Parthenolide reverses doxorubicin resistance in human lung carcinoma A549 cells by attenuating NF-κB activation and HSP70 up-regulation

Toxicology Letters

Volumn 221, Issue 2, 2013, Pages 73-82

  Xin, Yinqiang ^a   Yin, Fei ^a   Qi, Shimei ^a   Shen, Lei ^a   Xu, Yimiao ^a   Luo, Lan ^b   Lan, Lei ^a   Yin, Zhimin ^a  

^a NANJING NORMAL UNIVERSITY   (China)

^b NANJING UNIVERSITY   (China)

Author keywords

Doxorubicin resistance; HSP70; NF B; P glycoprotein; Parthenolide

Indexed keywords

DOXORUBICIN; HEAT SHOCK PROTEIN 70; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MULTIDRUG RESISTANCE PROTEIN; PARTHENOLIDE; SESQUITERPENE;

APOPTOSIS; ARTICLE; CARCINOMA CELL; CELL VIABILITY; CONFOCAL LASER MICROSCOPY; CONTROLLED STUDY; HUMAN; HUMAN CELL; LUNG CARCINOMA; NICK END LABELING; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA INTERFERENCE; UPREGULATION; WESTERN BLOTTING; CELL SURVIVAL; CONFOCAL MICROSCOPY; DRUG EFFECTS; DRUG RESISTANCE; GENETICS; LUNG TUMOR; METABOLISM; SIGNAL TRANSDUCTION; TUMOR CELL LINE;

APOPTOSIS; CELL LINE, TUMOR; CELL SURVIVAL; DOXORUBICIN; DRUG RESISTANCE, NEOPLASM; HSP70 HEAT-SHOCK PROTEINS; HUMANS; IN SITU NICK-END LABELING; LUNG NEOPLASMS; MICROSCOPY, CONFOCAL; NF-KAPPA B; P-GLYCOPROTEIN; SESQUITERPENES; SIGNAL TRANSDUCTION; UP-REGULATION;

EID: 84880383587     PISSN: 03784274     EISSN: 18793169     Source Type: Journal    
DOI: 10.1016/j.toxlet.2013.06.215     Document Type: Article

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