Characterization of phosphorylation-defective mutants of human P-glycoprotein expressed in mammalian cells

Journal of Biological Chemistry

Volumn 271, Issue 3, 1996, Pages 1708-1716

  Germann, Ursula A ^a,b   Chambers, Timothy C ^c   Ambudkar, Suresh V ^a,d   Licht, Thomas ^a   Cardarelli, Carol O ^a   Pastan, Ira ^a   Gottesman, Michael M ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

^b VERTEX PHARMACEUTICALS   (United States)

^c UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES   (United States)

^d JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE; ASPARTIC ACID; AZIDOPINE; COLCHICINE; CYCLIC AMP DEPENDENT PROTEIN KINASE; DOXORUBICIN; GLYCOPROTEIN P; MUTANT PROTEIN; PHOSPHATE; PHOSPHORUS 32; PROTEIN KINASE C; SERINE; VINBLASTINE; VINCRISTINE;

AMINO ACID SUBSTITUTION; ANIMAL CELL; ARTICLE; CARCINOMA CELL; CELL STRAIN 3T3; CELL SURVIVAL; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG SENSITIVITY; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; MAMMAL CELL; MOUSE; MULTIDRUG RESISTANCE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION;

3T3 CELLS; ALANINE; AMINO ACID SEQUENCE; ANIMALS; ASPARTIC ACID; BASE SEQUENCE; CELL MEMBRANE; DNA MUTATIONAL ANALYSIS; DRUG RESISTANCE, MULTIPLE; GENE EXPRESSION; HUMANS; MAMMALS; MICE; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; OLIGODEOXYRIBONUCLEOTIDES; P-GLYCOPROTEIN; PHOSPHORYLATION; POINT MUTATION; RECOMBINANT PROTEINS; RESTRICTION MAPPING; SERINE; TRANSFECTION; VINCRISTINE;

ANIMALIA; MAMMALIA;

EID: 0030067789     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.271.3.1708     Document Type: Article

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