donat MB, Scambia G, and Rotilio D (2009) Comparative proteomic analysis of paclitaxel sensitive A2780 epithelial ovarian cancer cell line and its resistant counterpart A2780TC1 by 2D-DIGE: the role of ERp57. J Proteome Res 8:1902-1912.
    • (2009) J Proteome Res , vol.8 , pp. 1902-1912
    • Cicchillitti, L.1    Di Michele, M.2    Urbani, A.3    Ferlini, C.4    Donat, M.B.5    Scambia, G.6    Rotilio, D.7
  • 32
    • 33747757697 scopus 로고    scopus 로고
    • Cerebral malaria: Role of microparticles and platelets in alterations of the blood-brain barrier
    • DOI 10.1016/j.ijpara.2006.02.005, PII S0020751906000634, Blood-Brain Barrier in Parasitic Disease
    • Combes V, Coltel N, Faille D, Wassmer SC, and Grau GE (2006) Cerebral malaria: role of microparticles and platelets in alterations of the blood-brain barrier. Int J Parasitol 36:541-546. (Pubitemid 44275316)
    • (2006) International Journal for Parasitology , vol.36 , Issue.5 , pp. 541-546
    • Combes, V.1    Coltel, N.2    Faille, D.3    Wassmer, S.C.4    Grau, G.E.5
  • 36
    • 0023234519 scopus 로고
    • Certain calcium channel blockers bind specifically to multidrug-resistant human KB carcinoma membrane vesicles and inhibit drug binding to P-glycoprotein
    • Cornwell MM, Pastan I, and Gottesman MM (1987) Certain calcium channel blockers bind specifically to multidrug-resistant human KB carcinoma membrane vesicles and inhibit drug binding to P-glycoprotein. J Biol Chem 262:2166-2170. (Pubitemid 17102655)
    • (1987) Journal of Biological Chemistry , vol.262 , Issue.5 , pp. 2166-2170
    • Cornwell, M.M.1    Pastan, I.2    Gottesman, M.M.3
  • 37
    • 73949136293 scopus 로고    scopus 로고
    • Generating inhibitors of P-glycoprotein: Where to, now?
    • Crowley E, McDevitt CA, and Callaghan R (2010) Generating inhibitors of P-glycoprotein: where to, now? Methods Mol Biol 596:405-432.
    • (2010) Methods Mol Biol , vol.596 , pp. 405-432
    • Crowley, E.1    McDevitt, C.A.2    Callaghan, R.3
  • 38
    • 0024506222 scopus 로고
    • Drug-resistance in multiple myeloma and non-Hodgkin's lymphoma: Detection of P-glycoprotein and potential circumvention by addition of verapamil to chemotherapy
    • Dalton WS, Grogan TM, Meltzer PS, Scheper RJ, Durie BG, Taylor CW, Miller TP, and Salmon SE (1989) Drug-resistance in multiple myeloma and non-Hodgkin's lymphoma: detection of P-glycoprotein and potential circumvention by addition of verapamil to chemotherapy. J Clin Oncol 7:415-424. (Pubitemid 19098134)
    • (1989) Journal of Clinical Oncology , vol.7 , Issue.4 , pp. 415-424
    • Dalton, W.S.1    Grogan, T.M.2    Meltzer, P.S.3    Scheper, R.J.4    Durie, B.G.M.5    Taylor, C.W.6    Miller, T.P.7    Salmon, S.E.8
  • 40
    • 35948984530 scopus 로고    scopus 로고
    • P-glycoprotein and breast cancer resistance protein: Two dominant transporters working together in limiting the brain penetration of topotecan
    • DOI 10.1158/1078-0432.CCR-07-1335
    • de Vries NA, Zhao J, Kroon E, Buckle T, Beijnen JH, and van Tellingen O (2007) P-glycoprotein and breast cancer resistance protein: two dominant transporters working together in limiting the brain penetration of topotecan. Clin Cancer Res 13:6440-6449. (Pubitemid 350075034)
    • (2007) Clinical Cancer Research , vol.13 , Issue.21 , pp. 6440-6449
    • DeVries, N.A.1    Zhao, J.2    Kroon, E.3    Buckle, T.4    Beijnen, J.H.5    Van Tellingen, O.6
  • 41
    • 0021032114 scopus 로고
    • Patterns of cross-resistance to the antifolate drugs trimetrexate, metoprine, homofolate, and CB3717 in human lymphoma and osteosarcoma cells resistant to methotrexate
    • Diddens H, Niethammer D, and Jackson RC (1983) Patterns of cross-resistance to the antifolate drugs trimetrexate, metoprine, homofolate, and CB3717 in human lymphoma and osteosarcoma cells resistant to methotrexate. Cancer Res 43:5286-5292. (Pubitemid 14230140)
    • (1983) Cancer Research , vol.43 , Issue.11 , pp. 5286-5292
    • Diddens, H.1    Niethammer, D.2    Jackson, R.C.3
  • 44
    • 84901999902 scopus 로고    scopus 로고
    • Tumor extracellular acidity-activated nanoparticles as drug delivery systems for enhanced cancer therapy
    • DOI: 10.1016/j.biotechadv.2013.08.002
    • Du J-Z, Mao C-Q, Yuan Y-Y, Yang X-Z, and Wang J (2013) Tumor extracellular acidity-activated nanoparticles as drug delivery systems for enhanced cancer therapy. Biotechnol Adv DOI: 10.1016/j.biotechadv.2013.08.002.
    • (2013) Biotechnol Adv
    • Du, J.-Z.1    Mao, C.-Q.2    Yuan, Y.-Y.3    Yang, X.-Z.4    Wang, J.5
  • 45
    • 0020551668 scopus 로고
    • Procoagulant activity associated with plasma membrane vesicles shed by cultured tumor cells
    • Dvorak HF, Van DeWater L, Bitzer AM, Dvorak AM, Anderson D, Harvey VS, Bach R, Davis GL, DeWolf W, and Carvalho AC (1983) Procoagulant activity associated with plasma membrane vesicles shed by cultured tumor cells. Cancer Res 43:4434-4442. (Pubitemid 13041884)
    • (1983) Cancer Research , vol.43 , Issue.9 , pp. 4434-4442
    • Dvorak, H.F.1    Van De, W.L.2    Bitzer, A.M.3
  • 46
    • 0036136534 scopus 로고    scopus 로고
    • A pharmacophore for human pregnane X receptor ligands
    • DOI 10.1124/dmd.30.1.96
    • Ekins S and Erickson JA (2002) A pharmacophore for human pregnane X receptor ligands. Drug Metab Dispos 30:96-99. (Pubitemid 34016946)
    • (2002) Drug Metabolism and Disposition , vol.30 , Issue.1 , pp. 96-99
    • Ekins, S.1    Erickson, J.A.2
  • 47
    • 33646257222 scopus 로고    scopus 로고
    • Selective laser photo-thermal therapy of epithelial carcinoma using anti-EGFR antibody conjugated gold nanoparticles
    • DOI 10.1016/j.canlet.2005.07.035, PII S0304383505007378
    • El-Sayed IH, Huang X, and El-Sayed MA (2006) Selective laser photo-thermal therapy of epithelial carcinoma using anti-EGFR antibody conjugated gold nanoparticles. Cancer Lett 239:129-135. (Pubitemid 43946581)
    • (2006) Cancer Letters , vol.239 , Issue.1 , pp. 129-135
    • El-Sayed, I.H.1    Huang, X.2    El-Sayed, M.A.3
  • 49
    • 0033969525 scopus 로고    scopus 로고
    • Analysis of the tangled relationships between P-glycoprotein-mediated multidrug resistance and the lipid phase of the cell membrane
    • Ferté J (2000) Analysis of the tangled relationships between P-glycoprotein-mediated multidrug resistance and the lipid phase of the cell membrane. Eur J Biochem 267:277-294.
    • (2000) Eur J Biochem , vol.267 , pp. 277-294
    • Ferté, J.1
  • 50
    • 0141609786 scopus 로고    scopus 로고
    • Cellular microparticles: What are they bad or good for?
    • Freyssinet JM (2003) Cellular microparticles: what are they bad or good for? J Thromb Haemost 1:1655-1662.
    • (2003) J Thromb Haemost , vol.1 , pp. 1655-1662
    • Freyssinet, J.M.1
  • 51
    • 77949274538 scopus 로고    scopus 로고
    • Formation of procoagulant microparticles and properties
    • Freyssinet JM and Toti F (2010) Formation of procoagulant microparticles and properties. Thromb Res 125 (Suppl 1):S46-S48.
    • (2010) Thromb Res , vol.125 , Issue.SUPPL. 1
    • Freyssinet, J.M.1    Toti, F.2
  • 52
    • 0030669086 scopus 로고    scopus 로고
    • Polyethylene glycol-coated (pegylated) liposomal doxorubicin. Rationale for use in solid tumours
    • Gabizon A and Martin F (1997) Polyethylene glycol-coated (pegylated) liposomal doxorubicin. Rationale for use in solid tumours. Drugs 54 (Suppl 4):15-21. (Pubitemid 27487791)
    • (1997) Drugs , vol.54 , Issue.SUPPL. 4 , pp. 15-21
    • Gabizon, A.1    Martin, F.2
  • 53
    • 78649934086 scopus 로고    scopus 로고
    • pH-Responsive nanoparticles for drug delivery
    • Gao W, Chan JM, and Farokhzad OC (2010) pH-Responsive nanoparticles for drug delivery. Mol Pharm 7:1913-1920.
    • (2010) Mol Pharm , vol.7 , pp. 1913-1920
    • Gao, W.1    Chan, J.M.2    Farokhzad, O.C.3
  • 54
    • 0035805536 scopus 로고    scopus 로고
    • Nuclear receptor response elements mediate induction of intestinal MDR1 by rifampin
    • Geick A, Eichelbaum M, and Burk O (2001) Nuclear receptor response elements mediate induction of intestinal MDR1 by rifampin. J Biol Chem 276:14581-14587.
    • (2001) J Biol Chem , vol.276 , pp. 14581-14587
    • Geick, A.1    Eichelbaum, M.2    Burk, O.3
  • 57
    • 35448940364 scopus 로고    scopus 로고
    • Adaptive landscapes and emergent phenotypes: Why do cancers have high glycolysis?
    • DOI 10.1007/s10863-007-9085-y, Special Topic: The Warburg Effect: Its Continued Impact on Cancer Research into the 21st Century
    • Gillies RJ and Gatenby RA (2007) Adaptive landscapes and emergent phenotypes: why do cancers have high glycolysis? J Bioenerg Biomembr 39:251-257. (Pubitemid 47619378)
    • (2007) Journal of Bioenergetics and Biomembranes , vol.39 , Issue.3 , pp. 251-257
    • Gillies, R.J.1    Gatenby, R.A.2
  • 58
    • 0030758034 scopus 로고    scopus 로고
    • Urokinase plasminogen activator and gelatinases are associated with membrane vesicles shed by human HT1080 fibrosarcoma cells
    • DOI 10.1074/jbc.272.27.17216
    • Ginestra A, Monea S, Seghezzi G, Dolo V, Nagase H, Mignatti P, and Vittorelli ML (1997) Urokinase plasminogen activator and gelatinases are associated with membrane vesicles shed by human HT1080 fibrosarcoma cells. J Biol Chem 272:17216-17222. (Pubitemid 27289836)
    • (1997) Journal of Biological Chemistry , vol.272 , Issue.27 , pp. 17216-17222
    • Ginestra, A.1    Monea, S.2    Seghezzi, G.3    Dolo, V.4    Nagase, H.5    Mignatti, P.6    Vittorelli, M.L.7
  • 59
    • 0036272752 scopus 로고    scopus 로고
    • Effects of ATP depletion and phosphate analogues on P-glycoprotein conformation in live cells
    • DOI 10.1046/j.1432-1033.2002.02929.x
    • Goda K, Nagy H, Mechetner E, Cianfriglia M, and Szabó G, Jr (2002) Effects of ATP depletion and phosphate analogues on P-glycoprotein conformation in live cells. Eur J Biochem 269:2672-2677. (Pubitemid 34595633)
    • (2002) European Journal of Biochemistry , vol.269 , Issue.11 , pp. 2672-2677
    • Goda, K.1    Nagy, H.2    Mechetner, E.3    Cianfriglia, M.4    Szabo Jr., G.5
  • 62
    • 0029889967 scopus 로고    scopus 로고
    • Protein kinase C-mediated phosphorylation does not regulate drug transport by the human multidrug resistance P-glycoprotein
    • DOI 10.1074/jbc.271.23.13668
    • Goodfellow HR, Sardini A, Ruetz S, Callaghan R, Gros P, McNaughton PA, and Higgins CF (1996) Protein kinase C-mediated phosphorylation does not regulate drug transport by the human multidrug resistance P-glycoprotein. J Biol Chem 271:13668-13674. (Pubitemid 26185417)
    • (1996) Journal of Biological Chemistry , vol.271 , Issue.23 , pp. 13668-13674
    • Goodfellow, H.R.1    Sardini, A.2    Ruetz, S.3    Callaghan, R.4    Gros, P.5    McNaughton, P.A.6    Higgins, C.F.7
  • 63
    • 0036364467 scopus 로고    scopus 로고
    • Multidrug resistance in cancer: Role of ATP-dependent transporters
    • Gottesman MM, Fojo T, and Bates SE (2002) Multidrug resistance in cancer: role of ATP-dependent transporters. Nat Rev Cancer 2:48-58. (Pubitemid 37328807)
    • (2002) Nature Reviews Cancer , vol.2 , Issue.1 , pp. 48-58
    • Gottesman, M.M.1    Fojo, T.2    Bates, S.E.3
  • 64
    • 0022993652 scopus 로고
    • Mammalian multidrug resistance gene: Complete cDNA sequence indicates strong homology to bacterial transport proteins
    • Gros P, Croop J, and Housman D (1986) Mammalian multidrug resistance gene: complete cDNA sequence indicates strong homology to bacterial transport proteins. Cell 47:371-380. (Pubitemid 17210151)
    • (1986) Cell , vol.47 , Issue.3 , pp. 371-380
    • Gros, P.1    Croop, J.2    Housman, D.3
  • 65
    • 0021868158 scopus 로고
    • Cross-resistance of vinblastine- and taxol-resistant mutants of Chinese hamster ovary cells to other anticancer drugs
    • Gupta RS (1985) Cross-resistance of vinblastine- and taxol-resistant mutants of Chinese hamster ovary cells to other anticancer drugs. Cancer Treat Rep 69:515-521.
    • (1985) Cancer Treat Rep , vol.69 , pp. 515-521
    • Gupta, R.S.1
  • 68
    • 80051869659 scopus 로고    scopus 로고
    • Synthesis and structure-activity evaluation of isatin-β- thiosemicarbazones with improved selective activity toward multidrug-resistant cells expressing P-glycoprotein
    • Hall MD, Brimacombe KR, Varonka MS, Pluchino KM, Monda JK, Li J, Walsh MJ, Boxer MB, Warren TH, and Fales HM, et al. (2011) Synthesis and structure-activity evaluation of isatin-β-thiosemicarbazones with improved selective activity toward multidrug-resistant cells expressing P-glycoprotein. J Med Chem 54:5878-5889.
    • (2011) J Med Chem , vol.54 , pp. 5878-5889
    • Hall, M.D.1    Brimacombe, K.R.2    Varonka, M.S.3    Pluchino, K.M.4    Monda, J.K.5    Li, J.6    Walsh, M.J.7    Boxer, M.B.8    Warren, T.H.9    Fales, H.M.10
  • 70
    • 0018775658 scopus 로고
    • Collateral sensitivity to methotrexate in cells resistant to adriamycin
    • Herman TS, Cress AE, and Gerner EW (1979) Collateral sensitivity to methotrexate in cells resistant to adriamycin. Cancer Res 39:1937-1942. (Pubitemid 9184981)
    • (1979) Cancer Research , vol.39 , Issue.6 I , pp. 1937-1942
    • Herman, T.S.1    Cress, A.E.2    Gerner, E.W.3
  • 71
  • 73
    • 0032953002 scopus 로고    scopus 로고
    • Platelet microparticles: A wide-angle perspective
    • DOI 10.1016/S1040-8428(98)00044-4, PII S1040842898000444
    • Horstman LL and Ahn YS (1999) Platelet microparticles: a wide-angle perspective. Crit Rev Oncol Hematol 30:111-142. (Pubitemid 29232249)
    • (1999) Critical Reviews in Oncology/Hematology , vol.30 , Issue.2 , pp. 111-142
    • Horstman, L.L.1    Ahn, Y.S.2
  • 75
    • 35548945424 scopus 로고    scopus 로고
    • 100 cells by Gynostemma pentaphyllum extract
    • DOI 10.1016/j.phymed.2007.09.006, PII S0944711307002218
    • Huang TH, Bebawy M, Tran VH, and Roufogalis BD (2007) Specific reversal of multidrug resistance to colchicine in CEM/VLB(100) cells by Gynostemma pentaphyllum extract. Phytomedicine 14:830-839. (Pubitemid 350016828)
    • (2007) Phytomedicine , vol.14 , Issue.12 , pp. 830-839
    • Huang, T.H.-W.1    Bebawy, M.2    Tran, V.H.3    Roufogalis, B.D.4
  • 78
    • 84876079106 scopus 로고    scopus 로고
    • Breast cancer-derived microparticles display tissue selectivity in the transfer of resistance proteins to cells
    • Jaiswal R, Luk F, Dalla PV, Grau GE, and Bebawy M (2013) Breast cancer-derived microparticles display tissue selectivity in the transfer of resistance proteins to cells. PLoS ONE 8: e61515.
    • (2013) PLoS ONE , vol.8
    • Jaiswal, R.1    Luk, F.2    Dalla, P.V.3    Grau, G.E.4    Bebawy, M.5
  • 79
    • 84861951099 scopus 로고    scopus 로고
    • Microparticle conferred microRNA profiles - implications in the transfer and dominance of cancer traits
    • DOI: 10.1186/1476-4598-11-37 [published ahead of print]
    • Jaiswal R, Luk F, Gong J, Mathys JM, Grau GE, and Bebawy M (2012b) Microparticle conferred microRNA profiles - implications in the transfer and dominance of cancer traits. Mol Cancer DOI: 10.1186/1476-4598-11-37 [published ahead of print].
    • (2012) Mol Cancer
    • Jaiswal, R.1    Luk, F.2    Gong, J.3    Mathys, J.M.4    Grau, G.E.5    Bebawy, M.6
  • 80
    • 0026439902 scopus 로고
    • Doxorubicin sensitivity pattern in a panel of small-cell lung-cancer cell lines: Correlation to etoposide and vincristine sensitivity and inverse correlation to carmustine sensitivity
    • Jensen PB, Roed H, Sehested M, Demant EJ, Vindeløv L, Christensen IJ, and Hansen HH (1992) Doxorubicin sensitivity pattern in a panel of small-cell lung-cancer cell lines: correlation to etoposide and vincristine sensitivity and inverse correlation to carmustine sensitivity. Cancer Chemother Pharmacol 31:46-52.
    • (1992) Cancer Chemother Pharmacol , vol.31 , pp. 46-52
    • Jensen, P.B.1    Roed, H.2    Sehested, M.3    Demant, E.J.4    Vindeløv, L.5    Christensen, I.J.6    Hansen, H.H.7
  • 81
    • 33645830172 scopus 로고
    • A surface glycoprotein modulating drug permeability in Chinese hamster ovary cell mutants
    • Juliano RL and Ling V (1976) A surface glycoprotein modulating drug permeability in Chinese hamster ovary cell mutants. Biochem Biophys Acta 455:152-162.
    • (1976) Biochem Biophys Acta , vol.455 , pp. 152-162
    • Juliano, R.L.1    Ling, V.2
  • 82
    • 0021852930 scopus 로고
    • Detection of P-glycoprotein in multidrug-resistant cell lines by monoclonal antibodies
    • DOI 10.1038/316820a0
    • Kartner N, Evernden-Porelle D, Bradley G, and Ling V (1985) Detection of P-glycoprotein in multidrug-resistant cell lines by monoclonal antibodies. Nature 316:820-823. (Pubitemid 15003741)
    • (1985) Nature , vol.316 , Issue.6031 , pp. 820-823
    • Kartner, N.1    Evernden-Porelle, D.2    Bradley, G.3    Ling, V.4
  • 83
    • 0142095072 scopus 로고    scopus 로고
    • A Mechanism for P-Glycoprotein-Mediated Apoptosis As Revealed by Verapamil Hypersensitivity
    • DOI 10.1021/bi034149+
    • Karwatsky J, Lincoln MC, and Georges E (2003) A mechanism for P-glycoprotein-mediated apoptosis as revealed by verapamil hypersensitivity. Biochemistry 42:12163-12173. (Pubitemid 37296492)
    • (2003) Biochemistry , vol.42 , Issue.42 , pp. 12163-12173
    • Karwatsky, J.1    Lincoln, M.C.2    Georges, E.3
  • 84
    • 84874884710 scopus 로고    scopus 로고
    • Modeling cyclosporine A inhibition of the distribution of a P-glycoprotein PET ligand, 11C-verapamil, into the maternal brain and fetal liver of the pregnant nonhuman primate: Impact of tissue blood flow and site of inhibition
    • Ke AB, Eyal S, Chung FS, Link JM, Mankoff DA, Muzi M, and Unadkat JD (2013) Modeling cyclosporine A inhibition of the distribution of a P-glycoprotein PET ligand, 11C-verapamil, into the maternal brain and fetal liver of the pregnant nonhuman primate: impact of tissue blood flow and site of inhibition. J Nucl Med 54:437-446.
    • (2013) J Nucl Med , vol.54 , pp. 437-446
    • Ke, A.B.1    Eyal, S.2    Chung, F.S.3    Link, J.M.4    Mankoff, D.A.5    Muzi, M.6    Unadkat, J.D.7
  • 85
    • 0036830046 scopus 로고    scopus 로고
    • Extracellular membrane vesicles from tumor cells promote angiogenesis via sphingomyelin
    • Kim CW, Lee HM, Lee TH, Kang C, Kleinman HK, and Gho YS (2002) Extracellular membrane vesicles from tumor cells promote angiogenesis via sphingomyelin. Cancer Res 62:6312-6317. (Pubitemid 35244486)
    • (2002) Cancer Research , vol.62 , Issue.21 , pp. 6312-6317
    • Kim, C.W.1    Lee, H.M.2    Lee, T.H.3    Kang, C.4    Kleinman, H.K.5    Gho, Y.S.6
  • 87
    • 34247543067 scopus 로고    scopus 로고
    • In vitro activity of novel dual action MDR anthranilamide modulators with inhibitory activity on CYP-450 (Part 2)
    • DOI 10.1016/j.bmc.2007.03.014, PII S0968089607002039
    • Labrie P, Maddaford SP, Lacroix J, Catalano C, Lee DK, Rakhit S, and Gaudreault RC (2007) In vitro activity of novel dual action MDR anthranilamide modulators with inhibitory activity on CYP-450 (Part 2). Bioorg Med Chem 15:3854-3868. (Pubitemid 46661801)
    • (2007) Bioorganic and Medicinal Chemistry , vol.15 , Issue.11 , pp. 3854-3868
    • Labrie, P.1    Maddaford, S.P.2    Lacroix, J.3    Catalano, C.4    Lee, D.K.H.5    Rakhit, S.6    Gaudreault, R.C.7
  • 88
    • 0242610852 scopus 로고    scopus 로고
    • Glucose Depletion Enhances P-Glycoprotein Expression in Hepatoma Cells: Role of Endoplasmic Reticulum Stress Response
    • Ledoux S, Yang R, Friedlander G, and Laouari D (2003) Glucose depletion enhances P-glycoprotein expression in hepatoma cells: role of endoplasmic reticulum stress response. Cancer Res 63:7284-7290. (Pubitemid 37413469)
    • (2003) Cancer Research , vol.63 , Issue.21 , pp. 7284-7290
    • Ledoux, S.1    Yang, R.2    Friedlander, G.3    Laouari, D.4
  • 89
    • 0141888537 scopus 로고    scopus 로고
    • The role of ABC transporters in clinical practice
    • DOI 10.1634/theoncologist.8-5-411
    • Leonard GD, Fojo T, and Bates SE (2003) The role of ABC transporters in clinical practice. Oncologist 8:411-424. (Pubitemid 37238869)
    • (2003) Oncologist , vol.8 , Issue.5 , pp. 411-424
    • Leonard, G.D.1    Fojo, T.2    Bates, S.E.3
  • 90
    • 17544368685 scopus 로고    scopus 로고
    • Multidrug resistance proteins: Role of P-glycoprotein, MRP1, MRP2, and BCRP (ABCG2) in tissue defense
    • DOI 10.1016/j.taap.2004.10.012, Membrane Transporters in Toxicology
    • Leslie EM, Deeley RG, and Cole SP (2005) Multidrug resistance proteins: role of P-glycoprotein, MRP1, MRP2, and BCRP (ABCG2) in tissue defense. Toxicol Appl Pharmacol 204:216-237. (Pubitemid 40552845)
    • (2005) Toxicology and Applied Pharmacology , vol.204 , Issue.3 , pp. 216-237
    • Leslie, E.M.1    Deeley, R.G.2    Cole, S.P.C.3
  • 91
    • 84883095688 scopus 로고    scopus 로고
    • Microparticles mediate MRP1 intercellular transfer and the re-templating of intrinsic resistance pathways
    • Lu JF, Luk F, Gong J, Jaiswal R, Grau GE, and Bebawy M (2013) Microparticles mediate MRP1 intercellular transfer and the re-templating of intrinsic resistance pathways. Pharmacol Res 76:77-83.
    • (2013) Pharmacol Res , vol.76 , pp. 77-83
    • Lu, J.F.1    Luk, F.2    Gong, J.3    Jaiswal, R.4    Grau, G.E.5    Bebawy, M.6
  • 92
    • 65549143860 scopus 로고    scopus 로고
    • Epidermal growth factor receptor-targeted gelatin-based engineered nanocarriers for DNA delivery and transfection in human pancreatic cancer cells
    • Magadala P and Amiji M (2008) Epidermal growth factor receptor-targeted gelatin-based engineered nanocarriers for DNA delivery and transfection in human pancreatic cancer cells. AAPS J 10:565-576.
    • (2008) AAPS J , vol.10 , pp. 565-576
    • Magadala, P.1    Amiji, M.2
  • 93
    • 0023272741 scopus 로고
    • Adriamycin resistance in HL60 cells and accompanying modification of a surface membrane protein contained in drug-sensitive cells
    • Marsh W and Center MS (1987) Adriamycin resistance in HL60 cells and accompanying modification of a surface membrane protein contained in drug-sensitive cells. Cancer Res 47:5080-5086. (Pubitemid 17146476)
    • (1987) Cancer Research , vol.47 , Issue.19 , pp. 5080-5086
    • Marsh, W.1    Center, M.S.2
  • 94
    • 0027739876 scopus 로고
    • Evidence of post-translational regulation of P-glycoprotein associated with the expression of a distinctive multiple drug-resistant phenotype in Chinese hamster ovary cells
    • DOI 10.1016/0959-8049(93)90215-2
    • McClean S and Hill BT (1993) Evidence of post-translational regulation of P-glycoprotein associated with the expression of a distinctive multiple drug-resistant phenotype in Chinese hamster ovary cells. Eur J Cancer 29A:2243-2248. (Pubitemid 24053001)
    • (1993) European Journal of Cancer Part A: General Topics , vol.29 , Issue.16 , pp. 2243-2248
    • McClean, S.1    Hill, B.T.2
  • 97
    • 0023508529 scopus 로고
    • Phosphorylation of the multidrug resistance associated glycoprotein
    • DOI 10.1021/bi00396a005
    • Mellado W and Horwitz SB (1987) Phosphorylation of the multidrug resistance associated glycoprotein. Biochemistry 26:6900-6904. (Pubitemid 18006248)
    • (1987) Biochemistry , vol.26 , Issue.22 , pp. 6900-6904
    • Mellado, W.1    Horwitz, S.B.2
  • 98
    • 43449133278 scopus 로고    scopus 로고
    • Resistance to chemotherapy in cancer: A complex and integrated cellular response
    • DOI 10.1159/000115967
    • Mellor HR and Callaghan R (2008) Resistance to chemotherapy in cancer: a complex and integrated cellular response. Pharmacology 81:275-300. (Pubitemid 351666917)
    • (2008) Pharmacology , vol.81 , Issue.4 , pp. 275-300
    • Mellor, H.R.1    Callaghan, R.2
  • 99
    • 33645756588 scopus 로고    scopus 로고
    • Relevance of multidrug resistance proteins on the clinical efficacy of cancer therapy
    • Merino V, Jiménez-Torres NV, and Merino-Sanjuán M (2004) Relevance of multidrug resistance proteins on the clinical efficacy of cancer therapy. Curr Drug Deliv 1:203-212.
    • (2004) Curr Drug Deliv , vol.1 , pp. 203-212
    • Merino, V.1    Jiménez-Torres, N.V.2    Merino-Sanjuán, M.3
  • 100
    • 0024823048 scopus 로고
    • Protein phosphorylation in multidrug resistant Chinese hamster cells
    • Meyers MB (1989) Protein phosphorylation in multidrug resistant Chinese hamster cells. Cancer Commun 1:233-241.
    • (1989) Cancer Commun , vol.1 , pp. 233-241
    • Meyers, M.B.1
  • 101
    • 80052552395 scopus 로고    scopus 로고
    • Therapeutic efficacy and safety of paclitaxel/lonidamine loaded EGFR-targeted nanoparticles for the treatment of multi-drug resistant cancer
    • Milane L, Duan Z, and Amiji M (2011) Therapeutic efficacy and safety of paclitaxel/lonidamine loaded EGFR-targeted nanoparticles for the treatment of multi-drug resistant cancer. PLoS ONE 6:e24075.
    • (2011) PLoS ONE , vol.6
    • Milane, L.1    Duan, Z.2    Amiji, M.3
  • 102
    • 33745852782 scopus 로고    scopus 로고
    • Modulation of multidrug resistance efflux pump activity to overcome chemoresistance in cancer
    • DOI 10.1016/j.coph.2006.01.009, PII S1471489206000798
    • Modok S, Mellor HR, and Callaghan R (2006) Modulation of multidrug resistance efflux pump activity to overcome chemoresistance in cancer. Curr Opin Pharmacol 6:350-354. (Pubitemid 44026037)
    • (2006) Current Opinion in Pharmacology , vol.6 , Issue.4 , pp. 350-354
    • Modok, S.1    Mellor, H.R.2    Callaghan, R.3
  • 103
    • 3242667696 scopus 로고    scopus 로고
    • Cellular microparticles: A disseminated storage pool of bioactive vascular effectors
    • DOI 10.1097/01.moh.0000131441.10020.87
    • Morel O, Toti F, Hugel B, and Freyssinet JM (2004) Cellular microparticles: a disseminated storage pool of bioactive vascular effectors. Curr Opin Hematol 11:156-164. (Pubitemid 38952003)
    • (2004) Current Opinion in Hematology , vol.11 , Issue.3 , pp. 156-164
    • Morel, O.1    Toti, F.2    Hugel, B.3    Freyssinet, J.-M.4
  • 104
    • 0029003904 scopus 로고
    • P-glycoprotein stability is affected by serum deprivation and high cell density in multidrug-resistant cells
    • Muller C, Laurent G, and Ling V (1995) P-glycoprotein stability is affected by serum deprivation and high cell density in multidrug-resistant cells. J Cell Physiol 163:538-544.
    • (1995) J Cell Physiol , vol.163 , pp. 538-544
    • Muller, C.1    Laurent, G.2    Ling, V.3
  • 107
    • 33845544335 scopus 로고    scopus 로고
    • Effect of nifedipine on adiponectin in hypertensive patients with type 2 diabetes mellitus
    • DOI 10.1038/sj.jhh.1002100, PII 1002100
    • Nomura S, Inami N, Kimura Y, Omoto S, Shouzu A, Nishikawa M, and Iwasaka T (2007) Effect of nifedipine on adiponectin in hypertensive patients with type 2 diabetes mellitus. J Hum Hypertens 21:38-44. (Pubitemid 44929342)
    • (2007) Journal of Human Hypertension , vol.21 , Issue.1 , pp. 38-44
    • Nomura, S.1    Inami, N.2    Kimura, Y.3    Omoto, S.4    Shouzu, A.5    Nishikawa, M.6    Iwasaka, T.7
  • 108
    • 51349130861 scopus 로고    scopus 로고
    • Function and role of microparticles in various clinical settings
    • Nomura S, Ozaki Y, and Ikeda Y (2008) Function and role of microparticles in various clinical settings. Thromb Res 123:8-23.
    • (2008) Thromb Res , vol.123 , pp. 8-23
    • Nomura, S.1    Ozaki, Y.2    Ikeda, Y.3
  • 109
    • 21744456906 scopus 로고    scopus 로고
    • Benidipine improves oxidized LDL-dependent monocyte and endothelial dysfunction in hypertensive patients with type 2 diabetes mellitus
    • DOI 10.1038/sj.jhh.1001863
    • Nomura S, Shouzu A, Omoto S, Nishikawa M, and Iwasaka T (2005) Benidipine improves oxidized LDL-dependent monocyte and endothelial dysfunction in hypertensive patients with type 2 diabetes mellitus. J Hum Hypertens 19:551-557. (Pubitemid 40946040)
    • (2005) Journal of Human Hypertension , vol.19 , Issue.7 , pp. 551-557
    • Nomura, S.1    Shouzu, A.2    Omoto, S.3    Nishikawa, M.4    Iwasaka, T.5
  • 110
    • 2342479742 scopus 로고    scopus 로고
    • Probucol and ticlopidine: Effect on platelet and monocyte activation markers in hyperlipidemic patients with and without type 2 diabetes
    • DOI 10.1016/j.atherosclerosis.2004.01.027, PII S0021915004000887
    • Nomura S, Takahashi N, Inami N, Kajiura T, Yamada K, Nakamori H, and Tsuda N (2004) Probucol and ticlopidine: effect on platelet and monocyte activation markers in hyperlipidemic patients with and without type 2 diabetes. Atherosclerosis 174:329-335. (Pubitemid 38597090)
    • (2004) Atherosclerosis , vol.174 , Issue.2 , pp. 329-335
    • Nomura, S.1    Takahashi, N.2    Inami, N.3    Kajiura, T.4    Yamada, K.5    Nakamori, H.6    Tsuda, N.7
  • 111
    • 0025153516 scopus 로고
    • Collateral drug sensitivity induced in CPT-11 (a novel derivative of camptothecin)-resistant cell lines
    • DOI 10.1016/0753-3322(90)90026-6
    • Oguro M, Seki Y, Okada K, and Andoh T (1990) Collateral drug sensitivity induced in CPT-11 (a novel derivative of camptothecin)-resistant cell lines. Biomed Pharmacother 44:209-216. (Pubitemid 20326782)
    • (1990) Biomedicine and Pharmacotherapy , vol.44 , Issue.4 , pp. 209-216
    • Oguro, M.1    Seki, Y.2    Okada, K.3    Andoh, T.4
  • 113
    • 0027362087 scopus 로고
    • Identification of the major phosphorylation domain of murine mdr1b P- glycoprotein. Analysis of the protein kinase A and protein kinase C phosphorylation sites
    • Orr GA, Han EK, Browne PC, Nieves E, O'Connor BM, Yang CP, and Horwitz SB (1993) Identification of the major phosphorylation domain of murine mdr1b P-glycoprotein. Analysis of the protein kinase A and protein kinase C phosphorylation sites. J Biol Chem 268: 25054-25062. (Pubitemid 23335528)
    • (1993) Journal of Biological Chemistry , vol.268 , Issue.33 , pp. 25054-25062
    • Orr, G.A.1    Han, E.K.-H.2    Browne, P.C.3    Nieves, E.4    O'Connor, B.M.5    Yang -, C.P.H.6    Horwitz, S.B.7
  • 114
    • 0023237840 scopus 로고
    • Verapamil and adriamycin in the treatment of drug-resistant ovarian cancer patients
    • Ozols RF, Cunnion RE, Klecker RW, Jr, Hamilton TC, Ostchega Y, Parrillo JE, and Young RC (1987) Verapamil and adriamycin in the treatment of drug-resistant ovarian cancer patients. J Clin Oncol 5:641-647. (Pubitemid 17062504)
    • (1987) Journal of Clinical Oncology , vol.5 , Issue.4 , pp. 641-647
    • Ozols, R.F.1    Cunnion, R.E.2    Klecker Jr., R.W.3
  • 115
    • 73849165351 scopus 로고
    • The prediction of growth-inhibitory drug combinations showing enhanced differential toxicity and collateral sensitivity
    • Paigen K (1962) The prediction of growth-inhibitory drug combinations showing enhanced differential toxicity and collateral sensitivity. Cancer Res 22:1290-1296.
    • (1962) Cancer Res , vol.22 , pp. 1290-1296
    • Paigen, K.1
  • 118
    • 84887121132 scopus 로고    scopus 로고
    • PHII-7 inhibits cell growth and induces apoptosis in leukemia cell line K562 as well as its MDR- counterpart K562/A02 through producing reactive oxygen species
    • Peng H, Yuan X, Shi R, Wei X, Ren S, Yan C, Ding Y, Lin Y, Fan D, and Yang M, et al. (2013) PHII-7 inhibits cell growth and induces apoptosis in leukemia cell line K562 as well as its MDR- counterpart K562/A02 through producing reactive oxygen species. Eur J Pharmacol 718:459-468.
    • (2013) Eur J Pharmacol , vol.718 , pp. 459-468
    • Peng, H.1    Yuan, X.2    Shi, R.3    Wei, X.4    Ren, S.5    Yan, C.6    Ding, Y.7    Lin, Y.8    Fan, D.9    Yang, M.10
  • 120
    • 33745736603 scopus 로고    scopus 로고
    • Multidrug resistance: Retrospect and prospects in anti-cancer drug treatment
    • Pérez-Tomás R (2006) Multidrug resistance: retrospect and prospects in anti-cancer drug treatment. Curr Med Chem 13:1859-1876.
    • (2006) Curr Med Chem , vol.13 , pp. 1859-1876
    • Pérez-Tomás, R.1
  • 122
    • 9644257647 scopus 로고    scopus 로고
    • An MDR-EGFP gene fusion allows for direct cellular localization, function and stability assessment of P-glycoprotein
    • Pétriz J, Gottesman MM, and Aran JM (2004) An MDR-EGFP gene fusion allows for direct cellular localization, function and stability assessment of P-glycoprotein. Curr Drug Deliv 1:43-56.
    • (2004) Curr Drug Deliv , vol.1 , pp. 43-56
    • Pétriz, J.1    Gottesman, M.M.2    Aran, J.M.3
  • 124
    • 0025193531 scopus 로고
    • Photosensitized labeling of a functional multidrug transporter in living drug-resistant tumor cells
    • Raviv Y, Pollard HB, Bruggemann EP, Pastan I, and Gottesman MM (1990) Photosensitized labeling of a functional multidrug transporter in living drug-resistant tumor cells. J Biol Chem 265:3975-3980.
    • (1990) J Biol Chem , vol.265 , pp. 3975-3980
    • Raviv, Y.1    Pollard, H.B.2    Bruggemann, E.P.3    Pastan, I.4    Gottesman, M.M.5
  • 125
    • 0023786746 scopus 로고
    • Stability and covalent modification of P-glycoprotein in multidrug-resistant KB cells
    • Richert ND, Aldwin L, Nitecki D, Gottesman MM, and Pastan I (1988) Stability and covalent modification of P-glycoprotein in multidrug-resistant KB cells. Biochemistry 27:7607-7613.
    • (1988) Biochemistry , vol.27 , pp. 7607-7613
    • Richert, N.D.1    Aldwin, L.2    Nitecki, D.3    Gottesman, M.M.4    Pastan, I.5
  • 126
    • 0031440794 scopus 로고    scopus 로고
    • Molecular mechanisms of endocytosis
    • DOI 10.1016/S0092-8674(00)80461-4
    • Riezman H, Woodman PG, van Meer G, and Marsh M (1997) Molecular mechanisms of endocytosis. Cell 91:731-738. (Pubitemid 28007730)
    • (1997) Cell , vol.91 , Issue.6 , pp. 731-738
    • Riezman, H.1    Woodman, P.G.2    Van Meer, G.3    Marsh, M.4
  • 128
    • 84055213521 scopus 로고    scopus 로고
    • Expression of ATP-binding cassette membrane transporters in rodent and human sertoli cells: Relevance to the permeability of antiretroviral therapy at the blood-testis barrier
    • Robillard KR, Hoque T, and Bendayan R (2012) Expression of ATP-binding cassette membrane transporters in rodent and human sertoli cells: relevance to the permeability of antiretroviral therapy at the blood-testis barrier. J Pharmacol Exp Ther 340:96-108.
    • (2012) J Pharmacol Exp Ther , vol.340 , pp. 96-108
    • Robillard, K.R.1    Hoque, T.2    Bendayan, R.3
  • 129
    • 84890204562 scopus 로고    scopus 로고
    • Cell-derived microparticles: New targets in the therapeutic management of disease
    • Roseblade A, Luk F, Rawling T, Ung A, Grau GE, and Bebawy M (2013) Cell-derived microparticles: new targets in the therapeutic management of disease. J Pharm Pharm Sci 16:238-253.
    • (2013) J Pharm Pharm Sci , vol.16 , pp. 238-253
    • Roseblade, A.1    Luk, F.2    Rawling, T.3    Ung, A.4    Grau, G.E.5    Bebawy, M.6
  • 130
    • 0025780606 scopus 로고
    • Reversal of multidrug resistance in HL-60 cells by verapamil and liposome-encapsulated doxorubicin
    • Sadasivan R, Morgan R, Fabian C, and Stephens R (1991) Reversal of multidrug resistance in HL-60 cells by verapamil and liposome-encapsulated doxorubicin. Cancer Lett 57:165-171.
    • (1991) Cancer Lett , vol.57 , pp. 165-171
    • Sadasivan, R.1    Morgan, R.2    Fabian, C.3    Stephens, R.4
  • 131
    • 0000622931 scopus 로고
    • Photoaffinity labeling of the multidrug-resistance-related P-glycoprotein with photoactive analogs of verapamil
    • Safa AR (1988) Photoaffinity labeling of the multidrug-resistance-related P-glycoprotein with photoactive analogs of verapamil. Proc Natl Acad Sci USA 85:7187-7191.
    • (1988) Proc Natl Acad Sci USA , vol.85 , pp. 7187-7191
    • Safa, A.R.1
  • 133
    • 0025565954 scopus 로고
    • Staurosporine, a potent inhibitor of C-kinase, enhances drug accumulation in multidrug-resistant cells
    • Sato W, Yusa K, Naito M, and Tsuruo T (1990) Staurosporine, a potent inhibitor of C-kinase, enhances drug accumulation in multidrug-resistant cells. Biochem Biophys Res Commun 173:1252-1257.
    • (1990) Biochem Biophys Res Commun , vol.173 , pp. 1252-1257
    • Sato, W.1    Yusa, K.2    Naito, M.3    Tsuruo, T.4
  • 135
    • 84884981171 scopus 로고    scopus 로고
    • Inhibition of Wnt/b-catenin signaling downregulates P-glycoprotein and reverses multi-drug resistance of cholangiocarcinoma
    • Shen D-Y, Zhang W, Zeng X, and Liu C-Q (2013) Inhibition of Wnt/b-catenin signaling downregulates P-glycoprotein and reverses multi-drug resistance of cholangiocarcinoma. Cancer Sci 104: 1303-1308.
    • (2013) Cancer Sci , vol.104 , pp. 1303-1308
    • Shen, D.-Y.1    Zhang, W.2    Zeng, X.3    Liu, C.-Q.4
  • 136
    • 1842830340 scopus 로고    scopus 로고
    • Effect of Ticlopidine on Monocyte-derived Microparticles and Activated Platelet Markers in Diabetes Mellitus
    • DOI 10.1177/107602960401000207
    • Shouzu A, Nomura S, Omoto S, Hayakawa T, Nishikawa M, and Iwasaka T (2004) Effect of ticlopidine on monocyte-derived microparticles and activated platelet markers in diabetes mellitus. Clin Appl Thromb Hemost 10:167-173. (Pubitemid 38490085)
    • (2004) Clinical and Applied Thrombosis/Hemostasis , vol.10 , Issue.2 , pp. 167-173
    • Shouzu, A.1    Nomura, S.2    Omoto, S.3    Hayakawa, T.4    Nishikawa, M.5    Iwasaka, T.6
  • 137
    • 0021922114 scopus 로고
    • Collateral sensitivity to cross-linking agents exhibited by cultured L1210 cells resistant to oxazaphosphorines
    • Sladek NE, Low JE, and Landkamer GJ (1985) Collateral sensitivity to cross-linking agents exhibited by cultured L1210 cells resistant to oxazaphosphorines. Cancer Res 45:625-629. (Pubitemid 15161058)
    • (1985) Cancer Research , vol.45 , Issue.2 , pp. 625-629
    • Sladek, N.E.1    Low, J.E.2    Landkamer, G.J.3
  • 138
    • 0028818853 scopus 로고
    • Circumvention of P-glycoprotein-mediated multiple drug resistance by phosphorylation modulators is independent of protein kinases
    • Smith CD and Zilfou JT (1995) Circumvention of P-glycoprotein-mediated multiple drug resistance by phosphorylation modulators is independent of protein kinases. J Biol Chem 270:28145-28152.
    • (1995) J Biol Chem , vol.270 , pp. 28145-28152
    • Smith, C.D.1    Zilfou, J.T.2
  • 139
    • 0025231578 scopus 로고
    • Characterization of a membrane-associated protein kinase of multidrug-resistant HL60 cells which phosphorylates P-glycoprotein
    • Staats J, Marquardt D, and Center MS (1990) Characterization of a membrane-associated protein kinase of multidrug-resistant HL60 cells which phosphorylates P-glycoprotein. J Biol Chem 265:4084-4090.
    • (1990) J Biol Chem , vol.265 , pp. 4084-4090
    • Staats, J.1    Marquardt, D.2    Center, M.S.3
  • 140
    • 34249679271 scopus 로고    scopus 로고
    • ABC transporters and drug resistance in leukemia: Was P-gp nothing but the first head of the Hydra?
    • DOI 10.1038/sj.leu.2404692, PII 2404692
    • Steinbach D and Legrand O (2007) ABC transporters and drug resistance in leukemia: was P-gp nothing but the first head of the Hydra? Leukemia 21:1172-1176. (Pubitemid 46831804)
    • (2007) Leukemia , vol.21 , Issue.6 , pp. 1172-1176
    • Steinbach, D.1    Legrand, O.2
  • 141
    • 84860480401 scopus 로고    scopus 로고
    • Signal transduction pathways and transcriptional mechanisms of ABCB1/Pgp-mediated multiple drug resistance in human cancer cells
    • Sui H, Fan ZZ, and Li Q (2012) Signal transduction pathways and transcriptional mechanisms of ABCB1/Pgp-mediated multiple drug resistance in human cancer cells. J Int Med Res 40:426-435.
    • (2012) J Int Med Res , vol.40 , pp. 426-435
    • Sui, H.1    Fan, Z.Z.2    Li, Q.3
  • 142
    • 77956544799 scopus 로고    scopus 로고
    • Inhibition of ABCB1 (MDR1) expression by an siRNA nanoparticulate delivery system to overcome drug resistance in osteosarcoma
    • Susa M, Iyer AK, Ryu K, Choy E, Hornicek FJ, Mankin H, Milane L, Amiji MM, and Duan Z (2010) Inhibition of ABCB1 (MDR1) expression by an siRNA nanoparticulate delivery system to overcome drug resistance in osteosarcoma. PLoS ONE 5:e10764.
    • (2010) PLoS ONE , vol.5
    • Susa, M.1    Iyer, A.K.2    Ryu, K.3    Choy, E.4    Hornicek, F.J.5    Mankin, H.6    Milane, L.7    Amiji, M.M.8    Duan, Z.9
  • 143
    • 0035038919 scopus 로고    scopus 로고
    • The orphan nuclear receptor SXR coordinately regulates drug metabolism and efflux
    • DOI 10.1038/87912
    • Synold TW, Dussault I, and Forman BM (2001) The orphan nuclear receptor SXR coordinately regulates drug metabolism and efflux. Nat Med 7:584-590. (Pubitemid 32448326)
    • (2001) Nature Medicine , vol.7 , Issue.5 , pp. 584-590
    • Synold, T.W.1    Dussault, I.2    Forman, B.M.3
  • 144
    • 0001532292 scopus 로고
    • Genetic studies on microbial cross resistance to toxic agents. I. Cross resistance of Escherichia coli to fifteen antibiotics
    • Szybalski W and Bryson V (1952) Genetic studies on microbial cross resistance to toxic agents. I. Cross resistance of Escherichia coli to fifteen antibiotics. J Bacteriol 64:489-499.
    • (1952) J Bacteriol , vol.64 , pp. 489-499
    • Szybalski, W.1    Bryson, V.2
  • 145
    • 84895874955 scopus 로고    scopus 로고
    • PEITC reverse multi-drug resistance of human gastric cancer SGC7901/DDP cell line
    • DOI: 10.1002/cbin.10169
    • Tang T, Song X, Liu YF, and Wang WY (2013) PEITC reverse multi-drug resistance of human gastric cancer SGC7901/DDP cell line. Cell Biol Int DOI: 10.1002/cbin.10169.
    • (2013) Cell Biol Int
    • Tang, T.1    Song, X.2    Liu, Y.F.3    Wang, W.Y.4
  • 147
    • 0024794421 scopus 로고
    • Modulation of multidrug resistance in Chinese hamster cells by liposome-encapsulated doxorubicin
    • Thierry AR, Jorgensen TJ, Forst D, Belli JA, Dritschilo A, and Rahman A (1989) Modulation of multidrug resistance in Chinese hamster cells by liposome-encapsulated doxorubicin. Cancer Commun 1:311-316.
    • (1989) Cancer Commun , vol.1 , pp. 311-316
    • Thierry, A.R.1    Jorgensen, T.J.2    Forst, D.3    Belli, J.A.4    Dritschilo, A.5    Rahman, A.6
  • 148
    • 0020549246 scopus 로고
    • Circumvention of vincristine and adriamycin resistance in vitro and in vivo by calcium influx blockers
    • Tsuruo T, Iida H, Nojiri M, Tsukagoshi S, and Sakurai Y (1983) Circumvention of vincristine and Adriamycin resistance in vitro and in vivo by calcium influx blockers. Cancer Res 43:2905-2910. (Pubitemid 13100565)
    • (1983) Cancer Research , vol.43 , Issue.6 , pp. 2905-2910
    • Tsuruo, T.1    Iida, H.2    Nojiri, M.3
  • 149
    • 0020426820 scopus 로고
    • Increased accumulation of vincristine and Adriamycin in drug-resistant P388 tumor cells following incubation with calcium antagonists and calmodulin inhibitors
    • Tsuruo T, Iida H, Tsukagoshi S, and Sakurai Y (1982) Increased accumulation of vincristine and adriamycin in drug-resistant P388 tumor cells following incubation with calcium antagonists and calmodulin inhibitors. Cancer Res 42:4730-4733. (Pubitemid 13205981)
    • (1982) Cancer Research , vol.42 , Issue.11 , pp. 4730-4733
    • Tsuruo, T.1    Iida, H.2    Tsukagoshi, S.3    Sakurai, Y.4
  • 150
    • 0029028792 scopus 로고
    • Overlapping substrate specificities and tissue distribution of cytochrome P450 3A and P-glycoprotein: Implications for drug delivery and activity in cancer chemotherapy
    • Wacher VJ, Wu CY, and Benet LZ (1995) Overlapping substrate specificities and tissue distribution of cytochrome P450 3A and P-glycoprotein: implications for drug delivery and activity in cancer chemotherapy. Mol Carcinog 13:129-134.
    • (1995) Mol Carcinog , vol.13 , pp. 129-134
    • Wacher, V.J.1    Wu, C.Y.2    Benet, L.Z.3
  • 151
    • 84878237899 scopus 로고    scopus 로고
    • Dioscin restores the activity of the anticancer agent adriamycin in multidrug-resistant human leukemia K562/adriamycin cells by down-regulating MDR1 via a mechanism involving NF-κB signaling inhibition
    • Wang L, Meng Q, Wang C, Liu Q, Peng J, Huo X, Sun H, Ma X, and Liu K (2013) Dioscin restores the activity of the anticancer agent adriamycin in multidrug-resistant human leukemia K562/adriamycin cells by down-regulating MDR1 via a mechanism involving NF-κB signaling inhibition. J Nat Prod 76:909-914.
    • (2013) J Nat Prod , vol.76 , pp. 909-914
    • Wang, L.1    Meng, Q.2    Wang, C.3    Liu, Q.4    Peng, J.5    Huo, X.6    Sun, H.7    Ma, X.8    Liu, K.9
  • 152
    • 77958110674 scopus 로고    scopus 로고
    • Interaction of tyrosine kinase inhibitors with the MDR- related ABC transporter proteins
    • Wang XK and Fu LW (2010) Interaction of tyrosine kinase inhibitors with the MDR- related ABC transporter proteins. Curr Drug Metab 11:618-628.
    • (2010) Curr Drug Metab , vol.11 , pp. 618-628
    • Wang, X.K.1    Fu, L.W.2
  • 153
    • 79959742759 scopus 로고    scopus 로고
    • P-glycoprotein substrate models using support vector machines based on a comprehensive data set
    • Wang Z, Chen Y, Liang H, Bender A, Glen RC, and Yan A (2011) P-glycoprotein substrate models using support vector machines based on a comprehensive data set. J Chem Inf Model 51:1447-1456.
    • (2011) J Chem Inf Model , vol.51 , pp. 1447-1456
    • Wang, Z.1    Chen, Y.2    Liang, H.3    Bender, A.4    Glen, R.C.5    Yan, A.6
  • 154
    • 10344256151 scopus 로고    scopus 로고
    • Regulation of the multidrug resistance transporter P-glycoprotein in multicellular prostate tumor spheroids by hyperthermia and reactive oxygen species
    • DOI 10.1002/ijc.20596
    • Wartenberg M, Gronczynska S, Bekhite MM, Saric T, Niedermeier W, Hescheler J, and Sauer H (2005) Regulation of the multidrug resistance transporter P-glycoprotein in multicellular prostate tumor spheroids by hyperthermia and reactive oxygen species. Int J Cancer 113:229-240. (Pubitemid 39628313)
    • (2005) International Journal of Cancer , vol.113 , Issue.2 , pp. 229-240
    • Wartenberg, M.1    Gronczynska, S.2    Bekhite, M.M.3    Saric, T.4    Niedermeier, W.5    Hescheler, J.6    Sauer, H.7
  • 155
    • 25644448837 scopus 로고    scopus 로고
    • Inhibition of endothelial activation: A new way to treat cerebral
    • Wassmer SC, Cianciolo GJ, Combes V, and Grau GE (2005) Inhibition of endothelial activation: a new way to treat cerebral malaria? PLoS Med 2:e245.
    • (2005) PLoS Med , vol.2
    • Wassmer, S.C.1    Cianciolo, G.J.2    Combes, V.3    Grau, G.E.4
  • 156
    • 0343067072 scopus 로고    scopus 로고
    • Endosomes, lysosomes: Their implication in gene transfer
    • DOI 10.1016/S0169-409X(99)00066-6, PII S0169409X99000666
    • Wattiaux R, Laurent N, Wattiaux-De Coninck S, and Jadot M (2000) Endosomes, lysosomes: their implication in gene transfer. Adv Drug Deliv Rev 41:201-208. (Pubitemid 30122959)
    • (2000) Advanced Drug Delivery Reviews , vol.41 , Issue.2 , pp. 201-208
    • Wattiaux, R.1    Laurent, N.2    Wattiaux-De, C.S.3    Jadot, M.4
  • 157
    • 84876297950 scopus 로고    scopus 로고
    • Potential of the novel antiretroviral drug rilpivirine to modulate the expression and function of drug transporters and drug-metabolising enzymes in vitro
    • Weiss J and Haefeli WE (2013) Potential of the novel antiretroviral drug rilpivirine to modulate the expression and function of drug transporters and drug-metabolising enzymes in vitro. Int J Antimicrob Agents 41:484-487.
    • (2013) Int J Antimicrob Agents , vol.41 , pp. 484-487
    • Weiss, J.1    Haefeli, W.E.2
  • 159
    • 84880383587 scopus 로고    scopus 로고
    • Parthenolide reverses doxorubicin resistance in human lung carcinoma A549 cells by attenuating NF-κB activation and HSP70 up-regulation
    • Xin Y, Yin F, Qi S, Shen L, Xu Y, Luo L, Lan L, and Yin Z (2013) Parthenolide reverses doxorubicin resistance in human lung carcinoma A549 cells by attenuating NF-κB activation and HSP70 up-regulation. Toxicol Lett 221:73-82.
    • (2013) Toxicol Lett , vol.221 , pp. 73-82
    • Xin, Y.1    Yin, F.2    Qi, S.3    Shen, L.4    Xu, Y.5    Luo, L.6    Lan, L.7    Yin, Z.8
  • 160
    • 23344450788 scopus 로고    scopus 로고
    • Induction of phase I, II and III drug metabolism/transport by xenobiotics
    • Xu C, Li CY, and Kong AN (2005) Induction of phase I, II and III drug metabolism/transport by xenobiotics. Arch Pharm Res 28:249-268. (Pubitemid 44698742)
    • (2005) Archives of Pharmacal Research , vol.28 , Issue.3 , pp. 249-268
    • Xu, C.1    Li, C.Y.-T.2    Kong, A.-N.T.3
  • 161
    • 84859255783 scopus 로고    scopus 로고
    • Investigation of folate-conjugated fluorescent silica nanoparticles for targeting delivery to folate receptor-positive tumors and their internalization mechanism
    • Yang H, Lou C, Xu M, Wu C, Miyoshi H, and Liu Y (2011) Investigation of folate-conjugated fluorescent silica nanoparticles for targeting delivery to folate receptor-positive tumors and their internalization mechanism. Int J Nanomedicine 6:2023-2032.
    • (2011) Int J Nanomedicine , vol.6 , pp. 2023-2032
    • Yang, H.1    Lou, C.2    Xu, M.3    Wu, C.4    Miyoshi, H.5    Liu, Y.6
  • 162
    • 0029683163 scopus 로고    scopus 로고
    • Interaction of P-glycoprotein with protein kinase C in human multidrug resistant carcinoma cells
    • Yang JM, Chin KV, and Hait WN (1996) Interaction of P-glycoprotein with protein kinase C in human multidrug resistant carcinoma cells. Cancer Res 56:3490-3494.
    • (1996) Cancer Res , vol.56 , pp. 3490-3494
    • Yang, J.M.1    Chin, K.V.2    Hait, W.N.3
  • 164
    • 0033328139 scopus 로고    scopus 로고
    • The contribution of P-glycoprotein to pharmacokinetic drug-drug interactions
    • Yu DK (1999) The contribution of P-glycoprotein to pharmacokinetic drug-drug interactions. J Clin Pharmacol 39:1203-1211.
    • (1999) J Clin Pharmacol , vol.39 , pp. 1203-1211
    • Yu, D.K.1
  • 165
    • 0034086333 scopus 로고    scopus 로고
    • Cell-cycle-dependent turnover of P-glycoprotein in multidrug-resistant cells
    • DOI 10.1002/(SICI)1097-4652(200007)184:1<17::AID-J
    • Zhang W and Ling V (2000) Cell-cycle-dependent turnover of P-glycoprotein in multidrug-resistant cells. J Cell Physiol 184:17-26. (Pubitemid 30349624)
    • (2000) Journal of Cellular Physiology , vol.184 , Issue.1 , pp. 17-26
    • Zhang, W.1    Ling, V.2
  • 166
    • 84881605979 scopus 로고    scopus 로고
    • Grape seed procyanidin reversal of p-glycoprotein associated multi-drug resistance via down-regulation of NF-κB and MAPK/ERK mediated YB-1 activity in A2780/T cells
    • Zhao BX, Sun YB, Wang SQ, Duan L, Huo QL, Ren F, and Li GF (2013) Grape seed procyanidin reversal of p-glycoprotein associated multi-drug resistance via down-regulation of NF-κB and MAPK/ERK mediated YB-1 activity in A2780/T cells. PLoS ONE 8:e71071.
    • (2013) PLoS ONE , vol.8
    • Zhao, B.X.1    Sun, Y.B.2    Wang, S.Q.3    Duan, L.4    Huo, Q.L.5    Ren, F.6    Li, G.F.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.