Poly(styrene oxide)-poly(ethylene oxide) block copolymers: From "classical" chemotherapeutic nanocarriers to active cell-response inducers

Journal of Controlled Release

Volumn 167, Issue 1, 2013, Pages 68-75

  Cambon A ^a   Rey Rico, A ^b   Barbosa, S ^a   Soltero, J F A ^c   Yeates, S G ^d   Brea, J ^e   Loza, M I ^e   Alvarez Lorenzo, C ^b,e   Concheiro, A ^b,e   Taboada, P ^a   Mosquera, V ^a  

^a Grupo de Física de Coloides y Polímeros   (Spain)

^b Campus Universitario   (Spain)

^c UNIVERSITY OF GUADALAJARA   (Mexico)

^d UNIVERSITY OF MANCHESTER   (United Kingdom)

^e UNIVERSITY OF SANTIAGO DE COMPOSTELA   (Spain)

Author keywords

Cytotoxicity; Doxorubicin; Drug delivery; Multidrug resistant cells; p glycoprotein efflux pump; Polymeric micelles

Indexed keywords

BIOLOGICAL RESPONSE MODIFIERS; CLINICAL EVALUATION; DOXORUBICIN; EFFLUX PUMPS; ENTRAPMENT EFFICIENCY; MULTIDRUG RESISTANTS; POLY(STYRENE OXIDE); POLYMERIC MICELLE;

BLOCK COPOLYMERS; CELLS; CHEMOTHERAPY; CYTOTOXICITY; DRUG DELIVERY; GLYCOPROTEINS; LOADING; MICELLES; PHARMACODYNAMICS; POLYETHYLENE OXIDES; POLYMERS; SOLUBILITY; STYRENE;

CELL CULTURE;

ADENOSINE TRIPHOSPHATASE; COPOLYMER; DOXORUBICIN; GLYCOPROTEIN P INHIBITOR; NANOCARRIER; POLY(STYRENE OXIDE); STYRENE OXIDE; UNCLASSIFIED DRUG;

ARTICLE; CANCER RESISTANCE; CONTROLLED STUDY; DRUG ACCUMULATION; DRUG CYTOTOXICITY; DRUG DELIVERY SYSTEM; DRUG DISTRIBUTION; DRUG EFFICACY; DRUG SOLUBILITY; DRUG STABILITY; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; MICELLE; OVARY CANCER; PH; PHYSICAL CHEMISTRY; POLYMERIZATION; PRIORITY JOURNAL; SOLUBILIZATION;

ADENOSINE TRIPHOSPHATASES; ANTIBIOTICS, ANTINEOPLASTIC; CELL LINE, TUMOR; DOXORUBICIN; DRUG CARRIERS; DRUG RESISTANCE, NEOPLASM; DRUG STABILITY; HUMANS; MICELLES; NANOPARTICLES; P-GLYCOPROTEIN; POLYETHYLENE GLYCOLS; POLYSTYRENES;

EID: 84873713319     PISSN: 01683659     EISSN: 18734995     Source Type: Journal    
DOI: 10.1016/j.jconrel.2013.01.010     Document Type: Article

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