TCDD decreases ATP levels and increases reactive oxygen production through changes in mitochondrial F0F1-ATP synthase and ubiquinone

Toxicology and Applied Pharmacology

Volumn 217, Issue 3, 2006, Pages 363-374

  Shertzer, Howard G ^a   Genter, Mary Beth ^a   Shen, Dongxiao ^a   Nebert, Daniel W ^a   Chen, Ying ^a   Dalton, Timothy P ^a  

^a UNIVERSITY OF CINCINNATI MEDICAL CENTER   (United States)

Author keywords

ATP; Complex 3; Energy coupling; F0F1 ATP synthase; Mitochondria; Mouse liver; Oxidative stress; Reactive oxygen; Redox cycling; Respiration; TCDD; Ubiquinone; UCP2

Indexed keywords

2,3,7,8 TETRACHLORODIBENZO PARA DIOXIN; ADENOSINE TRIPHOSPHATE; GLUTATHIONE; PROTON TRANSPORTING ADENOSINE TRIPHOSPHATE SYNTHASE; REACTIVE OXYGEN METABOLITE; SUCCINATE DEHYDROGENASE; UBIQUINOL CYTOCHROME C REDUCTASE; UBIQUINONE;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BREATHING RATE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME BLOOD LEVEL; ENZYME RELEASE; ENZYME SYNTHESIS; HYDROLYSIS; LIVER; MALE; MEMBRANE POTENTIAL; MITOCHONDRION; MOUSE; NONHUMAN; OXIDATION REDUCTION REACTION; RESPIRATION CONTROL; TISSUE LEVEL;

ADENOSINE TRIPHOSPHATE; ANIMALS; ELECTRON TRANSPORT COMPLEX III; ENVIRONMENTAL POLLUTANTS; LIVER; MALE; MICE; MICE, INBRED C57BL; MITOCHONDRIA, LIVER; OXIDOREDUCTASES; PROTON-TRANSLOCATING ATPASES; REACTIVE OXYGEN SPECIES; TETRACHLORODIBENZODIOXIN; UBIQUINONE;

EID: 33845227061     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2006.09.014     Document Type: Article

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