Drosophila IAP1-mediated ubiquitylation controls activation of the initiator caspase DRONC independent of protein degradation

PLoS Genetics

Volumn 7, Issue 9, 2011, Pages

  Lee, Tom V ^a   Fan, Yun ^a   Wang, Shiuan ^a,b   Srivastava, Mayank ^a   Broemer, Meike ^c   Meier, Pascal ^c   Bergmann, Andreas ^a,b,d  

^a UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^b BAYLOR COLLEGE OF MEDICINE   (United States)

^c INSTITUTE OF CANCER RESEARCH   (United Kingdom)

^d UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

INHIBITOR OF APOPTOSIS PROTEIN 1; INITIATOR CASPASE; PROTEASOME; PROTEIN DRONC; UNCLASSIFIED DRUG; CASPASE; DROSOPHILA PROTEIN; INHIBITOR OF APOPTOSIS PROTEIN; NC PROTEIN, DROSOPHILA; REAPER PROTEIN, DROSOPHILA; THREAD PROTEIN, DROSOPHILA; UBA1 PROTEIN, DROSOPHILA; UBIQUITIN PROTEIN LIGASE;

APOPTOSIS; ARTICLE; CELL PROTECTION; DRONC GENE; DROSOPHILA; ENZYME ACTIVATION; ENZYME INHIBITION; ENZYME REGULATION; GENE; GENETIC TRANSCRIPTION; IN VITRO STUDY; NONHUMAN; PROTEIN DEGRADATION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PROCESSING; PROTEIN PROTEIN INTERACTION; PROTEIN STABILITY; UBIQUITINATION; ANIMAL; CELL LINE; DROSOPHILA MELANOGASTER; GENETICS; METABOLISM; MUTATION;

INTRACISTERNAL A-PARTICLES;

ANIMALS; APOPTOSIS; CASPASES; CELL LINE; DROSOPHILA MELANOGASTER; DROSOPHILA PROTEINS; INHIBITOR OF APOPTOSIS PROTEINS; MUTATION; PROTEOLYSIS; UBIQUITIN-ACTIVATING ENZYMES; UBIQUITINATION;

EID: 80053439574     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.1002261     Document Type: Article

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