-
1
-
-
43549111150
-
IAPs: More than just inhibitors of apoptosis proteins
-
Dubrez-Daloz, L.; Dupoux, A.; Cartier, J. IAPs: More than just inhibitors of apoptosis proteins. Cell. Cycle 2008, 7, 1036-1046.
-
(2008)
Cell. Cycle
, vol.7
, pp. 1036-1046
-
-
Dubrez-Daloz, L.1
Dupoux, A.2
Cartier, J.3
-
2
-
-
77954930632
-
IAPs: From caspase inhibitors to modulators of NF-kappaB, inflammation and cancer
-
Gyrd-Hansen, M.; Meier, P. IAPs: From caspase inhibitors to modulators of NF-kappaB, inflammation and cancer. Nat. Rev. Cancer 2010, 10, 561-574.
-
(2010)
Nat. Rev. Cancer
, vol.10
, pp. 561-574
-
-
Gyrd-Hansen, M.1
Meier, P.2
-
4
-
-
2342430610
-
Translational induction of the inhibitor of apoptosis protein HIAP2 during endoplasmic reticulum stress attenuates cell death and is mediated via an inducible internal ribosome entry site element
-
Warnakulasuriyarachchi, D.; Cerquozzi, S.; Cheung, H.H.; Holcik, M. Translational induction of the inhibitor of apoptosis protein HIAP2 during endoplasmic reticulum stress attenuates cell death and is mediated via an inducible internal ribosome entry site element. J. Biol. Chem. 2004, 279, 17148-17157.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 17148-17157
-
-
Warnakulasuriyarachchi, D.1
Cerquozzi, S.2
Cheung, H.H.3
Holcik, M.4
-
5
-
-
1242273881
-
Translation of cellular inhibitor of apoptosis protein 1 (c-IAP1) mRNA is IRES mediated and regulated during cell stress
-
Van Eden, M.E.; Byrd, M.P.; Sherrill, K.W.; Lloyd, R.E. Translation of cellular inhibitor of apoptosis protein 1 (c-IAP1) mRNA is IRES mediated and regulated during cell stress. RNA 2004, 10, 469-481.
-
(2004)
RNA
, vol.10
, pp. 469-481
-
-
van Eden, M.E.1
Byrd, M.P.2
Sherrill, K.W.3
Lloyd, R.E.4
-
6
-
-
0033160190
-
A new internal-ribosome-entry-site motif potentiates XIAP-mediated cytoprotection
-
Holcik, M.; Lefebvre, C.; Yeh, C.; Chow, T.; Korneluk, R.G. A new internal-ribosome-entry-site motif potentiates XIAP-mediated cytoprotection. Nat. Cell. Biol. 1999, 1, 190-192.
-
(1999)
Nat. Cell. Biol.
, vol.1
, pp. 190-192
-
-
Holcik, M.1
Lefebvre, C.2
Yeh, C.3
Chow, T.4
Korneluk, R.G.5
-
7
-
-
42149087042
-
The mechanism of peptide-binding specificity of IAP BIR domains
-
Eckelman, B.P.; Drag, M.; Snipas, S.J.; Salvesen, G.S. The mechanism of peptide-binding specificity of IAP BIR domains. Cell. Death Differ. 2008, 15, 920-928.
-
(2008)
Cell. Death Differ.
, vol.15
, pp. 920-928
-
-
Eckelman, B.P.1
Drag, M.2
Snipas, S.J.3
Salvesen, G.S.4
-
8
-
-
79959539790
-
Ubiquitylation in apoptosis: A post-translational modification at the edge of life and death
-
Vucic, D.; Dixit, V.M.; Wertz, I.E., Ubiquitylation in apoptosis: a post-translational modification at the edge of life and death. Nat. Rev. Mol. Cell. Biol. 2011, 12, 439-452.
-
(2011)
Nat. Rev. Mol. Cell. Biol.
, vol.12
, pp. 439-452
-
-
Vucic, D.1
Dixit, V.M.2
Wertz, I.E.3
-
9
-
-
28044469866
-
Determination of cell survival by RING-mediated regulation of inhibitor of apoptosis (IAP) protein abundance
-
Silke, J.; Kratina, T.; Chu, D.; Ekert, P.G.; Day, C.L.; Pakusch, M.; Huang, D.C.; Vaux, D.L. Determination of cell survival by RING-mediated regulation of inhibitor of apoptosis (IAP) protein abundance. Proc. Natl. Acad. Sci. USA 2005, 102, 16182-16187.
-
(2005)
Proc. Natl. Acad. Sci.
, vol.102
, pp. 16182-16187
-
-
Silke, J.1
Kratina, T.2
Chu, D.3
Ekert, P.G.4
Day, C.L.5
Pakusch, M.6
Huang, D.C.7
Vaux, D.L.8
-
10
-
-
57649120782
-
Structures of the cIAP2 RING domain reveal conformational changes associated with ubiquitin-conjugating enzyme (E2) recruitment
-
Mace, P.D.; Linke, K.; Feltham, R.; Schumacher, F.R.; Smith, C.A.; Vaux, D.L.; Silke, J.; Day, C.L. Structures of the cIAP2 RING domain reveal conformational changes associated with ubiquitin-conjugating enzyme (E2) recruitment. J. Biol. Chem. 2008, 283, 31633-31640.
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 31633-31640
-
-
Mace, P.D.1
Linke, K.2
Feltham, R.3
Schumacher, F.R.4
Smith, C.A.5
Vaux, D.L.6
Silke, J.7
Day, C.L.8
-
11
-
-
51349130944
-
The RING domain of cIAP1 mediates the degradation of RING-bearing inhibitor of apoptosis proteins by distinct pathways
-
Cheung, H.H.; Plenchette, S.; Kern, C.J.; Mahoney, D.J.; Korneluk, R.G. The RING domain of cIAP1 mediates the degradation of RING-bearing inhibitor of apoptosis proteins by distinct pathways. Mol. Biol. Cell. 2008, 19, 2729-2740.
-
(2008)
Mol. Biol. Cell.
, vol.19
, pp. 2729-2740
-
-
Cheung, H.H.1
Plenchette, S.2
Kern, C.J.3
Mahoney, D.J.4
Korneluk, R.G.5
-
12
-
-
33750485792
-
IAP-IAP complexes required for apoptosis resistance of C. trachomatis-infected cells
-
Rajalingam, K.; Sharma, M.; Paland, N.; Hurwitz, R.; Thieck, O.; Oswald, M.; Machuy, N.; Rudel, T. IAP-IAP complexes required for apoptosis resistance of C. trachomatis-infected cells. PLoS Pathog. 2006, 2, e114.
-
(2006)
PLoS Pathog.
, vol.2
-
-
Rajalingam, K.1
Sharma, M.2
Paland, N.3
Hurwitz, R.4
Thieck, O.5
Oswald, M.6
Machuy, N.7
Rudel, T.8
-
13
-
-
4544261227
-
An IAP-IAP complex inhibits apoptosis
-
Dohi, T.; Okada, K.; Xia, F.; Wilford, C.E.; Samuel, T.; Welsh, K.; Marusawa, H.; Zou, H.; Armstrong, R.; Matsuzawa, S.; et al. An IAP-IAP complex inhibits apoptosis. J. Biol. Chem. 2004, 279, 34087-34090.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 34087-34090
-
-
Dohi, T.1
Okada, K.2
Xia, F.3
Wilford, C.E.4
Samuel, T.5
Welsh, K.6
Marusawa, H.7
Zou, H.8
Armstrong, R.9
Matsuzawa, S.10
-
14
-
-
0034607655
-
Ubiquitin protein ligase activity of IAPs and their degradation in proteasomes in response to apoptotic stimuli
-
Yang, Y.; Fang, S.; Jensen, J.P.; Weissman, A.M.; Ashwell, J.D. Ubiquitin protein ligase activity of IAPs and their degradation in proteasomes in response to apoptotic stimuli. Science 2000, 288, 874-877.
-
(2000)
Science
, vol.288
, pp. 874-877
-
-
Yang, Y.1
Fang, S.2
Jensen, J.P.3
Weissman, A.M.4
Ashwell, J.D.5
-
15
-
-
4444329609
-
Apollon ubiquitinates SMAC and caspase-9, and has an essential cytoprotection function
-
Hao, Y.; Sekine, K.; Kawabata, A.; Nakamura, H.; Ishioka, T.; Ohata, H.; Katayama, R.; Hashimoto, C.; Zhang, X.; Noda, T.; et al. Apollon ubiquitinates SMAC and caspase-9, and has an essential cytoprotection function. Nat. Cell. Biol. 2004, 6, 849-860.
-
(2004)
Nat. Cell. Biol.
, vol.6
, pp. 849-860
-
-
Hao, Y.1
Sekine, K.2
Kawabata, A.3
Nakamura, H.4
Ishioka, T.5
Ohata, H.6
Katayama, R.7
Hashimoto, C.8
Zhang, X.9
Noda, T.10
-
16
-
-
58249086500
-
Ubiquitin binding modulates IAP antagonist-stimulated proteasomal degradation of c-IAP1 and c-IAP2(1)
-
Blankenship, J.W.; Varfolomeev, E.; Goncharov, T.; Fedorova, A.V.; Kirkpatrick, D.S.; Izrael-Tomasevic, A.; Phu, L.; Arnott, D.; Aghajan, M.; Zobel, K.; et al. Ubiquitin binding modulates IAP antagonist-stimulated proteasomal degradation of c-IAP1 and c-IAP2(1). Biochem. J. 2009, 417, 149-160.
-
(2009)
Biochem. J.
, vol.417
, pp. 149-160
-
-
Blankenship, J.W.1
Varfolomeev, E.2
Goncharov, T.3
Fedorova, A.V.4
Kirkpatrick, D.S.5
Izrael-Tomasevic, A.6
Phu, L.7
Arnott, D.8
Aghajan, M.9
Zobel, K.10
-
17
-
-
55549140475
-
IAPs contain an evolutionarily conserved ubiquitin-binding domain that regulates NF-kappaB as well as cell survival and oncogenesis
-
Gyrd-Hansen, M.; Darding, M.; Miasari, M.; Santoro, M.M.; Zender, L.; Xue, W.; Tenev, T.; da Fonseca, P.C.; Zvelebil, M.; Bujnicki, J.M.; et al. IAPs contain an evolutionarily conserved ubiquitin-binding domain that regulates NF-kappaB as well as cell survival and oncogenesis. Nat. Cell. Biol. 2008, 10, 1309-1317.
-
(2008)
Nat. Cell. Biol.
, vol.10
, pp. 1309-1317
-
-
Gyrd-Hansen, M.1
Darding, M.2
Miasari, M.3
Santoro, M.M.4
Zender, L.5
Xue, W.6
Tenev, T.7
da Fonseca, P.C.8
Zvelebil, M.9
Bujnicki, J.M.10
-
18
-
-
79958051518
-
CARD-mediated autoinhibition of cIAP1's E3 ligase activity suppresses cell proliferation and migration
-
Lopez, J.; John, S.W.; Tenev, T.; Rautureau, G.J.; Hinds, M.G.; Francalanci, F.; Wilson, R.; Broemer, M.; Santoro, M.M.; Day, C.L.; et al. CARD-mediated autoinhibition of cIAP1's E3 ligase activity suppresses cell proliferation and migration. Mol. Cell. 2011, 42, 569-583.
-
(2011)
Mol. Cell.
, vol.42
, pp. 569-583
-
-
Lopez, J.1
John, S.W.2
Tenev, T.3
Rautureau, G.J.4
Hinds, M.G.5
Francalanci, F.6
Wilson, R.7
Broemer, M.8
Santoro, M.M.9
Day, C.L.10
-
19
-
-
0028896092
-
The gene for neuronal apoptosis inhibitory protein is partially deleted in individuals with spinal muscular atrophy
-
Roy, N.; Mahadevan, M.S.; McLean, M.; Shutler, G.; Yaraghi, Z.; Farahani, R.; Baird, S.; Besner-Johnston, A.; Lefebvre, C.; Kang, X.; et al. The gene for neuronal apoptosis inhibitory protein is partially deleted in individuals with spinal muscular atrophy. Cell 1995, 80, 167-178.
-
(1995)
Cell
, vol.80
, pp. 167-178
-
-
Roy, N.1
Mahadevan, M.S.2
McLean, M.3
Shutler, G.4
Yaraghi, Z.5
Farahani, R.6
Baird, S.7
Besner-Johnston, A.8
Lefebvre, C.9
Kang, X.10
-
20
-
-
84856495152
-
Targeting IAP proteins for therapeutic intervention in cancer
-
Fulda, S.; Vucic, D. Targeting IAP proteins for therapeutic intervention in cancer. Nat. Rev. Drug Discov. 2012, 11, 109-124.
-
(2012)
Nat. Rev. Drug Discov.
, vol.11
, pp. 109-124
-
-
Fulda, S.1
Vucic, D.2
-
21
-
-
69249100500
-
Human caspases: Activation, specificity, and regulation
-
Pop, C.; Salvesen, G.S. Human caspases: Activation, specificity, and regulation. J. Biol. Chem. 2009, 284, 21777-21781.
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 21777-21781
-
-
Pop, C.1
Salvesen, G.S.2
-
22
-
-
78649635776
-
Molecular cell death platforms and assemblies
-
Mace, P.D.; Riedl, S.J. Molecular cell death platforms and assemblies. Curr. Opin. Cell. Biol. 2010, 22, 828-836.
-
(2010)
Curr. Opin. Cell. Biol.
, vol.22
, pp. 828-836
-
-
Mace, P.D.1
Riedl, S.J.2
-
23
-
-
84861652703
-
The central role of initiator caspase-9 in apoptosis signal transduction and the regulation of its activation and activity on the apoptosome
-
Wurstle, M.L.; Laussmann, M.A.; Rehm, M. The central role of initiator caspase-9 in apoptosis signal transduction and the regulation of its activation and activity on the apoptosome. Exp. Cell. Res. 2012, 318, 121-320.
-
(2012)
Exp. Cell. Res.
, vol.318
, pp. 121-320
-
-
Wurstle, M.L.1
Laussmann, M.A.2
Rehm, M.3
-
24
-
-
79960922705
-
cIAPs block Ripoptosome formation, a RIP1/caspase-8 containing intracellular cell death complex differentially regulated by cFLIP isoforms
-
Feoktistova, M.; Geserick, P.; Kellert, B.; Dimitrova, D.P.; Langlais, C.; Hupe, M.; Cain, K.; MacFarlane, M.; Hacker, G.; Leverkus, M. cIAPs block Ripoptosome formation, a RIP1/caspase-8 containing intracellular cell death complex differentially regulated by cFLIP isoforms. Mol. Cell. 2011, 43, 449-463.
-
(2011)
Mol. Cell.
, vol.43
, pp. 449-463
-
-
Feoktistova, M.1
Geserick, P.2
Kellert, B.3
Dimitrova, D.P.4
Langlais, C.5
Hupe, M.6
Cain, K.7
MacFarlane, M.8
Hacker, G.9
Leverkus, M.10
-
25
-
-
79960921946
-
The Ripoptosome, a signaling platform that assembles in response to genotoxic stress and loss of IAPs
-
Tenev, T.; Bianchi, K.; Darding, M.; Broemer, M.; Langlais, C.; Wallberg, F.; Zachariou, A.; Lopez, J.; MacFarlane, M.; Cain, K.; et al. The Ripoptosome, a signaling platform that assembles in response to genotoxic stress and loss of IAPs. Mol. Cell. 2011, 43, 432-448.
-
(2011)
Mol. Cell.
, vol.43
, pp. 432-448
-
-
Tenev, T.1
Bianchi, K.2
Darding, M.3
Broemer, M.4
Langlais, C.5
Wallberg, F.6
Zachariou, A.7
Lopez, J.8
MacFarlane, M.9
Cain, K.10
-
26
-
-
79960895769
-
The Ripoptosome: Death decision in the cytosol
-
Bertrand, M.J.; Vandenabeele, P. The Ripoptosome: Death decision in the cytosol. Mol. Cell. 2011, 43, 323-325.
-
(2011)
Mol. Cell.
, vol.43
, pp. 323-325
-
-
Bertrand, M.J.1
Vandenabeele, P.2
-
27
-
-
33745242294
-
Involvement of caspase-2 and caspase-9 in endoplasmic reticulum stress-induced apoptosis: A role for the IAPs
-
Cheung, H.H.; Lynn Kelly, N.; Liston, P.; Korneluk, R.G. Involvement of caspase-2 and caspase-9 in endoplasmic reticulum stress-induced apoptosis: A role for the IAPs. Exp. Cell. Res. 2006, 312, 2347-2357.
-
(2006)
Exp. Cell. Res.
, vol.312
, pp. 2347-2357
-
-
Cheung, H.H.1
Lynn Kelly, N.2
Liston, P.3
Korneluk, R.G.4
-
28
-
-
84861877359
-
Caspase-2 is an initiator caspase responsible for pore-forming toxin-mediated apoptosis
-
Imre, G.; Heering, J.; Takeda, A.N.; Husmann, M.; Thiede, B.; zu Heringdorf, D.M.; Green, D.R.; van der Goot, F.G.; Sinha, B. Caspase-2 is an initiator caspase responsible for pore-forming toxin-mediated apoptosis. EMBO J. 2012, 31, 2615-2628.
-
(2012)
EMBO J.
, vol.31
, pp. 2615-2628
-
-
Imre, G.1
Heering, J.2
Takeda, A.N.3
Husmann, M.4
Thiede, B.5
Zu Heringdorf, D.M.6
Green, D.R.7
van der Goot, F.G.8
Sinha, B.9
-
29
-
-
44949233264
-
Caspase-2 cleavage of BID is a critical apoptotic signal downstream of endoplasmic reticulum stress
-
Upton, J.P.; Austgen, K.; Nishino, M.; Coakley, K.M.; Hagen, A.; Han, D.; Papa, F.R.; Oakes, S.A. Caspase-2 cleavage of BID is a critical apoptotic signal downstream of endoplasmic reticulum stress. Mol. Cell. Biol. 2008, 28, 3943-3951.
-
(2008)
Mol. Cell. Biol.
, vol.28
, pp. 3943-3951
-
-
Upton, J.P.1
Austgen, K.2
Nishino, M.3
Coakley, K.M.4
Hagen, A.5
Han, D.6
Papa, F.R.7
Oakes, S.A.8
-
30
-
-
0036163042
-
A conserved tetrapeptide motif: Potentiating apoptosis through IAP-binding
-
Shi, Y. A conserved tetrapeptide motif: Potentiating apoptosis through IAP-binding. Cell. Death Differ. 2002, 9, 93-95.
-
(2002)
Cell. Death Differ.
, vol.9
, pp. 93-95
-
-
Shi, Y.1
-
31
-
-
0037855783
-
Cellular inhibitor of apoptosis 1 and 2 are ubiquitin ligases for the apoptosis inducer Smac/DIABLO
-
Hu, S.; Yang, X. Cellular inhibitor of apoptosis 1 and 2 are ubiquitin ligases for the apoptosis inducer Smac/DIABLO. J. Biol. Chem. 2003, 278, 10055-10060.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 10055-10060
-
-
Hu, S.1
Yang, X.2
-
32
-
-
19944431887
-
Engineering ML-IAP to produce an extraordinarily potent caspase 9 inhibitor: Implications for Smac-dependent anti-apoptotic activity of ML-IAP
-
Vucic, D.; Franklin, M.C.; Wallweber, H.J.; Das, K.; Eckelman, B.P.; Shin, H.; Elliott, L.O.; Kadkhodayan, S.; Deshayes, K.; Salvesen, G.S.; et al. Engineering ML-IAP to produce an extraordinarily potent caspase 9 inhibitor: implications for Smac-dependent anti-apoptotic activity of ML-IAP. Biochem. J. 2005, 385, 11-20.
-
(2005)
Biochem. J.
, vol.385
, pp. 11-20
-
-
Vucic, D.1
Franklin, M.C.2
Wallweber, H.J.3
Das, K.4
Eckelman, B.P.5
Shin, H.6
Elliott, L.O.7
Kadkhodayan, S.8
Deshayes, K.9
Salvesen, G.S.10
-
33
-
-
0034700491
-
Structural basis of IAP recognition by Smac/DIABLO
-
Wu, G.; Chai, J.; Suber, T.L.; Wu, J.W.; Du, C.; Wang, X.; Shi, Y. Structural basis of IAP recognition by Smac/DIABLO. Nature 2000, 408, 1008-1012.
-
(2000)
Nature
, vol.408
, pp. 1008-1012
-
-
Wu, G.1
Chai, J.2
Suber, T.L.3
Wu, J.W.4
Du, C.5
Wang, X.6
Shi, Y.7
-
34
-
-
0034700495
-
Structural basis for binding of Smac/DIABLO to the XIAP BIR3 domain
-
Liu, Z.; Sun, C.; Olejniczak, E.T.; Meadows, R.P.; Betz, S.F.; Oost, T.; Herrmann, J.; Wu, J.C.; Fesik, S.W. Structural basis for binding of Smac/DIABLO to the XIAP BIR3 domain. Nature 2000, 408, 1004-1008.
-
(2000)
Nature
, vol.408
, pp. 1004-1008
-
-
Liu, Z.1
Sun, C.2
Olejniczak, E.T.3
Meadows, R.P.4
Betz, S.F.5
Oost, T.6
Herrmann, J.7
Wu, J.C.8
Fesik, S.W.9
-
35
-
-
33749252583
-
Human inhibitor of apoptosis proteins: Why XIAP is the black sheep of the family
-
Eckelman, B.P.; Salvesen, G.S.; Scott, F.L. Human inhibitor of apoptosis proteins: Why XIAP is the black sheep of the family. EMBO Rep. 2006, 7, 988-994.
-
(2006)
EMBO Rep.
, vol.7
, pp. 988-994
-
-
Eckelman, B.P.1
Salvesen, G.S.2
Scott, F.L.3
-
36
-
-
14844323968
-
XIAP inhibits caspase-3 and-7 using two binding sites: Evolutionarily conserved mechanism of IAPs
-
Scott, F.L.; Denault, J.B.; Riedl, S.J.; Shin, H.; Renatus, M.; Salvesen, G.S. XIAP inhibits caspase-3 and-7 using two binding sites: evolutionarily conserved mechanism of IAPs. EMBO J. 2005, 24, 645-655.
-
(2005)
EMBO J.
, vol.24
, pp. 645-655
-
-
Scott, F.L.1
Denault, J.B.2
Riedl, S.J.3
Shin, H.4
Renatus, M.5
Salvesen, G.S.6
-
37
-
-
0037291737
-
Mechanism of XIAP-mediated inhibition of caspase-9
-
Shiozaki, E.N.; Chai, J.; Rigotti, D.J.; Riedl, S.J.; Li, P.; Srinivasula, S.M.; Alnemri, E.S.; Fairman, R.; Shi, Y. Mechanism of XIAP-mediated inhibition of caspase-9. Mol. Cell. 2003, 11, 519-527.
-
(2003)
Mol. Cell.
, vol.11
, pp. 519-527
-
-
Shiozaki, E.N.1
Chai, J.2
Rigotti, D.J.3
Riedl, S.J.4
Li, P.5
Srinivasula, S.M.6
Alnemri, E.S.7
Fairman, R.8
Shi, Y.9
-
38
-
-
0035831019
-
Structural basis for the inhibition of caspase-3 by XIAP
-
Riedl, S.J.; Renatus, M.; Schwarzenbacher, R.; Zhou, Q.; Sun, C.; Fesik, S.W.; Liddington, R.C.; Salvesen, G.S. Structural basis for the inhibition of caspase-3 by XIAP. Cell 2001, 104, 791-800.
-
(2001)
Cell
, vol.104
, pp. 791-800
-
-
Riedl, S.J.1
Renatus, M.2
Schwarzenbacher, R.3
Zhou, Q.4
Sun, C.5
Fesik, S.W.6
Liddington, R.C.7
Salvesen, G.S.8
-
39
-
-
0035902601
-
Ubiquitin-protein ligase activity of X-linked inhibitor of apoptosis protein promotes proteasomal degradation of caspase-3 and enhances its anti-apoptotic effect in Fas-induced cell death
-
Suzuki, Y.; Nakabayashi, Y.; Takahashi, R. Ubiquitin-protein ligase activity of X-linked inhibitor of apoptosis protein promotes proteasomal degradation of caspase-3 and enhances its anti-apoptotic effect in Fas-induced cell death. Proc. Natl. Acad. Sci. USA 2001, 98, 8662-8667.
-
(2001)
Proc. Natl. Acad. Sci.
, vol.98
, pp. 8662-8667
-
-
Suzuki, Y.1
Nakabayashi, Y.2
Takahashi, R.3
-
40
-
-
17044368875
-
X-linked inhibitor of apoptosis functions as ubiquitin ligase toward mature caspase-9 and cytosolic Smac/DIABLO
-
Morizane, Y.; Honda, R.; Fukami, K.; Yasuda, H. X-linked inhibitor of apoptosis functions as ubiquitin ligase toward mature caspase-9 and cytosolic Smac/DIABLO. J. Biochem. 2005, 137, 125-132.
-
(2005)
J. Biochem.
, vol.137
, pp. 125-132
-
-
Morizane, Y.1
Honda, R.2
Fukami, K.3
Yasuda, H.4
-
41
-
-
78649980427
-
Systematic in vivo RNAi analysis identifies IAPs as NEDD8-E3 ligases
-
Broemer, M.; Tenev, T.; Rigbolt, K.T.; Hempel, S.; Blagoev, B.; Silke, J.; Ditzel, M.; Meier, P. Systematic in vivo RNAi analysis identifies IAPs as NEDD8-E3 ligases. Mol. Cell 2010, 40, 810-822.
-
(2010)
Mol. Cell
, vol.40
, pp. 810-822
-
-
Broemer, M.1
Tenev, T.2
Rigbolt, K.T.3
Hempel, S.4
Blagoev, B.5
Silke, J.6
Ditzel, M.7
Meier, P.8
-
42
-
-
50049110244
-
Regulation of apoptosis by XIAP ubiquitin-ligase activity
-
Schile, A.J.; Garcia-Fernandez, M.; Steller, H. Regulation of apoptosis by XIAP ubiquitin-ligase activity. Genes Dev. 2008, 22, 2256-2266.
-
(2008)
Genes Dev.
, vol.22
, pp. 2256-2266
-
-
Schile, A.J.1
Garcia-Fernandez, M.2
Steller, H.3
-
43
-
-
34547897630
-
XIAP activity dictates Apaf-1 dependency for caspase 9 activation
-
Ho, A.T.; Li, Q.H.; Okada, H.; Mak, T.W.; Zacksenhaus, E. XIAP activity dictates Apaf-1 dependency for caspase 9 activation. Mol. Cell. Biol. 2007, 27, 5673-5685.
-
(2007)
Mol. Cell. Biol.
, vol.27
, pp. 5673-5685
-
-
Ho, A.T.1
Li, Q.H.2
Okada, H.3
Mak, T.W.4
Zacksenhaus, E.5
-
44
-
-
7244245454
-
Decreased apoptosome activity with neuronal differentiation sets the threshold for strict IAP regulation of apoptosis
-
Wright, K.M.; Linhoff, M.W.; Potts, P.R.; Deshmukh, M. Decreased apoptosome activity with neuronal differentiation sets the threshold for strict IAP regulation of apoptosis. J. Cell. Biol. 2004, 167, 303-313.
-
(2004)
J. Cell. Biol.
, vol.167
, pp. 303-313
-
-
Wright, K.M.1
Linhoff, M.W.2
Potts, P.R.3
Deshmukh, M.4
-
45
-
-
29144469495
-
Reduced Apaf-1 levels in cardiomyocytes engage strict regulation of apoptosis by endogenous XIAP
-
Potts, M.B.; Vaughn, A.E.; McDonough, H.; Patterson, C.; Deshmukh, M. Reduced Apaf-1 levels in cardiomyocytes engage strict regulation of apoptosis by endogenous XIAP. J. Cell. Biol. 2005, 171, 925-930.
-
(2005)
J. Cell. Biol.
, vol.171
, pp. 925-930
-
-
Potts, M.B.1
Vaughn, A.E.2
McDonough, H.3
Patterson, C.4
Deshmukh, M.5
-
46
-
-
67649794805
-
The E3 ubiquitin ligase cIAP1 binds and ubiquitinates caspase-3 and-7 via unique mechanisms at distinct steps in their processing
-
Choi, Y.E.; Butterworth, M.; Malladi, S.; Duckett, C.S.; Cohen, G.M.; Bratton, S.B. The E3 ubiquitin ligase cIAP1 binds and ubiquitinates caspase-3 and-7 via unique mechanisms at distinct steps in their processing. J. Biol. Chem. 2009, 284, 12772-12782.
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 12772-12782
-
-
Choi, Y.E.1
Butterworth, M.2
Malladi, S.3
Duckett, C.S.4
Cohen, G.M.5
Bratton, S.B.6
-
47
-
-
0034282432
-
The inhibitor of apoptosis, cIAP2, functions as a ubiquitin-protein ligase and promotes in vitro monoubiquitination of caspases 3 and 7
-
Huang, H.; Joazeiro, C.A.; Bonfoco, E.; Kamada, S.; Leverson, J.D.; Hunter, T. The inhibitor of apoptosis, cIAP2, functions as a ubiquitin-protein ligase and promotes in vitro monoubiquitination of caspases 3 and 7. J. Biol. Chem. 2000, 275, 26661-26664.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 26661-26664
-
-
Huang, H.1
Joazeiro, C.A.2
Bonfoco, E.3
Kamada, S.4
Leverson, J.D.5
Hunter, T.6
-
48
-
-
80053439574
-
Drosophila IAP1-mediated ubiquitylation controls activation of the initiator caspase DRONC independent of protein degradation
-
Lee, T.V.; Fan, Y.; Wang, S.; Srivastava, M.; Broemer, M.; Meier, P.; Bergmann, A. Drosophila IAP1-mediated ubiquitylation controls activation of the initiator caspase DRONC independent of protein degradation. PLoS Genet. 2011, 7, e1002261.
-
(2011)
PLoS Genet.
, vol.7
-
-
Lee, T.V.1
Fan, Y.2
Wang, S.3
Srivastava, M.4
Broemer, M.5
Meier, P.6
Bergmann, A.7
-
49
-
-
77953732998
-
Neuronal apoptosis inhibitory protein, NAIP, is an inhibitor of procaspase-9
-
Davoodi, J.; Ghahremani, M.H.; Es-Haghi, A.; Mohammad-Gholi, A.; Mackenzie, A. Neuronal apoptosis inhibitory protein, NAIP, is an inhibitor of procaspase-9. Int. J. Biochem. Cell. Biol. 2010, 42, 958-964.
-
(2010)
Int. J. Biochem. Cell. Biol.
, vol.42
, pp. 958-964
-
-
Davoodi, J.1
Ghahremani, M.H.2
Es-Haghi, A.3
Mohammad-Gholi, A.4
Mackenzie, A.5
-
50
-
-
36048999753
-
IAP antagonists induce autoubiquitination of c-IAPs, NF-kappaB activation, and TNFalpha-dependent apoptosis
-
Varfolomeev, E.; Blankenship, J.W.; Wayson, S.M.; Fedorova, A.V.; Kayagaki, N.; Garg, P.; Zobel, K.; Dynek, J.N.; Elliott, L.O.; Wallweber, H.J.; et al. IAP antagonists induce autoubiquitination of c-IAPs, NF-kappaB activation, and TNFalpha-dependent apoptosis. Cell 2007, 131, 669-681.
-
(2007)
Cell
, vol.131
, pp. 669-681
-
-
Varfolomeev, E.1
Blankenship, J.W.2
Wayson, S.M.3
Fedorova, A.V.4
Kayagaki, N.5
Garg, P.6
Zobel, K.7
Dynek, J.N.8
Elliott, L.O.9
Wallweber, H.J.10
-
51
-
-
80054837173
-
Antagonists induce a conformational change in cIAP1 that promotes autoubiquitination
-
Dueber, E.C.; Schoeffler, A.J.; Lingel, A.; Elliott, J.M.; Fedorova, A.V.; Giannetti, A.M.; Zobel, K.; Maurer, B.; Varfolomeev, E.; Wu, P.; et al. Antagonists induce a conformational change in cIAP1 that promotes autoubiquitination. Science 2011, 334, 376-380.
-
(2011)
Science
, vol.334
, pp. 376-380
-
-
Dueber, E.C.1
Schoeffler, A.J.2
Lingel, A.3
Elliott, J.M.4
Fedorova, A.V.5
Giannetti, A.M.6
Zobel, K.7
Maurer, B.8
Varfolomeev, E.9
Wu, P.10
-
52
-
-
36148954336
-
IAP Antagonists Target cIAP1 to Induce TNFalpha-Dependent Apoptosis
-
Vince, J.E.; Wong, W.W.; Khan, N.; Feltham, R.; Chau, D.; Ahmed, A.U.; Benetatos, C.A.; Chunduru, S.K.; Condon, S.M.; McKinlay, M.; et al. IAP Antagonists Target cIAP1 to Induce TNFalpha-Dependent Apoptosis. Cell 2007, 131, 682-693.
-
(2007)
Cell
, vol.131
, pp. 682-693
-
-
Vince, J.E.1
Wong, W.W.2
Khan, N.3
Feltham, R.4
Chau, D.5
Ahmed, A.U.6
Benetatos, C.A.7
Chunduru, S.K.8
Condon, S.M.9
McKinlay, M.10
-
53
-
-
54049155149
-
c-IAP1 and c-IAP2 are critical mediators of tumor necrosis factor alpha (TNFalpha)-induced NF-kappaB activation
-
Varfolomeev, E.; Goncharov, T.; Fedorova, A.V.; Dynek, J.N.; Zobel, K.; Deshayes, K.; Fairbrother, W.J.; Vucic, D. c-IAP1 and c-IAP2 are critical mediators of tumor necrosis factor alpha (TNFalpha)-induced NF-kappaB activation. J. Biol. Chem. 2008, 283, 24295-24299.
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 24295-24299
-
-
Varfolomeev, E.1
Goncharov, T.2
Fedorova, A.V.3
Dynek, J.N.4
Zobel, K.5
Deshayes, K.6
Fairbrother, W.J.7
Vucic, D.8
-
54
-
-
79952623655
-
cIAP1 and TAK1 protect cells from TNF-induced necrosis by preventing RIP1/RIP3-dependent reactive oxygen species production
-
Vanlangenakker, N.; Vanden Berghe, T.; Bogaert, P.; Laukens, B.; Zobel, K.; Deshayes, K.; Vucic, D.; Fulda, S.; Vandenabeele, P.; Bertrand, M.J. cIAP1 and TAK1 protect cells from TNF-induced necrosis by preventing RIP1/RIP3-dependent reactive oxygen species production. Cell. Death Differ. 2011, 18, 656-665.
-
(2011)
Cell. Death Differ.
, vol.18
, pp. 656-665
-
-
Vanlangenakker, N.1
vanden Berghe, T.2
Bogaert, P.3
Laukens, B.4
Zobel, K.5
Deshayes, K.6
Vucic, D.7
Fulda, S.8
Vandenabeele, P.9
Bertrand, M.J.10
-
55
-
-
35948994157
-
Autocrine TNFalpha signaling renders human cancer cells susceptible to Smac-mimetic-induced apoptosis
-
Petersen, S.L.; Wang, L.; Yalcin-Chin, A.; Li, L.; Peyton, M.; Minna, J.; Harran, P.; Wang, X. Autocrine TNFalpha signaling renders human cancer cells susceptible to Smac-mimetic-induced apoptosis. Cancer Cell. 2007, 12, 445-456.
-
(2007)
Cancer Cell.
, vol.12
, pp. 445-456
-
-
Petersen, S.L.1
Wang, L.2
Yalcin-Chin, A.3
Li, L.4
Peyton, M.5
Minna, J.6
Harran, P.7
Wang, X.8
-
56
-
-
37549000486
-
A Smac mimetic rescue screen reveals roles for inhibitor of apoptosis proteins in tumor necrosis factor-alpha signaling
-
Gaither, A.; Porter, D.; Yao, Y.; Borawski, J.; Yang, G.; Donovan, J.; Sage, D.; Slisz, J.; Tran, M.; Straub, C.; et al. A Smac mimetic rescue screen reveals roles for inhibitor of apoptosis proteins in tumor necrosis factor-alpha signaling. Cancer Res. 2007, 67, 11493-11498.
-
(2007)
Cancer Res.
, vol.67
, pp. 11493-11498
-
-
Gaither, A.1
Porter, D.2
Yao, Y.3
Borawski, J.4
Yang, G.5
Donovan, J.6
Sage, D.7
Slisz, J.8
Tran, M.9
Straub, C.10
-
57
-
-
47549097367
-
TWEAK-FN14 signaling induces lysosomal degradation of a cIAP1-TRAF2 complex to sensitize tumor cells to TNFalpha
-
Vince, J.E.; Chau, D.; Callus, B.; Wong, W.W.; Hawkins, C.J.; Schneider, P.; McKinlay, M.; Benetatos, C.A.; Condon, S.M.; Chunduru, S.K.; et al. TWEAK-FN14 signaling induces lysosomal degradation of a cIAP1-TRAF2 complex to sensitize tumor cells to TNFalpha. J. Cell. Biol. 2008, 182, 171-184.
-
(2008)
J. Cell. Biol.
, vol.182
, pp. 171-184
-
-
Vince, J.E.1
Chau, D.2
Callus, B.3
Wong, W.W.4
Hawkins, C.J.5
Schneider, P.6
McKinlay, M.7
Benetatos, C.A.8
Condon, S.M.9
Chunduru, S.K.10
-
58
-
-
44949240664
-
cIAP1 and cIAP2 facilitate cancer cell survival by functioning as E3 ligases that promote RIP1 ubiquitination
-
Bertrand, M.J.; Milutinovic, S.; Dickson, K.M.; Ho, W.C.; Boudreault, A.; Durkin, J.; Gillard, J.W.; Jaquith, J.B.; Morris, S.J.; Barker, P.A. cIAP1 and cIAP2 facilitate cancer cell survival by functioning as E3 ligases that promote RIP1 ubiquitination. Mol. Cell. 2008, 30, 689-700.
-
(2008)
Mol. Cell.
, vol.30
, pp. 689-700
-
-
Bertrand, M.J.1
Milutinovic, S.2
Dickson, K.M.3
Ho, W.C.4
Boudreault, A.5
Durkin, J.6
Gillard, J.W.7
Jaquith, J.B.8
Morris, S.J.9
Barker, P.A.10
-
59
-
-
2442559290
-
Receptor interacting protein is ubiquitinated by cellular inhibitor of apoptosis proteins (c-IAP1 and c-IAP2) in vitro
-
Park, S.M.; Yoon, J.B.; Lee, T.H. Receptor interacting protein is ubiquitinated by cellular inhibitor of apoptosis proteins (c-IAP1 and c-IAP2) in vitro. FEBS Lett. 2004, 566, 151-156.
-
(2004)
FEBS Lett.
, vol.566
, pp. 151-156
-
-
Park, S.M.1
Yoon, J.B.2
Lee, T.H.3
-
60
-
-
76149104286
-
Cellular IAPs inhibit a cryptic CD95-induced cell death by limiting RIP1 kinase recruitment
-
Geserick, P.; Hupe, M.; Moulin, M.; Wong, W.W.; Feoktistova, M.; Kellert, B.; Gollnick, H.; Silke, J.; Leverkus, M. Cellular IAPs inhibit a cryptic CD95-induced cell death by limiting RIP1 kinase recruitment. J. Cell. Biol. 2009, 187, 1037-1054.
-
(2009)
J. Cell. Biol.
, vol.187
, pp. 1037-1054
-
-
Geserick, P.1
Hupe, M.2
Moulin, M.3
Wong, W.W.4
Feoktistova, M.5
Kellert, B.6
Gollnick, H.7
Silke, J.8
Leverkus, M.9
-
61
-
-
80052638486
-
cIAP1/2 are direct E3 ligases conjugating diverse types of ubiquitin chains to receptor interacting proteins kinases 1 to 4 (RIP1-4)
-
Bertrand, M.J.; Lippens, S.; Staes, A.; Gilbert, B.; Roelandt, R.; De Medts, J.; Gevaert, K.; Declercq, W.; Vandenabeele, P. cIAP1/2 are direct E3 ligases conjugating diverse types of ubiquitin chains to receptor interacting proteins kinases 1 to 4 (RIP1-4). PLoS One 2011, 6, e22356.
-
(2011)
PLoS One
, vol.6
-
-
Bertrand, M.J.1
Lippens, S.2
Staes, A.3
Gilbert, B.4
Roelandt, R.5
de Medts, J.6
Gevaert, K.7
Declercq, W.8
Vandenabeele, P.9
-
62
-
-
78650300883
-
c-IAP1 and UbcH5 promote K11-linked polyubiquitination of RIP1 in TNF signalling
-
Dynek, J.N.; Goncharov, T.; Dueber, E.C.; Fedorova, A.V.; Izrael-Tomasevic, A.; Phu, L.; Helgason, E.; Fairbrother, W.J.; Deshayes, K.; Kirkpatrick, D.S.; et al. c-IAP1 and UbcH5 promote K11-linked polyubiquitination of RIP1 in TNF signalling. EMBO J. 2010, 29, 4198-4209.
-
(2010)
EMBO J.
, vol.29
, pp. 4198-4209
-
-
Dynek, J.N.1
Goncharov, T.2
Dueber, E.C.3
Fedorova, A.V.4
Izrael-Tomasevic, A.5
Phu, L.6
Helgason, E.7
Fairbrother, W.J.8
Deshayes, K.9
Kirkpatrick, D.S.10
-
63
-
-
77957105977
-
Molecular mechanisms of necroptosis: An ordered cellular explosion
-
Vandenabeele, P.; Galluzzi, L.; Vanden Berghe, T.; Kroemer, G. Molecular mechanisms of necroptosis: an ordered cellular explosion. Nat. Rev. Mol. Cell. Biol. 2010, 11, 700-714.
-
(2010)
Nat. Rev. Mol. Cell. Biol.
, vol.11
, pp. 700-714
-
-
Vandenabeele, P.1
Galluzzi, L.2
vanden Berghe, T.3
Kroemer, G.4
-
64
-
-
84859424337
-
IAPs limit activation of RIP kinases by TNF receptor 1 during development
-
Moulin, M.; Anderton, H.; Voss, A.K.; Thomas, T.; Wong, W.W.; Bankovacki, A.; Feltham, R.; Chau, D.; Cook, W.D.; Silke, J.; et al. IAPs limit activation of RIP kinases by TNF receptor 1 during development. EMBO J. 2012, 31, 1679-1691.
-
(2012)
EMBO J.
, vol.31
, pp. 1679-1691
-
-
Moulin, M.1
Anderton, H.2
Voss, A.K.3
Thomas, T.4
Wong, W.W.5
Bankovacki, A.6
Feltham, R.7
Chau, D.8
Cook, W.D.9
Silke, J.10
-
65
-
-
84856641109
-
NF-kappaB, the first quarter-century: Remarkable progress and outstanding questions
-
Hayden, M.S.; Ghosh, S. NF-kappaB, the first quarter-century: Remarkable progress and outstanding questions. Genes Dev. 2012, 26, 203-234.
-
(2012)
Genes Dev.
, vol.26
, pp. 203-234
-
-
Hayden, M.S.1
Ghosh, S.2
-
66
-
-
62449084941
-
cIAP1, cIAP2, and XIAP act cooperatively via nonredundant pathways to regulate genotoxic stress-induced nuclear factor-kappaB activation
-
Jin, H.S.; Lee, D.H.; Kim, D.H.; Chung, J.H.; Lee, S.J.; Lee, T.H. cIAP1, cIAP2, and XIAP act cooperatively via nonredundant pathways to regulate genotoxic stress-induced nuclear factor-kappaB activation. Cancer Res. 2009, 69, 1782-1791.
-
(2009)
Cancer Res.
, vol.69
, pp. 1782-1791
-
-
Jin, H.S.1
Lee, D.H.2
Kim, D.H.3
Chung, J.H.4
Lee, S.J.5
Lee, T.H.6
-
67
-
-
80052692078
-
LUBAC regulates NF-kappaB activation upon genotoxic stress by promoting linear ubiquitination of NEMO
-
Niu, J.; Shi, Y.; Iwai, K.; Wu, Z.H. LUBAC regulates NF-kappaB activation upon genotoxic stress by promoting linear ubiquitination of NEMO. EMBO J. 2011, 30, 3741-3753.
-
(2011)
EMBO J.
, vol.30
, pp. 3741-3753
-
-
Niu, J.1
Shi, Y.2
Iwai, K.3
Wu, Z.H.4
-
68
-
-
79953240109
-
Linear ubiquitination prevents inflammation and regulates immune signalling
-
Gerlach, B.; Cordier, S.M.; Schmukle, A.C.; Emmerich, C.H.; Rieser, E.; Haas, T.L.; Webb, A.I.; Rickard, J.A.; Anderton, H.; Wong, W.W.; et al. Linear ubiquitination prevents inflammation and regulates immune signalling. Nature 2011, 471, 591-596.
-
(2011)
Nature
, vol.471
, pp. 591-596
-
-
Gerlach, B.1
Cordier, S.M.2
Schmukle, A.C.3
Emmerich, C.H.4
Rieser, E.5
Haas, T.L.6
Webb, A.I.7
Rickard, J.A.8
Anderton, H.9
Wong, W.W.10
-
69
-
-
71149105333
-
Recruitment of the linear ubiquitin chain assembly complex stabilizes the TNF-R1 signaling complex and is required for TNF-mediated gene induction
-
Haas, T.L.; Emmerich, C.H.; Gerlach, B.; Schmukle, A.C.; Cordier, S.M.; Rieser, E.; Feltham, R.; Vince, J.; Warnken, U.; Wenger, T.; et al. Recruitment of the linear ubiquitin chain assembly complex stabilizes the TNF-R1 signaling complex and is required for TNF-mediated gene induction. Mol. Cell 2009, 36, 831-844.
-
(2009)
Mol. Cell
, vol.36
, pp. 831-844
-
-
Haas, T.L.1
Emmerich, C.H.2
Gerlach, B.3
Schmukle, A.C.4
Cordier, S.M.5
Rieser, E.6
Feltham, R.7
Vince, J.8
Warnken, U.9
Wenger, T.10
-
70
-
-
34249799878
-
XIAP induces NF-kappaB activation via the BIR1/TAB1 interaction and BIR1 dimerization
-
Lu, M.; Lin, S.C.; Huang, Y.; Kang, Y.J.; Rich, R.; Lo, Y.C.; Myszka, D.; Han, J.; Wu, H. XIAP induces NF-kappaB activation via the BIR1/TAB1 interaction and BIR1 dimerization. Mol. Cell 2007, 26, 689-702.
-
(2007)
Mol. Cell
, vol.26
, pp. 689-702
-
-
Lu, M.1
Lin, S.C.2
Huang, Y.3
Kang, Y.J.4
Rich, R.5
Lo, Y.C.6
Myszka, D.7
Han, J.8
Wu, H.9
-
71
-
-
77957333810
-
A cytoplasmic ATM-TRAF6-cIAP1 module links nuclear DNA damage signaling to ubiquitin-mediated NF-kappaB activation
-
Hinz, M.; Stilmann, M.; Arslan, S.C.; Khanna, K.K.; Dittmar, G.; Scheidereit, C. A cytoplasmic ATM-TRAF6-cIAP1 module links nuclear DNA damage signaling to ubiquitin-mediated NF-kappaB activation. Mol. Cell. 2010, 40, 63-74.
-
(2010)
Mol. Cell.
, vol.40
, pp. 63-74
-
-
Hinz, M.1
Stilmann, M.2
Arslan, S.C.3
Khanna, K.K.4
Dittmar, G.5
Scheidereit, C.6
-
72
-
-
56349164239
-
Noncanonical NF-kappaB activation requires coordinated assembly of a regulatory complex of the adaptors cIAP1, cIAP2, TRAF2 and TRAF3 and the kinase NIK
-
Zarnegar, B.J.; Wang, Y.; Mahoney, D.J.; Dempsey, P.W.; Cheung, H.H.; He, J.; Shiba, T.; Yang, X.; Yeh, W.C.; Mak, T.W.; et al. Noncanonical NF-kappaB activation requires coordinated assembly of a regulatory complex of the adaptors cIAP1, cIAP2, TRAF2 and TRAF3 and the kinase NIK. Nat. Immunol. 2008, 9, 1371-1378.
-
(2008)
Nat. Immunol.
, vol.9
, pp. 1371-1378
-
-
Zarnegar, B.J.1
Wang, Y.2
Mahoney, D.J.3
Dempsey, P.W.4
Cheung, H.H.5
He, J.6
Shiba, T.7
Yang, X.8
Yeh, W.C.9
Mak, T.W.10
-
73
-
-
56349164232
-
Nonredundant and complementary functions of TRAF2 and TRAF3 in a ubiquitination cascade that activates NIK-dependent alternative NF-kappaB signaling
-
Vallabhapurapu, S.; Matsuzawa, A.; Zhang, W.; Tseng, P.H.; Keats, J.J.; Wang, H.; Vignali, D.A.; Bergsagel, P.L.; Karin, M. Nonredundant and complementary functions of TRAF2 and TRAF3 in a ubiquitination cascade that activates NIK-dependent alternative NF-kappaB signaling. Nat. Immunol. 2008, 9, 1364-1370.
-
(2008)
Nat. Immunol.
, vol.9
, pp. 1364-1370
-
-
Vallabhapurapu, S.1
Matsuzawa, A.2
Zhang, W.3
Tseng, P.H.4
Keats, J.J.5
Wang, H.6
Vignali, D.A.7
Bergsagel, P.L.8
Karin, M.9
-
74
-
-
84861930103
-
Cell division control by the Chromosomal Passenger Complex
-
van der Waal, M.S.; Hengeveld, R.C.; van der Horst, A.; Lens, S.M. Cell division control by the Chromosomal Passenger Complex. Exp. Cell. Res. 2012, 318, 1407-1420.
-
(2012)
Exp. Cell. Res.
, vol.318
, pp. 1407-1420
-
-
van der Waal, M.S.1
Hengeveld, R.C.2
van der Horst, A.3
Lens, S.M.4
-
75
-
-
79960658445
-
Cellular inhibitor of apoptosis protein-1 (cIAP1) can regulate E2F1 transcription factor-mediated control of cyclin transcription
-
Cartier, J.; Berthelet, J.; Marivin, A.; Gemble, S.; Edmond, V.; Plenchette, S.; Lagrange, B.; Hammann, A.; Dupoux, A.; Delva, L.; et al. Cellular inhibitor of apoptosis protein-1 (cIAP1) can regulate E2F1 transcription factor-mediated control of cyclin transcription. J. Biol. Chem. 2011, 286, 26406-26417.
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 26406-26417
-
-
Cartier, J.1
Berthelet, J.2
Marivin, A.3
Gemble, S.4
Edmond, V.5
Plenchette, S.6
Lagrange, B.7
Hammann, A.8
Dupoux, A.9
Delva, L.10
-
76
-
-
4644310311
-
Translocation of the inhibitor of apoptosis protein c-IAP1 from the nucleus to the Golgi in hematopoietic cells undergoing differentiation: A nuclear export signal-mediated event
-
Plenchette, S.; Cathelin, S.; Rebe, C.; Launay, S.; Ladoire, S.; Sordet, O.; Ponnelle, T.; Debili, N.; Phan, T.H.; Padua, R.A.; et al. Translocation of the inhibitor of apoptosis protein c-IAP1 from the nucleus to the Golgi in hematopoietic cells undergoing differentiation: A nuclear export signal-mediated event. Blood 2004, 104, 2035-2043.
-
(2004)
Blood
, vol.104
, pp. 2035-2043
-
-
Plenchette, S.1
Cathelin, S.2
Rebe, C.3
Launay, S.4
Ladoire, S.5
Sordet, O.6
Ponnelle, T.7
Debili, N.8
Phan, T.H.9
Padua, R.A.10
-
77
-
-
42149128194
-
Interaction of heat-shock protein 90 beta isoform (HSP90 beta) with cellular inhibitor of apoptosis 1 (c-IAP1) is required for cell differentiation
-
Didelot, C.; Lanneau, D.; Brunet, M.; Bouchot, A.; Cartier, J.; Jacquel, A.; Ducoroy, P.; Cathelin, S.; Decologne, N.; Chiosis, G.; et al. Interaction of heat-shock protein 90 beta isoform (HSP90 beta) with cellular inhibitor of apoptosis 1 (c-IAP1) is required for cell differentiation. Cell. Death Differ. 2008, 15, 859-866.
-
(2008)
Cell. Death Differ.
, vol.15
, pp. 859-866
-
-
Didelot, C.1
Lanneau, D.2
Brunet, M.3
Bouchot, A.4
Cartier, J.5
Jacquel, A.6
Ducoroy, P.7
Cathelin, S.8
Decologne, N.9
Chiosis, G.10
-
78
-
-
84856338151
-
Regulation of gene transcription by the oncoprotein MYC
-
Luscher, B.; Vervoorts, J. Regulation of gene transcription by the oncoprotein MYC. Gene 2012, 494, 145-160.
-
(2012)
Gene
, vol.494
, pp. 145-160
-
-
Luscher, B.1
Vervoorts, J.2
-
79
-
-
36749047445
-
c-IAP1 cooperates with Myc by acting as a ubiquitin ligase for Mad1
-
Xu, L.; Zhu, J.; Hu, X.; Zhu, H.; Kim, H.T.; LaBaer, J.; Goldberg, A.; Yuan, J. c-IAP1 cooperates with Myc by acting as a ubiquitin ligase for Mad1. Mol. Cell 2007, 28, 914-922.
-
(2007)
Mol. Cell
, vol.28
, pp. 914-922
-
-
Xu, L.1
Zhu, J.2
Hu, X.3
Zhu, H.4
Kim, H.T.5
LaBaer, J.6
Goldberg, A.7
Yuan, J.8
-
80
-
-
0034710543
-
Translational upregulation of X-linked inhibitor of apoptosis (XIAP) increases resistance to radiation induced cell death
-
Holcik, M.; Yeh, C.; Korneluk, R.G.; Chow, T. Translational upregulation of X-linked inhibitor of apoptosis (XIAP) increases resistance to radiation induced cell death. Oncogene 2000, 19, 4174-4177.
-
(2000)
Oncogene
, vol.19
, pp. 4174-4177
-
-
Holcik, M.1
Yeh, C.2
Korneluk, R.G.3
Chow, T.4
-
81
-
-
65349089029
-
Regulation of XIAP translation and induction by MDM2 following irradiation
-
Gu, L.; Zhu, N.; Zhang, H.; Durden, D.L.; Feng, Y.; Zhou, M. Regulation of XIAP translation and induction by MDM2 following irradiation. Cancer Cell. 2009, 15, 363-375.
-
(2009)
Cancer Cell.
, vol.15
, pp. 363-375
-
-
Gu, L.1
Zhu, N.2
Zhang, H.3
Durden, D.L.4
Feng, Y.5
Zhou, M.6
-
82
-
-
0037423208
-
Distinct regulation of internal ribosome entry site-mediated translation following cellular stress is mediated by apoptotic fragments of eIF4G translation initiation factor family members eIF4GI and p97/DAP5/NAT1
-
Nevins, T.A.; Harder, Z.M.; Korneluk, R.G.; Holcík, M. Distinct regulation of internal ribosome entry site-mediated translation following cellular stress is mediated by apoptotic fragments of eIF4G translation initiation factor family members eIF4GI and p97/DAP5/NAT1. J. Biol. Chem. 2003, 278, 3572-3579.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 3572-3579
-
-
Nevins, T.A.1
Harder, Z.M.2
Korneluk, R.G.3
Holcík, M.4
-
83
-
-
84856111924
-
The unfolded protein response: Controlling cell fate decisions under ER stress and beyond
-
Hetz, C. The unfolded protein response: Controlling cell fate decisions under ER stress and beyond. Nat. Rev. Mol. Cell. Biol. 2012, 13, 89-102.
-
(2012)
Nat. Rev. Mol. Cell. Biol.
, vol.13
, pp. 89-102
-
-
Hetz, C.1
-
84
-
-
60149106099
-
PERK-dependent regulation of IAP translation during ER stress
-
Hamanaka, R.B.; Bobrovnikova-Marjon, E.; Ji, X.; Liebhaber, S.A.; Diehl, J.A. PERK-dependent regulation of IAP translation during ER stress. Oncogene 2009, 28, 910-920.
-
(2009)
Oncogene
, vol.28
, pp. 910-920
-
-
Hamanaka, R.B.1
Bobrovnikova-Marjon, E.2
Ji, X.3
Liebhaber, S.A.4
Diehl, J.A.5
-
85
-
-
10344253840
-
Critical role of endogenous Akt/IAPs and MEK1/ERK pathways in counteracting endoplasmic reticulum stress-induced cell death
-
Hu, P.; Han, Z.; Couvillon, A.D.; Exton, J.H. Critical role of endogenous Akt/IAPs and MEK1/ERK pathways in counteracting endoplasmic reticulum stress-induced cell death. J. Biol. Chem. 2004, 279, 49420-49429.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 49420-49429
-
-
Hu, P.1
Han, Z.2
Couvillon, A.D.3
Exton, J.H.4
-
86
-
-
0141643236
-
The polypeptide chain-releasing factor GSPT1/eRF3 is proteolytically processed into an IAP-binding protein
-
Hegde, R.; Srinivasula, S.M.; Datta, P.; Madesh, M.; Wassell, R.; Zhang, Z.; Cheong, N.; Nejmeh, J.; Fernandes-Alnemri, T.; Hoshino, S.; et al. The polypeptide chain-releasing factor GSPT1/eRF3 is proteolytically processed into an IAP-binding protein. J. Biol. Chem. 2003, 278, 38699-38706.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 38699-38706
-
-
Hegde, R.1
Srinivasula, S.M.2
Datta, P.3
Madesh, M.4
Wassell, R.5
Zhang, Z.6
Cheong, N.7
Nejmeh, J.8
Fernandes-Alnemri, T.9
Hoshino, S.10
-
87
-
-
84866540615
-
Redox regulation of protein misfolding, mitochondrial dysfunction, synaptic damage, and cell death in neurodegenerative diseases
-
Nakamura, T.; Cho, D.H.; Lipton, S.A. Redox regulation of protein misfolding, mitochondrial dysfunction, synaptic damage, and cell death in neurodegenerative diseases. Exp. Neurol. 2012, 238, 12-21.
-
(2012)
Exp. Neurol.
, vol.238
, pp. 12-21
-
-
Nakamura, T.1
Cho, D.H.2
Lipton, S.A.3
-
88
-
-
48249110961
-
Nuclear translocation of X-linked inhibitor of apoptosis (XIAP) determines cell fate after hypoxia ischemia in neonatal brain
-
Russell, J.C.; Whiting, H.; Szuflita, N.; Hossain, M.A. Nuclear translocation of X-linked inhibitor of apoptosis (XIAP) determines cell fate after hypoxia ischemia in neonatal brain. J. Neurochem. 2008, 106, 1357-1370.
-
(2008)
J. Neurochem.
, vol.106
, pp. 1357-1370
-
-
Russell, J.C.1
Whiting, H.2
Szuflita, N.3
Hossain, M.A.4
-
89
-
-
77953373213
-
Lack of X-linked inhibitor of apoptosis protein leads to increased apoptosis and tissue loss following neonatal brain injury
-
West, T.; Stump, M.; Lodygensky, G.; Neil, J.J.; Deshmukh, M.; Holtzman, D.M. Lack of X-linked inhibitor of apoptosis protein leads to increased apoptosis and tissue loss following neonatal brain injury. ASN Neuro 2009, 1, 43-53.
-
(2009)
ASN Neuro
, vol.1
, pp. 43-53
-
-
West, T.1
Stump, M.2
Lodygensky, G.3
Neil, J.J.4
Deshmukh, M.5
Holtzman, D.M.6
-
90
-
-
84866170598
-
Sex differences in mechanisms and outcome of neonatal hypoxia-ischemia in rodent models: Implications for sex-specific neuroprotection in clinical neonatal practice
-
Hill, C.A.; Fitch, R.H. Sex differences in mechanisms and outcome of neonatal hypoxia-ischemia in rodent models: Implications for sex-specific neuroprotection in clinical neonatal practice. Neurol. Res. Int. 2012, 2012, 867531-867539.
-
(2012)
Neurol. Res. Int.
, vol.2012
, pp. 867531-867539
-
-
Hill, C.A.1
Fitch, R.H.2
-
91
-
-
33645075706
-
PTD-XIAP protects against cerebral ischemia by anti-apoptotic and transcriptional regulatory mechanisms
-
Guegan, C.; Braudeau, J.; Couriaud, C.; Dietz, G.P.; Lacombe, P.; Bahr, M.; Nosten-Bertrand, M.; Onteniente, B. PTD-XIAP protects against cerebral ischemia by anti-apoptotic and transcriptional regulatory mechanisms. Neurobiol. Dis. 2006, 22, 177-186.
-
(2006)
Neurobiol. Dis.
, vol.22
, pp. 177-186
-
-
Guegan, C.1
Braudeau, J.2
Couriaud, C.3
Dietz, G.P.4
Lacombe, P.5
Bahr, M.6
Nosten-Bertrand, M.7
Onteniente, B.8
-
92
-
-
30444455324
-
In vivo delivery of a XIAP (BIR3-RING) fusion protein containing the protein transduction domain protects against neuronal death induced by seizures
-
Li, T.; Fan, Y.; Luo, Y.; Xiao, B.; Lu, C. In vivo delivery of a XIAP (BIR3-RING) fusion protein containing the protein transduction domain protects against neuronal death induced by seizures. Exp. Neurol. 2006, 197, 301-308.
-
(2006)
Exp. Neurol.
, vol.197
, pp. 301-308
-
-
Li, T.1
Fan, Y.2
Luo, Y.3
Xiao, B.4
Lu, C.5
-
93
-
-
28844482314
-
Apoptosis inhibition in ischemic brain by intraperitoneal PTD-BIR3-RING (XIAP)
-
Fan, Y.F.; Lu, C.Z.; Xie, J.; Zhao, Y.X.; Yang, G.Y. Apoptosis inhibition in ischemic brain by intraperitoneal PTD-BIR3-RING (XIAP). Neurochem. Int. 2006, 48, 50-59.
-
(2006)
Neurochem. Int.
, vol.48
, pp. 50-59
-
-
Fan, Y.F.1
Lu, C.Z.2
Xie, J.3
Zhao, Y.X.4
Yang, G.Y.5
-
94
-
-
36949026130
-
X chromosome-linked inhibitor of apoptosis protein reduces oxidative stress after cerebral irradiation or hypoxia-ischemia through up-regulation of mitochondrial antioxidants
-
Zhu, C.; Xu, F.; Fukuda, A.; Wang, X.; Fukuda, H.; Korhonen, L.; Hagberg, H.; Lannering, B.; Nilsson, M.; Eriksson, P.S.; et al. X chromosome-linked inhibitor of apoptosis protein reduces oxidative stress after cerebral irradiation or hypoxia-ischemia through up-regulation of mitochondrial antioxidants. Eur. J. Neurosci. 2007, 26, 3402-3410.
-
(2007)
Eur. J. Neurosci.
, vol.26
, pp. 3402-3410
-
-
Zhu, C.1
Xu, F.2
Fukuda, A.3
Wang, X.4
Fukuda, H.5
Korhonen, L.6
Hagberg, H.7
Lannering, B.8
Nilsson, M.9
Eriksson, P.S.10
-
95
-
-
35348960414
-
X-linked inhibitor of apoptosis protein increases mitochondrial antioxidants through NF-kappaB activation
-
Kairisalo, M.; Korhonen, L.; Blomgren, K.; Lindholm, D. X-linked inhibitor of apoptosis protein increases mitochondrial antioxidants through NF-kappaB activation. Biochem. Biophys. Res. Commun. 2007, 364, 138-144.
-
(2007)
Biochem. Biophys. Res. Commun.
, vol.364
, pp. 138-144
-
-
Kairisalo, M.1
Korhonen, L.2
Blomgren, K.3
Lindholm, D.4
-
96
-
-
50149083497
-
XIAP regulates intracellular ROS by enhancing antioxidant gene expression
-
Resch, U.; Schichl, Y.M.; Sattler, S.; de Martin, R. XIAP regulates intracellular ROS by enhancing antioxidant gene expression. Biochem. Biophys. Res. Commun. 2008, 375, 156-161.
-
(2008)
Biochem. Biophys. Res. Commun.
, vol.375
, pp. 156-161
-
-
Resch, U.1
Schichl, Y.M.2
Sattler, S.3
de Martin, R.4
-
97
-
-
58249086099
-
COMMD1 expression is controlled by critical residues that determine XIAP binding
-
Maine, G.N.; Mao, X.; Muller, P.A.; Komarck, C.M.; Klomp, L.W.; Burstein, E. COMMD1 expression is controlled by critical residues that determine XIAP binding. Biochem. J. 2009, 417, 601-609.
-
(2009)
Biochem. J.
, vol.417
, pp. 601-609
-
-
Maine, G.N.1
Mao, X.2
Muller, P.A.3
Komarck, C.M.4
Klomp, L.W.5
Burstein, E.6
-
98
-
-
0842307058
-
A novel role for XIAP in copper homeostasis through regulation of MURR1
-
Burstein, E.; Ganesh, L.; Dick, R.D.; van De Sluis, B.; Wilkinson, J.C.; Klomp, L.W.; Wijmenga, C.; Brewer, G.J.; Nabel, G.J.; Duckett, C.S. A novel role for XIAP in copper homeostasis through regulation of MURR1. EMBO J. 2004, 23, 244-254.
-
(2004)
EMBO J.
, vol.23
, pp. 244-254
-
-
Burstein, E.1
Ganesh, L.2
Dick, R.D.3
van de Sluis, B.4
Wilkinson, J.C.5
Klomp, L.W.6
Wijmenga, C.7
Brewer, G.J.8
Nabel, G.J.9
Duckett, C.S.10
-
99
-
-
77950666703
-
Regulation of the copper chaperone CCS by XIAP-mediated ubiquitination
-
Brady, G.F.; Galban, S.; Liu, X.; Basrur, V.; Gitlin, J.D.; Elenitoba-Johnson, K.S.; Wilson, T.E.; Duckett, C.S. Regulation of the copper chaperone CCS by XIAP-mediated ubiquitination. Mol. Cell. Biol. 2010, 30, 1923-1936.
-
(2010)
Mol. Cell. Biol.
, vol.30
, pp. 1923-1936
-
-
Brady, G.F.1
Galban, S.2
Liu, X.3
Basrur, V.4
Gitlin, J.D.5
Elenitoba-Johnson, K.S.6
Wilson, T.E.7
Duckett, C.S.8
-
100
-
-
33644857818
-
XIAP Is a copper binding protein deregulated in Wilson's disease and other copper toxicosis disorders
-
Mufti, A.R.; Burstein, E.; Csomos, R.A.; Graf, P.C.; Wilkinson, J.C.; Dick, R.D.; Challa, M.; Son, J.K.; Bratton, S.B.; Su, G.L.; et al. XIAP Is a copper binding protein deregulated in Wilson's disease and other copper toxicosis disorders. Mol. Cell 2006, 21, 775-785.
-
(2006)
Mol. Cell
, vol.21
, pp. 775-785
-
-
Mufti, A.R.1
Burstein, E.2
Csomos, R.A.3
Graf, P.C.4
Wilkinson, J.C.5
Dick, R.D.6
Challa, M.7
Son, J.K.8
Bratton, S.B.9
Su, G.L.10
-
101
-
-
0034088845
-
The hippocampal neurons of neuronal apoptosis inhibitory protein 1 (NAIP1)-deleted mice display increased vulnerability to kainic acid-induced injury
-
Holcik, M.; Thompson, C.S.; Yaraghi, Z.; Lefebvre, C.A.; MacKenzie, A.E.; Korneluk, R.G. The hippocampal neurons of neuronal apoptosis inhibitory protein 1 (NAIP1)-deleted mice display increased vulnerability to kainic acid-induced injury. Proc. Natl. Acad. Sci. USA 2000, 97, 2286-2290.
-
(2000)
Proc. Natl. Acad. Sci.
, vol.97
, pp. 2286-2290
-
-
Holcik, M.1
Thompson, C.S.2
Yaraghi, Z.3
Lefebvre, C.A.4
MacKenzie, A.E.5
Korneluk, R.G.6
-
102
-
-
0037494727
-
Recent advances in adenovirus-mediated gene therapy for cerebral ischemia
-
Masumu, M.; Hata, R. Recent advances in adenovirus-mediated gene therapy for cerebral ischemia. Curr. Gene Ther. 2003, 3, 43-48.
-
(2003)
Curr. Gene Ther.
, vol.3
, pp. 43-48
-
-
Masumu, M.1
Hata, R.2
-
103
-
-
20044366634
-
IRES in distress: Translational regulation of the inhibitor of apoptosis proteins XIAP and HIAP2 during cell stress
-
Lewis, S.M.; Holcik, M. IRES in distress: Translational regulation of the inhibitor of apoptosis proteins XIAP and HIAP2 during cell stress. Cell. Death Differ. 2005, 12, 547-553.
-
(2005)
Cell. Death Differ.
, vol.12
, pp. 547-553
-
-
Lewis, S.M.1
Holcik, M.2
-
104
-
-
77953421610
-
Monocytes and macrophages regulate immunity through dynamic networks of survival and cell death
-
Parihar, A.; Eubank, T.D.; Doseff, A.I. Monocytes and macrophages regulate immunity through dynamic networks of survival and cell death. J. Innate Immun. 2010, 2, 204-215.
-
(2010)
J. Innate Immun.
, vol.2
, pp. 204-215
-
-
Parihar, A.1
Eubank, T.D.2
Doseff, A.I.3
-
105
-
-
0035863103
-
Resistance of bone marrow-derived macrophages to apoptosis is associated with the expression of X-linked inhibitor of apoptosis protein in primary cultures of bone marrow cells
-
Lin, H.; Chen, C.; Chen, B.D. Resistance of bone marrow-derived macrophages to apoptosis is associated with the expression of X-linked inhibitor of apoptosis protein in primary cultures of bone marrow cells. Biochem. J. 2001, 353, 299-306.
-
(2001)
Biochem. J.
, vol.353
, pp. 299-306
-
-
Lin, H.1
Chen, C.2
Chen, B.D.3
-
106
-
-
0037330987
-
Differential activation of apoptosis regulatory pathways during monocytic vs granulocytic differentiation: A requirement for Bcl-X(L)and XIAP in the prolonged survival of monocytic cells
-
Miranda, M.B.; Dyer, K.F.; Grandis, J.R.; Johnson, D.E. Differential activation of apoptosis regulatory pathways during monocytic vs granulocytic differentiation: A requirement for Bcl-X(L)and XIAP in the prolonged survival of monocytic cells. Leukemia 2003, 17, 390-400.
-
(2003)
Leukemia
, vol.17
, pp. 390-400
-
-
Miranda, M.B.1
Dyer, K.F.2
Grandis, J.R.3
Johnson, D.E.4
-
107
-
-
0033624756
-
Nuclear factor-kappaB and caspases co-operatively regulate the activation and apoptosis of human macrophages
-
Hida, A.; Kawakami, A.; Nakashima, T.; Yamasaki, S.; Sakai, H.; Urayama, S.; Ida, H.; Nakamura, H.; Migita, K.; Kawabe, Y.; et al. Nuclear factor-kappaB and caspases co-operatively regulate the activation and apoptosis of human macrophages. Immunology 2000, 99, 553-560.
-
(2000)
Immunology
, vol.99
, pp. 553-560
-
-
Hida, A.1
Kawakami, A.2
Nakashima, T.3
Yamasaki, S.4
Sakai, H.5
Urayama, S.6
Ida, H.7
Nakamura, H.8
Migita, K.9
Kawabe, Y.10
-
108
-
-
0036057604
-
Activation of the MEK/MAPK pathway is involved in bryostatin1-induced monocytic differenciation and up-regulation of X-linked inhibitor of apoptosis protein
-
Lin, H.; Chen, C.; Li, X.; Chen, B.D. Activation of the MEK/MAPK pathway is involved in bryostatin1-induced monocytic differenciation and up-regulation of X-linked inhibitor of apoptosis protein. Exp. Cell. Res. 2002, 272, 192-198.
-
(2002)
Exp. Cell. Res.
, vol.272
, pp. 192-198
-
-
Lin, H.1
Chen, C.2
Li, X.3
Chen, B.D.4
-
109
-
-
30744452261
-
Inhibitor of apoptosis protein cIAP2 is essential for lipopolysaccharide-induced macrophage survival
-
Conte, D.; Holcik, M.; Lefebvre, C.A.; Lacasse, E.; Picketts, D.J.; Wright, K.E.; Korneluk, R.G. Inhibitor of apoptosis protein cIAP2 is essential for lipopolysaccharide-induced macrophage survival. Mol. Cell. Biol. 2006, 26, 699-708.
-
(2006)
Mol. Cell. Biol.
, vol.26
, pp. 699-708
-
-
Conte, D.1
Holcik, M.2
Lefebvre, C.A.3
Lacasse, E.4
Picketts, D.J.5
Wright, K.E.6
Korneluk, R.G.7
-
110
-
-
0034672626
-
Lipopolysaccharide induces the expression of cellular inhibitor of apoptosis protein-2 in human macrophages
-
Cui, X.; Imaizumi, T.; Yoshida, H.; Tanji, K.; Matsumiya, T.; Satoh, K. Lipopolysaccharide induces the expression of cellular inhibitor of apoptosis protein-2 in human macrophages. Biochim. Biophys. Acta 2000, 1524, 178-182.
-
(2000)
Biochim. Biophys. Acta
, vol.1524
, pp. 178-182
-
-
Cui, X.1
Imaizumi, T.2
Yoshida, H.3
Tanji, K.4
Matsumiya, T.5
Satoh, K.6
-
111
-
-
0036454809
-
Analysis of gene expression during maturation of immature dendritic cells derived from peripheral blood monocytes
-
Matsunaga, T.; Ishida, T.; Takekawa, M.; Nishimura, S.; Adachi, M.; Imai, K. Analysis of gene expression during maturation of immature dendritic cells derived from peripheral blood monocytes. Scand. J. Immunol. 2002, 56, 593-601.
-
(2002)
Scand. J. Immunol.
, vol.56
, pp. 593-601
-
-
Matsunaga, T.1
Ishida, T.2
Takekawa, M.3
Nishimura, S.4
Adachi, M.5
Imai, K.6
-
112
-
-
59449107925
-
cIAP1-dependent TRAF2 degradation regulates the differentiation of monocytes into macrophages and their response to CD40 ligand
-
Dupoux, A.; Cartier, J.; Cathelin, S.; Filomenko, R.; Solary, E.; Dubrez-Daloz, L. cIAP1-dependent TRAF2 degradation regulates the differentiation of monocytes into macrophages and their response to CD40 ligand. Blood 2009, 113, 175-185.
-
(2009)
Blood
, vol.113
, pp. 175-185
-
-
Dupoux, A.1
Cartier, J.2
Cathelin, S.3
Filomenko, R.4
Solary, E.5
Dubrez-Daloz, L.6
-
113
-
-
84860369516
-
Critical role for antiapoptotic Bcl-xL and Mcl-1 in human macrophage survival and cellular IAP1/2 (cIAP1/2) in resistance to HIV-Vpr-induced apoptosis
-
Busca, A.; Saxena, M.; Kumar, A. Critical role for antiapoptotic Bcl-xL and Mcl-1 in human macrophage survival and cellular IAP1/2 (cIAP1/2) in resistance to HIV-Vpr-induced apoptosis. J. Biol. Chem. 2012, 287, 15118-15133.
-
(2012)
J. Biol. Chem.
, vol.287
, pp. 15118-15133
-
-
Busca, A.1
Saxena, M.2
Kumar, A.3
-
114
-
-
33745253109
-
Identification and validation of oncogenes in liver cancer using an integrative oncogenomic approach
-
Zender, L.; Spector, M.S.; Xue, W.; Flemming, P.; Cordon-Cardo, C.; Silke, J.; Fan, S.T.; Luk, J.M.; Wigler, M.; Hannon, G.J.; et al. Identification and validation of oncogenes in liver cancer using an integrative oncogenomic approach. Cell 2006, 125, 1253-1267.
-
(2006)
Cell
, vol.125
, pp. 1253-1267
-
-
Zender, L.1
Spector, M.S.2
Xue, W.3
Flemming, P.4
Cordon-Cardo, C.5
Silke, J.6
Fan, S.T.7
Luk, J.M.8
Wigler, M.9
Hannon, G.J.10
-
115
-
-
65549143221
-
MMP13, Birc2 (cIAP1), and Birc3 (cIAP2), amplified on chromosome 9, collaborate with p53 deficiency in mouse osteosarcoma progression
-
Ma, O.; Cai, W.W.; Zender, L.; Dayaram, T.; Shen, J.; Herron, A.J.; Lowe, S.W.; Man, T.K.; Lau, C.C.; Donehower, L.A. MMP13, Birc2 (cIAP1), and Birc3 (cIAP2), amplified on chromosome 9, collaborate with p53 deficiency in mouse osteosarcoma progression. Cancer Res. 2009, 69, 2559-2567.
-
(2009)
Cancer Res.
, vol.69
, pp. 2559-2567
-
-
Ma, O.1
Cai, W.W.2
Zender, L.3
Dayaram, T.4
Shen, J.5
Herron, A.J.6
Lowe, S.W.7
Man, T.K.8
Lau, C.C.9
Donehower, L.A.10
-
116
-
-
77958510657
-
Rb inactivation accelerates neoplastic growth and substitutes for recurrent amplification of cIAP1, cIAP2 and Yap1 in sporadic mammary carcinoma associated with p53 deficiency
-
Cheng, L.; Zhou, Z.; Flesken-Nikitin, A.; Toshkov, I.A.; Wang, W.; Camps, J.; Ried, T.; Nikitin, A.Y. Rb inactivation accelerates neoplastic growth and substitutes for recurrent amplification of cIAP1, cIAP2 and Yap1 in sporadic mammary carcinoma associated with p53 deficiency. Oncogene 2010, 29, 5700-5711.
-
(2010)
Oncogene
, vol.29
, pp. 5700-5711
-
-
Cheng, L.1
Zhou, Z.2
Flesken-Nikitin, A.3
Toshkov, I.A.4
Wang, W.5
Camps, J.6
Ried, T.7
Nikitin, A.Y.8
-
117
-
-
0036733756
-
Expression of cIAP1, a target for 11q22 amplification, correlates with resistance of cervical cancers to radiotherapy
-
Imoto, I.; Tsuda, H.; Hirasawa, A.; Miura, M.; Sakamoto, M.; Hirohashi, S.; Inazawa, J. Expression of cIAP1, a target for 11q22 amplification, correlates with resistance of cervical cancers to radiotherapy. Cancer Res. 2002, 62, 4860-4866.
-
(2002)
Cancer Res.
, vol.62
, pp. 4860-4866
-
-
Imoto, I.1
Tsuda, H.2
Hirasawa, A.3
Miura, M.4
Sakamoto, M.5
Hirohashi, S.6
Inazawa, J.7
-
118
-
-
0037388691
-
A comprehensive search for DNA amplification in lung cancer identifies inhibitors of apoptosis cIAP1 and cIAP2 as candidate oncogenes
-
Dai, Z.; Zhu, W.G.; Morrison, C.D.; Brena, R.M.; Smiraglia, D.J.; Raval, A.; Wu, Y.Z.; Rush, L.J.; Ross, P.; Molina, J.R.; et al. A comprehensive search for DNA amplification in lung cancer identifies inhibitors of apoptosis cIAP1 and cIAP2 as candidate oncogenes. Hum. Mol. Genet. 2003, 12, 791-801.
-
(2003)
Hum. Mol. Genet.
, vol.12
, pp. 791-801
-
-
Dai, Z.1
Zhu, W.G.2
Morrison, C.D.3
Brena, R.M.4
Smiraglia, D.J.5
Raval, A.6
Wu, Y.Z.7
Rush, L.J.8
Ross, P.9
Molina, J.R.10
-
119
-
-
20544465379
-
Rare amplicons implicate frequent deregulation of cell fate specification pathways in oral squamous cell carcinoma
-
Snijders, A.M.; Schmidt, B.L.; Fridlyand, J.; Dekker, N.; Pinkel, D.; Jordan, R.C.; Albertson, D.G. Rare amplicons implicate frequent deregulation of cell fate specification pathways in oral squamous cell carcinoma. Oncogene 2005, 24, 4232-4242.
-
(2005)
Oncogene
, vol.24
, pp. 4232-4242
-
-
Snijders, A.M.1
Schmidt, B.L.2
Fridlyand, J.3
Dekker, N.4
Pinkel, D.5
Jordan, R.C.6
Albertson, D.G.7
-
120
-
-
0035884398
-
Identification of cIAP1 as a candidate target gene within an amplicon at 11q22 in esophageal squamous cell carcinomas
-
Imoto, I.; Yang, Z.Q.; Pimkhaokham, A.; Tsuda, H.; Shimada, Y.; Imamura, M.; Ohki, M.; Inazawa, J. Identification of cIAP1 as a candidate target gene within an amplicon at 11q22 in esophageal squamous cell carcinomas. Cancer Res. 2001, 61, 6629-6634.
-
(2001)
Cancer Res.
, vol.61
, pp. 6629-6634
-
-
Imoto, I.1
Yang, Z.Q.2
Pimkhaokham, A.3
Tsuda, H.4
Shimada, Y.5
Imamura, M.6
Ohki, M.7
Inazawa, J.8
-
121
-
-
33749389926
-
The inhibitor of apoptosis protein fusion c-IAP2. MALT1 stimulates NF-kappaB activation independently of TRAF1 AND TRAF2
-
Varfolomeev, E.; Wayson, S.M.; Dixit, V.M.; Fairbrother, W.J.; Vucic, D. The inhibitor of apoptosis protein fusion c-IAP2. MALT1 stimulates NF-kappaB activation independently of TRAF1 AND TRAF2. J. Biol. Chem. 2006, 281, 29022-29029.
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 29022-29029
-
-
Varfolomeev, E.1
Wayson, S.M.2
Dixit, V.M.3
Fairbrother, W.J.4
Vucic, D.5
-
122
-
-
64049084627
-
TRAF2-binding BIR1 domain of c-IAP2/MALT1 fusion protein is essential for activation of NF-kappaB
-
Garrison, J.B.; Samuel, T.; Reed, J.C. TRAF2-binding BIR1 domain of c-IAP2/MALT1 fusion protein is essential for activation of NF-kappaB. Oncogene 2009, 28, 1584-1593.
-
(2009)
Oncogene
, vol.28
, pp. 1584-1593
-
-
Garrison, J.B.1
Samuel, T.2
Reed, J.C.3
-
123
-
-
84855357301
-
IAPs regulate the plasticity of cell migration by directly targeting Rac1 for degradation
-
Oberoi, T.K.; Dogan, T.; Hocking, J.C.; Scholz, R.P.; Mooz, J.; Anderson, C.L.; Karreman, C.; Meyer Zu Heringdorf, D.; Schmidt, G.; Ruonala, M.; et al. IAPs regulate the plasticity of cell migration by directly targeting Rac1 for degradation. Embo J. 2011, 31, 14-28.
-
(2011)
Embo J.
, vol.31
, pp. 14-28
-
-
Oberoi, T.K.1
Dogan, T.2
Hocking, J.C.3
Scholz, R.P.4
Mooz, J.5
Anderson, C.L.6
Karreman, C.7
Meyer Zu Heringdorf, D.8
Schmidt, G.9
Ruonala, M.10
-
124
-
-
57049153979
-
X-linked and cellular IAPs modulate the stability of C-RAF kinase and cell motility
-
Dogan, T.; Harms, G.S.; Hekman, M.; Karreman, C.; Oberoi, T.K.; Alnemri, E.S.; Rapp, U.R.; Rajalingam, K. X-linked and cellular IAPs modulate the stability of C-RAF kinase and cell motility. Nat. Cell. Biol. 2008, 10, 1447-1455.
-
(2008)
Nat. Cell. Biol.
, vol.10
, pp. 1447-1455
-
-
Dogan, T.1
Harms, G.S.2
Hekman, M.3
Karreman, C.4
Oberoi, T.K.5
Alnemri, E.S.6
Rapp, U.R.7
Rajalingam, K.8
-
125
-
-
34547660308
-
Promiscuous mutations activate the noncanonical NF-kappaB pathway in multiple myeloma
-
Keats, J.J.; Fonseca, R.; Chesi, M.; Schop, R.; Baker, A.; Chng, W.J.; Van Wier, S.; Tiedemann, R.; Shi, C.X.; Sebag, M.; et al. Promiscuous mutations activate the noncanonical NF-kappaB pathway in multiple myeloma. Cancer Cell. 2007, 12, 131-144.
-
(2007)
Cancer Cell.
, vol.12
, pp. 131-144
-
-
Keats, J.J.1
Fonseca, R.2
Chesi, M.3
Schop, R.4
Baker, A.5
Chng, W.J.6
van Wier, S.7
Tiedemann, R.8
Shi, C.X.9
Sebag, M.10
-
126
-
-
34547562418
-
Frequent engagement of the classical and alternative NF-kappaB pathways by diverse genetic abnormalities in multiple myeloma
-
Annunziata, C.M.; Davis, R.E.; Demchenko, Y.; Bellamy, W.; Gabrea, A.; Zhan, F.; Lenz, G.; Hanamura, I.; Wright, G.; Xiao, W.; et al. Frequent engagement of the classical and alternative NF-kappaB pathways by diverse genetic abnormalities in multiple myeloma. Cancer Cell. 2007, 12, 115-130.
-
(2007)
Cancer Cell.
, vol.12
, pp. 115-130
-
-
Annunziata, C.M.1
Davis, R.E.2
Demchenko, Y.3
Bellamy, W.4
Gabrea, A.5
Zhan, F.6
Lenz, G.7
Hanamura, I.8
Wright, G.9
Xiao, W.10
-
127
-
-
78149356369
-
X-linked lymphoproliferative syndromes: Brothers or distant cousins?
-
Filipovich, A.H.; Zhang, K.; Snow, A.L.; Marsh, R.A. X-linked lymphoproliferative syndromes: brothers or distant cousins? Blood 2010, 116, 3398-3408.
-
(2010)
Blood
, vol.116
, pp. 3398-3408
-
-
Filipovich, A.H.1
Zhang, K.2
Snow, A.L.3
Marsh, R.A.4
-
128
-
-
63849330999
-
S-nitrosylation of XIAP compromises neuronal survival in Parkinson's disease
-
Tsang, A.H.; Lee, Y.I.; Ko, H.S.; Savitt, J.M.; Pletnikova, O.; Troncoso, J.C.; Dawson, V.L.; Dawson, T.M.; Chung, K.K. S-nitrosylation of XIAP compromises neuronal survival in Parkinson's disease. Proc. Natl. Acad. Sci. USA 2009, 106, 4900-4905.
-
(2009)
Proc. Natl. Acad. Sci.
, vol.106
, pp. 4900-4905
-
-
Tsang, A.H.1
Lee, Y.I.2
Ko, H.S.3
Savitt, J.M.4
Pletnikova, O.5
Troncoso, J.C.6
Dawson, V.L.7
Dawson, T.M.8
Chung, K.K.9
-
129
-
-
20444498906
-
Prevention of cytosolic IAPs degradation: A potential pharmacological target in Huntington's Disease
-
Goffredo, D.; Rigamonti, D.; Zuccato, C.; Tartari, M.; Valenza, M.; Cattaneo, E. Prevention of cytosolic IAPs degradation: A potential pharmacological target in Huntington's Disease. Pharmacol. Res. 2005, 52, 140-150.
-
(2005)
Pharmacol. Res.
, vol.52
, pp. 140-150
-
-
Goffredo, D.1
Rigamonti, D.2
Zuccato, C.3
Tartari, M.4
Valenza, M.5
Cattaneo, E.6
-
130
-
-
57349199403
-
Combination of SMN2 copy number and NAIP deletion predicts disease severity in spinal muscular atrophy
-
Watihayati, M.S.; Fatemeh, H.; Marini, M.; Atif, A.B.; Zahiruddin, W.M.; Sasongko, T.H.; Tang, T.H.; Zabidi-Hussin, Z.A.; Nishio, H.; Zilfalil, B.A. Combination of SMN2 copy number and NAIP deletion predicts disease severity in spinal muscular atrophy. Brain Dev. 2009, 31, 42-45.
-
(2009)
Brain Dev.
, vol.31
, pp. 42-45
-
-
Watihayati, M.S.1
Fatemeh, H.2
Marini, M.3
Atif, A.B.4
Zahiruddin, W.M.5
Sasongko, T.H.6
Tang, T.H.7
Zabidi-Hussin, Z.A.8
Nishio, H.9
Zilfalil, B.A.10
-
131
-
-
85117873885
-
Genetic analysis of BIRC4/XIAP as a putative modifier gene of Wilson disease
-
Weiss, K.H.; Runz, H.; Noe, B.; Gotthardt, D.N.; Merle, U.; Ferenci, P.; Stremmel, W.; Fullekrug, J. Genetic analysis of BIRC4/XIAP as a putative modifier gene of Wilson disease. J. Inherit. Metab. Dis. 2010, 10, 1007-1014.
-
(2010)
J. Inherit. Metab. Dis.
, vol.10
, pp. 1007-1014
-
-
Weiss, K.H.1
Runz, H.2
Noe, B.3
Gotthardt, D.N.4
Merle, U.5
Ferenci, P.6
Stremmel, W.7
Fullekrug, J.8
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