Structural determinants of agonist efficacy at the glutamate binding site of n-methyl-d-Aspartate receptorss

Molecular Pharmacology

Volumn 84, Issue 1, 2013, Pages 114-127

  Hansen, Kasper B ^a   Tajima, Nami ^b   Risgaard, Rune ^c   Perszyk, Riley E ^a   Jorgensen, Lars ^c   Vance, Katie M ^a   Ogden, Kevin K ^a   Clausen, Rasmus P ^c   Furukawa, Hiro ^b   Traynelis, Stephen F ^a  

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b Howard Hughes Medical Institute Cold Spring Harbor Laboratory Cold Spring Harbor   (United States)

^c UNIVERSITY OF COPENHAGEN   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

GLUTAMIC ACID; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; PARTIAL AGONIST;

AMINO TERMINAL SEQUENCE; ARTICLE; CRYSTAL STRUCTURE; DRUG BINDING SITE; DRUG EFFICACY; DRUG STRUCTURE; ELECTROPHYSIOLOGY; HUMAN; NUCLEOTIDE SEQUENCE; PARTIAL AGONISM; PATCH CLAMP; PRIORITY JOURNAL; VOLTAGE CLAMP;

ALPHA-AMINO-3-HYDROXY-5-METHYL-4-ISOXAZOLEPROPIONIC ACID; ANIMALS; BINDING SITES; CELLS, CULTURED; EXCITATORY AMINO ACID AGONISTS; FEMALE; GLUTAMIC ACID; GLYCINE; HEK293 CELLS; HUMANS; PROTEIN STRUCTURE, TERTIARY; PROTEIN SUBUNITS; RECEPTORS, KAINIC ACID; RECEPTORS, N-METHYL-D-ASPARTATE; XENOPUS LAEVIS;

EID: 84879087027     PISSN: 0026895X     EISSN: 15210111     Source Type: Journal    
DOI: 10.1124/mol.113.085803     Document Type: Article

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