Caspase-2 is an initiator caspase responsible for pore-forming toxin-mediated apoptosis

EMBO Journal

Volumn 31, Issue 11, 2012, Pages 2615-2628

  Imre, Gergely ^a   Heering, Jan ^a   Takeda, Armelle Natsuo ^a   Husmann, Matthias ^b   Thiede, Bernd ^c   Zu Heringdorf, Dagmar Meyer ^d   Green, Douglas R ^e   Van Der Goot, F Gisou ^f   Sinha, Bhanu ^g,h   Dötsch, Volker ^a   Rajalingam, Krishnaraj ^a  

^a GOETHE UNIVERSITY   (Germany)

^b JOHANNES GUTENBERG UNIVERSITY   (Germany)

^c UNIVERSITY OF OSLO   (Norway)

^d GOETHE UNIVERSITY MEDICAL SCHOOL   (Germany)

^e ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

^f EPFL   (Switzerland)

^g UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

^h UNIVERSITY OF WÜRZBURG   (Germany)

Author keywords

apoptosis; caspase; caspase 2; pore forming toxin; staphylococcus

Indexed keywords

AEROLYSIN; BACTERIAL TOXIN; CASPASE 2; STAPHYLOCOCCUS ALPHA TOXIN;

AEROMONAS; APOPTOSIS; ARTICLE; BACTERIAL INFECTION; BACTERIAL VIRULENCE; ENZYME ACTIVATION; ENZYME ANALYSIS; HOST PATHOGEN INTERACTION; HUMAN; NONHUMAN; POTASSIUM TRANSPORT; PRIORITY JOURNAL; PROTEIN FUNCTION; STAPHYLOCOCCUS AUREUS;

APOPTOSIS; BACTERIAL TOXINS; CASPASE 2; CYSTEINE ENDOPEPTIDASES; DOWN-REGULATION; HELA CELLS; HEMOLYSIN PROTEINS; HUMANS; KERATINOCYTES; PORE FORMING CYTOTOXIC PROTEINS; POTASSIUM;

AEROMONAS; BACTERIA (MICROORGANISMS); MAMMALIA; STAPHYLOCOCCUS; STAPHYLOCOCCUS AUREUS;

EID: 84861877359     PISSN: 02614189     EISSN: 14602075     Source Type: Journal    
DOI: 10.1038/emboj.2012.93     Document Type: Article

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