Pre-B Cell Receptor Signaling Induces Immunoglobulin κ Locus Accessibility by Functional Redistribution of Enhancer-Mediated Chromatin Interactions

PLoS Biology

Volumn 12, Issue 2, 2014, Pages

  Stadhouders, Ralph ^a   de Bruijn, Marjolein J W ^a   Rother, Magdalena B ^a   Yuvaraj, Saravanan ^a   de Almeida, Claudia Ribeiro ^a,c   Kolovos, Petros ^a   Van Zelm, Menno C ^a   van Ijcken, Wilfred ^a   Grosveld, Frank ^a   Soler, Eric ^a,b   Hendriks, Rudi W ^a  

^a ERASMUS MEDICAL CENTER   (Netherlands)

^b INSTITUT DE RADIOPROTECTION ET DE SÛRETÉ NUCLÉAIRE   (France)

^c UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BRUTON TYROSINE KINASE; IMMUNOGLOBULIN KAPPA CHAIN; PRE B CELL RECEPTOR; PROTEIN SH2; RECOMBINASE; TRANSCRIPTION FACTOR E2A;

ANIMAL CELL; ARTICLE; CELLULAR DISTRIBUTION; CHROMATIN; CONTROLLED STUDY; DNA FLANKING REGION; ENHANCER REGION; GENE CONTROL; GENE IDENTIFICATION; GENE LOCUS; GENE REARRANGEMENT; IGK GENE; IMMUNOGLOBULIN GENE; INTRACELLULAR SIGNALING; INTRON; MOLECULAR INTERACTION; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE;

ANIMALS; CELLS, CULTURED; CHROMATIN; CHROMATIN ASSEMBLY AND DISASSEMBLY; ENHANCER ELEMENTS, GENETIC; EPISTASIS, GENETIC; HISTONES; IMMUNOGLOBULIN KAPPA-CHAINS; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; PRECURSOR CELLS, B-LYMPHOID; PROTEIN PROCESSING, POST-TRANSLATIONAL; RECEPTORS, ANTIGEN, B-CELL; SIGNAL TRANSDUCTION; TRANSCRIPTOME; V(D)J RECOMBINATION;

EID: 84895469203     PISSN: 15449173     EISSN: 15457885     Source Type: Journal    
DOI: 10.1371/journal.pbio.1001791     Document Type: Article

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