The broccoli-born isothiocyanate sulforaphane impairs nucleotide excision repair: XPA as one potential target

Archives of Toxicology

Volumn 88, Issue 3, 2014, Pages 647-658

  Piberger, Ann Liza ^a   Köberle, Beate ^a   Hartwig, Andrea ^a  

^a KARLSRUHE INSTITUTE OF TECHNOLOGY   (Germany)

Author keywords

Nucleotide excision repair (NER); Sulforaphane; Xeroderma pigmentosum A (XPA) protein; Zinc binding structures

Indexed keywords

ANTINEOPLASTIC AGENT; BENZO[A]PYRENE 7,8 DIHYDRODIOL 9,10 OXIDE; DNA ADDUCT; ISOTHIOCYANIC ACID DERIVATIVE; SULFORAFAN; XERODERMA PIGMENTOSUM GROUP A PROTEIN; XPA PROTEIN, HUMAN; ZINC;

BRASSICA; CELL LINE; CHEMISTRY; DNA ADDUCT; DNA REPAIR; DRUG EFFECTS; GENETICS; HCT116 CELL LINE; HUMAN; METABOLISM; TUMOR SUPPRESSOR GENE;

7,8-DIHYDRO-7,8-DIHYDROXYBENZO(A)PYRENE 9,10-OXIDE; ANTICARCINOGENIC AGENTS; BRASSICA; CELL LINE; DNA ADDUCTS; DNA REPAIR; GENES, P53; HCT116 CELLS; HUMANS; ISOTHIOCYANATES; XERODERMA PIGMENTOSUM GROUP A PROTEIN; ZINC;

EID: 84894575798     PISSN: 03405761     EISSN: 14320738     Source Type: Journal    
DOI: 10.1007/s00204-013-1178-2     Document Type: Article

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