Unfolded protein response signaling by transcription factor XBP-1 regulates ADAM10 and is affected in Alzheimer's disease

FASEB Journal

Volumn 28, Issue 2, 2014, Pages 978-997

  Reinhardt, Sven ^a   Schuck, Florian ^a   Grösgen, Sven ^b   Riemenschneider, Matthias ^b   Hartmann, Tobias ^b   Postina, Rolf ^a   Grimm, Marcus ^b   Endres, Kristina ^a  

^a JOHANNES GUTENBERG UNIVERSITY   (Germany)

^b SAARLAND UNIVERSITY   (Germany)

Author keywords

APP processing; ER stress; Insulin signaling; Stress response; secretase

Indexed keywords

ADAM10 ENDOPEPTIDASE; ALPHA SECRETASE; INSULIN; MESSENGER RNA; X BOX BINDING PROTEIN 1; ADAM PROTEIN; ADAM10 PROTEIN, HUMAN; ASPARTIC PROTEINASE; BACE1 PROTEIN, HUMAN; DNA BINDING PROTEIN; MEMBRANE PROTEIN; REGULATORY FACTOR X TRANSCRIPTION FACTORS; SECRETASE; TRANSCRIPTION FACTOR;

ADULT; ALZHEIMER DISEASE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN TISSUE; CONSENSUS SEQUENCE; CONTROLLED STUDY; DELETION MUTANT; ENDOPLASMIC RETICULUM STRESS; ENZYME ACTIVITY; EXPRESSION VECTOR; GEL MOBILITY SHIFT ASSAY; GENE EXPRESSION; GENETIC VARIABILITY; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; MOUSE; NEUROBLASTOMA CELL LINE; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN ANALYSIS; PROTEIN DNA BINDING; PROTEIN EXPRESSION; PROTEIN METABOLISM; PROTEIN SECONDARY STRUCTURE; SIGNAL TRANSDUCTION; TRANSCRIPTION INITIATION; TRANSGENIC MOUSE; TRANSLATION INITIATION; UNFOLDED PROTEIN RESPONSE; ANIMAL; APP PROCESSING; ENZYME LINKED IMMUNOSORBENT ASSAY; GENETICS; INSULIN SIGNALING; METABOLISM; PHYSIOLOGY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STRESS; TUMOR CELL LINE; Α-SECRETASE;

APP PROCESSING; ER STRESS; INSULIN SIGNALING; STRESS RESPONSE; Α-SECRETASE;

ADAM PROTEINS; ALZHEIMER DISEASE; AMYLOID PRECURSOR PROTEIN SECRETASES; ANIMALS; ASPARTIC ACID ENDOPEPTIDASES; CELL LINE, TUMOR; DNA-BINDING PROTEINS; ENZYME-LINKED IMMUNOSORBENT ASSAY; HUMANS; MEMBRANE PROTEINS; MICE; PROMOTER REGIONS, GENETIC; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTORS; UNFOLDED PROTEIN RESPONSE;

EID: 84895795538     PISSN: 08926638     EISSN: 15306860     Source Type: Journal    
DOI: 10.1096/fj.13-234864     Document Type: Article

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