메뉴 건너뛰기




Volumn 81, Issue 5, 2014, Pages 1084-1096

Distinct functional and pharmacological properties of triheteromeric GluN1/GluN2A/GluN2B NMDA receptors

Author keywords

[No Author keywords available]

Indexed keywords

GLUTAMATE RECEPTOR 1; GLUTAMATE RECEPTOR 2; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; PROTEIN GLUN2A; PROTEIN GLUN2B; UNCLASSIFIED DRUG; GLUTAMIC ACID; IFENPRODIL; N METHYL DEXTRO ASPARTIC ACID RECEPTOR 1; N METHYL DEXTRO ASPARTIC ACID RECEPTOR 2A; N METHYL DEXTRO ASPARTIC ACID RECEPTOR 2B; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT; RECOMBINANT PROTEIN; TCN 201; TRAXOPRODIL; ZINC ION;

EID: 84895480210     PISSN: 08966273     EISSN: 10974199     Source Type: Journal    
DOI: 10.1016/j.neuron.2014.01.035     Document Type: Article
Times cited : (227)

References (61)
  • 1
    • 34547652875 scopus 로고    scopus 로고
    • NMDA di-heteromeric receptor populations and associated proteins in rat hippocampus
    • Al-Hallaq R.A., Conrads T.P., Veenstra T.D., Wenthold R.J. NMDA di-heteromeric receptor populations and associated proteins in rat hippocampus. J. Neurosci. 2007, 27:8334-8343.
    • (2007) J. Neurosci. , vol.27 , pp. 8334-8343
    • Al-Hallaq, R.A.1    Conrads, T.P.2    Veenstra, T.D.3    Wenthold, R.J.4
  • 2
    • 0031961764 scopus 로고    scopus 로고
    • Identification of amino acid residues of the NR2A subunit that control glutamate potency in recombinant NR1/NR2A NMDA receptors
    • Anson L.C., Chen P.E., Wyllie D.J., Colquhoun D., Schoepfer R. Identification of amino acid residues of the NR2A subunit that control glutamate potency in recombinant NR1/NR2A NMDA receptors. J. Neurosci. 1998, 18:581-589.
    • (1998) J. Neurosci. , vol.18 , pp. 581-589
    • Anson, L.C.1    Chen, P.E.2    Wyllie, D.J.3    Colquhoun, D.4    Schoepfer, R.5
  • 3
    • 10344263901 scopus 로고    scopus 로고
    • Conformations of variably linked chimeric proteins evaluated by synchrotron X-ray small-angle scattering
    • Arai R., Wriggers W., Nishikawa Y., Nagamune T., Fujisawa T. Conformations of variably linked chimeric proteins evaluated by synchrotron X-ray small-angle scattering. Proteins 2004, 57:829-838.
    • (2004) Proteins , vol.57 , pp. 829-838
    • Arai, R.1    Wriggers, W.2    Nishikawa, Y.3    Nagamune, T.4    Fujisawa, T.5
  • 4
    • 80755153558 scopus 로고    scopus 로고
    • Glutamate receptor dynamics and protein interaction: lessons from the NMDA receptor
    • Bard L., Groc L. Glutamate receptor dynamics and protein interaction: lessons from the NMDA receptor. Mol. Cell. Neurosci. 2011, 48:298-307.
    • (2011) Mol. Cell. Neurosci. , vol.48 , pp. 298-307
    • Bard, L.1    Groc, L.2
  • 5
    • 0025974234 scopus 로고
    • Kinetic analysis of antagonist action at N-methyl-D-aspartic acid receptors. Two binding sites each for glutamate and glycine
    • Benveniste M., Mayer M.L. Kinetic analysis of antagonist action at N-methyl-D-aspartic acid receptors. Two binding sites each for glutamate and glycine. Biophys. J. 1991, 59:560-573.
    • (1991) Biophys. J. , vol.59 , pp. 560-573
    • Benveniste, M.1    Mayer, M.L.2
  • 7
    • 3042546515 scopus 로고    scopus 로고
    • Molecular structure and physiological functions of GABA(B) receptors
    • Bettler B., Kaupmann K., Mosbacher J., Gassmann M. Molecular structure and physiological functions of GABA(B) receptors. Physiol. Rev. 2004, 84:835-867.
    • (2004) Physiol. Rev. , vol.84 , pp. 835-867
    • Bettler, B.1    Kaupmann, K.2    Mosbacher, J.3    Gassmann, M.4
  • 8
    • 84871569722 scopus 로고    scopus 로고
    • Effect of ifenprodil on GluN1/GluN2B N-methyl-D-aspartate receptor gating
    • Bhatt J.M., Prakash A., Suryavanshi P.S., Dravid S.M. Effect of ifenprodil on GluN1/GluN2B N-methyl-D-aspartate receptor gating. Mol. Pharmacol. 2013, 83:9-21.
    • (2013) Mol. Pharmacol. , vol.83 , pp. 9-21
    • Bhatt, J.M.1    Prakash, A.2    Suryavanshi, P.S.3    Dravid, S.M.4
  • 9
    • 0038790486 scopus 로고    scopus 로고
    • NR2B and NR2D subunits coassemble in cerebellar Golgi cells to form a distinct NMDA receptor subtype restricted to extrasynaptic sites
    • Brickley S.G., Misra C., Mok M.H., Mishina M., Cull-Candy S.G. NR2B and NR2D subunits coassemble in cerebellar Golgi cells to form a distinct NMDA receptor subtype restricted to extrasynaptic sites. J. Neurosci. 2003, 23:4958-4966.
    • (2003) J. Neurosci. , vol.23 , pp. 4958-4966
    • Brickley, S.G.1    Misra, C.2    Mok, M.H.3    Mishina, M.4    Cull-Candy, S.G.5
  • 10
    • 28644432057 scopus 로고    scopus 로고
    • Assembly-dependent surface targeting of the heterodimeric GABAB receptor is controlled by COPI but not 14-3-3
    • Brock C., Boudier L., Maurel D., Blahos J., Pin J.P. Assembly-dependent surface targeting of the heterodimeric GABAB receptor is controlled by COPI but not 14-3-3. Mol. Biol. Cell 2005, 16:5572-5578.
    • (2005) Mol. Biol. Cell , vol.16 , pp. 5572-5578
    • Brock, C.1    Boudier, L.2    Maurel, D.3    Blahos, J.4    Pin, J.P.5
  • 12
    • 0034663159 scopus 로고    scopus 로고
    • Developmental profile of the changing properties of NMDA receptors at cerebellar mossy fiber-granule cell synapses
    • Cathala L., Misra C., Cull-Candy S. Developmental profile of the changing properties of NMDA receptors at cerebellar mossy fiber-granule cell synapses. J. Neurosci. 2000, 20:5899-5905.
    • (2000) J. Neurosci. , vol.20 , pp. 5899-5905
    • Cathala, L.1    Misra, C.2    Cull-Candy, S.3
  • 13
    • 0030808687 scopus 로고    scopus 로고
    • Molecular dissection of native mammalian forebrain NMDA receptors containing the NR1 C2 exon: direct demonstration of NMDA receptors comprising NR1, NR2A, and NR2B subunits within the same complex
    • Chazot P.L., Stephenson F.A. Molecular dissection of native mammalian forebrain NMDA receptors containing the NR1 C2 exon: direct demonstration of NMDA receptors comprising NR1, NR2A, and NR2B subunits within the same complex. J. Neurochem. 1997, 69:2138-2144.
    • (1997) J. Neurochem. , vol.69 , pp. 2138-2144
    • Chazot, P.L.1    Stephenson, F.A.2
  • 14
    • 0027938709 scopus 로고
    • Molecular characterization of N-methyl-D-aspartate receptors expressed in mammalian cells yields evidence for the coexistence of three subunit types within a discrete receptor molecule
    • Chazot P.L., Coleman S.K., Cik M., Stephenson F.A. Molecular characterization of N-methyl-D-aspartate receptors expressed in mammalian cells yields evidence for the coexistence of three subunit types within a discrete receptor molecule. J. Biol. Chem. 1994, 269:24403-24409.
    • (1994) J. Biol. Chem. , vol.269 , pp. 24403-24409
    • Chazot, P.L.1    Coleman, S.K.2    Cik, M.3    Stephenson, F.A.4
  • 15
    • 0033136273 scopus 로고    scopus 로고
    • Identification and mechanism of action of two histidine residues underlying high-affinity Zn2+ inhibition of the NMDA receptor
    • Choi Y.B., Lipton S.A. Identification and mechanism of action of two histidine residues underlying high-affinity Zn2+ inhibition of the NMDA receptor. Neuron 1999, 23:171-180.
    • (1999) Neuron , vol.23 , pp. 171-180
    • Choi, Y.B.1    Lipton, S.A.2
  • 16
    • 0025944430 scopus 로고
    • Activation kinetics reveal the number of glutamate and glycine binding sites on the N-methyl-D-aspartate receptor
    • Clements J.D., Westbrook G.L. Activation kinetics reveal the number of glutamate and glycine binding sites on the N-methyl-D-aspartate receptor. Neuron 1991, 7:605-613.
    • (1991) Neuron , vol.7 , pp. 605-613
    • Clements, J.D.1    Westbrook, G.L.2
  • 17
    • 29244474382 scopus 로고    scopus 로고
    • Allosteric interaction between zinc and glutamate binding domains on NR2A causes desensitization of NMDA receptors
    • Erreger K., Traynelis S.F. Allosteric interaction between zinc and glutamate binding domains on NR2A causes desensitization of NMDA receptors. J. Physiol. 2005, 569:381-393.
    • (2005) J. Physiol. , vol.569 , pp. 381-393
    • Erreger, K.1    Traynelis, S.F.2
  • 18
    • 38849170353 scopus 로고    scopus 로고
    • Zinc inhibition of rat NR1/NR2A N-methyl-D-aspartate receptors
    • Erreger K., Traynelis S.F. Zinc inhibition of rat NR1/NR2A N-methyl-D-aspartate receptors. J. Physiol. 2008, 586:763-778.
    • (2008) J. Physiol. , vol.586 , pp. 763-778
    • Erreger, K.1    Traynelis, S.F.2
  • 20
    • 0030909728 scopus 로고    scopus 로고
    • NR2A subunit expression shortens NMDA receptor synaptic currents in developing neocortex
    • Flint A.C., Maisch U.S., Weishaupt J.H., Kriegstein A.R., Monyer H. NR2A subunit expression shortens NMDA receptor synaptic currents in developing neocortex. J. Neurosci. 1997, 17:2469-2476.
    • (1997) J. Neurosci. , vol.17 , pp. 2469-2476
    • Flint, A.C.1    Maisch, U.S.2    Weishaupt, J.H.3    Kriegstein, A.R.4    Monyer, H.5
  • 21
    • 80052188595 scopus 로고    scopus 로고
    • Distinct modes of AMPA receptor suppression at developing synapses by GluN2A and GluN2B: single-cell NMDA receptor subunit deletion in vivo
    • Gray J.A., Shi Y., Usui H., During M.J., Sakimura K., Nicoll R.A. Distinct modes of AMPA receptor suppression at developing synapses by GluN2A and GluN2B: single-cell NMDA receptor subunit deletion in vivo. Neuron 2011, 71:1085-1101.
    • (2011) Neuron , vol.71 , pp. 1085-1101
    • Gray, J.A.1    Shi, Y.2    Usui, H.3    During, M.J.4    Sakimura, K.5    Nicoll, R.A.6
  • 23
    • 84860321928 scopus 로고    scopus 로고
    • Subunit-selective allosteric inhibition of glycine binding to NMDA receptors
    • Hansen K.B., Ogden K.K., Traynelis S.F. Subunit-selective allosteric inhibition of glycine binding to NMDA receptors. J. Neurosci. 2012, 32:6197-6208.
    • (2012) J. Neurosci. , vol.32 , pp. 6197-6208
    • Hansen, K.B.1    Ogden, K.K.2    Traynelis, S.F.3
  • 25
    • 17444426068 scopus 로고    scopus 로고
    • Modulation of triheteromeric NMDA receptors by N-terminal domain ligands
    • Hatton C.J., Paoletti P. Modulation of triheteromeric NMDA receptors by N-terminal domain ligands. Neuron 2005, 46:261-274.
    • (2005) Neuron , vol.46 , pp. 261-274
    • Hatton, C.J.1    Paoletti, P.2
  • 26
    • 28244493418 scopus 로고    scopus 로고
    • Functional NR2B- and NR2D-containing NMDA receptor channels in rat substantia nigra dopaminergic neurones
    • Jones S., Gibb A.J. Functional NR2B- and NR2D-containing NMDA receptor channels in rat substantia nigra dopaminergic neurones. J. Physiol. 2005, 569:209-221.
    • (2005) J. Physiol. , vol.569 , pp. 209-221
    • Jones, S.1    Gibb, A.J.2
  • 27
    • 0032589511 scopus 로고    scopus 로고
    • Heterodimerization of a functional GABAB receptor is mediated by parallel coiled-coil alpha-helices
    • Kammerer R.A., Frank S., Schulthess T., Landwehr R., Lustig A., Engel J. Heterodimerization of a functional GABAB receptor is mediated by parallel coiled-coil alpha-helices. Biochemistry 1999, 38:13263-13269.
    • (1999) Biochemistry , vol.38 , pp. 13263-13269
    • Kammerer, R.A.1    Frank, S.2    Schulthess, T.3    Landwehr, R.4    Lustig, A.5    Engel, J.6
  • 28
    • 72449151659 scopus 로고    scopus 로고
    • Structure of the zinc-bound amino-terminal domain of the NMDA receptor NR2B subunit
    • Karakas E., Simorowski N., Furukawa H. Structure of the zinc-bound amino-terminal domain of the NMDA receptor NR2B subunit. EMBO J. 2009, 28:3910-3920.
    • (2009) EMBO J. , vol.28 , pp. 3910-3920
    • Karakas, E.1    Simorowski, N.2    Furukawa, H.3
  • 29
    • 79960417429 scopus 로고    scopus 로고
    • Subunit arrangement and phenylethanolamine binding in GluN1/GluN2B NMDA receptors
    • Karakas E., Simorowski N., Furukawa H. Subunit arrangement and phenylethanolamine binding in GluN1/GluN2B NMDA receptors. Nature 2011, 475:249-253.
    • (2011) Nature , vol.475 , pp. 249-253
    • Karakas, E.1    Simorowski, N.2    Furukawa, H.3
  • 30
    • 0030450983 scopus 로고    scopus 로고
    • A novel mechanism of activity-dependent NMDA receptor antagonism describes the effect of ifenprodil in rat cultured cortical neurones
    • Kew J.N., Trube G., Kemp J.A. A novel mechanism of activity-dependent NMDA receptor antagonism describes the effect of ifenprodil in rat cultured cortical neurones. J. Physiol. 1996, 497:761-772.
    • (1996) J. Physiol. , vol.497 , pp. 761-772
    • Kew, J.N.1    Trube, G.2    Kemp, J.A.3
  • 31
    • 0032521090 scopus 로고    scopus 로고
    • Developmental changes in NMDA receptor glycine affinity and ifenprodil sensitivity reveal three distinct populations of NMDA receptors in individual rat cortical neurons
    • Kew J.N., Richards J.G., Mutel V., Kemp J.A. Developmental changes in NMDA receptor glycine affinity and ifenprodil sensitivity reveal three distinct populations of NMDA receptors in individual rat cortical neurons. J. Neurosci. 1998, 18:1935-1943.
    • (1998) J. Neurosci. , vol.18 , pp. 1935-1943
    • Kew, J.N.1    Richards, J.G.2    Mutel, V.3    Kemp, J.A.4
  • 32
    • 0029950357 scopus 로고    scopus 로고
    • Synaptic NMDA receptors in developing mouse hippocampal neurones: functional properties and sensitivity to ifenprodil
    • Kirson E.D., Yaari Y. Synaptic NMDA receptors in developing mouse hippocampal neurones: functional properties and sensitivity to ifenprodil. J. Physiol. 1996, 497:437-455.
    • (1996) J. Physiol. , vol.497 , pp. 437-455
    • Kirson, E.D.1    Yaari, Y.2
  • 33
  • 34
    • 0030991790 scopus 로고    scopus 로고
    • Molecular determinants of agonist discrimination by NMDA receptor subunits: analysis of the glutamate binding site on the NR2B subunit
    • Laube B., Hirai H., Sturgess M., Betz H., Kuhse J. Molecular determinants of agonist discrimination by NMDA receptor subunits: analysis of the glutamate binding site on the NR2B subunit. Neuron 1997, 18:493-503.
    • (1997) Neuron , vol.18 , pp. 493-503
    • Laube, B.1    Hirai, H.2    Sturgess, M.3    Betz, H.4    Kuhse, J.5
  • 35
    • 0025368726 scopus 로고
    • Channel kinetics determine the time course of NMDA receptor-mediated synaptic currents
    • Lester R.A., Clements J.D., Westbrook G.L., Jahr C.E. Channel kinetics determine the time course of NMDA receptor-mediated synaptic currents. Nature 1990, 346:565-567.
    • (1990) Nature , vol.346 , pp. 565-567
    • Lester, R.A.1    Clements, J.D.2    Westbrook, G.L.3    Jahr, C.E.4
  • 36
    • 0034718494 scopus 로고    scopus 로고
    • Molecular determinants of coordinated proton and zinc inhibition of N-methyl-D-aspartate NR1/NR2A receptors
    • Low C.M., Zheng F., Lyuboslavsky P., Traynelis S.F. Molecular determinants of coordinated proton and zinc inhibition of N-methyl-D-aspartate NR1/NR2A receptors. Proc. Natl. Acad. Sci. USA 2000, 97:11062-11067.
    • (2000) Proc. Natl. Acad. Sci. USA , vol.97 , pp. 11062-11067
    • Low, C.M.1    Zheng, F.2    Lyuboslavsky, P.3    Traynelis, S.F.4
  • 37
    • 0031032658 scopus 로고    scopus 로고
    • The majority of N-methyl-D-aspartate receptor complexes in adult rat cerebral cortex contain at least three different subunits (NR1/NR2A/NR2B)
    • Luo J., Wang Y., Yasuda R.P., Dunah A.W., Wolfe B.B. The majority of N-methyl-D-aspartate receptor complexes in adult rat cerebral cortex contain at least three different subunits (NR1/NR2A/NR2B). Mol. Pharmacol. 1997, 51:79-86.
    • (1997) Mol. Pharmacol. , vol.51 , pp. 79-86
    • Luo, J.1    Wang, Y.2    Yasuda, R.P.3    Dunah, A.W.4    Wolfe, B.B.5
  • 38
    • 84867815125 scopus 로고    scopus 로고
    • C-terminal domains of N-methyl-D-aspartic acid receptor modulate unitary channel conductance and gating
    • Maki B.A., Aman T.K., Amico-Ruvio S.A., Kussius C.L., Popescu G.K. C-terminal domains of N-methyl-D-aspartic acid receptor modulate unitary channel conductance and gating. J. Biol. Chem. 2012, 287:36071-36080.
    • (2012) J. Biol. Chem. , vol.287 , pp. 36071-36080
    • Maki, B.A.1    Aman, T.K.2    Amico-Ruvio, S.A.3    Kussius, C.L.4    Popescu, G.K.5
  • 39
    • 0033667466 scopus 로고    scopus 로고
    • A trafficking checkpoint controls GABA(B) receptor heterodimerization
    • Margeta-Mitrovic M., Jan Y.N., Jan L.Y. A trafficking checkpoint controls GABA(B) receptor heterodimerization. Neuron 2000, 27:97-106.
    • (2000) Neuron , vol.27 , pp. 97-106
    • Margeta-Mitrovic, M.1    Jan, Y.N.2    Jan, L.Y.3
  • 41
    • 0030746608 scopus 로고    scopus 로고
    • High-affinity zinc inhibition of NMDA NR1-NR2A receptors
    • Paoletti P., Ascher P., Neyton J. High-affinity zinc inhibition of NMDA NR1-NR2A receptors. J. Neurosci. 1997, 17:5711-5725.
    • (1997) J. Neurosci. , vol.17 , pp. 5711-5725
    • Paoletti, P.1    Ascher, P.2    Neyton, J.3
  • 42
    • 0034517709 scopus 로고    scopus 로고
    • Molecular organization of a zinc binding n-terminal modulatory domain in a NMDA receptor subunit
    • Paoletti P., Perin-Dureau F., Fayyazuddin A., Le Goff A., Callebaut I., Neyton J. Molecular organization of a zinc binding n-terminal modulatory domain in a NMDA receptor subunit. Neuron 2000, 28:911-925.
    • (2000) Neuron , vol.28 , pp. 911-925
    • Paoletti, P.1    Perin-Dureau, F.2    Fayyazuddin, A.3    Le Goff, A.4    Callebaut, I.5    Neyton, J.6
  • 43
    • 84878254691 scopus 로고    scopus 로고
    • NMDA receptor subunit diversity: impact on receptor properties, synaptic plasticity and disease
    • Paoletti P., Bellone C., Zhou Q. NMDA receptor subunit diversity: impact on receptor properties, synaptic plasticity and disease. Nat. Rev. Neurosci. 2013, 14:383-400.
    • (2013) Nat. Rev. Neurosci. , vol.14 , pp. 383-400
    • Paoletti, P.1    Bellone, C.2    Zhou, Q.3
  • 44
    • 0037095835 scopus 로고    scopus 로고
    • Subtypes of NMDA receptors in new-born rat hippocampal granule cells
    • Piña-Crespo J.C., Gibb A.J. Subtypes of NMDA receptors in new-born rat hippocampal granule cells. J. Physiol. 2002, 541:41-64.
    • (2002) J. Physiol. , vol.541 , pp. 41-64
    • Piña-Crespo, J.C.1    Gibb, A.J.2
  • 45
    • 59049098262 scopus 로고    scopus 로고
    • An innovative design to establish proof of concept of the antidepressant effects of the NR2B subunit selective N-methyl-D-aspartate antagonist, CP-101,606, in patients with treatment-refractory major depressive disorder
    • Preskorn S.H., Baker B., Kolluri S., Menniti F.S., Krams M., Landen J.W. An innovative design to establish proof of concept of the antidepressant effects of the NR2B subunit selective N-methyl-D-aspartate antagonist, CP-101,606, in patients with treatment-refractory major depressive disorder. J. Clin. Psychopharmacol. 2008, 28:631-637.
    • (2008) J. Clin. Psychopharmacol. , vol.28 , pp. 631-637
    • Preskorn, S.H.1    Baker, B.2    Kolluri, S.3    Menniti, F.S.4    Krams, M.5    Landen, J.W.6
  • 46
    • 84857064886 scopus 로고    scopus 로고
    • Influence of the intracellular GluN2 C-terminal domain on NMDA receptor function
    • Punnakkal P., Jendritza P., Köhr G. Influence of the intracellular GluN2 C-terminal domain on NMDA receptor function. Neuropharmacology 2012, 62:1985-1992.
    • (2012) Neuropharmacology , vol.62 , pp. 1985-1992
    • Punnakkal, P.1    Jendritza, P.2    Köhr, G.3
  • 48
    • 79953199424 scopus 로고    scopus 로고
    • Triheteromeric NR1/NR2A/NR2B receptors constitute the major N-methyl-D-aspartate receptor population in adult hippocampal synapses
    • Rauner C., Köhr G. Triheteromeric NR1/NR2A/NR2B receptors constitute the major N-methyl-D-aspartate receptor population in adult hippocampal synapses. J. Biol. Chem. 2011, 286:7558-7566.
    • (2011) J. Biol. Chem. , vol.286 , pp. 7558-7566
    • Rauner, C.1    Köhr, G.2
  • 49
    • 84871558287 scopus 로고    scopus 로고
    • Diversity in NMDA receptor composition: many regulators, many consequences
    • Sanz-Clemente A., Nicoll R.A., Roche K.W. Diversity in NMDA receptor composition: many regulators, many consequences. Neuroscientist 2013, 19:62-75.
    • (2013) Neuroscientist , vol.19 , pp. 62-75
    • Sanz-Clemente, A.1    Nicoll, R.A.2    Roche, K.W.3
  • 51
    • 0028219211 scopus 로고
    • Changing subunit composition of heteromeric NMDA receptors during development of rat cortex
    • Sheng M., Cummings J., Roldan L.A., Jan Y.N., Jan L.Y. Changing subunit composition of heteromeric NMDA receptors during development of rat cortex. Nature 1994, 368:144-147.
    • (1994) Nature , vol.368 , pp. 144-147
    • Sheng, M.1    Cummings, J.2    Roldan, L.A.3    Jan, Y.N.4    Jan, L.Y.5
  • 52
    • 0032520117 scopus 로고    scopus 로고
    • Increased contribution of NR2A subunit to synaptic NMDA receptors in developing rat cortical neurons
    • Stocca G., Vicini S. Increased contribution of NR2A subunit to synaptic NMDA receptors in developing rat cortical neurons. J. Physiol. 1998, 507:13-24.
    • (1998) J. Physiol. , vol.507 , pp. 13-24
    • Stocca, G.1    Vicini, S.2
  • 53
    • 77954229017 scopus 로고    scopus 로고
    • Novel approach to probe subunit-specific contributions to N-methyl-D-aspartate (NMDA) receptor trafficking reveals a dominant role for NR2B in receptor recycling
    • Tang T.T., Badger J.D., Roche P.A., Roche K.W. Novel approach to probe subunit-specific contributions to N-methyl-D-aspartate (NMDA) receptor trafficking reveals a dominant role for NR2B in receptor recycling. J. Biol. Chem. 2010, 285:20975-20981.
    • (2010) J. Biol. Chem. , vol.285 , pp. 20975-20981
    • Tang, T.T.1    Badger, J.D.2    Roche, P.A.3    Roche, K.W.4
  • 54
    • 0033562610 scopus 로고    scopus 로고
    • The incorporation of NMDA receptors with a distinct subunit composition at nascent hippocampal synapses in vitro
    • Tovar K.R., Westbrook G.L. The incorporation of NMDA receptors with a distinct subunit composition at nascent hippocampal synapses in vitro. J. Neurosci. 1999, 19:4180-4188.
    • (1999) J. Neurosci. , vol.19 , pp. 4180-4188
    • Tovar, K.R.1    Westbrook, G.L.2
  • 55
    • 84861914679 scopus 로고    scopus 로고
    • Amino-terminal ligands prolong NMDA Receptor-mediated EPSCs
    • Tovar K.R., Westbrook G.L. Amino-terminal ligands prolong NMDA Receptor-mediated EPSCs. J. Neurosci. 2012, 32:8065-8073.
    • (2012) J. Neurosci. , vol.32 , pp. 8065-8073
    • Tovar, K.R.1    Westbrook, G.L.2
  • 56
    • 84877931450 scopus 로고    scopus 로고
    • Triheteromeric NMDA receptors at hippocampal synapses
    • Tovar K.R., McGinley M.J., Westbrook G.L. Triheteromeric NMDA receptors at hippocampal synapses. J. Neurosci. 2013, 33:9150-9160.
    • (2013) J. Neurosci. , vol.33 , pp. 9150-9160
    • Tovar, K.R.1    McGinley, M.J.2    Westbrook, G.L.3
  • 57
    • 0032529588 scopus 로고    scopus 로고
    • Control of voltage-independent zinc inhibition of NMDA receptors by the NR1 subunit
    • Traynelis S.F., Burgess M.F., Zheng F., Lyuboslavsky P., Powers J.L. Control of voltage-independent zinc inhibition of NMDA receptors by the NR1 subunit. J. Neurosci. 1998, 18:6163-6175.
    • (1998) J. Neurosci. , vol.18 , pp. 6163-6175
    • Traynelis, S.F.1    Burgess, M.F.2    Zheng, F.3    Lyuboslavsky, P.4    Powers, J.L.5
  • 60
    • 0030606839 scopus 로고    scopus 로고
    • Separating dual effects of zinc at recombinant N-methyl-D-aspartate receptors
    • Williams K. Separating dual effects of zinc at recombinant N-methyl-D-aspartate receptors. Neurosci. Lett. 1996, 215:9-12.
    • (1996) Neurosci. Lett. , vol.215 , pp. 9-12
    • Williams, K.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.