Microparticles mediate MRP1 intercellular transfer and the re-templating of intrinsic resistance pathways

Pharmacological Research

Volumn 76, Issue , 2013, Pages 77-83

  Lu, Jamie F ^a   Luk, Frederick ^a   Gong, Joyce ^a,b   Jaiswal, Ritu ^a,b   Grau, Georges E R ^b   Bebawy, Mary ^a  

^a UNIVERSITY OF TECHNOLOGY SYDNEY   (Australia)

^b UNIVERSITY OF SYDNEY   (Australia)

Author keywords

Intercellular transfer; Microparticles; Multidrug resistance; Multidrug Resistance Associated Protein 1; P glycoprotein; Re templating; Trait dominance

Indexed keywords

MULTIDRUG RESISTANCE PROTEIN 1;

ACUTE LYMPHOBLASTIC LEUKEMIA; ARTICLE; CELL POPULATION; CELL TRANSFER; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INHIBITION; HUMAN; HUMAN CELL; LEUKEMIA CELL; MEMBRANE MICROPARTICLE; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN TARGETING;

A.U.; ARBITRARY UNITS; CT; CYCLE THRESHOLD; FCM; FLOW CYTOMETRY; INTERCELLULAR TRANSFER; MDR; MEAN FLUORESCENCE INTENSITY; MFI; MICROPARTICLES; MPS; MRP1; MULTIDRUG RESISTANCE; MULTIDRUG RESISTANCE-ASSOCIATED PROTEIN 1; P-GLYCOPROTEIN; P-GP; PBC; PROBENECID; QRT-PCR; QUANTITATIVE REAL-TIME PCR; RE-TEMPLATING; TRAIT DOMINANCE;

ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; CELL-DERIVED MICROPARTICLES; DRUG RESISTANCE, MULTIPLE; DRUG RESISTANCE, NEOPLASM; HUMANS; MULTIDRUG RESISTANCE-ASSOCIATED PROTEINS; PRECURSOR CELL LYMPHOBLASTIC LEUKEMIA-LYMPHOMA; SIGNAL TRANSDUCTION;

EID: 84883095688     PISSN: 10436618     EISSN: 10961186     Source Type: Journal    
DOI: 10.1016/j.phrs.2013.07.009     Document Type: Article

References (40)

1. M. Bebawy, V. Combes, E. Lee, R. Jaiswal, J. Gong, and A. Bonhoure Membrane microparticles mediate transfer of p-glycoprotein to drug sensitive cancer cells Leukemia 23 2009 1643 1649
2. D.B. Longley, and P.G. Johnston Molecular mechanisms of drug resistance J Pathol 205 2005 275 292 (Pubitemid 40227997)
3. G. Morgan, R. Ward, and M. Barton The contribution of cytotoxic chemotherapy to 5-year survival in adult malignancies Clin Oncol 16 2004 549 560 (Pubitemid 39517664)
4. M. Bebawy, M.B. Morris, and B.D. Roufogalis Selective modulation of p-glycoprotein-mediated drug resistance Br J Cancer 85 2001 1998 2003 (Pubitemid 34775339)
5. J. Gong, R. Jaiswal, J.M. Mathys, V. Combes, G.E.R. Grau, and M. Bebawy Microparticles and their emerging role in cancer multidrug resistance Cancer Treat Rev 38 2012 226 234
6. M. Munoz, M. Henderson, M. Haber, and M. Norris Role of the mrp1/abcc1 multidrug transporter protein in cancer IUBMB Life 59 2007 752 757 (Pubitemid 351412076)
7. R.W. Robey, K.K.K. To, O. Polgar, M. Dohse, P. Fetsch, and M. Dean Abcg2. A perspective Adv Drug Deliv Rev 61 2009 3 13
8. L. Schmitt, and R. Tampé Structure and mechanism of abc transporters Curr Opin Struct Biol 12 2002 754 760 (Pubitemid 36009492)
9. A. van Helvoort, A.J. Smith, H. Sprong, I. Fritzsche, A.H. Schinkel, and P. Borst Mdr1 p-glycoprotein is a lipid translocase of broad specificity, while mdr3 p-glycoprotein specifically translocates phosphatidylcholine Cell 87 1996 507 517 (Pubitemid 26374324)
10. A. Konieczna, B. Erdösová, R. Lichnovská, M. Jandl, K. Čížková, and J. Ehrmann Differential expression of abc transporters (mdr1, mrp1, bcrp) in developing human embryos J Mol Histol 42 2011 567 574
11. C. Ziemann, A. Bürkle, G.F. Kahl, and K.I. Hirsch-Ernst Reactive oxygen species participate in mdr1b mrna and p-glycoprotein overexpression in primary rat hepatocyte cultures Carcinogenesis 20 1999 407 414 (Pubitemid 29112627)
12. R.A. Davey, T.J. Longhurst, M.W. Davey, L. Belov, R.M. Harvie, and D. Hancox Drug resistance mechanisms and mrp expression in response to epirubicin treatment in a human leukaemia cell line Leuk Res 19 1995 275 282
13. F. Di Nicolantonio, S. Mercer, L. Knight, F. Gabriel, P. Whitehouse, and S. Sharma Cancer cell adaptation to chemotherapy BMC Cancer 5 2005 1 16
14. X.F. Hu, A. Slater, D.M. Wall, P. Kantharidis, J.D. Parkin, and A. Cowman Rapid up-regulation of mdr1 expression by anthracyclines in a classical multidrug-resistant cell line Br J Cancer 71 1995 931 936
15. D. Schrenk, P.R. Baus, N. Ermel, C. Klein, B. Vorderstemann, and H-M. Kauffmann Up-regulation of transporters of the mrp family by drugs and toxins Toxicol Lett 120 2001 51 57 (Pubitemid 32375070)
16. C. Calatozzolo, M. Gelati, E. Ciusani, F.L. Sciacca, B. Pollo, and L. Cajola Expression of drug resistance proteins pgp, mrp1, mrp3, mrp5 and gst-π in human glioma J Neurooncol 74 2005 113 121 (Pubitemid 41478906)
17. O. Morel, N. Morel, J-M. Freyssinet, and F. Toti Platelet microparticles and vascular cells interactions: a checkpoint between the haemostatic and thrombotic responses Platelets 19 2008 9 23 (Pubitemid 351171554)
18. J.L. Yu, and J.W. Rak Shedding of tissue factor (tf)-containing microparticles rather than alternatively spliced tf is the main source of tf activity released from human cancer cells J Thromb Haemost 2 2004 2065 2067 (Pubitemid 40192770)
19. A.P. Owens, and N. Mackman Microparticles in hemostasis and thrombosis Circ Res 108 2011 1284 1297
20. R. Jaiswal, J. Gong, S. Sambasivam, V. Combes, J.-M. Mathys, and R. Davey Microparticle-associated nucleic acids mediate trait dominance in cancer FASEB J 2011
21. R. Jaiswal, F. Luk, J. Gong, J.M. Mathys, G.E. Grau, and M. Bebawy Microparticle conferred microrna profiles - implications in the transfer and dominance of cancer traits Mol Cancer 11 2012 37
22. J.H.W. Distler, L.C. Huber, S. Gay, O. Distler, and D.S. Pisetsky Microparticles as mediators of cellular cross-talk in inflammatory disease Autoimmunity 39 2006 683 690 (Pubitemid 44964371)
23. T.A. Whale, H.L. Wilson, S.K. Tikoo, L.A. Babiuk, and P.J. Griebel Passively acquired membrane proteins alter the functional capacity of bovine polymorphonuclear cells J Leukoc Biol 80 2006 481 491 (Pubitemid 44835781)
24. R. Jaiswal, F. Luk, P.V. Dalla, G.E.R. Grau, and M. Bebawy Breast cancer-derived microparticles display tissue selectivity in the transfer of resistance proteins to cells PLoS ONE 8 2013 e61515
25. G.E. Foley, H. Lazarus, S. Farber, B.G. Uzman, B.A. Boone, and R.E. McCarthy Continuous culture of human lymphoblasts from peripheral blood of a child with acute leukemia Cancer 18 1965 522 529
26. M. Bebawy, M.B. Morris, and B.D. Roufogalis A continuous fluorescence assay for the study of p-glycoprotein-mediated drug efflux using inside-out membrane vesicles Anal Biochem 268 1999 270 277 (Pubitemid 29147142)
27. A.L. Dogan, O. Legrand, A.-M. Faussat, J.-Y. Perrot, and J.-P. Marie Evaluation and comparison of mrp1 activity with three fluorescent dyes and three modulators in leukemic cell lines Leuk Res 28 2004 619 622 (Pubitemid 38543199)
28. Y. Donmez, L. Akhmetova, O.D. Iseri, M.D. Kars, and U. Gunduz Effect of mdr modulators verapamil and promethazine on gene expression levels of mdr1 and mrp1 in doxorubicin-resistant mcf-7 cells Cancer Chemother Pharmacol 67 2011 823 828
29. D.P. Olson, B.J. Taylor, and S.P. Ivy Detection of mrp functional activity: calcein am but not bcecf am as a multidrug resistance-related protein (mrp1) substrate Cytometry 46 2001 105 113 (Pubitemid 32423461)
30. Z. Holló, L. Homolya, C.W. Davis, and B. Sarkadi Calcein accumulation as a fluorometric functional assay of the multidrug transporter Biochim Biophys Acta (BBA) - Biomembr 1191 1994 384 388 (Pubitemid 24183562)
31. D. Faille, F. El-Assaad, A.J. Mitchell, M-C. Alessi, G. Chimini, and T. Fusai Endocytosis and intracellular processing of platelet microparticles by brain endothelial cells J Cell Mol Med 16 2012 1731 1738
32. E. Bakos, R. Evers, G. Calenda, G.E. Tusnady, G. Szakacs, and A. Varadi Characterization of the amino-terminal regions in the human multidrug resistance protein (mrp1) J Cell Sci 113 2000 4451 4461 (Pubitemid 32117906)
33. E.I. Stolarczyk, C.J. Reiling, K.A. Pickin, R. Coppage, M.R. Knecht, and C.M. Paumi Casein kinase 2α (ck2α) regulates multidrug resistance associated protein (mrp1) function via phosphorylation of thr249 Mol Pharmacol 2012
34. J. Renes, E.G.E. De Vries, E.F. Nienhuis, P.L.M. Jansen, and M. Müller Atp- and glutathione-dependent transport of chemotherapeutic drugs by the multidrug resistance protein mrp1 Br J Pharmacol 126 1999 681 688 (Pubitemid 29087847)
35. O. Legrand, G. Simonin, A. Beauchamp-Nicoud, R. Zittoun, and J-P. Marie Simultaneous activity of mrp1 and pgp is correlated with in vitro resistance to daunorubicin and with in vivo resistance in adult acute myeloid leukemia Blood 94 1999 1046 1056 (Pubitemid 29361837)
36. S.F. Mause, and C. Weber Microparticles Circ Res 107 2010 1047 1057
37. O. Kovalchuk, J. Filkowski, J. Meservy, Y. Ilnytskyy, V.P. Tryndyak, and V.F. Chekhun Involvement of microrna-451 in resistance of the mcf-7 breast cancer cells to chemotherapeutic drug doxorubicin Mol Cancer Ther 7 2008 2152 2159
38. H. Zhu, H. Wu, X. Liu, B.R. Evans, D.J. Medina, and C.-G. Liu Role of microrna mir-27a and mir-451 in the regulation of mdr1/p-glycoprotein expression in human cancer cells Biochem Pharmacol 76 2008 582 588
39. H. Zhang, Z. Chen, X. Wang, Z. Huang, Z. He, and Y. Chen Long non-coding rna: a new player in cancer J Hematol Oncol 6 2013 37
40. Y. Yang, H. Li, S. Hou, B. Hu, J. Liu, and J. Wang The noncoding rna expression profile and the effect of lncrna ak126698 on cisplatin resistance in non-small-cell lung cancer cell PLoS ONE 8 2013 e65309